Incidental Mutation 'R1691:Ints1'
| ID |
191774 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ints1
|
| Ensembl Gene |
ENSMUSG00000029547 |
| Gene Name |
integrator complex subunit 1 |
| Synonyms |
1110015K06Rik |
| MMRRC Submission |
039724-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1691 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
139737037-139761429 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 139754687 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 617
(D617E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000143789
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072607]
[ENSMUST00000196864]
[ENSMUST00000200393]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000072607
AA Change: D615E
PolyPhen 2
Score 0.568 (Sensitivity: 0.88; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000072406
Gene: ENSMUSG00000029547
AA Change: D615E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
88 |
102 |
N/A |
INTRINSIC |
|
Pfam:DUF3677
|
379 |
459 |
6.4e-37 |
PFAM |
|
low complexity region
|
854 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
870 |
876 |
N/A |
INTRINSIC |
|
low complexity region
|
946 |
962 |
N/A |
INTRINSIC |
|
low complexity region
|
965 |
988 |
N/A |
INTRINSIC |
|
low complexity region
|
1034 |
1045 |
N/A |
INTRINSIC |
|
low complexity region
|
1058 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1347 |
1361 |
N/A |
INTRINSIC |
|
low complexity region
|
1405 |
1418 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1624 |
N/A |
INTRINSIC |
|
low complexity region
|
1763 |
1776 |
N/A |
INTRINSIC |
|
low complexity region
|
1840 |
1855 |
N/A |
INTRINSIC |
|
low complexity region
|
2062 |
2076 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000184414
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000196319
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000196379
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000196864
|
| SMART Domains |
Protein: ENSMUSP00000142362
Gene: ENSMUSG00000029547
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000197156
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200339
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000200393
AA Change: D617E
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000143789
Gene: ENSMUSG00000029547
AA Change: D617E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
27 |
N/A |
INTRINSIC |
|
low complexity region
|
88 |
102 |
N/A |
INTRINSIC |
|
Pfam:DUF3677
|
379 |
459 |
6.4e-37 |
PFAM |
|
low complexity region
|
854 |
865 |
N/A |
INTRINSIC |
|
low complexity region
|
870 |
876 |
N/A |
INTRINSIC |
|
low complexity region
|
946 |
962 |
N/A |
INTRINSIC |
|
low complexity region
|
965 |
988 |
N/A |
INTRINSIC |
|
low complexity region
|
1034 |
1045 |
N/A |
INTRINSIC |
|
low complexity region
|
1058 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1347 |
1361 |
N/A |
INTRINSIC |
|
low complexity region
|
1405 |
1418 |
N/A |
INTRINSIC |
|
low complexity region
|
1615 |
1624 |
N/A |
INTRINSIC |
|
low complexity region
|
1763 |
1776 |
N/A |
INTRINSIC |
|
low complexity region
|
1840 |
1855 |
N/A |
INTRINSIC |
|
low complexity region
|
2062 |
2076 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 93.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Homozygous mutation of this gene results in embryonic lethality at the blastocyst stage. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(10) : Targeted, knock-out(1) Gene trapped(9) |
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamtsl3 |
T |
C |
7: 82,148,814 (GRCm39) |
S283P |
probably damaging |
Het |
| Adck2 |
T |
A |
6: 39,551,902 (GRCm39) |
L223* |
probably null |
Het |
| Ank |
T |
C |
15: 27,591,030 (GRCm39) |
W390R |
probably damaging |
Het |
| Ano5 |
T |
C |
7: 51,240,327 (GRCm39) |
Y752H |
probably damaging |
Het |
| Apcs |
T |
A |
1: 172,722,160 (GRCm39) |
D62V |
probably damaging |
Het |
| Atad5 |
A |
G |
11: 79,986,358 (GRCm39) |
T482A |
probably benign |
Het |
| Atp7b |
A |
G |
8: 22,501,039 (GRCm39) |
Y955H |
possibly damaging |
Het |
| Ccdc13 |
A |
T |
9: 121,654,134 (GRCm39) |
|
probably null |
Het |
| Ccdc157 |
G |
A |
11: 4,099,030 (GRCm39) |
P159S |
probably benign |
Het |
| Cdhr3 |
C |
T |
12: 33,132,246 (GRCm39) |
V126M |
probably damaging |
Het |
| Cdr1 |
T |
C |
X: 60,227,780 (GRCm39) |
D462G |
possibly damaging |
Het |
| Cisd1 |
A |
G |
10: 71,180,559 (GRCm39) |
V9A |
probably benign |
Het |
| Col19a1 |
T |
C |
1: 24,576,022 (GRCm39) |
R107G |
unknown |
Het |
| Col1a2 |
C |
A |
6: 4,536,038 (GRCm39) |
H972Q |
unknown |
Het |
| Col3a1 |
T |
A |
1: 45,387,776 (GRCm39) |
|
probably benign |
Het |
| Dbnl |
A |
G |
11: 5,747,174 (GRCm39) |
S235G |
probably null |
Het |
| Dock4 |
T |
A |
12: 40,775,754 (GRCm39) |
S566T |
probably benign |
Het |
| Efcab6 |
T |
C |
15: 83,817,407 (GRCm39) |
D722G |
probably benign |
Het |
| Esyt1 |
T |
C |
10: 128,361,403 (GRCm39) |
Q97R |
probably benign |
Het |
| Fat2 |
G |
A |
11: 55,202,678 (GRCm39) |
T132I |
probably damaging |
Het |
| Fgd2 |
C |
T |
17: 29,597,918 (GRCm39) |
Q618* |
probably null |
Het |
| Flnc |
T |
A |
6: 29,441,213 (GRCm39) |
V389E |
probably benign |
Het |
| Garnl3 |
A |
T |
2: 32,887,675 (GRCm39) |
Y778* |
probably null |
Het |
| Gpaa1 |
A |
T |
15: 76,216,416 (GRCm39) |
Y45F |
probably damaging |
Het |
| Grid1 |
A |
T |
14: 35,174,286 (GRCm39) |
I643F |
probably damaging |
Het |
| Gsdmc2 |
T |
C |
15: 63,705,314 (GRCm39) |
D133G |
probably damaging |
Het |
| Hp |
T |
C |
8: 110,302,204 (GRCm39) |
D248G |
probably benign |
Het |
| Hsh2d |
G |
A |
8: 72,954,304 (GRCm39) |
D229N |
probably benign |
Het |
| Ifna13 |
T |
C |
4: 88,562,291 (GRCm39) |
D111G |
probably benign |
Het |
| Il9r |
T |
A |
11: 32,141,829 (GRCm39) |
Q309L |
possibly damaging |
Het |
| Insyn2a |
C |
T |
7: 134,520,015 (GRCm39) |
A172T |
probably damaging |
Het |
| Kcnj12 |
A |
T |
11: 60,961,103 (GRCm39) |
N467I |
possibly damaging |
Het |
| Kmt2e |
T |
A |
5: 23,669,847 (GRCm39) |
D111E |
probably damaging |
Het |
| Lama4 |
A |
G |
10: 38,956,559 (GRCm39) |
K1161E |
probably benign |
Het |
| Lamc1 |
C |
T |
1: 153,122,995 (GRCm39) |
D732N |
probably benign |
Het |
| Larp1 |
A |
G |
11: 57,938,874 (GRCm39) |
T517A |
probably benign |
Het |
| Lrp12 |
A |
G |
15: 39,735,661 (GRCm39) |
I757T |
probably damaging |
Het |
| Max |
T |
C |
12: 77,000,046 (GRCm39) |
D23G |
possibly damaging |
Het |
| Nars1 |
A |
T |
18: 64,649,485 (GRCm39) |
|
probably null |
Het |
| Nipsnap3a |
G |
A |
4: 52,994,185 (GRCm39) |
D91N |
probably null |
Het |
| Nphp3 |
A |
G |
9: 103,880,010 (GRCm39) |
T11A |
probably benign |
Het |
| Nr2c2 |
C |
A |
6: 92,133,673 (GRCm39) |
T226K |
probably damaging |
Het |
| Nrxn1 |
A |
G |
17: 90,469,717 (GRCm39) |
I1288T |
probably damaging |
Het |
| Nt5c1b |
C |
T |
12: 10,425,537 (GRCm39) |
T360I |
possibly damaging |
Het |
| Ofcc1 |
C |
T |
13: 40,362,305 (GRCm39) |
G206R |
probably benign |
Het |
| Or10a3b |
A |
G |
7: 108,444,348 (GRCm39) |
Y290H |
possibly damaging |
Het |
| Or13a21 |
A |
T |
7: 139,998,855 (GRCm39) |
L277Q |
probably damaging |
Het |
| Or4e1 |
A |
T |
14: 52,701,288 (GRCm39) |
H59Q |
possibly damaging |
Het |
| Or4k37 |
G |
A |
2: 111,159,198 (GRCm39) |
V145I |
probably benign |
Het |
| Or6d14 |
A |
G |
6: 116,533,538 (GRCm39) |
T51A |
probably benign |
Het |
| Or9i1b |
C |
T |
19: 13,896,783 (GRCm39) |
T133I |
probably benign |
Het |
| Pcsk1 |
A |
G |
13: 75,280,344 (GRCm39) |
D723G |
possibly damaging |
Het |
| Phrf1 |
C |
A |
7: 140,841,787 (GRCm39) |
Y715* |
probably null |
Het |
| Pigm |
T |
C |
1: 172,204,354 (GRCm39) |
V30A |
probably benign |
Het |
| Pkd1l2 |
A |
T |
8: 117,783,158 (GRCm39) |
F721I |
possibly damaging |
Het |
| Pla2g15 |
A |
G |
8: 106,881,581 (GRCm39) |
D70G |
possibly damaging |
Het |
| Prl7d1 |
A |
T |
13: 27,893,365 (GRCm39) |
I182N |
probably damaging |
Het |
| Prss23 |
T |
C |
7: 89,159,922 (GRCm39) |
K49R |
probably benign |
Het |
| Rps6 |
A |
T |
4: 86,775,046 (GRCm39) |
D19E |
probably benign |
Het |
| Slco6d1 |
A |
T |
1: 98,435,292 (GRCm39) |
H669L |
probably benign |
Het |
| Svil |
G |
T |
18: 5,056,336 (GRCm39) |
C490F |
probably benign |
Het |
| Tom1 |
T |
C |
8: 75,778,227 (GRCm39) |
I103T |
probably damaging |
Het |
| Trim10 |
T |
A |
17: 37,187,791 (GRCm39) |
Y336N |
probably damaging |
Het |
| Trim43c |
G |
T |
9: 88,722,752 (GRCm39) |
V133F |
probably damaging |
Het |
| Tvp23a |
A |
G |
16: 10,246,551 (GRCm39) |
L78P |
possibly damaging |
Het |
| Ugt2b38 |
T |
A |
5: 87,571,991 (GRCm39) |
I14L |
probably benign |
Het |
| Unc5a |
A |
C |
13: 55,150,737 (GRCm39) |
M520L |
probably damaging |
Het |
| Vmn1r174 |
T |
A |
7: 23,453,337 (GRCm39) |
M1K |
probably null |
Het |
| Vmn2r58 |
C |
T |
7: 41,486,913 (GRCm39) |
G661R |
possibly damaging |
Het |
| Vps41 |
A |
C |
13: 19,025,413 (GRCm39) |
D471A |
probably damaging |
Het |
| Zbtb14 |
C |
A |
17: 69,695,497 (GRCm39) |
F398L |
probably damaging |
Het |
| Zfp462 |
T |
A |
4: 55,013,489 (GRCm39) |
F1818L |
possibly damaging |
Het |
| Zp3 |
G |
A |
5: 136,009,135 (GRCm39) |
E50K |
possibly damaging |
Het |
|
| Other mutations in Ints1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01116:Ints1
|
APN |
5 |
139,757,437 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01329:Ints1
|
APN |
5 |
139,753,258 (GRCm39) |
splice site |
probably benign |
|
|
IGL01414:Ints1
|
APN |
5 |
139,744,253 (GRCm39) |
missense |
probably benign |
|
|
IGL01612:Ints1
|
APN |
5 |
139,742,047 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL01726:Ints1
|
APN |
5 |
139,754,166 (GRCm39) |
splice site |
probably benign |
|
|
IGL01958:Ints1
|
APN |
5 |
139,745,843 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL02122:Ints1
|
APN |
5 |
139,750,905 (GRCm39) |
nonsense |
probably null |
|
|
IGL02149:Ints1
|
APN |
5 |
139,737,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02349:Ints1
|
APN |
5 |
139,754,223 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02557:Ints1
|
APN |
5 |
139,757,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02814:Ints1
|
APN |
5 |
139,758,146 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02815:Ints1
|
APN |
5 |
139,741,037 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02825:Ints1
|
APN |
5 |
139,750,494 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL03000:Ints1
|
APN |
5 |
139,752,261 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL03164:Ints1
|
APN |
5 |
139,738,490 (GRCm39) |
missense |
probably damaging |
0.99 |
|
forgiving
|
UTSW |
5 |
139,753,583 (GRCm39) |
missense |
probably damaging |
0.99 |
|
restrained
|
UTSW |
5 |
139,753,481 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
A9681:Ints1
|
UTSW |
5 |
139,755,894 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R0113:Ints1
|
UTSW |
5 |
139,750,968 (GRCm39) |
missense |
|
|
|
R0193:Ints1
|
UTSW |
5 |
139,737,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0372:Ints1
|
UTSW |
5 |
139,758,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1129:Ints1
|
UTSW |
5 |
139,744,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1290:Ints1
|
UTSW |
5 |
139,757,165 (GRCm39) |
nonsense |
probably null |
|
|
R1313:Ints1
|
UTSW |
5 |
139,748,661 (GRCm39) |
missense |
probably benign |
|
|
R1313:Ints1
|
UTSW |
5 |
139,748,661 (GRCm39) |
missense |
probably benign |
|
|
R1708:Ints1
|
UTSW |
5 |
139,748,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1791:Ints1
|
UTSW |
5 |
139,760,277 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2066:Ints1
|
UTSW |
5 |
139,753,251 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2102:Ints1
|
UTSW |
5 |
139,741,754 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R2108:Ints1
|
UTSW |
5 |
139,753,505 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2238:Ints1
|
UTSW |
5 |
139,750,955 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R2426:Ints1
|
UTSW |
5 |
139,757,569 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2913:Ints1
|
UTSW |
5 |
139,743,668 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R3896:Ints1
|
UTSW |
5 |
139,743,399 (GRCm39) |
nonsense |
probably null |
|
|
R4608:Ints1
|
UTSW |
5 |
139,745,599 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4658:Ints1
|
UTSW |
5 |
139,760,054 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4797:Ints1
|
UTSW |
5 |
139,757,631 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4887:Ints1
|
UTSW |
5 |
139,756,911 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4944:Ints1
|
UTSW |
5 |
139,743,847 (GRCm39) |
splice site |
probably null |
|
|
R4956:Ints1
|
UTSW |
5 |
139,742,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4976:Ints1
|
UTSW |
5 |
139,738,566 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5283:Ints1
|
UTSW |
5 |
139,750,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5354:Ints1
|
UTSW |
5 |
139,752,183 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5496:Ints1
|
UTSW |
5 |
139,740,953 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5517:Ints1
|
UTSW |
5 |
139,738,542 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5696:Ints1
|
UTSW |
5 |
139,740,744 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5766:Ints1
|
UTSW |
5 |
139,757,900 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6359:Ints1
|
UTSW |
5 |
139,741,972 (GRCm39) |
missense |
probably benign |
0.09 |
|
R6753:Ints1
|
UTSW |
5 |
139,750,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6892:Ints1
|
UTSW |
5 |
139,753,583 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7009:Ints1
|
UTSW |
5 |
139,754,217 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7047:Ints1
|
UTSW |
5 |
139,744,226 (GRCm39) |
nonsense |
probably null |
|
|
R7216:Ints1
|
UTSW |
5 |
139,754,739 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7220:Ints1
|
UTSW |
5 |
139,747,828 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7263:Ints1
|
UTSW |
5 |
139,749,834 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7291:Ints1
|
UTSW |
5 |
139,750,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7319:Ints1
|
UTSW |
5 |
139,746,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7411:Ints1
|
UTSW |
5 |
139,750,015 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7497:Ints1
|
UTSW |
5 |
139,754,731 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7529:Ints1
|
UTSW |
5 |
139,753,481 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7710:Ints1
|
UTSW |
5 |
139,756,840 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7816:Ints1
|
UTSW |
5 |
139,757,134 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7819:Ints1
|
UTSW |
5 |
139,746,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7992:Ints1
|
UTSW |
5 |
139,742,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Ints1
|
UTSW |
5 |
139,750,968 (GRCm39) |
missense |
|
|
|
R8265:Ints1
|
UTSW |
5 |
139,757,919 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8782:Ints1
|
UTSW |
5 |
139,744,952 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9016:Ints1
|
UTSW |
5 |
139,744,326 (GRCm39) |
missense |
probably benign |
|
|
R9053:Ints1
|
UTSW |
5 |
139,747,822 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R9056:Ints1
|
UTSW |
5 |
139,760,041 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9080:Ints1
|
UTSW |
5 |
139,739,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9086:Ints1
|
UTSW |
5 |
139,743,947 (GRCm39) |
missense |
probably benign |
|
|
R9122:Ints1
|
UTSW |
5 |
139,745,930 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9134:Ints1
|
UTSW |
5 |
139,743,351 (GRCm39) |
missense |
probably benign |
|
|
R9135:Ints1
|
UTSW |
5 |
139,737,701 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R9169:Ints1
|
UTSW |
5 |
139,748,586 (GRCm39) |
missense |
probably benign |
|
|
R9280:Ints1
|
UTSW |
5 |
139,750,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9458:Ints1
|
UTSW |
5 |
139,743,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9666:Ints1
|
UTSW |
5 |
139,748,217 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Ints1
|
UTSW |
5 |
139,757,393 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCGGACAATGATTGCCTTGGAG -3'
(R):5'- ACTGTCAGCCGTGGACGTAAAAC -3'
Sequencing Primer
(F):5'- CTTGGAGGTGATGGCTCCC -3'
(R):5'- TTGCACGTCCCTGGAAAC -3'
|
| Posted On |
2014-05-14 |
Incidental Mutation