Incidental Mutation 'R4027:Ahdc1'
| ID |
313023 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ahdc1
|
| Ensembl Gene |
ENSMUSG00000037692 |
| Gene Name |
AT hook, DNA binding motif, containing 1 |
| Synonyms |
D030015G18Rik |
| MMRRC Submission |
040850-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.189)
|
| Stock # |
R4027 (G1)
|
| Quality Score |
196 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
132738797-132805421 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 132791476 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Proline
at position 906
(S906P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101536
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000044521]
[ENSMUST00000105914]
[ENSMUST00000105915]
[ENSMUST00000105916]
|
| AlphaFold |
Q6PAL7 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000044521
AA Change: S906P
PolyPhen 2
Score 0.734 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000047113
Gene: ENSMUSG00000037692
AA Change: S906P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
48 |
N/A |
INTRINSIC |
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
259 |
279 |
N/A |
INTRINSIC |
|
low complexity region
|
284 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
341 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
379 |
N/A |
INTRINSIC |
|
AT_hook
|
395 |
407 |
2.04e2 |
SMART |
|
low complexity region
|
418 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
508 |
N/A |
INTRINSIC |
|
AT_hook
|
541 |
553 |
5.47e-1 |
SMART |
|
low complexity region
|
661 |
685 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
785 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
820 |
N/A |
INTRINSIC |
|
low complexity region
|
836 |
857 |
N/A |
INTRINSIC |
|
low complexity region
|
963 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
1003 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1072 |
1084 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1251 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1271 |
N/A |
INTRINSIC |
|
low complexity region
|
1422 |
1436 |
N/A |
INTRINSIC |
|
low complexity region
|
1513 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1579 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000105914
AA Change: S906P
PolyPhen 2
Score 0.734 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000101534
Gene: ENSMUSG00000037692
AA Change: S906P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
48 |
N/A |
INTRINSIC |
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
259 |
279 |
N/A |
INTRINSIC |
|
low complexity region
|
284 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
341 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
379 |
N/A |
INTRINSIC |
|
AT_hook
|
395 |
407 |
2.04e2 |
SMART |
|
low complexity region
|
418 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
508 |
N/A |
INTRINSIC |
|
AT_hook
|
541 |
553 |
5.47e-1 |
SMART |
|
Pfam:DUF4683
|
559 |
639 |
6.4e-15 |
PFAM |
|
low complexity region
|
661 |
685 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
785 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
820 |
N/A |
INTRINSIC |
|
low complexity region
|
836 |
857 |
N/A |
INTRINSIC |
|
low complexity region
|
963 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
1003 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1072 |
1084 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1251 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1271 |
N/A |
INTRINSIC |
|
low complexity region
|
1422 |
1436 |
N/A |
INTRINSIC |
|
low complexity region
|
1513 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1579 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000105915
AA Change: S906P
PolyPhen 2
Score 0.734 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000101535
Gene: ENSMUSG00000037692
AA Change: S906P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
48 |
N/A |
INTRINSIC |
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
259 |
279 |
N/A |
INTRINSIC |
|
low complexity region
|
284 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
341 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
379 |
N/A |
INTRINSIC |
|
AT_hook
|
395 |
407 |
2.04e2 |
SMART |
|
low complexity region
|
418 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
508 |
N/A |
INTRINSIC |
|
AT_hook
|
541 |
553 |
5.47e-1 |
SMART |
|
low complexity region
|
661 |
685 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
785 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
820 |
N/A |
INTRINSIC |
|
low complexity region
|
836 |
857 |
N/A |
INTRINSIC |
|
low complexity region
|
963 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
1003 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1072 |
1084 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1251 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1271 |
N/A |
INTRINSIC |
|
low complexity region
|
1422 |
1436 |
N/A |
INTRINSIC |
|
low complexity region
|
1513 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1579 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000105916
AA Change: S906P
PolyPhen 2
Score 0.734 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000101536
Gene: ENSMUSG00000037692
AA Change: S906P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
48 |
N/A |
INTRINSIC |
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
259 |
279 |
N/A |
INTRINSIC |
|
low complexity region
|
284 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
341 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
379 |
N/A |
INTRINSIC |
|
AT_hook
|
395 |
407 |
2.04e2 |
SMART |
|
low complexity region
|
418 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
508 |
N/A |
INTRINSIC |
|
AT_hook
|
541 |
553 |
5.47e-1 |
SMART |
|
low complexity region
|
661 |
685 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
785 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
820 |
N/A |
INTRINSIC |
|
low complexity region
|
836 |
857 |
N/A |
INTRINSIC |
|
low complexity region
|
963 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
1003 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1072 |
1084 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1251 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1271 |
N/A |
INTRINSIC |
|
low complexity region
|
1422 |
1436 |
N/A |
INTRINSIC |
|
low complexity region
|
1513 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1579 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135548
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142524
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000148518
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154482
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156677
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154646
|
| Meta Mutation Damage Score |
0.0732 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 97.0%
- 20x: 94.2%
|
| Validation Efficiency |
97% (60/62) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing two AT-hooks, which likely function in DNA binding. Mutations in this gene were found in individuals with Xia-Gibbs syndrome. [provided by RefSeq, Jun 2014]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 58 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930402F06Rik |
A |
G |
2: 35,270,408 (GRCm39) |
F98L |
probably damaging |
Het |
| Adam26b |
T |
C |
8: 43,973,409 (GRCm39) |
N531S |
probably benign |
Het |
| Ank |
A |
G |
15: 27,544,343 (GRCm39) |
N35D |
probably damaging |
Het |
| Ano10 |
A |
G |
9: 122,081,994 (GRCm39) |
|
probably benign |
Het |
| Atp4a |
T |
C |
7: 30,424,377 (GRCm39) |
|
probably null |
Het |
| C030005K15Rik |
T |
C |
10: 97,561,404 (GRCm39) |
Y109C |
unknown |
Het |
| Carmil1 |
T |
A |
13: 24,251,206 (GRCm39) |
|
probably benign |
Het |
| Ccl2 |
A |
G |
11: 81,927,885 (GRCm39) |
R110G |
probably benign |
Het |
| Cntnap2 |
C |
A |
6: 46,833,062 (GRCm39) |
F758L |
probably benign |
Het |
| Cog6 |
A |
C |
3: 52,909,950 (GRCm39) |
D267E |
possibly damaging |
Het |
| Cyp4f37 |
G |
T |
17: 32,850,646 (GRCm39) |
E366D |
probably benign |
Het |
| Dcun1d4 |
A |
G |
5: 73,691,980 (GRCm39) |
D89G |
probably damaging |
Het |
| Dpep1 |
T |
C |
8: 123,920,892 (GRCm39) |
V24A |
probably benign |
Het |
| Eefsec |
T |
C |
6: 88,353,232 (GRCm39) |
I48V |
probably benign |
Het |
| Elmo2 |
G |
A |
2: 165,136,169 (GRCm39) |
Q195* |
probably null |
Het |
| Ephb3 |
A |
G |
16: 21,040,447 (GRCm39) |
D561G |
probably damaging |
Het |
| Erich2 |
C |
A |
2: 70,343,134 (GRCm39) |
|
probably benign |
Het |
| Gatm |
A |
G |
2: 122,427,927 (GRCm39) |
V362A |
probably damaging |
Het |
| Gdf10 |
A |
G |
14: 33,654,572 (GRCm39) |
M360V |
probably damaging |
Het |
| Gpr141 |
T |
C |
13: 19,935,995 (GRCm39) |
N260S |
probably benign |
Het |
| Hectd1 |
T |
A |
12: 51,849,219 (GRCm39) |
|
probably null |
Het |
| Insrr |
A |
G |
3: 87,716,906 (GRCm39) |
E682G |
probably benign |
Het |
| Itgax |
A |
G |
7: 127,740,438 (GRCm39) |
I742V |
possibly damaging |
Het |
| Kcnh1 |
T |
C |
1: 191,959,007 (GRCm39) |
V187A |
probably benign |
Het |
| Kdm6b |
G |
T |
11: 69,297,094 (GRCm39) |
S419R |
possibly damaging |
Het |
| Kmt2a |
A |
T |
9: 44,747,990 (GRCm39) |
|
probably benign |
Het |
| Krt10 |
A |
G |
11: 99,277,019 (GRCm39) |
|
probably benign |
Het |
| Lct |
G |
A |
1: 128,212,918 (GRCm39) |
R1912C |
probably benign |
Het |
| Lefty1 |
T |
C |
1: 180,765,346 (GRCm39) |
S305P |
probably benign |
Het |
| Mast3 |
A |
G |
8: 71,240,552 (GRCm39) |
L279P |
probably damaging |
Het |
| Mfsd4b3-ps |
T |
C |
10: 39,823,343 (GRCm39) |
T306A |
probably benign |
Het |
| Mgam |
G |
A |
6: 40,731,836 (GRCm39) |
R1351Q |
probably damaging |
Het |
| Mknk1 |
T |
A |
4: 115,721,758 (GRCm39) |
F101I |
probably damaging |
Het |
| Mlc1 |
T |
C |
15: 88,850,697 (GRCm39) |
I154V |
probably benign |
Het |
| Myo5b |
T |
C |
18: 74,892,311 (GRCm39) |
I1685T |
possibly damaging |
Het |
| Nacc2 |
T |
A |
2: 25,950,348 (GRCm39) |
M463L |
probably benign |
Het |
| Nek11 |
A |
C |
9: 105,121,589 (GRCm39) |
Y443* |
probably null |
Het |
| Nme4 |
T |
C |
17: 26,313,196 (GRCm39) |
|
probably null |
Het |
| Nova1 |
A |
G |
12: 46,863,801 (GRCm39) |
|
probably benign |
Het |
| Or52h9 |
A |
T |
7: 104,202,530 (GRCm39) |
I135F |
possibly damaging |
Het |
| Parp10 |
A |
G |
15: 76,125,354 (GRCm39) |
|
probably null |
Het |
| Pkd1l3 |
T |
A |
8: 110,350,603 (GRCm39) |
S483T |
possibly damaging |
Het |
| Plce1 |
T |
C |
19: 38,512,709 (GRCm39) |
S3P |
probably damaging |
Het |
| Pnldc1 |
T |
C |
17: 13,109,666 (GRCm39) |
D400G |
probably benign |
Het |
| Polr2b |
G |
A |
5: 77,496,252 (GRCm39) |
R1141H |
possibly damaging |
Het |
| Prmt6 |
A |
G |
3: 110,157,257 (GRCm39) |
I344T |
probably damaging |
Het |
| Psmd2 |
G |
A |
16: 20,481,955 (GRCm39) |
G896D |
probably damaging |
Het |
| Ranbp17 |
C |
T |
11: 33,450,718 (GRCm39) |
R73Q |
possibly damaging |
Het |
| Rcn1 |
G |
T |
2: 105,229,395 (GRCm39) |
Y52* |
probably null |
Het |
| Reck |
T |
C |
4: 43,922,931 (GRCm39) |
I402T |
probably damaging |
Het |
| Tecpr1 |
C |
A |
5: 144,143,077 (GRCm39) |
A735S |
probably benign |
Het |
| Tshz1 |
T |
C |
18: 84,032,954 (GRCm39) |
K485E |
possibly damaging |
Het |
| Ube4a |
G |
A |
9: 44,861,198 (GRCm39) |
|
probably benign |
Het |
| Vldlr |
A |
G |
19: 27,215,713 (GRCm39) |
T237A |
probably benign |
Het |
| Vmn1r74 |
C |
A |
7: 11,580,898 (GRCm39) |
T66K |
probably damaging |
Het |
| Wdr49 |
C |
A |
3: 75,230,972 (GRCm39) |
L563F |
probably benign |
Het |
| Zmym1 |
C |
T |
4: 126,943,672 (GRCm39) |
V239I |
probably benign |
Het |
| Zmym5 |
T |
A |
14: 57,035,268 (GRCm39) |
T267S |
probably benign |
Het |
|
| Other mutations in Ahdc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00946:Ahdc1
|
APN |
4 |
132,790,373 (GRCm39) |
missense |
probably benign |
0.33 |
|
IGL02293:Ahdc1
|
APN |
4 |
132,792,929 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02338:Ahdc1
|
APN |
4 |
132,789,860 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL02828:Ahdc1
|
APN |
4 |
132,790,232 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL02859:Ahdc1
|
APN |
4 |
132,790,004 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02859:Ahdc1
|
APN |
4 |
132,790,003 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
IGL02901:Ahdc1
|
APN |
4 |
132,792,245 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL03323:Ahdc1
|
APN |
4 |
132,792,739 (GRCm39) |
missense |
probably benign |
|
|
FR4304:Ahdc1
|
UTSW |
4 |
132,790,070 (GRCm39) |
small insertion |
probably benign |
|
|
FR4548:Ahdc1
|
UTSW |
4 |
132,790,071 (GRCm39) |
small insertion |
probably benign |
|
|
FR4548:Ahdc1
|
UTSW |
4 |
132,790,068 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Ahdc1
|
UTSW |
4 |
132,790,070 (GRCm39) |
small insertion |
probably benign |
|
|
R0325:Ahdc1
|
UTSW |
4 |
132,790,030 (GRCm39) |
missense |
unknown |
|
|
R0550:Ahdc1
|
UTSW |
4 |
132,790,348 (GRCm39) |
missense |
probably benign |
0.33 |
|
R0681:Ahdc1
|
UTSW |
4 |
132,792,827 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0683:Ahdc1
|
UTSW |
4 |
132,792,827 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0731:Ahdc1
|
UTSW |
4 |
132,790,262 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0751:Ahdc1
|
UTSW |
4 |
132,792,707 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1137:Ahdc1
|
UTSW |
4 |
132,789,424 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1184:Ahdc1
|
UTSW |
4 |
132,792,707 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1331:Ahdc1
|
UTSW |
4 |
132,791,002 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1599:Ahdc1
|
UTSW |
4 |
132,792,247 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2202:Ahdc1
|
UTSW |
4 |
132,793,220 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2205:Ahdc1
|
UTSW |
4 |
132,793,220 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2261:Ahdc1
|
UTSW |
4 |
132,790,474 (GRCm39) |
missense |
unknown |
|
|
R2262:Ahdc1
|
UTSW |
4 |
132,790,474 (GRCm39) |
missense |
unknown |
|
|
R3683:Ahdc1
|
UTSW |
4 |
132,793,013 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R3684:Ahdc1
|
UTSW |
4 |
132,793,013 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R3685:Ahdc1
|
UTSW |
4 |
132,793,013 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R3713:Ahdc1
|
UTSW |
4 |
132,793,297 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4807:Ahdc1
|
UTSW |
4 |
132,791,624 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4987:Ahdc1
|
UTSW |
4 |
132,791,631 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5126:Ahdc1
|
UTSW |
4 |
132,790,833 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5276:Ahdc1
|
UTSW |
4 |
132,790,109 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5680:Ahdc1
|
UTSW |
4 |
132,792,907 (GRCm39) |
missense |
probably benign |
|
|
R5997:Ahdc1
|
UTSW |
4 |
132,791,206 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6050:Ahdc1
|
UTSW |
4 |
132,793,202 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6271:Ahdc1
|
UTSW |
4 |
132,792,035 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R6410:Ahdc1
|
UTSW |
4 |
132,790,210 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6519:Ahdc1
|
UTSW |
4 |
132,792,079 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6970:Ahdc1
|
UTSW |
4 |
132,789,656 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7199:Ahdc1
|
UTSW |
4 |
132,791,935 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7202:Ahdc1
|
UTSW |
4 |
132,789,198 (GRCm39) |
nonsense |
probably null |
|
|
R7576:Ahdc1
|
UTSW |
4 |
132,792,313 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7614:Ahdc1
|
UTSW |
4 |
132,790,825 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7794:Ahdc1
|
UTSW |
4 |
132,791,289 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R7875:Ahdc1
|
UTSW |
4 |
132,791,161 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8016:Ahdc1
|
UTSW |
4 |
132,790,226 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R8295:Ahdc1
|
UTSW |
4 |
132,788,762 (GRCm39) |
start codon destroyed |
probably null |
0.53 |
|
R8332:Ahdc1
|
UTSW |
4 |
132,791,282 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8719:Ahdc1
|
UTSW |
4 |
132,791,533 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8725:Ahdc1
|
UTSW |
4 |
132,792,743 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8862:Ahdc1
|
UTSW |
4 |
132,791,129 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9158:Ahdc1
|
UTSW |
4 |
132,792,505 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9179:Ahdc1
|
UTSW |
4 |
132,788,929 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9362:Ahdc1
|
UTSW |
4 |
132,790,348 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9428:Ahdc1
|
UTSW |
4 |
132,791,773 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
RF017:Ahdc1
|
UTSW |
4 |
132,790,062 (GRCm39) |
small insertion |
probably benign |
|
|
RF020:Ahdc1
|
UTSW |
4 |
132,791,588 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
T0722:Ahdc1
|
UTSW |
4 |
132,790,065 (GRCm39) |
small insertion |
probably benign |
|
|
T0975:Ahdc1
|
UTSW |
4 |
132,790,065 (GRCm39) |
small insertion |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCCCTGCTTGATTCAGATGAC -3'
(R):5'- CATAGCCACCATACTGAGGTG -3'
Sequencing Primer
(F):5'- GATTCAGATGACTCCTCTGACC -3'
(R):5'- CCACCATACTGAGGTGGGTAG -3'
|
| Posted On |
2015-04-30 |
Incidental Mutation