Mutagenetix > Incidental Mutation

Incidental Mutation 'R0255:Rusc2'

34645

Institutional Source

Beutler Lab

Gene Symbol

Rusc2

Ensembl Gene

ENSMUSG00000035969

Gene Name

RUN and SH3 domain containing 2

Synonyms

MMRRC Submission

038486-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.205) question?

Stock #

R0255 (G1)

Quality Score

212

Status

Validated

Chromosome

Chromosomal Location

43381979-43427088 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 43423954 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Alanine at position 1036 (V1036A)

Ref Sequence

ENSEMBL: ENSMUSP00000118528 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000035645] [ENSMUST00000052829] [ENSMUST00000098106] [ENSMUST00000107928] [ENSMUST00000107929] [ENSMUST00000131668] [ENSMUST00000149676] [ENSMUST00000173682] [ENSMUST00000171134] [ENSMUST00000149221]

AlphaFold

no structure available at present

Predicted Effect

possibly damaging
Transcript: ENSMUST00000035645
AA Change: V1036A

PolyPhen 2 Score 0.540 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000038379
Gene: ENSMUSG00000035969
AA Change: V1036A

Domain	Start	End	E-Value	Type
low complexity region	39	47	N/A	INTRINSIC
low complexity region	212	230	N/A	INTRINSIC
low complexity region	253	265	N/A	INTRINSIC
low complexity region	411	427	N/A	INTRINSIC
low complexity region	435	448	N/A	INTRINSIC
low complexity region	530	544	N/A	INTRINSIC
low complexity region	600	617	N/A	INTRINSIC
low complexity region	795	809	N/A	INTRINSIC
RUN	1109	1177	3.66e-21	SMART
low complexity region	1235	1260	N/A	INTRINSIC
low complexity region	1289	1324	N/A	INTRINSIC
low complexity region	1330	1341	N/A	INTRINSIC
SH3	1457	1512	7.4e-11	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000052829

SMART Domains

Protein: ENSMUSP00000058980
Gene: ENSMUSG00000042788

Domain	Start	End	E-Value	Type
Pfam:DUF2475	15	47	2.9e-12	PFAM

Predicted Effect

possibly damaging
Transcript: ENSMUST00000098106
AA Change: V1036A

PolyPhen 2 Score 0.540 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000095710
Gene: ENSMUSG00000035969
AA Change: V1036A

Domain	Start	End	E-Value	Type
low complexity region	39	47	N/A	INTRINSIC
low complexity region	212	230	N/A	INTRINSIC
low complexity region	253	265	N/A	INTRINSIC
low complexity region	411	427	N/A	INTRINSIC
low complexity region	435	448	N/A	INTRINSIC
low complexity region	530	544	N/A	INTRINSIC
low complexity region	600	617	N/A	INTRINSIC
low complexity region	795	809	N/A	INTRINSIC
RUN	1109	1177	3.66e-21	SMART
low complexity region	1235	1260	N/A	INTRINSIC
low complexity region	1289	1324	N/A	INTRINSIC
low complexity region	1330	1341	N/A	INTRINSIC
SH3	1457	1512	7.4e-11	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000107928

SMART Domains

Protein: ENSMUSP00000103561
Gene: ENSMUSG00000042788

Domain	Start	End	E-Value	Type
Pfam:DUF2475	15	76	1.3e-20	PFAM
Pfam:DUF2475	212	251	6.9e-10	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000107929

SMART Domains

Protein: ENSMUSP00000103562
Gene: ENSMUSG00000042788

Domain	Start	End	E-Value	Type
Pfam:DUF2475	15	76	1.5e-20	PFAM
Pfam:DUF2475	232	271	7.7e-10	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000123447

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000125393

Predicted Effect

probably damaging
Transcript: ENSMUST00000131668
AA Change: V1036A

PolyPhen 2 Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)

SMART Domains

Protein: ENSMUSP00000118528
Gene: ENSMUSG00000035969
AA Change: V1036A

Domain	Start	End	E-Value	Type
low complexity region	39	47	N/A	INTRINSIC
low complexity region	212	230	N/A	INTRINSIC
low complexity region	253	265	N/A	INTRINSIC
low complexity region	411	427	N/A	INTRINSIC
low complexity region	435	448	N/A	INTRINSIC
low complexity region	530	544	N/A	INTRINSIC
low complexity region	600	617	N/A	INTRINSIC
low complexity region	795	809	N/A	INTRINSIC
RUN	1109	1177	3.66e-21	SMART
low complexity region	1235	1260	N/A	INTRINSIC
low complexity region	1289	1324	N/A	INTRINSIC
low complexity region	1330	1341	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000150066

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000146710

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000154754

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000149556

Predicted Effect

probably benign
Transcript: ENSMUST00000149676

Predicted Effect

probably benign
Transcript: ENSMUST00000173682

SMART Domains

Protein: ENSMUSP00000133715
Gene: ENSMUSG00000035969

Domain	Start	End	E-Value	Type
low complexity region	39	47	N/A	INTRINSIC
low complexity region	212	230	N/A	INTRINSIC
low complexity region	253	265	N/A	INTRINSIC
low complexity region	411	427	N/A	INTRINSIC
low complexity region	435	448	N/A	INTRINSIC
low complexity region	530	544	N/A	INTRINSIC
low complexity region	685	703	N/A	INTRINSIC
low complexity region	733	740	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000155080

Predicted Effect

probably benign
Transcript: ENSMUST00000171134

SMART Domains

Protein: ENSMUSP00000127145
Gene: ENSMUSG00000042788

Domain	Start	End	E-Value	Type
Pfam:DUF2475	15	76	7.2e-21	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000149221

Meta Mutation Damage Score

0.1143

Coding Region Coverage

1x: 99.3%
3x: 98.7%
10x: 97.3%
20x: 95.6%

Validation Efficiency

93% (102/110)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a RUN and SH3 domain containing protein that interacts with Rab1b and Rab1-binding protein GM130. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2012]

Allele List at MGI

Other mutations in this stock

Total: 108 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700113H08Rik	T	C	10: 87,061,907 (GRCm39)	F119S	probably damaging	Het
Abca13	C	A	11: 9,531,545 (GRCm39)	Q4591K	probably damaging	Het
Anapc1	A	T	2: 128,476,631 (GRCm39)	M1329K	probably damaging	Het
Aoah	A	T	13: 21,163,710 (GRCm39)	K338*	probably null	Het
Ascc3	A	T	10: 50,521,154 (GRCm39)	T416S	probably benign	Het
Baz2a	A	G	10: 127,950,508 (GRCm39)	T484A	possibly damaging	Het
Btnl6	T	C	17: 34,727,477 (GRCm39)	N351S	probably benign	Het
Cacna1s	T	G	1: 136,046,544 (GRCm39)	I1772S	possibly damaging	Het
Ccdc8	A	G	7: 16,729,582 (GRCm39)	D357G	unknown	Het
Ccna1	T	C	3: 54,958,049 (GRCm39)	E152G	probably damaging	Het
Cct4	A	G	11: 22,949,073 (GRCm39)	D273G	probably damaging	Het
Cd9	A	G	6: 125,440,703 (GRCm39)	V96A	probably damaging	Het
Cdc5l	G	A	17: 45,726,610 (GRCm39)	R321W	probably damaging	Het
Cdh20	T	C	1: 109,922,036 (GRCm39)	S43P	probably benign	Het
Cep95	G	A	11: 106,702,097 (GRCm39)	V365M	probably benign	Het
Ces1c	T	C	8: 93,854,152 (GRCm39)	T128A	probably benign	Het
Chil5	A	G	3: 105,926,583 (GRCm39)	V82A	probably damaging	Het
Clmn	T	C	12: 104,748,023 (GRCm39)	D508G	probably benign	Het
Cog8	A	T	8: 107,775,777 (GRCm39)		probably benign	Het
Cst3	A	T	2: 148,717,089 (GRCm39)	V70E	probably damaging	Het
Ctcf	A	G	8: 106,390,671 (GRCm39)	T93A	possibly damaging	Het
Ctsk	C	A	3: 95,416,188 (GRCm39)	N315K	probably benign	Het
Cyp2j12	G	T	4: 96,029,262 (GRCm39)	D6E	probably benign	Het
Dhx34	A	G	7: 15,939,917 (GRCm39)	V655A	probably benign	Het
Dock10	T	C	1: 80,583,593 (GRCm39)	Y203C	probably damaging	Het
Dok7	A	T	5: 35,221,678 (GRCm39)	D26V	probably damaging	Het
Epha8	G	A	4: 136,667,597 (GRCm39)	H295Y	probably damaging	Het
Esf1	A	G	2: 139,990,843 (GRCm39)		probably benign	Het
Fam83c	A	G	2: 155,671,672 (GRCm39)	S588P	probably benign	Het
Fat3	G	A	9: 15,881,002 (GRCm39)		probably benign	Het
Fhdc1	T	C	3: 84,360,817 (GRCm39)		probably benign	Het
Frmd4b	A	G	6: 97,285,047 (GRCm39)	V338A	probably damaging	Het
Fsd1l	A	G	4: 53,694,727 (GRCm39)	T394A	probably damaging	Het
Gbf1	A	G	19: 46,242,549 (GRCm39)		probably benign	Het
Glg1	G	T	8: 111,886,490 (GRCm39)	Q1101K	possibly damaging	Het
Glt8d2	T	A	10: 82,487,361 (GRCm39)		probably null	Het
Gm19345	T	C	7: 19,588,855 (GRCm39)		probably benign	Het
Gpr179	A	T	11: 97,226,892 (GRCm39)	D1754E	probably benign	Het
Hydin	A	G	8: 111,291,650 (GRCm39)	T3381A	probably benign	Het
Igkv12-41	G	A	6: 69,835,822 (GRCm39)	T16I	possibly damaging	Het
Insl5	A	G	4: 102,875,313 (GRCm39)	*146Q	probably null	Het
Iqce	A	T	5: 140,651,957 (GRCm39)	I655N	possibly damaging	Het
Irf2bp1	G	A	7: 18,738,927 (GRCm39)	R189H	possibly damaging	Het
Itprid2	T	A	2: 79,490,810 (GRCm39)	L976Q	probably damaging	Het
Itsn1	C	T	16: 91,602,978 (GRCm39)		probably benign	Het
Kansl3	A	T	1: 36,384,050 (GRCm39)	I724N	probably benign	Het
Kcna4	T	C	2: 107,126,907 (GRCm39)	I547T	probably damaging	Het
Klk1b4	A	T	7: 43,860,158 (GRCm39)	I91F	probably benign	Het
Lmbr1	A	G	5: 29,457,753 (GRCm39)	S282P	probably damaging	Het
Lrrc17	G	A	5: 21,765,967 (GRCm39)	A150T	probably benign	Het
Lrrc2	A	G	9: 110,809,966 (GRCm39)	E334G	possibly damaging	Het
Lrrc7	G	A	3: 157,866,475 (GRCm39)	Q1077*	probably null	Het
Mapk8	A	T	14: 33,109,264 (GRCm39)		probably benign	Het
Mast1	T	A	8: 85,638,650 (GRCm39)	T1560S	probably benign	Het
Mdh1b	C	A	1: 63,758,777 (GRCm39)	A272S	probably damaging	Het
Myo15b	T	C	11: 115,777,109 (GRCm39)	Y912H	probably damaging	Het
Nf1	T	G	11: 79,299,525 (GRCm39)		probably null	Het
Nme7	T	A	1: 164,172,944 (GRCm39)	D218E	probably damaging	Het
Nsun7	T	A	5: 66,446,751 (GRCm39)		probably benign	Het
Nxpe2	A	G	9: 48,251,870 (GRCm39)		probably null	Het
Or1e34	A	G	11: 73,778,655 (GRCm39)	V181A	probably benign	Het
Or2ag16	G	A	7: 106,352,196 (GRCm39)	T133I	probably benign	Het
Or2n1c	T	G	17: 38,519,286 (GRCm39)	I50R	probably benign	Het
Or5p53	T	A	7: 107,533,375 (GRCm39)	V216D	probably damaging	Het
P2ry1	T	C	3: 60,910,951 (GRCm39)	V30A	probably benign	Het
Pgm2	T	A	5: 64,269,386 (GRCm39)	I491N	possibly damaging	Het
Pkd1l3	A	T	8: 110,365,386 (GRCm39)	D1169V	probably damaging	Het
Poldip2	T	A	11: 78,403,189 (GRCm39)	S18T	probably benign	Het
Prg4	C	T	1: 150,331,558 (GRCm39)		probably benign	Het
Prkab2	T	A	3: 97,574,728 (GRCm39)	Y241*	probably null	Het
Prmt7	A	G	8: 106,953,839 (GRCm39)		probably benign	Het
Proser3	T	A	7: 30,245,842 (GRCm39)	R80W	probably damaging	Het
Prr12	A	G	7: 44,699,415 (GRCm39)		probably benign	Het
Psmd1	A	T	1: 86,006,304 (GRCm39)	L223F	probably damaging	Het
Rab13	A	G	3: 90,131,088 (GRCm39)		probably benign	Het
Rgl1	C	T	1: 152,428,347 (GRCm39)	C294Y	probably damaging	Het
Rpl21-ps4	C	A	14: 11,227,556 (GRCm38)		noncoding transcript	Het
Sae1	T	A	7: 16,104,247 (GRCm39)	K121*	probably null	Het
Sap130	C	T	18: 31,813,559 (GRCm39)	P539S	probably damaging	Het
Saxo4	C	T	19: 10,452,418 (GRCm39)	R364Q	probably damaging	Het
Scube2	A	G	7: 109,424,079 (GRCm39)	L475P	probably damaging	Het
Sec16a	T	C	2: 26,321,198 (GRCm39)	D1298G	probably damaging	Het
Serpinb9b	T	C	13: 33,222,003 (GRCm39)	F206L	probably benign	Het
Sh3bp1	T	A	15: 78,788,534 (GRCm39)	Y202*	probably null	Het
Shprh	T	A	10: 11,062,135 (GRCm39)	C1177S	possibly damaging	Het
Slc27a6	T	C	18: 58,742,937 (GRCm39)	Y542H	possibly damaging	Het
Slc41a1	T	C	1: 131,771,650 (GRCm39)		probably benign	Het
Slc46a1	T	C	11: 78,361,625 (GRCm39)	F424L	probably damaging	Het
Slc66a2	C	T	18: 80,306,733 (GRCm39)	A101V	probably benign	Het
Slc6a12	G	A	6: 121,333,877 (GRCm39)	V238I	probably damaging	Het
Slc6a20a	A	G	9: 123,493,686 (GRCm39)	V65A	probably damaging	Het
Slc9c1	T	A	16: 45,374,663 (GRCm39)	S343T	probably benign	Het
Spcs3	C	A	8: 54,981,415 (GRCm39)	R60I	probably benign	Het
Tbc1d16	C	A	11: 119,038,401 (GRCm39)	R764L	possibly damaging	Het
Tcaf2	A	T	6: 42,619,838 (GRCm39)	V63E	possibly damaging	Het
Tmc1	G	T	19: 20,766,951 (GRCm39)	A750E	possibly damaging	Het
Tmem273	A	G	14: 32,530,320 (GRCm39)	K83E	possibly damaging	Het
Tmem81	C	G	1: 132,435,567 (GRCm39)	I124M	probably damaging	Het
Tmx3	T	C	18: 90,558,130 (GRCm39)	I394T	probably damaging	Het
Trank1	G	A	9: 111,195,092 (GRCm39)	E1039K	possibly damaging	Het
Trpc4ap	A	G	2: 155,499,866 (GRCm39)		probably benign	Het
Tsen54	T	C	11: 115,706,234 (GRCm39)	C123R	probably damaging	Het
Ubtd1	A	G	19: 42,020,373 (GRCm39)	D39G	possibly damaging	Het
Vmn1r181	A	T	7: 23,683,759 (GRCm39)	M75L	probably benign	Het
Zc3h7a	T	C	16: 10,958,601 (GRCm39)	T847A	probably damaging	Het
Zc3hav1	A	G	6: 38,313,485 (GRCm39)	C187R	probably damaging	Het
Zfp692	G	A	11: 58,201,229 (GRCm39)		probably benign	Het
Zmiz1	G	A	14: 25,654,919 (GRCm39)		probably benign	Het

Other mutations in Rusc2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01358:Rusc2	APN	4	43,426,116 (GRCm39)	missense	probably damaging	0.97
IGL01474:Rusc2	APN	4	43,416,434 (GRCm39)	missense	probably damaging	0.98
IGL01541:Rusc2	APN	4	43,415,840 (GRCm39)	missense	probably benign	0.08
IGL01628:Rusc2	APN	4	43,425,729 (GRCm39)	missense	probably damaging	1.00
IGL01969:Rusc2	APN	4	43,415,738 (GRCm39)	missense	probably benign	0.02
IGL02030:Rusc2	APN	4	43,416,095 (GRCm39)	missense	possibly damaging	0.86
IGL02079:Rusc2	APN	4	43,425,668 (GRCm39)	missense	probably benign
IGL02115:Rusc2	APN	4	43,426,136 (GRCm39)	splice site	probably benign
IGL02122:Rusc2	APN	4	43,421,685 (GRCm39)	missense	possibly damaging	0.67
IGL02350:Rusc2	APN	4	43,425,351 (GRCm39)	missense	possibly damaging	0.86
IGL02357:Rusc2	APN	4	43,425,351 (GRCm39)	missense	possibly damaging	0.86
IGL02437:Rusc2	APN	4	43,415,545 (GRCm39)	missense	probably damaging	1.00
IGL02930:Rusc2	APN	4	43,416,376 (GRCm39)	missense	probably damaging	0.99
IGL03154:Rusc2	APN	4	43,425,806 (GRCm39)	missense	probably benign	0.00
P0026:Rusc2	UTSW	4	43,415,840 (GRCm39)	missense	possibly damaging	0.93
R0036:Rusc2	UTSW	4	43,424,009 (GRCm39)	missense	probably damaging	1.00
R0068:Rusc2	UTSW	4	43,424,100 (GRCm39)	splice site	probably benign
R0068:Rusc2	UTSW	4	43,424,100 (GRCm39)	splice site	probably benign
R0114:Rusc2	UTSW	4	43,422,055 (GRCm39)	missense	probably damaging	1.00
R0471:Rusc2	UTSW	4	43,425,486 (GRCm39)	missense	probably damaging	0.99
R1381:Rusc2	UTSW	4	43,416,137 (GRCm39)	missense	probably damaging	1.00
R1413:Rusc2	UTSW	4	43,416,568 (GRCm39)	missense	probably benign	0.00
R1416:Rusc2	UTSW	4	43,421,617 (GRCm39)	missense	possibly damaging	0.86
R1731:Rusc2	UTSW	4	43,426,046 (GRCm39)	missense	probably benign
R1864:Rusc2	UTSW	4	43,421,719 (GRCm39)	missense	possibly damaging	0.49
R1897:Rusc2	UTSW	4	43,421,749 (GRCm39)	missense	probably damaging	1.00
R2010:Rusc2	UTSW	4	43,415,212 (GRCm39)	missense	probably benign	0.06
R2212:Rusc2	UTSW	4	43,415,935 (GRCm39)	missense	probably damaging	1.00
R2275:Rusc2	UTSW	4	43,416,260 (GRCm39)	missense	probably damaging	1.00
R2885:Rusc2	UTSW	4	43,415,456 (GRCm39)	missense	probably benign	0.28
R2886:Rusc2	UTSW	4	43,415,456 (GRCm39)	missense	probably benign	0.28
R3412:Rusc2	UTSW	4	43,415,935 (GRCm39)	missense	probably damaging	1.00
R3413:Rusc2	UTSW	4	43,415,935 (GRCm39)	missense	probably damaging	1.00
R3414:Rusc2	UTSW	4	43,415,935 (GRCm39)	missense	probably damaging	1.00
R3852:Rusc2	UTSW	4	43,416,424 (GRCm39)	missense	probably benign	0.45
R4135:Rusc2	UTSW	4	43,425,563 (GRCm39)	missense	possibly damaging	0.49
R4272:Rusc2	UTSW	4	43,415,533 (GRCm39)	missense	probably damaging	1.00
R4574:Rusc2	UTSW	4	43,416,080 (GRCm39)	missense	probably damaging	0.99
R4888:Rusc2	UTSW	4	43,423,942 (GRCm39)	missense	probably damaging	1.00
R5010:Rusc2	UTSW	4	43,415,926 (GRCm39)	missense	probably damaging	1.00
R5071:Rusc2	UTSW	4	43,415,240 (GRCm39)	missense	probably benign	0.05
R5131:Rusc2	UTSW	4	43,414,948 (GRCm39)	missense	probably benign	0.03
R5177:Rusc2	UTSW	4	43,421,805 (GRCm39)	splice site	probably null
R5540:Rusc2	UTSW	4	43,423,975 (GRCm39)	missense	probably damaging	1.00
R5561:Rusc2	UTSW	4	43,415,932 (GRCm39)	nonsense	probably null
R5628:Rusc2	UTSW	4	43,425,348 (GRCm39)	missense	probably damaging	1.00
R5645:Rusc2	UTSW	4	43,425,758 (GRCm39)	missense	probably benign	0.06
R6129:Rusc2	UTSW	4	43,424,271 (GRCm39)	missense	probably damaging	1.00
R6362:Rusc2	UTSW	4	43,416,416 (GRCm39)	missense	probably benign	0.30
R6633:Rusc2	UTSW	4	43,414,852 (GRCm39)	missense	probably damaging	0.99
R6980:Rusc2	UTSW	4	43,422,846 (GRCm39)	missense	probably benign	0.35
R7491:Rusc2	UTSW	4	43,426,528 (GRCm39)	missense	probably damaging	1.00
R7641:Rusc2	UTSW	4	43,425,335 (GRCm39)	missense	possibly damaging	0.84
R7698:Rusc2	UTSW	4	43,414,900 (GRCm39)	nonsense	probably null
R7710:Rusc2	UTSW	4	43,416,119 (GRCm39)	missense	probably benign	0.07
R8052:Rusc2	UTSW	4	43,421,851 (GRCm39)	missense	probably benign
R8061:Rusc2	UTSW	4	43,422,492 (GRCm39)	missense	probably damaging	1.00
R8127:Rusc2	UTSW	4	43,423,747 (GRCm39)	missense	possibly damaging	0.54
R8319:Rusc2	UTSW	4	43,425,378 (GRCm39)	missense	probably damaging	1.00
R8355:Rusc2	UTSW	4	43,422,846 (GRCm39)	missense	probably benign	0.35
R8397:Rusc2	UTSW	4	43,424,206 (GRCm39)	missense	possibly damaging	0.95
R8455:Rusc2	UTSW	4	43,422,846 (GRCm39)	missense	probably benign	0.35
R8553:Rusc2	UTSW	4	43,416,508 (GRCm39)	missense	probably benign	0.05
R8725:Rusc2	UTSW	4	43,401,351 (GRCm39)	intron	probably benign
R8725:Rusc2	UTSW	4	43,415,396 (GRCm39)	missense	probably damaging	0.99
R8727:Rusc2	UTSW	4	43,401,351 (GRCm39)	intron	probably benign
R8834:Rusc2	UTSW	4	43,416,431 (GRCm39)	missense	possibly damaging	0.94
R9295:Rusc2	UTSW	4	43,416,382 (GRCm39)	missense	probably damaging	0.98
R9483:Rusc2	UTSW	4	43,415,897 (GRCm39)	missense	probably damaging	0.97
R9666:Rusc2	UTSW	4	43,416,262 (GRCm39)	missense	probably benign	0.21
R9705:Rusc2	UTSW	4	43,424,936 (GRCm39)	missense	probably benign	0.00
X0025:Rusc2	UTSW	4	43,422,226 (GRCm39)	missense	probably benign	0.00
X0066:Rusc2	UTSW	4	43,422,204 (GRCm39)	nonsense	probably null

Predicted Primers

PCR Primer
(F):5'- CACTATCAAGAGCTGAGCTATGCCC -3'
(R):5'- TGTTGTAGAGGCCATGCAAGACC -3'

Sequencing Primer
(F):5'- GGTCTGACTAAGCCAGACTAAG -3'
(R):5'- CATGCAAGACCTTGGTGGATG -3'

Posted On

2013-05-09