Incidental Mutation 'IGL02683:Tex44'
ID303434
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tex44
Ensembl Gene ENSMUSG00000036574
Gene Nametestis expressed 44
Synonyms1700019O17Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.073) question?
Stock #IGL02683
Quality Score
Status
Chromosome1
Chromosomal Location86426329-86428052 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 86427743 bp
ZygosityHeterozygous
Amino Acid Change Aspartic acid to Glycine at position 458 (D458G)
Ref Sequence ENSEMBL: ENSMUSP00000136430 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000046004] [ENSMUST00000212541]
Predicted Effect probably benign
Transcript: ENSMUST00000046004
AA Change: D458G

PolyPhen 2 Score 0.010 (Sensitivity: 0.96; Specificity: 0.77)
SMART Domains Protein: ENSMUSP00000136430
Gene: ENSMUSG00000036574
AA Change: D458G

DomainStartEndE-ValueType
internal_repeat_1 60 129 5.56e-9 PROSPERO
Pfam:DUF4678 147 529 4.3e-99 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000212541
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 43 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Aars T C 8: 111,052,531 probably benign Het
Abhd3 A G 18: 10,658,790 S215P probably damaging Het
Adam20 G A 8: 40,795,584 V244M probably damaging Het
Akr1c21 A C 13: 4,576,313 D112A probably damaging Het
Ano6 A T 15: 95,948,312 Y498F probably damaging Het
Aspscr1 T C 11: 120,701,226 F263S probably damaging Het
Capn11 A G 17: 45,653,591 F100S probably damaging Het
Cd63 T C 10: 128,910,430 C9R probably damaging Het
Cenpj T C 14: 56,552,952 K547E possibly damaging Het
Clasp1 A G 1: 118,539,266 D793G probably benign Het
Cmya5 G A 13: 93,090,997 Q2528* probably null Het
Crybg1 A G 10: 43,989,216 S1422P possibly damaging Het
Csgalnact1 C A 8: 68,401,492 G219V probably damaging Het
Dnal1 G A 12: 84,138,354 G178D probably damaging Het
E2f7 T C 10: 110,782,459 M795T probably benign Het
Glipr1l2 T C 10: 112,083,476 V34A probably benign Het
Gm12800 T C 4: 101,910,354 S267P probably benign Het
Gsdmc2 C T 15: 63,833,412 V151M probably damaging Het
Htr7 T C 19: 35,960,362 T448A probably benign Het
Kcnj5 T C 9: 32,317,780 T41A possibly damaging Het
Kcnt1 T C 2: 25,900,925 M12T possibly damaging Het
Kif1c G A 11: 70,726,452 A871T possibly damaging Het
Map3k10 T C 7: 27,658,937 K571R probably damaging Het
Med23 C A 10: 24,870,717 A45E probably benign Het
Nudt5 C A 2: 5,863,601 S103R probably damaging Het
Olfr1154 T A 2: 87,903,104 T191S possibly damaging Het
Parp3 A G 9: 106,473,185 S369P possibly damaging Het
Plxna4 A T 6: 32,517,606 L25Q probably benign Het
Pon2 A G 6: 5,269,062 V204A probably damaging Het
Ppfia1 A G 7: 144,513,358 M463T probably damaging Het
Ppp1r14d T C 2: 119,218,822 E95G probably damaging Het
Prrc2a A G 17: 35,155,993 V1227A probably benign Het
Rabgap1 T A 2: 37,502,939 W536R probably damaging Het
Slco6d1 A G 1: 98,480,672 N431S probably benign Het
Spen C T 4: 141,471,645 V3224I probably benign Het
Srrm1 G A 4: 135,325,104 P658L unknown Het
Ssh2 A G 11: 77,398,256 D88G probably damaging Het
Stat5b T G 11: 100,804,946 K70T probably benign Het
Tut1 T A 19: 8,965,258 C570S probably benign Het
Usp42 T C 5: 143,715,346 E974G possibly damaging Het
Vezf1 A T 11: 88,076,327 Q310L probably benign Het
Vmn2r83 A T 10: 79,491,281 R574S probably benign Het
Zfp664 T C 5: 124,886,322 V260A probably benign Het
Other mutations in Tex44
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02579:Tex44 APN 1 86426447 missense probably benign 0.00
R0589:Tex44 UTSW 1 86427731 missense probably damaging 1.00
R1077:Tex44 UTSW 1 86427055 missense probably benign 0.00
R1468:Tex44 UTSW 1 86427112 missense probably benign 0.16
R1468:Tex44 UTSW 1 86427112 missense probably benign 0.16
R1483:Tex44 UTSW 1 86427186 missense probably damaging 0.99
R1485:Tex44 UTSW 1 86427918 missense possibly damaging 0.72
R1527:Tex44 UTSW 1 86427646 missense probably benign 0.01
R2058:Tex44 UTSW 1 86427006 missense probably damaging 1.00
R2126:Tex44 UTSW 1 86427089 missense probably benign 0.04
R4394:Tex44 UTSW 1 86427767 missense probably benign 0.16
R4524:Tex44 UTSW 1 86427576 missense probably benign 0.03
R6191:Tex44 UTSW 1 86426584 unclassified probably benign
R6658:Tex44 UTSW 1 86427029 missense probably benign 0.01
R6731:Tex44 UTSW 1 86426485 missense probably benign 0.04
R7526:Tex44 UTSW 1 86426515 missense probably benign 0.33
R7625:Tex44 UTSW 1 86426737 nonsense probably null
R8446:Tex44 UTSW 1 86426974 missense possibly damaging 0.92
Posted On2015-04-16