Incidental Mutation 'R1758:Myom2'
| ID |
195087 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myom2
|
| Ensembl Gene |
ENSMUSG00000031461 |
| Gene Name |
myomesin 2 |
| Synonyms |
|
| MMRRC Submission |
039790-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.149)
|
| Stock # |
R1758 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
8 |
| Chromosomal Location |
15107653-15183410 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 15115795 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 70
(L70P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000033842
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000033842]
|
| AlphaFold |
Q14BI5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000033842
AA Change: L70P
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000033842
Gene: ENSMUSG00000031461
AA Change: L70P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
34 |
63 |
N/A |
INTRINSIC |
|
low complexity region
|
79 |
87 |
N/A |
INTRINSIC |
|
coiled coil region
|
97 |
129 |
N/A |
INTRINSIC |
|
IG
|
160 |
247 |
7.7e-5 |
SMART |
|
IG
|
284 |
373 |
8.01e-3 |
SMART |
|
FN3
|
383 |
466 |
1.5e-14 |
SMART |
|
FN3
|
511 |
594 |
1.79e-12 |
SMART |
|
FN3
|
612 |
693 |
1.95e-13 |
SMART |
|
FN3
|
711 |
794 |
8.69e-11 |
SMART |
|
FN3
|
813 |
896 |
1.86e-10 |
SMART |
|
IG_like
|
913 |
999 |
1.58e2 |
SMART |
|
Blast:IG_like
|
1021 |
1106 |
1e-44 |
BLAST |
|
IG_like
|
1135 |
1215 |
2.27e1 |
SMART |
|
Blast:IG_like
|
1227 |
1321 |
9e-51 |
BLAST |
|
IGc2
|
1357 |
1425 |
4.96e-8 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000131251
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135908
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 97.0%
- 10x: 95.6%
- 20x: 93.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The giant protein titin, together with its associated proteins, interconnects the major structure of sarcomeres, the M bands and Z discs. The C-terminal end of the titin string extends into the M line, where it binds tightly to M-band constituents of apparent molecular masses of 190 kD and 165 kD. The predicted MYOM2 protein contains 1,465 amino acids. Like MYOM1, MYOM2 has a unique N-terminal domain followed by 12 repeat domains with strong homology to either fibronectin type III or immunoglobulin C2 domains. Protein sequence comparisons suggested that the MYOM2 protein and bovine M protein are identical. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 95 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700029H14Rik |
T |
C |
8: 13,612,237 (GRCm39) |
R38G |
possibly damaging |
Het |
| 4930590J08Rik |
T |
C |
6: 91,892,203 (GRCm39) |
V155A |
possibly damaging |
Het |
| Adgb |
A |
G |
10: 10,302,349 (GRCm39) |
S406P |
probably damaging |
Het |
| Adgrb2 |
C |
A |
4: 129,905,668 (GRCm39) |
T893N |
probably damaging |
Het |
| Adgrf5 |
T |
C |
17: 43,735,484 (GRCm39) |
|
probably null |
Het |
| Alms1 |
T |
A |
6: 85,605,487 (GRCm39) |
I2379N |
probably damaging |
Het |
| Arap3 |
C |
T |
18: 38,122,965 (GRCm39) |
V512I |
probably benign |
Het |
| Atf4 |
C |
T |
15: 80,141,414 (GRCm39) |
T268I |
probably benign |
Het |
| Cblif |
G |
A |
19: 11,735,179 (GRCm39) |
M266I |
probably damaging |
Het |
| Ccdc154 |
T |
C |
17: 25,382,156 (GRCm39) |
L25P |
probably damaging |
Het |
| Ccdc9 |
G |
A |
7: 16,010,161 (GRCm39) |
S381F |
probably damaging |
Het |
| Cdk17 |
C |
T |
10: 93,044,112 (GRCm39) |
T17M |
probably damaging |
Het |
| Cep128 |
T |
C |
12: 91,314,352 (GRCm39) |
N142S |
probably benign |
Het |
| Cep78 |
A |
G |
19: 15,936,900 (GRCm39) |
I602T |
probably damaging |
Het |
| Clasp1 |
C |
T |
1: 118,475,755 (GRCm39) |
T935I |
probably damaging |
Het |
| Cnr1 |
T |
C |
4: 33,945,000 (GRCm39) |
S463P |
probably damaging |
Het |
| Cntnap1 |
T |
A |
11: 101,075,449 (GRCm39) |
W876R |
probably damaging |
Het |
| Cntnap5c |
A |
G |
17: 58,349,545 (GRCm39) |
D286G |
probably damaging |
Het |
| Copa |
C |
T |
1: 171,931,711 (GRCm39) |
R321C |
probably damaging |
Het |
| Cspg4b |
A |
G |
13: 113,505,266 (GRCm39) |
T2132A |
possibly damaging |
Het |
| Ctla2a |
T |
G |
13: 61,083,256 (GRCm39) |
E98A |
probably damaging |
Het |
| Cux1 |
A |
T |
5: 136,421,176 (GRCm39) |
D183E |
probably damaging |
Het |
| Cxcl15 |
A |
C |
5: 90,949,323 (GRCm39) |
T163P |
unknown |
Het |
| Ddias |
T |
C |
7: 92,508,571 (GRCm39) |
N448S |
probably benign |
Het |
| Dhx8 |
T |
C |
11: 101,657,564 (GRCm39) |
F1152S |
probably damaging |
Het |
| Dnah12 |
C |
A |
14: 26,488,071 (GRCm39) |
Q992K |
probably benign |
Het |
| Eno3 |
G |
T |
11: 70,552,251 (GRCm39) |
W301L |
possibly damaging |
Het |
| Faap100 |
A |
T |
11: 120,268,059 (GRCm39) |
V238E |
probably damaging |
Het |
| Fgf4 |
A |
G |
7: 144,416,049 (GRCm39) |
S137G |
probably benign |
Het |
| Fhod3 |
A |
C |
18: 25,253,367 (GRCm39) |
D1439A |
possibly damaging |
Het |
| Frem2 |
A |
G |
3: 53,560,778 (GRCm39) |
L1243P |
probably damaging |
Het |
| Gkn3 |
T |
G |
6: 87,365,817 (GRCm39) |
M1L |
probably benign |
Het |
| Gm10250 |
T |
C |
15: 5,150,509 (GRCm39) |
|
probably benign |
Het |
| Gm12185 |
T |
C |
11: 48,798,859 (GRCm39) |
T545A |
possibly damaging |
Het |
| Gm14226 |
T |
A |
2: 154,867,378 (GRCm39) |
L445H |
probably damaging |
Het |
| Gm3404 |
A |
T |
5: 146,463,036 (GRCm39) |
M73L |
probably benign |
Het |
| Gm973 |
G |
T |
1: 59,673,169 (GRCm39) |
R976S |
unknown |
Het |
| Gpr146 |
A |
T |
5: 139,379,137 (GRCm39) |
H313L |
probably benign |
Het |
| Gys2 |
T |
A |
6: 142,418,432 (GRCm39) |
E32D |
probably damaging |
Het |
| Igsf10 |
G |
A |
3: 59,236,617 (GRCm39) |
T1188I |
probably benign |
Het |
| Igsf9b |
A |
T |
9: 27,245,548 (GRCm39) |
T1172S |
possibly damaging |
Het |
| Itga8 |
T |
A |
2: 12,270,144 (GRCm39) |
N114I |
possibly damaging |
Het |
| Itsn2 |
T |
A |
12: 4,708,160 (GRCm39) |
V795E |
possibly damaging |
Het |
| Kdm1b |
T |
A |
13: 47,214,244 (GRCm39) |
S197T |
probably benign |
Het |
| Kif5c |
G |
A |
2: 49,613,145 (GRCm39) |
R161Q |
probably benign |
Het |
| Krt33b |
T |
C |
11: 99,916,361 (GRCm39) |
Y232C |
probably damaging |
Het |
| Lonrf2 |
G |
A |
1: 38,852,357 (GRCm39) |
P165S |
probably benign |
Het |
| Lrp1 |
A |
T |
10: 127,424,453 (GRCm39) |
N744K |
possibly damaging |
Het |
| Mcm10 |
C |
A |
2: 5,008,861 (GRCm39) |
L369F |
probably damaging |
Het |
| Muc5ac |
T |
A |
7: 141,355,268 (GRCm39) |
I1018N |
possibly damaging |
Het |
| Myt1l |
T |
A |
12: 29,877,241 (GRCm39) |
N297K |
unknown |
Het |
| Ncr1 |
C |
T |
7: 4,343,807 (GRCm39) |
T98I |
probably benign |
Het |
| Nek3 |
T |
C |
8: 22,650,278 (GRCm39) |
E78G |
probably damaging |
Het |
| Nfatc3 |
T |
A |
8: 106,825,768 (GRCm39) |
N606K |
probably damaging |
Het |
| Nup107 |
T |
G |
10: 117,597,248 (GRCm39) |
D669A |
probably damaging |
Het |
| Or10ag52 |
A |
T |
2: 87,043,758 (GRCm39) |
Q174L |
probably benign |
Het |
| Or10c1 |
A |
T |
17: 37,522,204 (GRCm39) |
I180N |
possibly damaging |
Het |
| Or4c3 |
T |
C |
2: 89,851,673 (GRCm39) |
T246A |
probably benign |
Het |
| Or8b55 |
A |
T |
9: 38,726,871 (GRCm39) |
H24L |
probably benign |
Het |
| Pcnx1 |
T |
C |
12: 82,030,258 (GRCm39) |
V1711A |
probably benign |
Het |
| Pik3c3 |
A |
G |
18: 30,410,063 (GRCm39) |
D99G |
probably damaging |
Het |
| Pinx1 |
C |
A |
14: 64,157,024 (GRCm39) |
T317K |
probably benign |
Het |
| Ppargc1b |
G |
T |
18: 61,431,857 (GRCm39) |
|
probably null |
Het |
| Pradc1 |
T |
A |
6: 85,424,203 (GRCm39) |
I119F |
possibly damaging |
Het |
| Psat1 |
G |
T |
19: 15,892,243 (GRCm39) |
T242K |
probably damaging |
Het |
| Psma6 |
G |
A |
12: 55,454,317 (GRCm39) |
C28Y |
probably damaging |
Het |
| Pyurf |
A |
T |
6: 57,668,817 (GRCm39) |
C58* |
probably null |
Het |
| Rab3gap2 |
C |
A |
1: 185,016,081 (GRCm39) |
A1331E |
probably benign |
Het |
| Rnase4 |
T |
C |
14: 51,342,722 (GRCm39) |
*149Q |
probably null |
Het |
| Ruvbl2 |
T |
C |
7: 45,074,586 (GRCm39) |
K184R |
probably benign |
Het |
| Scn7a |
T |
G |
2: 66,510,527 (GRCm39) |
M1292L |
probably benign |
Het |
| Scn7a |
A |
T |
2: 66,531,231 (GRCm39) |
Y549N |
probably damaging |
Het |
| Selp |
A |
G |
1: 163,959,854 (GRCm39) |
D370G |
possibly damaging |
Het |
| Slc22a15 |
G |
A |
3: 101,767,769 (GRCm39) |
Q386* |
probably null |
Het |
| Slc22a29 |
A |
G |
19: 8,195,126 (GRCm39) |
|
probably null |
Het |
| Slc26a7 |
A |
C |
4: 14,548,491 (GRCm39) |
I266S |
possibly damaging |
Het |
| Smpd4 |
T |
C |
16: 17,443,872 (GRCm39) |
S112P |
probably damaging |
Het |
| Smpd4 |
T |
A |
16: 17,458,744 (GRCm39) |
L165Q |
probably damaging |
Het |
| Snx33 |
A |
G |
9: 56,833,982 (GRCm39) |
I29T |
probably benign |
Het |
| Spen |
G |
A |
4: 141,203,686 (GRCm39) |
P1647L |
unknown |
Het |
| Strip2 |
T |
C |
6: 29,941,940 (GRCm39) |
|
probably null |
Het |
| Swsap1 |
C |
T |
9: 21,867,280 (GRCm39) |
R75* |
probably null |
Het |
| Tesl1 |
A |
G |
X: 23,772,990 (GRCm39) |
I164V |
probably benign |
Het |
| Tmem210 |
C |
T |
2: 25,178,435 (GRCm39) |
T32I |
probably damaging |
Het |
| Tnn |
C |
T |
1: 159,975,154 (GRCm39) |
R91H |
possibly damaging |
Het |
| Tnni1 |
G |
A |
1: 135,736,420 (GRCm39) |
R94H |
probably damaging |
Het |
| Tnrc6c |
T |
A |
11: 117,651,556 (GRCm39) |
V1693D |
probably benign |
Het |
| Trip4 |
G |
A |
9: 65,782,259 (GRCm39) |
Q158* |
probably null |
Het |
| Ttc39b |
T |
C |
4: 83,155,586 (GRCm39) |
E474G |
probably damaging |
Het |
| Usp50 |
C |
A |
2: 126,617,782 (GRCm39) |
C221F |
probably damaging |
Het |
| Vmn1r171 |
T |
C |
7: 23,331,781 (GRCm39) |
I2T |
probably benign |
Het |
| Wdr62 |
T |
A |
7: 29,967,328 (GRCm39) |
I309F |
probably damaging |
Het |
| Xdh |
A |
T |
17: 74,217,204 (GRCm39) |
V688E |
probably damaging |
Het |
| Zfyve26 |
A |
G |
12: 79,285,718 (GRCm39) |
L2353P |
probably damaging |
Het |
| Zgpat |
C |
A |
2: 181,020,633 (GRCm39) |
R269S |
probably damaging |
Het |
|
| Other mutations in Myom2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00422:Myom2
|
APN |
8 |
15,119,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00426:Myom2
|
APN |
8 |
15,119,502 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00503:Myom2
|
APN |
8 |
15,164,289 (GRCm39) |
splice site |
probably null |
|
|
IGL01515:Myom2
|
APN |
8 |
15,172,655 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01649:Myom2
|
APN |
8 |
15,163,755 (GRCm39) |
missense |
probably benign |
0.24 |
|
IGL01658:Myom2
|
APN |
8 |
15,127,880 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Myom2
|
APN |
8 |
15,156,330 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01924:Myom2
|
APN |
8 |
15,119,685 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL01929:Myom2
|
APN |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02016:Myom2
|
APN |
8 |
15,175,195 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02511:Myom2
|
APN |
8 |
15,115,743 (GRCm39) |
missense |
probably benign |
|
|
IGL02558:Myom2
|
APN |
8 |
15,164,237 (GRCm39) |
missense |
probably benign |
0.31 |
|
IGL02944:Myom2
|
APN |
8 |
15,154,065 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03052:Myom2
|
APN |
8 |
15,173,442 (GRCm39) |
splice site |
probably benign |
|
|
IGL03195:Myom2
|
APN |
8 |
15,161,844 (GRCm39) |
nonsense |
probably null |
|
|
IGL03288:Myom2
|
APN |
8 |
15,172,679 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03402:Myom2
|
APN |
8 |
15,115,731 (GRCm39) |
missense |
probably benign |
|
|
yomama
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
yoyoma
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0069:Myom2
|
UTSW |
8 |
15,167,624 (GRCm39) |
missense |
probably benign |
|
|
R0116:Myom2
|
UTSW |
8 |
15,167,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0131:Myom2
|
UTSW |
8 |
15,133,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0373:Myom2
|
UTSW |
8 |
15,148,419 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0463:Myom2
|
UTSW |
8 |
15,154,123 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0544:Myom2
|
UTSW |
8 |
15,119,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0629:Myom2
|
UTSW |
8 |
15,119,783 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0634:Myom2
|
UTSW |
8 |
15,169,216 (GRCm39) |
splice site |
probably benign |
|
|
R0645:Myom2
|
UTSW |
8 |
15,167,698 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0730:Myom2
|
UTSW |
8 |
15,149,326 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0744:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R0836:Myom2
|
UTSW |
8 |
15,182,924 (GRCm39) |
nonsense |
probably null |
|
|
R1033:Myom2
|
UTSW |
8 |
15,158,934 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1103:Myom2
|
UTSW |
8 |
15,160,827 (GRCm39) |
missense |
probably benign |
0.22 |
|
R1110:Myom2
|
UTSW |
8 |
15,172,413 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1208:Myom2
|
UTSW |
8 |
15,134,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1353:Myom2
|
UTSW |
8 |
15,156,424 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1530:Myom2
|
UTSW |
8 |
15,172,384 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1544:Myom2
|
UTSW |
8 |
15,154,059 (GRCm39) |
splice site |
probably benign |
|
|
R1576:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1884:Myom2
|
UTSW |
8 |
15,164,278 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1908:Myom2
|
UTSW |
8 |
15,131,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1962:Myom2
|
UTSW |
8 |
15,182,599 (GRCm39) |
splice site |
probably null |
|
|
R1977:Myom2
|
UTSW |
8 |
15,135,263 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R2018:Myom2
|
UTSW |
8 |
15,181,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2049:Myom2
|
UTSW |
8 |
15,156,379 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2155:Myom2
|
UTSW |
8 |
15,134,555 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2314:Myom2
|
UTSW |
8 |
15,113,927 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2350:Myom2
|
UTSW |
8 |
15,158,835 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2358:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R2904:Myom2
|
UTSW |
8 |
15,148,348 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3418:Myom2
|
UTSW |
8 |
15,135,294 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3606:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3607:Myom2
|
UTSW |
8 |
15,119,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3735:Myom2
|
UTSW |
8 |
15,119,676 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3756:Myom2
|
UTSW |
8 |
15,152,650 (GRCm39) |
missense |
probably benign |
0.11 |
|
R3902:Myom2
|
UTSW |
8 |
15,154,165 (GRCm39) |
missense |
probably benign |
|
|
R3951:Myom2
|
UTSW |
8 |
15,134,556 (GRCm39) |
missense |
probably benign |
0.35 |
|
R4240:Myom2
|
UTSW |
8 |
15,182,895 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4361:Myom2
|
UTSW |
8 |
15,162,018 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4581:Myom2
|
UTSW |
8 |
15,156,459 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4736:Myom2
|
UTSW |
8 |
15,131,271 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5010:Myom2
|
UTSW |
8 |
15,133,310 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5108:Myom2
|
UTSW |
8 |
15,182,667 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5370:Myom2
|
UTSW |
8 |
15,149,343 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5427:Myom2
|
UTSW |
8 |
15,163,764 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5498:Myom2
|
UTSW |
8 |
15,179,142 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5504:Myom2
|
UTSW |
8 |
15,178,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5567:Myom2
|
UTSW |
8 |
15,152,546 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5743:Myom2
|
UTSW |
8 |
15,130,914 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5745:Myom2
|
UTSW |
8 |
15,172,705 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5844:Myom2
|
UTSW |
8 |
15,181,182 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5854:Myom2
|
UTSW |
8 |
15,158,478 (GRCm39) |
missense |
probably benign |
|
|
R6141:Myom2
|
UTSW |
8 |
15,113,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6209:Myom2
|
UTSW |
8 |
15,154,173 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R6248:Myom2
|
UTSW |
8 |
15,148,472 (GRCm39) |
splice site |
probably null |
|
|
R6378:Myom2
|
UTSW |
8 |
15,149,356 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6829:Myom2
|
UTSW |
8 |
15,172,643 (GRCm39) |
nonsense |
probably null |
|
|
R6913:Myom2
|
UTSW |
8 |
15,115,710 (GRCm39) |
missense |
probably benign |
|
|
R6957:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6958:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6960:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6961:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6962:Myom2
|
UTSW |
8 |
15,167,741 (GRCm39) |
missense |
probably null |
0.42 |
|
R6999:Myom2
|
UTSW |
8 |
15,134,531 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7148:Myom2
|
UTSW |
8 |
15,134,577 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7210:Myom2
|
UTSW |
8 |
15,154,114 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7298:Myom2
|
UTSW |
8 |
15,148,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7463:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably null |
0.94 |
|
R7535:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7573:Myom2
|
UTSW |
8 |
15,172,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7590:Myom2
|
UTSW |
8 |
15,167,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7690:Myom2
|
UTSW |
8 |
15,161,717 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7794:Myom2
|
UTSW |
8 |
15,133,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7822:Myom2
|
UTSW |
8 |
15,158,454 (GRCm39) |
missense |
probably benign |
|
|
R7948:Myom2
|
UTSW |
8 |
15,135,306 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8094:Myom2
|
UTSW |
8 |
15,119,418 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8268:Myom2
|
UTSW |
8 |
15,179,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8292:Myom2
|
UTSW |
8 |
15,182,888 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8514:Myom2
|
UTSW |
8 |
15,175,153 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R8539:Myom2
|
UTSW |
8 |
15,164,254 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8790:Myom2
|
UTSW |
8 |
15,169,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8824:Myom2
|
UTSW |
8 |
15,164,169 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8895:Myom2
|
UTSW |
8 |
15,152,589 (GRCm39) |
nonsense |
probably null |
|
|
R9024:Myom2
|
UTSW |
8 |
15,113,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9129:Myom2
|
UTSW |
8 |
15,154,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9224:Myom2
|
UTSW |
8 |
15,178,804 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9237:Myom2
|
UTSW |
8 |
15,152,591 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9321:Myom2
|
UTSW |
8 |
15,172,464 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9341:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9343:Myom2
|
UTSW |
8 |
15,134,633 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9375:Myom2
|
UTSW |
8 |
15,149,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9455:Myom2
|
UTSW |
8 |
15,156,293 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9563:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
R9565:Myom2
|
UTSW |
8 |
15,158,399 (GRCm39) |
nonsense |
probably null |
|
|
RF001:Myom2
|
UTSW |
8 |
15,131,418 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAATGTGTGTACCTCAGGGAGGGC -3'
(R):5'- TGGGAGAGCAGGAGCATTCAACTC -3'
Sequencing Primer
(F):5'- CTTGGGTGTATAGAAAGGAAGCATTG -3'
(R):5'- TGGTTATCAGCAAGCCCTG -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation