Incidental Mutation 'IGL01631:Gm13119'
ID93453
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm13119
Ensembl Gene ENSMUSG00000070619
Gene Namepredicted gene 13119
Synonyms
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01631
Quality Score
Status
Chromosome4
Chromosomal Location144357942-144364419 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 144362445 bp
ZygosityHeterozygous
Amino Acid Change Histidine to Arginine at position 111 (H111R)
Ref Sequence ENSEMBL: ENSMUSP00000092103 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000094526]
Predicted Effect probably benign
Transcript: ENSMUST00000094526
AA Change: H111R

PolyPhen 2 Score 0.116 (Sensitivity: 0.93; Specificity: 0.86)
SMART Domains Protein: ENSMUSP00000092103
Gene: ENSMUSG00000070619
AA Change: H111R

DomainStartEndE-ValueType
SCOP:d1a4ya_ 210 414 3e-10 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 40 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4931408C20Rik T C 1: 26,685,414 I228M probably damaging Het
Apip C A 2: 103,073,849 probably benign Het
Arid4a C T 12: 71,022,262 probably benign Het
Brwd1 C A 16: 96,046,466 E98D probably damaging Het
Cactin A G 10: 81,323,224 E303G probably benign Het
Ccdc181 T A 1: 164,280,144 I132K possibly damaging Het
Celsr3 A G 9: 108,837,404 H1995R probably benign Het
Cog4 A G 8: 110,881,840 E756G probably damaging Het
Ctsf T C 19: 4,858,078 L217P probably damaging Het
Dmp1 G T 5: 104,212,868 R470L probably benign Het
Dnajc9 T C 14: 20,388,108 D142G probably benign Het
Ednrb T A 14: 103,843,225 R84S probably benign Het
Gm1110 A T 9: 26,897,916 probably null Het
Has2 A G 15: 56,681,676 S177P possibly damaging Het
Herc6 C T 6: 57,604,107 S264F probably benign Het
Il1rl2 T A 1: 40,356,814 probably null Het
Ltbp2 A G 12: 84,809,146 probably null Het
Map4 A G 9: 110,063,133 probably benign Het
March4 T A 1: 72,452,531 K194* probably null Het
Megf10 A G 18: 57,259,797 D422G possibly damaging Het
Mfsd2a C A 4: 122,949,307 A394S probably benign Het
Mmp27 T C 9: 7,573,288 probably benign Het
Mvd A G 8: 122,434,821 Y370H possibly damaging Het
Olfr1254 T C 2: 89,788,785 D189G probably damaging Het
Olfr922 T A 9: 38,816,039 C179S probably damaging Het
Ptk2 G A 15: 73,216,371 H859Y probably damaging Het
Ptprq T A 10: 107,643,538 E1209D probably benign Het
Rhot1 C T 11: 80,265,774 T636M probably damaging Het
Ripk2 C A 4: 16,163,342 A19S possibly damaging Het
Rsbn1l G A 5: 20,896,571 S657L probably damaging Het
Rsbn1l A T 5: 20,896,572 S657T probably damaging Het
Sema6c A G 3: 95,170,403 T450A probably benign Het
Slc25a1 C T 16: 17,926,066 C262Y probably damaging Het
Slfn3 T C 11: 83,213,535 S288P probably damaging Het
Snrnp200 T A 2: 127,238,824 probably benign Het
Ssu2 T C 6: 112,374,882 Y294C probably damaging Het
Terb1 A G 8: 104,472,864 S483P probably damaging Het
Tsga13 T C 6: 30,913,566 K8E possibly damaging Het
Zbbx T G 3: 75,078,677 D351A probably damaging Het
Zfp454 G T 11: 50,883,735 A37D probably benign Het
Other mutations in Gm13119
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00088:Gm13119 APN 4 144362530 missense possibly damaging 0.91
IGL00485:Gm13119 APN 4 144363442 missense probably damaging 0.99
IGL01025:Gm13119 APN 4 144363377 missense probably damaging 1.00
IGL01102:Gm13119 APN 4 144363625 missense probably benign 0.08
IGL02228:Gm13119 APN 4 144362661 missense probably damaging 1.00
IGL02708:Gm13119 APN 4 144363413 missense probably damaging 1.00
IGL02827:Gm13119 APN 4 144363761 missense probably damaging 1.00
IGL03398:Gm13119 APN 4 144363491 missense probably damaging 1.00
R0403:Gm13119 UTSW 4 144362646 missense probably benign 0.00
R0627:Gm13119 UTSW 4 144362846 missense probably benign 0.03
R0632:Gm13119 UTSW 4 144363782 missense probably damaging 1.00
R1783:Gm13119 UTSW 4 144361725 missense probably benign 0.01
R1895:Gm13119 UTSW 4 144361865 missense probably benign 0.11
R1946:Gm13119 UTSW 4 144361865 missense probably benign 0.11
R2263:Gm13119 UTSW 4 144363541 missense probably benign 0.00
R2389:Gm13119 UTSW 4 144363413 missense probably damaging 1.00
R2435:Gm13119 UTSW 4 144362903 missense possibly damaging 0.75
R3013:Gm13119 UTSW 4 144362455 missense probably damaging 0.98
R3021:Gm13119 UTSW 4 144361799 missense probably damaging 0.99
R3106:Gm13119 UTSW 4 144361676 missense probably benign 0.04
R5237:Gm13119 UTSW 4 144362471 nonsense probably null
R5411:Gm13119 UTSW 4 144361637 start codon destroyed probably null 1.00
R5532:Gm13119 UTSW 4 144363491 missense probably damaging 1.00
R6229:Gm13119 UTSW 4 144363629 missense probably benign 0.03
R6277:Gm13119 UTSW 4 144363653 missense probably damaging 1.00
R6625:Gm13119 UTSW 4 144363799 missense probably damaging 1.00
R6717:Gm13119 UTSW 4 144362657 missense probably benign 0.00
R7103:Gm13119 UTSW 4 144363727 missense probably benign 0.00
R7207:Gm13119 UTSW 4 144361903 missense probably benign 0.08
Posted On2013-12-09