Incidental Mutation 'IGL02306:Sult1d1'
ID287619
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Sult1d1
Ensembl Gene ENSMUSG00000029273
Gene Namesulfotransferase family 1D, member 1
Synonymstyrosine-ester sulfotransferase, Sultn, 5033411P13Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.049) question?
Stock #IGL02306
Quality Score
Status
Chromosome5
Chromosomal Location87554645-87569027 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to A at 87556055 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000108940 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000113314]
PDB Structure
Crystal structure of mouse sulfotransferase SULT1D1 complex with PAP [X-RAY DIFFRACTION]
Crystal structure of mouse cytosolic sulfotransferase mSULT1D1 complex with PAP and p-nitrophenol [X-RAY DIFFRACTION]
Crystal structure of mouse cytosolic sulfotransferase mSULT1D1 complex with PAP and alpha-naphthol [X-RAY DIFFRACTION]
Crystal structure of mouse cytosolic sulfotransferase mSULT1D1 complex with PAPS [X-RAY DIFFRACTION]
Crystal structure of mouse cytosolic sulfotransferase mSULT1D1 complex with PAPS and p-nitrophenyl sulfate [X-RAY DIFFRACTION]
Crystal structure of mouse cytosolic sulfotransferase mSULT1D1 complex with PAPS/PAP and p-nitrophenol [X-RAY DIFFRACTION]
crystal structure of mouse cytosolic sulfotransferase mSULT1D1 complex with PAP and p-nitrophenol, obtained by two-step soaking method [X-RAY DIFFRACTION]
Predicted Effect probably benign
Transcript: ENSMUST00000113314
SMART Domains Protein: ENSMUSP00000108940
Gene: ENSMUSG00000029273

DomainStartEndE-ValueType
Pfam:Sulfotransfer_1 38 288 6e-95 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000166996
Coding Region Coverage
Validation Efficiency
MGI Phenotype PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased benzylic DNA adduct formation in the liver and kidney but increased formation in the colon. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 48 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca4 A G 3: 122,158,395 Y680C probably damaging Het
Abcb11 C T 2: 69,265,457 W846* probably null Het
Adam34 G A 8: 43,650,485 R708C probably benign Het
Adam6a T A 12: 113,545,723 L572Q possibly damaging Het
Aldoart2 A G 12: 55,565,704 Y138C probably damaging Het
Amigo1 T A 3: 108,187,986 F267Y probably benign Het
Car7 A G 8: 104,548,998 Y137C probably damaging Het
Ccar2 A T 14: 70,142,022 M509K probably benign Het
Cd160 A T 3: 96,808,823 I17N possibly damaging Het
Cd163l1 T C 7: 140,223,356 C278R probably damaging Het
Cmya5 C T 13: 93,098,019 G187D probably damaging Het
Crot A T 5: 8,968,701 V555E possibly damaging Het
Cstf1 C T 2: 172,372,971 T4I probably benign Het
Cyp2a12 A G 7: 27,032,583 K250E probably damaging Het
Deaf1 T C 7: 141,324,181 probably null Het
Dse C T 10: 34,160,134 E249K probably damaging Het
E4f1 G T 17: 24,446,929 R88S probably damaging Het
Fam160b2 T C 14: 70,588,997 D217G probably benign Het
Fam83a A C 15: 57,995,308 D248A probably damaging Het
Hadhb T A 5: 30,166,749 L66Q probably null Het
Kalrn T C 16: 34,310,527 E440G probably damaging Het
Kif3b A G 2: 153,320,652 Y527C probably damaging Het
Krt4 T C 15: 101,921,305 I263V probably benign Het
Krtap29-1 A T 11: 99,978,266 V263E probably damaging Het
Mms19 A G 19: 41,966,264 L72P probably damaging Het
Mylpf T A 7: 127,213,158 probably benign Het
Nalcn T A 14: 123,323,338 I776F probably benign Het
Nedd4l T G 18: 65,172,954 S292R possibly damaging Het
Nlrc3 A C 16: 3,964,824 D240E probably damaging Het
Obscn A T 11: 58,999,671 I7345N unknown Het
Olfr1189 A T 2: 88,592,606 K267N probably benign Het
Ostn A T 16: 27,346,941 S127C probably damaging Het
Patl1 A G 19: 11,942,886 K735E possibly damaging Het
Pde12 A G 14: 26,668,378 L392P possibly damaging Het
Plxdc2 A G 2: 16,660,774 I213V probably benign Het
Plxna4 T A 6: 32,206,124 Y948F probably benign Het
Prlhr A T 19: 60,467,915 V71E probably damaging Het
Prlr C T 15: 10,328,674 P412S probably benign Het
Prmt9 A G 8: 77,560,818 K196R probably benign Het
Rundc3a T A 11: 102,400,938 L387Q probably damaging Het
Ryr3 A G 2: 112,847,399 probably null Het
Ryr3 T C 2: 112,834,114 I1611V probably damaging Het
Sfxn2 T A 19: 46,590,548 M240K probably damaging Het
Skor2 T C 18: 76,862,679 S901P probably benign Het
Smad4 T C 18: 73,662,869 probably null Het
Snrnp40 T G 4: 130,365,100 C100W probably benign Het
Spink5 T A 18: 43,964,444 D19E probably damaging Het
Wdr59 G A 8: 111,492,733 L231F probably damaging Het
Other mutations in Sult1d1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02566:Sult1d1 APN 5 87564811 missense probably damaging 0.98
IGL03080:Sult1d1 APN 5 87556988 missense probably benign 0.16
IGL03113:Sult1d1 APN 5 87559879 nonsense probably null
R0269:Sult1d1 UTSW 5 87564802 missense probably damaging 1.00
R1473:Sult1d1 UTSW 5 87564739 missense probably benign 0.13
R2105:Sult1d1 UTSW 5 87559802 missense probably damaging 1.00
R2273:Sult1d1 UTSW 5 87556028 missense probably damaging 1.00
R2919:Sult1d1 UTSW 5 87559755 splice site probably benign
R4416:Sult1d1 UTSW 5 87558576 missense probably damaging 1.00
R4648:Sult1d1 UTSW 5 87566095 missense probably benign 0.00
R5031:Sult1d1 UTSW 5 87559844 missense possibly damaging 0.77
R5108:Sult1d1 UTSW 5 87563869 critical splice donor site probably null
R5905:Sult1d1 UTSW 5 87559826 missense probably damaging 1.00
R5934:Sult1d1 UTSW 5 87559770 frame shift probably null
R6028:Sult1d1 UTSW 5 87559826 missense probably damaging 1.00
Posted On2015-04-16