Incidental Mutation 'IGL01514:Clec2g'
ID89300
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Clec2g
Ensembl Gene ENSMUSG00000000248
Gene NameC-type lectin domain family 2, member g
Synonyms4632413B12Rik, Ocilrp1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.098) question?
Stock #IGL01514
Quality Score
Status
Chromosome6
Chromosomal Location128934381-128984707 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to A at 128948773 bp
ZygosityHeterozygous
Amino Acid Change Methionine to Isoleucine at position 48 (M48I)
Ref Sequence ENSEMBL: ENSMUSP00000000254 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000000254]
Predicted Effect probably benign
Transcript: ENSMUST00000000254
AA Change: M48I

PolyPhen 2 Score 0.016 (Sensitivity: 0.95; Specificity: 0.79)
SMART Domains Protein: ENSMUSP00000000254
Gene: ENSMUSG00000000248
AA Change: M48I

DomainStartEndE-ValueType
Pfam:Lectin_C 3 108 2.4e-6 PFAM
low complexity region 114 126 N/A INTRINSIC
CLECT 143 254 9.36e-25 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000141700
Predicted Effect noncoding transcript
Transcript: ENSMUST00000146925
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Accs A G 2: 93,839,242 probably benign Het
Actl7b T C 4: 56,740,677 Y227C probably damaging Het
Adam26a A T 8: 43,568,448 H668Q probably benign Het
Alcam A T 16: 52,274,290 probably benign Het
Aldh3a2 C T 11: 61,253,798 probably benign Het
Atp11b G T 3: 35,836,981 G801V probably damaging Het
C3 G A 17: 57,215,866 T1006I probably benign Het
Cacna2d4 T C 6: 119,282,173 probably benign Het
Cldn34b3 A T X: 76,267,074 I83F probably damaging Het
Coch A G 12: 51,603,353 D375G probably damaging Het
Erbb2 C T 11: 98,432,919 T653I possibly damaging Het
Etv3 A G 3: 87,535,718 H203R possibly damaging Het
Fat4 A G 3: 38,949,534 R1801G possibly damaging Het
Gars T A 6: 55,065,520 S413T probably benign Het
Gnat1 G A 9: 107,676,301 R253C possibly damaging Het
Hook3 A T 8: 26,088,189 L91I possibly damaging Het
Lrp8 T C 4: 107,855,684 Y377H probably damaging Het
Lztr1 G A 16: 17,522,391 probably null Het
Malt1 A G 18: 65,476,400 D825G possibly damaging Het
Nlrp9b T C 7: 20,045,934 probably null Het
Olfr1396 A T 11: 49,113,576 I50N probably damaging Het
Olfr54 C T 11: 51,027,589 R196* probably null Het
Orc1 A G 4: 108,602,052 R473G probably damaging Het
Pard6g G A 18: 80,117,446 R258H probably damaging Het
Pkdrej T C 15: 85,818,063 D1224G possibly damaging Het
Polr1e A G 4: 45,018,723 T18A probably benign Het
Pycrl T C 15: 75,917,004 T240A probably damaging Het
Ralgapa1 C A 12: 55,719,657 G1284V probably damaging Het
Rcl1 T C 19: 29,143,298 probably benign Het
Sec24c C T 14: 20,682,771 T134I possibly damaging Het
Sis A G 3: 72,935,920 probably benign Het
Susd5 A C 9: 114,068,879 probably benign Het
Tlk1 T C 2: 70,752,266 N173S probably benign Het
Uroc1 T C 6: 90,363,100 probably benign Het
Other mutations in Clec2g
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00825:Clec2g APN 6 128980181 splice site probably null
IGL00901:Clec2g APN 6 128948692 splice site probably benign
IGL01367:Clec2g APN 6 128948736 missense unknown
IGL02742:Clec2g APN 6 128980261 missense possibly damaging 0.95
R0069:Clec2g UTSW 6 128948753 missense probably benign 0.02
R0069:Clec2g UTSW 6 128980311 critical splice donor site probably null
R0368:Clec2g UTSW 6 128980261 missense possibly damaging 0.95
R1809:Clec2g UTSW 6 128980310 critical splice donor site probably null
R1813:Clec2g UTSW 6 128948697 missense unknown
R2866:Clec2g UTSW 6 128948756 missense probably benign
R4080:Clec2g UTSW 6 128981324 missense probably damaging 0.96
R4732:Clec2g UTSW 6 128981879 nonsense probably null
R4733:Clec2g UTSW 6 128981879 nonsense probably null
R4906:Clec2g UTSW 6 128979448 missense probably benign
R5014:Clec2g UTSW 6 128948802 missense probably benign 0.00
R5220:Clec2g UTSW 6 128981306 missense probably benign 0.00
R5342:Clec2g UTSW 6 128948751 missense probably benign 0.04
R6155:Clec2g UTSW 6 128980273 missense probably damaging 1.00
R6353:Clec2g UTSW 6 128982932 splice site probably null
R6372:Clec2g UTSW 6 128948763 missense probably benign 0.00
R7678:Clec2g UTSW 6 128979437 missense probably damaging 0.96
R7821:Clec2g UTSW 6 128948777 missense probably benign 0.00
Posted On2013-12-03