Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02102:Vmn1r124'

279765

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r124

Ensembl Gene

ENSMUSG00000094221

Gene Name

vomeronasal 1 receptor 124

Synonyms

Gm9500

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.058) question?

Stock #

IGL02102

Quality Score

Status

Chromosome

Chromosomal Location

21259694-21260617 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 21260542 bp

Zygosity

Heterozygous

Amino Acid Change

Valine to Isoleucine at position 26 (V26I)

Ref Sequence

ENSEMBL: ENSMUSP00000100835 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000105200]

Predicted Effect

probably benign
Transcript: ENSMUST00000105200
AA Change: V26I

PolyPhen 2 Score 0.005 (Sensitivity: 0.97; Specificity: 0.74)

SMART Domains

Protein: ENSMUSP00000100835
Gene: ENSMUSG00000094221
AA Change: V26I

Domain	Start	End	E-Value	Type
Pfam:TAS2R	8	299	2e-15	PFAM
Pfam:7tm_1	31	293	1.5e-6	PFAM
Pfam:V1R	41	296	5.4e-15	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 45 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adamts9	T	C	6: 92,777,439	T1338A	probably benign	Het
Adcy3	G	A	12: 4,134,699	C125Y	probably damaging	Het
Aoc1	A	T	6: 48,905,962	K257N	probably damaging	Het
Apob	T	C	12: 7,989,407	V497A	possibly damaging	Het
Atp8b5	T	A	4: 43,364,167	V684D	probably benign	Het
AW551984	A	G	9: 39,589,691	W763R	probably damaging	Het
Blm	G	A	7: 80,469,756	T1026M	probably damaging	Het
Cd160	A	G	3: 96,805,570	I126T	possibly damaging	Het
Cdk14	T	C	5: 5,380,083	K15E	probably benign	Het
Cnot6l	T	C	5: 96,091,659	K261R	probably damaging	Het
Cyp3a13	T	G	5: 137,911,603	T153P	probably benign	Het
Ddx24	A	G	12: 103,408,484		probably benign	Het
Dido1	G	A	2: 180,662,247	T1288I	possibly damaging	Het
Dnajc13	A	G	9: 104,229,009	V322A	possibly damaging	Het
Dnajc25	T	A	4: 59,017,693	Y117*	probably null	Het
Dsg1a	A	G	18: 20,332,032	N427D	probably benign	Het
Gabrq	T	G	X: 72,827,545		probably null	Het
Glce	A	G	9: 62,070,601		probably benign	Het
Gm10477	T	C	X: 56,525,401	L45P	probably damaging	Het
Htt	T	A	5: 34,891,481		probably benign	Het
Ift140	A	G	17: 25,033,130	E317G	probably benign	Het
Jak1	A	G	4: 101,159,086	M827T	probably benign	Het
Kalrn	A	G	16: 34,220,222	V932A	probably damaging	Het
Mdm2	A	C	10: 117,692,717	S227R	possibly damaging	Het
Olfr1216	A	G	2: 89,013,126		probably benign	Het
Olfr153	T	C	2: 87,532,461	F143L	probably benign	Het
Olfr305	T	C	7: 86,363,866	Y157C	probably benign	Het
Olfr995	A	G	2: 85,438,267	V297A	probably damaging	Het
Olfr996	G	A	2: 85,579,673	V145I	probably damaging	Het
Pdilt	T	G	7: 119,486,950	E514A	probably benign	Het
Pepd	A	G	7: 34,945,603	D153G	probably damaging	Het
Ptgis	A	T	2: 167,225,447	V70E	probably damaging	Het
Rnf112	T	C	11: 61,452,015	K262E	probably benign	Het
Setd5	G	T	6: 113,150,985	G1300*	probably null	Het
Snx15	A	G	19: 6,122,074	L113P	possibly damaging	Het
Sptbn1	T	C	11: 30,137,427	D1004G	probably damaging	Het
Ston2	A	C	12: 91,639,724	*896G	probably null	Het
Suco	A	G	1: 161,827,705	S1073P	probably damaging	Het
Susd1	A	C	4: 59,369,636	D344E	possibly damaging	Het
Trnt1	G	T	6: 106,778,112		probably null	Het
Ttll12	A	G	15: 83,582,063	F399S	probably damaging	Het
Vmn1r52	T	A	6: 90,179,207	N164K	possibly damaging	Het
Vmn1r56	A	T	7: 5,196,336	M94K	possibly damaging	Het
Vmn1r80	T	C	7: 12,193,691	F243L	probably damaging	Het
Zdhhc8	G	A	16: 18,225,199	S379F	possibly damaging	Het

Other mutations in Vmn1r124

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
FR4976:Vmn1r124	UTSW	7	21259936	missense	possibly damaging	0.49
R0062:Vmn1r124	UTSW	7	21259818	missense	probably benign	0.35
R0671:Vmn1r124	UTSW	7	21260511	missense	probably damaging	0.96
R1305:Vmn1r124	UTSW	7	21260263	missense	probably benign	0.01
R3954:Vmn1r124	UTSW	7	21260523	missense	possibly damaging	0.55
R4628:Vmn1r124	UTSW	7	21260377	nonsense	probably null
R4830:Vmn1r124	UTSW	7	21259699	missense	probably damaging	1.00
R5119:Vmn1r124	UTSW	7	21260247	missense	probably damaging	1.00
R5381:Vmn1r124	UTSW	7	21260398	missense	probably damaging	1.00
R5477:Vmn1r124	UTSW	7	21259728	missense	probably damaging	1.00
R6276:Vmn1r124	UTSW	7	21260179	missense	probably benign	0.03
R6987:Vmn1r124	UTSW	7	21259818	missense	probably benign	0.35
R7151:Vmn1r124	UTSW	7	21260259	missense	probably benign	0.04
R7152:Vmn1r124	UTSW	7	21260259	missense	probably benign	0.04
X0065:Vmn1r124	UTSW	7	21260330	missense	probably benign	0.19

Posted On

2015-04-16