Incidental Mutation 'R3713:Ahdc1'
| ID |
259722 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ahdc1
|
| Ensembl Gene |
ENSMUSG00000037692 |
| Gene Name |
AT hook, DNA binding motif, containing 1 |
| Synonyms |
D030015G18Rik |
| MMRRC Submission |
040706-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.189)
|
| Stock # |
R3713 (G1)
|
| Quality Score |
217 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
132738797-132805421 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 132793297 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Threonine
at position 1513
(A1513T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000101536
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000044521]
[ENSMUST00000105914]
[ENSMUST00000105915]
[ENSMUST00000105916]
|
| AlphaFold |
Q6PAL7 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000044521
AA Change: A1513T
PolyPhen 2
Score 0.845 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000047113
Gene: ENSMUSG00000037692
AA Change: A1513T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
48 |
N/A |
INTRINSIC |
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
259 |
279 |
N/A |
INTRINSIC |
|
low complexity region
|
284 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
341 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
379 |
N/A |
INTRINSIC |
|
AT_hook
|
395 |
407 |
2.04e2 |
SMART |
|
low complexity region
|
418 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
508 |
N/A |
INTRINSIC |
|
AT_hook
|
541 |
553 |
5.47e-1 |
SMART |
|
low complexity region
|
661 |
685 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
785 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
820 |
N/A |
INTRINSIC |
|
low complexity region
|
836 |
857 |
N/A |
INTRINSIC |
|
low complexity region
|
963 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
1003 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1072 |
1084 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1251 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1271 |
N/A |
INTRINSIC |
|
low complexity region
|
1422 |
1436 |
N/A |
INTRINSIC |
|
low complexity region
|
1513 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1579 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000105914
AA Change: A1513T
PolyPhen 2
Score 0.845 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000101534
Gene: ENSMUSG00000037692
AA Change: A1513T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
48 |
N/A |
INTRINSIC |
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
259 |
279 |
N/A |
INTRINSIC |
|
low complexity region
|
284 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
341 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
379 |
N/A |
INTRINSIC |
|
AT_hook
|
395 |
407 |
2.04e2 |
SMART |
|
low complexity region
|
418 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
508 |
N/A |
INTRINSIC |
|
AT_hook
|
541 |
553 |
5.47e-1 |
SMART |
|
Pfam:DUF4683
|
559 |
639 |
6.4e-15 |
PFAM |
|
low complexity region
|
661 |
685 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
785 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
820 |
N/A |
INTRINSIC |
|
low complexity region
|
836 |
857 |
N/A |
INTRINSIC |
|
low complexity region
|
963 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
1003 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1072 |
1084 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1251 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1271 |
N/A |
INTRINSIC |
|
low complexity region
|
1422 |
1436 |
N/A |
INTRINSIC |
|
low complexity region
|
1513 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1579 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000105915
AA Change: A1513T
PolyPhen 2
Score 0.845 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000101535
Gene: ENSMUSG00000037692
AA Change: A1513T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
48 |
N/A |
INTRINSIC |
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
259 |
279 |
N/A |
INTRINSIC |
|
low complexity region
|
284 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
341 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
379 |
N/A |
INTRINSIC |
|
AT_hook
|
395 |
407 |
2.04e2 |
SMART |
|
low complexity region
|
418 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
508 |
N/A |
INTRINSIC |
|
AT_hook
|
541 |
553 |
5.47e-1 |
SMART |
|
low complexity region
|
661 |
685 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
785 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
820 |
N/A |
INTRINSIC |
|
low complexity region
|
836 |
857 |
N/A |
INTRINSIC |
|
low complexity region
|
963 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
1003 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1072 |
1084 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1251 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1271 |
N/A |
INTRINSIC |
|
low complexity region
|
1422 |
1436 |
N/A |
INTRINSIC |
|
low complexity region
|
1513 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1579 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000105916
AA Change: A1513T
PolyPhen 2
Score 0.845 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000101536
Gene: ENSMUSG00000037692
AA Change: A1513T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
25 |
48 |
N/A |
INTRINSIC |
|
low complexity region
|
61 |
75 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
234 |
N/A |
INTRINSIC |
|
low complexity region
|
259 |
279 |
N/A |
INTRINSIC |
|
low complexity region
|
284 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
327 |
341 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
379 |
N/A |
INTRINSIC |
|
AT_hook
|
395 |
407 |
2.04e2 |
SMART |
|
low complexity region
|
418 |
446 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
508 |
N/A |
INTRINSIC |
|
AT_hook
|
541 |
553 |
5.47e-1 |
SMART |
|
low complexity region
|
661 |
685 |
N/A |
INTRINSIC |
|
low complexity region
|
696 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
770 |
785 |
N/A |
INTRINSIC |
|
low complexity region
|
805 |
820 |
N/A |
INTRINSIC |
|
low complexity region
|
836 |
857 |
N/A |
INTRINSIC |
|
low complexity region
|
963 |
974 |
N/A |
INTRINSIC |
|
low complexity region
|
1003 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1072 |
1084 |
N/A |
INTRINSIC |
|
low complexity region
|
1153 |
1168 |
N/A |
INTRINSIC |
|
low complexity region
|
1180 |
1197 |
N/A |
INTRINSIC |
|
low complexity region
|
1243 |
1251 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1271 |
N/A |
INTRINSIC |
|
low complexity region
|
1422 |
1436 |
N/A |
INTRINSIC |
|
low complexity region
|
1513 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1566 |
1579 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135548
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142524
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000148518
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156677
|
| Meta Mutation Damage Score |
0.0789 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 97.0%
- 20x: 94.0%
|
| Validation Efficiency |
100% (67/67) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing two AT-hooks, which likely function in DNA binding. Mutations in this gene were found in individuals with Xia-Gibbs syndrome. [provided by RefSeq, Jun 2014]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 70 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310079G19Rik |
T |
C |
16: 88,424,081 (GRCm39) |
M137V |
probably benign |
Het |
| Aak1 |
T |
A |
6: 86,932,172 (GRCm39) |
I381N |
probably benign |
Het |
| Abcd4 |
C |
T |
12: 84,658,533 (GRCm39) |
M223I |
probably benign |
Het |
| Adgrf2 |
A |
G |
17: 43,023,979 (GRCm39) |
V164A |
probably damaging |
Het |
| Akap13 |
T |
C |
7: 75,235,929 (GRCm39) |
M168T |
probably damaging |
Het |
| Aox1 |
C |
T |
1: 58,095,374 (GRCm39) |
T196I |
probably benign |
Het |
| Aqr |
A |
G |
2: 113,949,150 (GRCm39) |
|
probably benign |
Het |
| Astn1 |
A |
G |
1: 158,495,102 (GRCm39) |
E1042G |
possibly damaging |
Het |
| Azi2 |
A |
G |
9: 117,876,508 (GRCm39) |
D8G |
possibly damaging |
Het |
| Bcam |
T |
C |
7: 19,498,118 (GRCm39) |
T302A |
probably benign |
Het |
| Cct6b |
A |
T |
11: 82,651,183 (GRCm39) |
I110N |
probably damaging |
Het |
| Cd109 |
CATTTATTTATTTATTTATTTATTTATTTATTTAT |
CATTTATTTATTTATTTATTTATTTATTTATTTATTTAT |
9: 78,619,782 (GRCm39) |
|
probably benign |
Het |
| Ceacam5 |
G |
A |
7: 17,493,263 (GRCm39) |
S762N |
possibly damaging |
Het |
| Cecr2 |
T |
C |
6: 120,735,221 (GRCm39) |
L819P |
probably damaging |
Het |
| Cers3 |
G |
T |
7: 66,435,823 (GRCm39) |
A261S |
probably benign |
Het |
| Chd2 |
A |
G |
7: 73,121,538 (GRCm39) |
|
probably benign |
Het |
| Col7a1 |
G |
T |
9: 108,793,508 (GRCm39) |
G1357* |
probably null |
Het |
| Cux1 |
A |
G |
5: 136,594,397 (GRCm39) |
|
probably benign |
Het |
| Cwh43 |
A |
T |
5: 73,595,835 (GRCm39) |
I535F |
probably damaging |
Het |
| Dexi |
A |
T |
16: 10,360,553 (GRCm39) |
M1K |
probably null |
Het |
| Dnah12 |
T |
C |
14: 26,534,747 (GRCm39) |
V2081A |
probably benign |
Het |
| Efcab5 |
A |
T |
11: 77,007,008 (GRCm39) |
L872Q |
probably damaging |
Het |
| Enpp7 |
A |
G |
11: 118,881,344 (GRCm39) |
Y163C |
probably damaging |
Het |
| Fam221a |
T |
C |
6: 49,349,548 (GRCm39) |
Y38H |
probably damaging |
Het |
| Foxred1 |
A |
G |
9: 35,122,186 (GRCm39) |
M1T |
probably null |
Het |
| Fscn3 |
C |
T |
6: 28,428,091 (GRCm39) |
T26I |
possibly damaging |
Het |
| Galp |
A |
T |
7: 6,216,836 (GRCm39) |
D72V |
probably damaging |
Het |
| Gm9843 |
A |
G |
16: 76,200,419 (GRCm39) |
|
noncoding transcript |
Het |
| Grm7 |
G |
T |
6: 110,623,309 (GRCm39) |
V161F |
probably damaging |
Het |
| Lmbrd1 |
T |
C |
1: 24,732,076 (GRCm39) |
Y98H |
probably damaging |
Het |
| Lrrc63 |
T |
G |
14: 75,344,776 (GRCm39) |
Y437S |
probably benign |
Het |
| Macc1 |
A |
G |
12: 119,410,576 (GRCm39) |
E448G |
probably benign |
Het |
| Madcam1 |
A |
G |
10: 79,504,194 (GRCm39) |
H404R |
probably benign |
Het |
| Mink1 |
G |
T |
11: 70,499,776 (GRCm39) |
R773L |
possibly damaging |
Het |
| Mroh2b |
A |
G |
15: 4,973,131 (GRCm39) |
I1045V |
probably benign |
Het |
| Mroh3 |
T |
C |
1: 136,113,714 (GRCm39) |
T692A |
probably benign |
Het |
| Myo15a |
A |
T |
11: 60,370,057 (GRCm39) |
E939V |
possibly damaging |
Het |
| Naip2 |
A |
G |
13: 100,298,410 (GRCm39) |
F542S |
probably damaging |
Het |
| Napsa |
A |
G |
7: 44,230,852 (GRCm39) |
Y73C |
probably damaging |
Het |
| Ndst4 |
A |
T |
3: 125,355,154 (GRCm39) |
H354L |
possibly damaging |
Het |
| Neil1 |
A |
T |
9: 57,054,254 (GRCm39) |
V22E |
probably damaging |
Het |
| Nol4 |
T |
C |
18: 23,172,994 (GRCm39) |
I36V |
probably damaging |
Het |
| Nprl3 |
G |
A |
11: 32,205,464 (GRCm39) |
T111I |
probably damaging |
Het |
| Or12k8 |
A |
G |
2: 36,975,517 (GRCm39) |
M81T |
possibly damaging |
Het |
| Or1e26 |
A |
T |
11: 73,479,731 (GRCm39) |
Y278N |
probably damaging |
Het |
| Or4p22 |
C |
A |
2: 88,317,787 (GRCm39) |
T237N |
probably damaging |
Het |
| Pald1 |
G |
A |
10: 61,178,144 (GRCm39) |
T624I |
possibly damaging |
Het |
| Pcdhb13 |
C |
T |
18: 37,576,786 (GRCm39) |
P388L |
probably damaging |
Het |
| Pcdhga6 |
T |
C |
18: 37,840,976 (GRCm39) |
V232A |
probably damaging |
Het |
| Pde6b |
A |
G |
5: 108,570,928 (GRCm39) |
I388V |
probably damaging |
Het |
| Phactr2 |
C |
A |
10: 13,264,476 (GRCm39) |
|
probably benign |
Het |
| Prdx5 |
T |
C |
19: 6,885,477 (GRCm39) |
D56G |
probably damaging |
Het |
| Ptprh |
A |
T |
7: 4,574,969 (GRCm39) |
I350N |
probably damaging |
Het |
| Rangap1 |
C |
A |
15: 81,594,661 (GRCm39) |
E389D |
probably benign |
Het |
| Reln |
A |
G |
5: 22,109,732 (GRCm39) |
V3126A |
probably damaging |
Het |
| Rpl21 |
G |
A |
5: 146,771,847 (GRCm39) |
G59S |
possibly damaging |
Het |
| Rsph6a |
G |
A |
7: 18,791,475 (GRCm39) |
V215M |
probably damaging |
Het |
| Smcp |
T |
C |
3: 92,491,431 (GRCm39) |
K139E |
unknown |
Het |
| Stag1 |
A |
G |
9: 100,771,671 (GRCm39) |
T699A |
probably benign |
Het |
| Tars3 |
G |
A |
7: 65,338,700 (GRCm39) |
|
probably null |
Het |
| Tle1 |
G |
T |
4: 72,044,659 (GRCm39) |
H459Q |
possibly damaging |
Het |
| Ttn |
G |
A |
2: 76,561,363 (GRCm39) |
P27302S |
probably damaging |
Het |
| Ttn |
C |
T |
2: 76,571,610 (GRCm39) |
V26428I |
probably damaging |
Het |
| Usp53 |
T |
C |
3: 122,742,968 (GRCm39) |
E656G |
probably benign |
Het |
| Vmn1r218 |
A |
T |
13: 23,321,081 (GRCm39) |
N63Y |
probably damaging |
Het |
| Vmn1r79 |
A |
G |
7: 11,910,139 (GRCm39) |
N40S |
possibly damaging |
Het |
| Wdr35 |
A |
G |
12: 9,077,648 (GRCm39) |
D1107G |
possibly damaging |
Het |
| Zfp101 |
A |
G |
17: 33,600,880 (GRCm39) |
M292T |
probably benign |
Het |
| Zfp108 |
T |
A |
7: 23,961,270 (GRCm39) |
C620* |
probably null |
Het |
| Zscan4b |
T |
C |
7: 10,635,818 (GRCm39) |
T170A |
probably benign |
Het |
|
| Other mutations in Ahdc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00946:Ahdc1
|
APN |
4 |
132,790,373 (GRCm39) |
missense |
probably benign |
0.33 |
|
IGL02293:Ahdc1
|
APN |
4 |
132,792,929 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02338:Ahdc1
|
APN |
4 |
132,789,860 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
IGL02828:Ahdc1
|
APN |
4 |
132,790,232 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
IGL02859:Ahdc1
|
APN |
4 |
132,790,004 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02859:Ahdc1
|
APN |
4 |
132,790,003 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
IGL02901:Ahdc1
|
APN |
4 |
132,792,245 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL03323:Ahdc1
|
APN |
4 |
132,792,739 (GRCm39) |
missense |
probably benign |
|
|
FR4304:Ahdc1
|
UTSW |
4 |
132,790,070 (GRCm39) |
small insertion |
probably benign |
|
|
FR4548:Ahdc1
|
UTSW |
4 |
132,790,071 (GRCm39) |
small insertion |
probably benign |
|
|
FR4548:Ahdc1
|
UTSW |
4 |
132,790,068 (GRCm39) |
small insertion |
probably benign |
|
|
FR4737:Ahdc1
|
UTSW |
4 |
132,790,070 (GRCm39) |
small insertion |
probably benign |
|
|
R0325:Ahdc1
|
UTSW |
4 |
132,790,030 (GRCm39) |
missense |
unknown |
|
|
R0550:Ahdc1
|
UTSW |
4 |
132,790,348 (GRCm39) |
missense |
probably benign |
0.33 |
|
R0681:Ahdc1
|
UTSW |
4 |
132,792,827 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0683:Ahdc1
|
UTSW |
4 |
132,792,827 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0731:Ahdc1
|
UTSW |
4 |
132,790,262 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0751:Ahdc1
|
UTSW |
4 |
132,792,707 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1137:Ahdc1
|
UTSW |
4 |
132,789,424 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1184:Ahdc1
|
UTSW |
4 |
132,792,707 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1331:Ahdc1
|
UTSW |
4 |
132,791,002 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1599:Ahdc1
|
UTSW |
4 |
132,792,247 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2202:Ahdc1
|
UTSW |
4 |
132,793,220 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2205:Ahdc1
|
UTSW |
4 |
132,793,220 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R2261:Ahdc1
|
UTSW |
4 |
132,790,474 (GRCm39) |
missense |
unknown |
|
|
R2262:Ahdc1
|
UTSW |
4 |
132,790,474 (GRCm39) |
missense |
unknown |
|
|
R3683:Ahdc1
|
UTSW |
4 |
132,793,013 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R3684:Ahdc1
|
UTSW |
4 |
132,793,013 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R3685:Ahdc1
|
UTSW |
4 |
132,793,013 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R4027:Ahdc1
|
UTSW |
4 |
132,791,476 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4807:Ahdc1
|
UTSW |
4 |
132,791,624 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4987:Ahdc1
|
UTSW |
4 |
132,791,631 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5126:Ahdc1
|
UTSW |
4 |
132,790,833 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5276:Ahdc1
|
UTSW |
4 |
132,790,109 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5680:Ahdc1
|
UTSW |
4 |
132,792,907 (GRCm39) |
missense |
probably benign |
|
|
R5997:Ahdc1
|
UTSW |
4 |
132,791,206 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6050:Ahdc1
|
UTSW |
4 |
132,793,202 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6271:Ahdc1
|
UTSW |
4 |
132,792,035 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R6410:Ahdc1
|
UTSW |
4 |
132,790,210 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6519:Ahdc1
|
UTSW |
4 |
132,792,079 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6970:Ahdc1
|
UTSW |
4 |
132,789,656 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R7199:Ahdc1
|
UTSW |
4 |
132,791,935 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7202:Ahdc1
|
UTSW |
4 |
132,789,198 (GRCm39) |
nonsense |
probably null |
|
|
R7576:Ahdc1
|
UTSW |
4 |
132,792,313 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7614:Ahdc1
|
UTSW |
4 |
132,790,825 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7794:Ahdc1
|
UTSW |
4 |
132,791,289 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R7875:Ahdc1
|
UTSW |
4 |
132,791,161 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8016:Ahdc1
|
UTSW |
4 |
132,790,226 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R8295:Ahdc1
|
UTSW |
4 |
132,788,762 (GRCm39) |
start codon destroyed |
probably null |
0.53 |
|
R8332:Ahdc1
|
UTSW |
4 |
132,791,282 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8719:Ahdc1
|
UTSW |
4 |
132,791,533 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8725:Ahdc1
|
UTSW |
4 |
132,792,743 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8862:Ahdc1
|
UTSW |
4 |
132,791,129 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9158:Ahdc1
|
UTSW |
4 |
132,792,505 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9179:Ahdc1
|
UTSW |
4 |
132,788,929 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9362:Ahdc1
|
UTSW |
4 |
132,790,348 (GRCm39) |
missense |
probably benign |
0.33 |
|
R9428:Ahdc1
|
UTSW |
4 |
132,791,773 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
RF017:Ahdc1
|
UTSW |
4 |
132,790,062 (GRCm39) |
small insertion |
probably benign |
|
|
RF020:Ahdc1
|
UTSW |
4 |
132,791,588 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
T0722:Ahdc1
|
UTSW |
4 |
132,790,065 (GRCm39) |
small insertion |
probably benign |
|
|
T0975:Ahdc1
|
UTSW |
4 |
132,790,065 (GRCm39) |
small insertion |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGTTGCAAGGGTACAGCCTAC -3'
(R):5'- AAATGTGTCCTCAGGGTGAG -3'
Sequencing Primer
(F):5'- AGCCTACTGGTACCCACC -3'
(R):5'- AGGAAGCCACTCTTAGGGC -3'
|
| Posted On |
2015-01-23 |
Incidental Mutation