Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01976:Cd300ld'

182661

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Cd300ld

Ensembl Gene

ENSMUSG00000034641

Gene Name

CD300 molecule like family member d

Synonyms

MAIR-IV, 4732429D16Rik, Clm5, Cd300ld1

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL01976

Quality Score

Status

Chromosome

Chromosomal Location

114873269-114880712 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 114878270 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Proline at position 81 (S81P)

Ref Sequence

ENSEMBL: ENSMUSP00000047022 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000045075]

AlphaFold

Q8VCH2

Predicted Effect

probably damaging
Transcript: ENSMUST00000045075
AA Change: S81P

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000047022
Gene: ENSMUSG00000034641
AA Change: S81P

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
IG	25	124	8.85e-5	SMART
transmembrane domain	176	198	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 31 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Alms1	T	C	6: 85,599,647 (GRCm39)	V1960A	possibly damaging	Het
Asph	A	T	4: 9,475,471 (GRCm39)	N537K	probably damaging	Het
Bnip2	T	C	9: 69,908,116 (GRCm39)		probably benign	Het
Cc2d2a	C	A	5: 43,840,457 (GRCm39)	Q104K	probably benign	Het
Clec4a1	T	C	6: 122,905,033 (GRCm39)		probably benign	Het
Dnajb8	T	C	6: 88,199,508 (GRCm39)	S15P	probably damaging	Het
Erp27	C	A	6: 136,896,987 (GRCm39)	V72L	probably damaging	Het
Gpr156	A	G	16: 37,799,395 (GRCm39)	T131A	probably damaging	Het
Grk1	T	C	8: 13,465,993 (GRCm39)	V479A	probably damaging	Het
H2bc1	T	A	13: 24,117,982 (GRCm39)	D53V	possibly damaging	Het
Hspg2	A	G	4: 137,289,237 (GRCm39)	D3784G	probably damaging	Het
Irf2	A	T	8: 47,260,260 (GRCm39)	K26M	probably damaging	Het
Irx6	C	A	8: 93,402,717 (GRCm39)	C27*	probably null	Het
Izumo1r	C	T	9: 14,812,975 (GRCm39)	C99Y	probably damaging	Het
Klrb1a	T	A	6: 128,595,072 (GRCm39)	T132S	probably benign	Het
Mmp13	C	T	9: 7,278,974 (GRCm39)		probably benign	Het
Myo5b	G	A	18: 74,831,348 (GRCm39)	R766Q	probably damaging	Het
Myt1	T	C	2: 181,437,532 (GRCm39)	L81P	probably damaging	Het
Nfat5	G	A	8: 108,094,191 (GRCm39)	V793I	probably damaging	Het
Nup210	A	G	6: 91,030,596 (GRCm39)	V108A	possibly damaging	Het
Omd	T	A	13: 49,743,119 (GRCm39)	Y56*	probably null	Het
Or4b1d	A	G	2: 89,969,268 (GRCm39)	S72P	probably damaging	Het
Pramel27	A	G	4: 143,579,363 (GRCm39)	N316S	probably benign	Het
Psmd9	A	G	5: 123,372,697 (GRCm39)	E60G	probably damaging	Het
Rab11fip1	T	C	8: 27,642,825 (GRCm39)	E658G	possibly damaging	Het
Smchd1	T	A	17: 71,701,720 (GRCm39)	K1091*	probably null	Het
Supt16	A	T	14: 52,419,764 (GRCm39)	N111K	possibly damaging	Het
Trrap	A	G	5: 144,793,799 (GRCm39)	T3666A	probably benign	Het
Ttn	T	C	2: 76,616,095 (GRCm39)	D8289G	probably damaging	Het
Ush2a	T	A	1: 188,643,438 (GRCm39)	S4267T	probably benign	Het
Usp50	T	A	2: 126,551,386 (GRCm39)	E31V	probably benign	Het

Other mutations in Cd300ld

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01628:Cd300ld	APN	11	114,876,999 (GRCm39)	missense	probably benign
IGL02019:Cd300ld	APN	11	114,878,227 (GRCm39)	missense	probably damaging	1.00
IGL02738:Cd300ld	APN	11	114,875,076 (GRCm39)	missense	probably benign	0.40
IGL03386:Cd300ld	APN	11	114,874,998 (GRCm39)	missense	probably benign
R2001:Cd300ld	UTSW	11	114,878,156 (GRCm39)	missense	probably benign	0.44
R2197:Cd300ld	UTSW	11	114,875,058 (GRCm39)	missense	possibly damaging	0.86
R3039:Cd300ld	UTSW	11	114,877,003 (GRCm39)	missense	probably benign
R5540:Cd300ld	UTSW	11	114,878,231 (GRCm39)	missense	probably damaging	1.00
R7096:Cd300ld	UTSW	11	114,878,321 (GRCm39)	missense	possibly damaging	0.92
R7371:Cd300ld	UTSW	11	114,878,186 (GRCm39)	missense	probably damaging	1.00
R7548:Cd300ld	UTSW	11	114,878,248 (GRCm39)	missense	probably benign	0.02
R7710:Cd300ld	UTSW	11	114,875,038 (GRCm39)	missense	probably damaging	1.00
R9211:Cd300ld	UTSW	11	114,878,386 (GRCm39)	missense	probably damaging	1.00
R9396:Cd300ld	UTSW	11	114,878,230 (GRCm39)	missense	probably damaging	1.00

Posted On

2014-05-07