Incidental Mutation 'R5771:Nlrp4a'
| ID |
445360 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nlrp4a
|
| Ensembl Gene |
ENSMUSG00000040601 |
| Gene Name |
NLR family, pyrin domain containing 4A |
| Synonyms |
Nalp-eta, E330028A19Rik, Nalp4a |
| MMRRC Submission |
043371-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.079)
|
| Stock # |
R5771 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
26134538-26175100 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 26152814 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Tyrosine
at position 628
(C628Y)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000146044
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068767]
[ENSMUST00000119386]
[ENSMUST00000146907]
|
| AlphaFold |
Q8BU40 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000068767
AA Change: C628Y
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000066841
Gene: ENSMUSG00000040601
AA Change: C628Y
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
6 |
89 |
6.48e-34 |
SMART |
|
Pfam:NACHT
|
148 |
317 |
4.9e-37 |
PFAM |
|
Blast:LRR
|
634 |
661 |
4e-6 |
BLAST |
|
low complexity region
|
666 |
677 |
N/A |
INTRINSIC |
|
LRR
|
689 |
716 |
5.96e0 |
SMART |
|
LRR
|
718 |
745 |
1.99e1 |
SMART |
|
LRR
|
746 |
772 |
1.02e0 |
SMART |
|
LRR
|
774 |
801 |
4.66e1 |
SMART |
|
LRR
|
802 |
829 |
1.18e-2 |
SMART |
|
LRR
|
831 |
858 |
2.2e-2 |
SMART |
|
LRR
|
859 |
886 |
5.59e-4 |
SMART |
|
LRR
|
888 |
915 |
9.41e0 |
SMART |
|
LRR
|
916 |
943 |
8.94e1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000119386
AA Change: C628Y
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000112441
Gene: ENSMUSG00000040601
AA Change: C628Y
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
6 |
89 |
6.48e-34 |
SMART |
|
Pfam:NACHT
|
148 |
317 |
1.3e-37 |
PFAM |
|
Blast:LRR
|
634 |
661 |
4e-6 |
BLAST |
|
low complexity region
|
666 |
677 |
N/A |
INTRINSIC |
|
LRR
|
689 |
716 |
5.96e0 |
SMART |
|
LRR
|
718 |
745 |
1.99e1 |
SMART |
|
LRR
|
746 |
772 |
1.02e0 |
SMART |
|
LRR
|
774 |
801 |
4.66e1 |
SMART |
|
LRR
|
802 |
829 |
1.18e-2 |
SMART |
|
LRR
|
831 |
858 |
2.2e-2 |
SMART |
|
LRR
|
859 |
886 |
5.59e-4 |
SMART |
|
LRR
|
888 |
915 |
9.41e0 |
SMART |
|
LRR
|
916 |
943 |
8.94e1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146534
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000146907
AA Change: C628Y
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| Meta Mutation Damage Score |
0.3621 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.4%
- 20x: 95.8%
|
| Validation Efficiency |
95% (87/92) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 82 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
T |
A |
11: 9,241,411 (GRCm39) |
N1091K |
probably damaging |
Het |
| Adam3 |
C |
T |
8: 25,197,427 (GRCm39) |
V335I |
probably benign |
Het |
| AI504432 |
G |
A |
3: 106,956,299 (GRCm39) |
|
noncoding transcript |
Het |
| Apcdd1 |
A |
G |
18: 63,070,027 (GRCm39) |
Y98C |
probably damaging |
Het |
| Aqp9 |
C |
T |
9: 71,030,146 (GRCm39) |
A214T |
probably damaging |
Het |
| Atp8b4 |
T |
C |
2: 126,220,664 (GRCm39) |
D578G |
probably benign |
Het |
| Bcdin3d |
T |
C |
15: 99,368,717 (GRCm39) |
M161V |
probably benign |
Het |
| Bicral |
C |
T |
17: 47,136,284 (GRCm39) |
V309I |
possibly damaging |
Het |
| Ccdc88b |
C |
T |
19: 6,831,203 (GRCm39) |
A580T |
probably benign |
Het |
| Cdhr2 |
T |
A |
13: 54,874,508 (GRCm39) |
V860E |
probably damaging |
Het |
| Clhc1 |
A |
T |
11: 29,513,854 (GRCm39) |
N302Y |
possibly damaging |
Het |
| Cnnm2 |
T |
A |
19: 46,845,434 (GRCm39) |
|
probably null |
Het |
| Crebbp |
T |
C |
16: 3,937,636 (GRCm39) |
N709S |
probably benign |
Het |
| Ctnnal1 |
T |
C |
4: 56,826,328 (GRCm39) |
S512G |
probably benign |
Het |
| Dgcr8 |
C |
T |
16: 18,090,632 (GRCm39) |
V581I |
probably benign |
Het |
| Dnaaf10 |
A |
G |
11: 17,174,638 (GRCm39) |
T169A |
probably benign |
Het |
| Dnah7c |
G |
A |
1: 46,678,825 (GRCm39) |
V1790I |
probably benign |
Het |
| Efl1 |
A |
G |
7: 82,341,732 (GRCm39) |
K452E |
probably benign |
Het |
| Epb42 |
A |
C |
2: 120,852,301 (GRCm39) |
V564G |
probably damaging |
Het |
| Etv4 |
G |
A |
11: 101,662,282 (GRCm39) |
P335S |
probably damaging |
Het |
| Fbxw9 |
T |
A |
8: 85,791,201 (GRCm39) |
|
probably null |
Het |
| Fcrl2 |
A |
T |
3: 87,170,775 (GRCm39) |
L3Q |
probably damaging |
Het |
| Frmd8 |
C |
A |
19: 5,919,478 (GRCm39) |
A190S |
probably benign |
Het |
| Gcm2 |
C |
T |
13: 41,256,991 (GRCm39) |
D253N |
probably benign |
Het |
| Gfm1 |
T |
C |
3: 67,342,895 (GRCm39) |
V143A |
probably benign |
Het |
| Gigyf2 |
T |
C |
1: 87,374,050 (GRCm39) |
M1226T |
possibly damaging |
Het |
| Gm10110 |
C |
T |
14: 90,134,675 (GRCm39) |
|
noncoding transcript |
Het |
| Gm11595 |
G |
A |
11: 99,663,381 (GRCm39) |
R100C |
unknown |
Het |
| Gm20939 |
T |
G |
17: 95,181,767 (GRCm39) |
C55W |
possibly damaging |
Het |
| Gm5407 |
T |
A |
16: 49,117,229 (GRCm39) |
|
noncoding transcript |
Het |
| Golga4 |
A |
G |
9: 118,387,351 (GRCm39) |
E1491G |
probably damaging |
Het |
| Hdac11 |
T |
A |
6: 91,146,364 (GRCm39) |
|
probably null |
Het |
| Hs3st3b1 |
C |
T |
11: 63,780,098 (GRCm39) |
S343N |
probably benign |
Het |
| Igkv12-44 |
G |
A |
6: 69,792,075 (GRCm39) |
P4S |
probably benign |
Het |
| Igkv1-35 |
C |
T |
6: 69,988,231 (GRCm39) |
V22I |
probably benign |
Het |
| Kcns2 |
A |
T |
15: 34,839,068 (GRCm39) |
T144S |
probably benign |
Het |
| Khdc1c |
T |
C |
1: 21,439,266 (GRCm39) |
V84A |
possibly damaging |
Het |
| Kif4-ps |
T |
A |
12: 101,115,544 (GRCm39) |
|
noncoding transcript |
Het |
| Lamc2 |
T |
G |
1: 153,017,340 (GRCm39) |
Y549S |
probably benign |
Het |
| Lect2 |
T |
A |
13: 56,696,154 (GRCm39) |
I8F |
probably benign |
Het |
| Loxl3 |
T |
A |
6: 83,012,780 (GRCm39) |
|
probably null |
Het |
| Lrwd1 |
A |
T |
5: 136,152,516 (GRCm39) |
I545N |
possibly damaging |
Het |
| Ltbp3 |
T |
C |
19: 5,797,572 (GRCm39) |
C437R |
probably damaging |
Het |
| Lypd3 |
T |
C |
7: 24,339,787 (GRCm39) |
S285P |
probably benign |
Het |
| Mast2 |
T |
A |
4: 116,190,622 (GRCm39) |
H83L |
possibly damaging |
Het |
| Mfsd4b4 |
A |
G |
10: 39,768,635 (GRCm39) |
F153L |
probably benign |
Het |
| Ms4a4b |
T |
A |
19: 11,438,606 (GRCm39) |
|
probably null |
Het |
| Nbr1 |
T |
A |
11: 101,450,364 (GRCm39) |
L41Q |
probably damaging |
Het |
| Nup160 |
C |
T |
2: 90,553,740 (GRCm39) |
R1157C |
probably damaging |
Het |
| Obscn |
T |
A |
11: 58,891,533 (GRCm39) |
I7000F |
unknown |
Het |
| Or4k41 |
T |
A |
2: 111,280,406 (GRCm39) |
|
probably null |
Het |
| Or4p21 |
A |
T |
2: 88,276,652 (GRCm39) |
V210D |
possibly damaging |
Het |
| Or5ac15 |
TGAAGAAGAA |
TGAAGAA |
16: 58,940,335 (GRCm39) |
|
probably benign |
Het |
| Or5b122 |
T |
G |
19: 13,562,872 (GRCm39) |
V25G |
probably damaging |
Het |
| Or8g2 |
A |
T |
9: 39,821,546 (GRCm39) |
Y149F |
probably damaging |
Het |
| Pdilt |
T |
C |
7: 119,094,217 (GRCm39) |
K345E |
probably damaging |
Het |
| Ppp1r12b |
A |
T |
1: 134,701,162 (GRCm39) |
|
probably null |
Het |
| Ppp2r1b |
A |
T |
9: 50,778,132 (GRCm39) |
Q219L |
probably damaging |
Het |
| Prim2 |
A |
G |
1: 33,493,232 (GRCm39) |
S485P |
unknown |
Het |
| Prkdc |
A |
G |
16: 15,482,097 (GRCm39) |
D380G |
probably damaging |
Het |
| Psmg1 |
A |
G |
16: 95,783,369 (GRCm39) |
L243S |
probably damaging |
Het |
| Rapgef5 |
T |
A |
12: 117,685,061 (GRCm39) |
V270D |
probably benign |
Het |
| Rnft1 |
C |
T |
11: 86,384,032 (GRCm39) |
R311* |
probably null |
Het |
| Scaper |
T |
A |
9: 55,724,075 (GRCm39) |
I628L |
probably damaging |
Het |
| Serpina3j |
C |
A |
12: 104,281,185 (GRCm39) |
H119Q |
possibly damaging |
Het |
| Slamf6 |
G |
A |
1: 171,745,341 (GRCm39) |
V23I |
probably damaging |
Het |
| Slc12a5 |
T |
A |
2: 164,815,688 (GRCm39) |
M45K |
possibly damaging |
Het |
| Slc25a11 |
A |
C |
11: 70,537,016 (GRCm39) |
V13G |
probably damaging |
Het |
| Slc7a14 |
T |
A |
3: 31,292,856 (GRCm39) |
Y143F |
probably damaging |
Het |
| Spryd3 |
A |
G |
15: 102,025,342 (GRCm39) |
|
probably benign |
Het |
| Stard13 |
C |
A |
5: 151,113,476 (GRCm39) |
L28F |
probably damaging |
Het |
| Susd2 |
C |
T |
10: 75,473,853 (GRCm39) |
A581T |
probably damaging |
Het |
| Taf2 |
A |
G |
15: 54,923,335 (GRCm39) |
V314A |
probably benign |
Het |
| Tas2r106 |
T |
C |
6: 131,655,086 (GRCm39) |
N255S |
possibly damaging |
Het |
| Tbxa2r |
T |
A |
10: 81,168,775 (GRCm39) |
W155R |
probably damaging |
Het |
| Tcf3 |
A |
G |
10: 80,257,450 (GRCm39) |
|
probably benign |
Het |
| Ticam1 |
TCACACA |
TCACA |
17: 56,577,629 (GRCm39) |
|
probably null |
Het |
| Vmn2r55 |
T |
C |
7: 12,404,959 (GRCm39) |
D148G |
probably damaging |
Het |
| Vmn2r77 |
A |
G |
7: 86,461,235 (GRCm39) |
N854D |
probably benign |
Het |
| Vstm4 |
A |
T |
14: 32,626,526 (GRCm39) |
H64L |
probably benign |
Het |
| Wnk2 |
T |
C |
13: 49,256,276 (GRCm39) |
T282A |
probably damaging |
Het |
| Zscan4c |
A |
T |
7: 10,743,574 (GRCm39) |
D391V |
probably benign |
Het |
|
| Other mutations in Nlrp4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00487:Nlrp4a
|
APN |
7 |
26,149,410 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL00972:Nlrp4a
|
APN |
7 |
26,156,473 (GRCm39) |
missense |
probably benign |
|
|
IGL01081:Nlrp4a
|
APN |
7 |
26,149,254 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01788:Nlrp4a
|
APN |
7 |
26,153,492 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02001:Nlrp4a
|
APN |
7 |
26,149,394 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02070:Nlrp4a
|
APN |
7 |
26,148,703 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02175:Nlrp4a
|
APN |
7 |
26,174,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02193:Nlrp4a
|
APN |
7 |
26,148,703 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02193:Nlrp4a
|
APN |
7 |
26,159,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02197:Nlrp4a
|
APN |
7 |
26,148,703 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02200:Nlrp4a
|
APN |
7 |
26,148,703 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02202:Nlrp4a
|
APN |
7 |
26,148,703 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02207:Nlrp4a
|
APN |
7 |
26,148,703 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02237:Nlrp4a
|
APN |
7 |
26,148,703 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02240:Nlrp4a
|
APN |
7 |
26,148,703 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
IGL02658:Nlrp4a
|
APN |
7 |
26,149,138 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL02743:Nlrp4a
|
APN |
7 |
26,159,240 (GRCm39) |
splice site |
probably benign |
|
|
IGL02960:Nlrp4a
|
APN |
7 |
26,149,155 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03064:Nlrp4a
|
APN |
7 |
26,148,934 (GRCm39) |
missense |
probably benign |
0.23 |
|
IGL03276:Nlrp4a
|
APN |
7 |
26,163,615 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB002:Nlrp4a
|
UTSW |
7 |
26,150,011 (GRCm39) |
missense |
probably benign |
0.10 |
|
BB012:Nlrp4a
|
UTSW |
7 |
26,150,011 (GRCm39) |
missense |
probably benign |
0.10 |
|
D3080:Nlrp4a
|
UTSW |
7 |
26,143,766 (GRCm39) |
missense |
probably benign |
0.22 |
|
P0019:Nlrp4a
|
UTSW |
7 |
26,149,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0020:Nlrp4a
|
UTSW |
7 |
26,149,797 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0240:Nlrp4a
|
UTSW |
7 |
26,161,941 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0240:Nlrp4a
|
UTSW |
7 |
26,161,941 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0372:Nlrp4a
|
UTSW |
7 |
26,148,657 (GRCm39) |
splice site |
probably benign |
|
|
R0466:Nlrp4a
|
UTSW |
7 |
26,162,045 (GRCm39) |
splice site |
probably benign |
|
|
R0544:Nlrp4a
|
UTSW |
7 |
26,156,555 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1006:Nlrp4a
|
UTSW |
7 |
26,152,892 (GRCm39) |
missense |
probably benign |
0.30 |
|
R1072:Nlrp4a
|
UTSW |
7 |
26,143,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1432:Nlrp4a
|
UTSW |
7 |
26,163,622 (GRCm39) |
frame shift |
probably null |
|
|
R1655:Nlrp4a
|
UTSW |
7 |
26,149,076 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1696:Nlrp4a
|
UTSW |
7 |
26,149,959 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2041:Nlrp4a
|
UTSW |
7 |
26,149,611 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2091:Nlrp4a
|
UTSW |
7 |
26,149,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2163:Nlrp4a
|
UTSW |
7 |
26,152,822 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2174:Nlrp4a
|
UTSW |
7 |
26,148,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2319:Nlrp4a
|
UTSW |
7 |
26,149,319 (GRCm39) |
missense |
probably benign |
0.10 |
|
R2358:Nlrp4a
|
UTSW |
7 |
26,163,623 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2680:Nlrp4a
|
UTSW |
7 |
26,148,655 (GRCm39) |
splice site |
probably null |
|
|
R3812:Nlrp4a
|
UTSW |
7 |
26,149,118 (GRCm39) |
missense |
probably benign |
|
|
R4114:Nlrp4a
|
UTSW |
7 |
26,149,365 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4664:Nlrp4a
|
UTSW |
7 |
26,148,943 (GRCm39) |
nonsense |
probably null |
|
|
R4676:Nlrp4a
|
UTSW |
7 |
26,149,654 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4708:Nlrp4a
|
UTSW |
7 |
26,163,533 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4728:Nlrp4a
|
UTSW |
7 |
26,174,515 (GRCm39) |
missense |
probably benign |
0.24 |
|
R4815:Nlrp4a
|
UTSW |
7 |
26,150,233 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4831:Nlrp4a
|
UTSW |
7 |
26,149,844 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5007:Nlrp4a
|
UTSW |
7 |
26,161,905 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5253:Nlrp4a
|
UTSW |
7 |
26,149,917 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5262:Nlrp4a
|
UTSW |
7 |
26,159,236 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5441:Nlrp4a
|
UTSW |
7 |
26,153,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5639:Nlrp4a
|
UTSW |
7 |
26,156,455 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5641:Nlrp4a
|
UTSW |
7 |
26,149,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6312:Nlrp4a
|
UTSW |
7 |
26,148,821 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7131:Nlrp4a
|
UTSW |
7 |
26,149,258 (GRCm39) |
missense |
probably benign |
0.21 |
|
R7149:Nlrp4a
|
UTSW |
7 |
26,149,863 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7348:Nlrp4a
|
UTSW |
7 |
26,143,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7384:Nlrp4a
|
UTSW |
7 |
26,148,963 (GRCm39) |
missense |
not run |
|
|
R7548:Nlrp4a
|
UTSW |
7 |
26,149,604 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7566:Nlrp4a
|
UTSW |
7 |
26,148,670 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7646:Nlrp4a
|
UTSW |
7 |
26,148,987 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7692:Nlrp4a
|
UTSW |
7 |
26,148,690 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7902:Nlrp4a
|
UTSW |
7 |
26,149,482 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7925:Nlrp4a
|
UTSW |
7 |
26,150,011 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7937:Nlrp4a
|
UTSW |
7 |
26,163,571 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7992:Nlrp4a
|
UTSW |
7 |
26,150,070 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8205:Nlrp4a
|
UTSW |
7 |
26,150,219 (GRCm39) |
missense |
probably benign |
|
|
R8477:Nlrp4a
|
UTSW |
7 |
26,159,219 (GRCm39) |
missense |
probably benign |
|
|
R8704:Nlrp4a
|
UTSW |
7 |
26,156,563 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8791:Nlrp4a
|
UTSW |
7 |
26,143,561 (GRCm39) |
splice site |
probably benign |
|
|
R9220:Nlrp4a
|
UTSW |
7 |
26,149,523 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9332:Nlrp4a
|
UTSW |
7 |
26,159,077 (GRCm39) |
missense |
probably damaging |
0.99 |
|
T0975:Nlrp4a
|
UTSW |
7 |
26,149,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0022:Nlrp4a
|
UTSW |
7 |
26,143,767 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1088:Nlrp4a
|
UTSW |
7 |
26,153,588 (GRCm39) |
missense |
probably benign |
0.01 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTGTGAATGGCTTGACTTAAC -3'
(R):5'- GAAAGGCTAGTCTGTTACTTCTGG -3'
Sequencing Primer
(F):5'- TTATGGATAAGTGTGAGCCACC -3'
(R):5'- TCTGGTATGCCTACATCAAATAGAC -3'
|
| Posted On |
2016-11-21 |
Incidental Mutation