Incidental Mutation 'IGL01417:Anxa13'
ID 80423
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Anxa13
Ensembl Gene ENSMUSG00000055114
Gene Name annexin A13
Synonyms 1810034H17Rik
Accession Numbers
Essential gene? Probably non essential (E-score: 0.153) question?
Stock # IGL01417
Quality Score
Status
Chromosome 15
Chromosomal Location 58204867-58261093 bp(-) (GRCm39)
Type of Mutation exon
DNA Base Change (assembly) T to A at 58228043 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s): [ENSMUST00000068515]
AlphaFold Q99JG3
Predicted Effect noncoding transcript
Transcript: ENSMUST00000068515
SMART Domains Protein: ENSMUSP00000065295
Gene: ENSMUSG00000055114

DomainStartEndE-ValueType
ANX 27 79 1.07e-23 SMART
ANX 99 151 8.37e-26 SMART
low complexity region 192 203 N/A INTRINSIC
ANX 250 302 1.65e-24 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000227274
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The specific function of this gene has not yet been determined; however, it is associated with the plasma membrane of undifferentiated, proliferating endothelial cells and differentiated villus enterocytes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 25 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ctdsp2 T C 10: 126,829,743 (GRCm39) I125T probably benign Het
Dnah7a T C 1: 53,623,759 (GRCm39) K1044E probably benign Het
Edem2 T C 2: 155,570,898 (GRCm39) Y44C probably damaging Het
Elmo1 T C 13: 20,435,345 (GRCm39) probably null Het
Flnb T C 14: 7,905,513 (GRCm38) S1088P probably damaging Het
Fmnl1 A G 11: 103,087,520 (GRCm39) probably benign Het
Fv1 T A 4: 147,953,786 (GRCm39) C117* probably null Het
Hmcn1 T C 1: 150,734,990 (GRCm39) D174G probably damaging Het
Htatip2 G A 7: 49,420,573 (GRCm39) V140I possibly damaging Het
Mill1 G T 7: 17,998,708 (GRCm39) R306L probably benign Het
Myoz2 G A 3: 122,800,081 (GRCm39) T249I possibly damaging Het
Nrdc T C 4: 108,858,027 (GRCm39) probably benign Het
Or2r3 T A 6: 42,449,046 (GRCm39) H22L probably benign Het
Pcbp1 T C 6: 86,502,836 (GRCm39) H21R probably damaging Het
Pdcd2l A C 7: 33,892,170 (GRCm39) L221R probably damaging Het
Ppp1r3b A G 8: 35,851,566 (GRCm39) E135G probably damaging Het
Rbsn T C 6: 92,184,100 (GRCm39) E71G possibly damaging Het
Shc3 T C 13: 51,585,200 (GRCm39) R472G probably benign Het
Sox8 A C 17: 25,786,502 (GRCm39) probably null Het
Tacr3 G T 3: 134,535,242 (GRCm39) W70L possibly damaging Het
Tacr3 A T 3: 134,535,307 (GRCm39) I92F possibly damaging Het
Ubr4 A G 4: 139,138,111 (GRCm39) N1156S probably damaging Het
Upk3b T C 5: 136,067,920 (GRCm39) I37T possibly damaging Het
Vmn1r35 T A 6: 66,656,191 (GRCm39) I160F probably benign Het
Vps50 T C 6: 3,522,377 (GRCm39) probably benign Het
Other mutations in Anxa13
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02192:Anxa13 APN 15 58,220,628 (GRCm39) exon noncoding transcript
IGL02654:Anxa13 APN 15 58,205,397 (GRCm39) splice site noncoding transcript
R1572:Anxa13 UTSW 15 58,220,655 (GRCm39) splice site noncoding transcript
R1973:Anxa13 UTSW 15 58,228,030 (GRCm39) exon noncoding transcript
R1988:Anxa13 UTSW 15 58,205,344 (GRCm39) exon noncoding transcript
R1989:Anxa13 UTSW 15 58,205,344 (GRCm39) exon noncoding transcript
R2916:Anxa13 UTSW 15 58,208,476 (GRCm39) intron noncoding transcript
R4504:Anxa13 UTSW 15 58,228,052 (GRCm39) exon noncoding transcript
R5832:Anxa13 UTSW 15 58,205,389 (GRCm39) splice site noncoding transcript
R6526:Anxa13 UTSW 15 58,208,353 (GRCm39) exon noncoding transcript
Posted On 2013-11-05