Incidental Mutation 'R2511:Pcdh15'
| ID |
476550 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcdh15
|
| Ensembl Gene |
ENSMUSG00000052613 |
| Gene Name |
protocadherin 15 |
| Synonyms |
Gm9815, nmf19, roda, Ush1f |
| MMRRC Submission |
040417-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R2511 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
72935174-74485569 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 74481828 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 391
(D391G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000134863
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000124046]
[ENSMUST00000125517]
[ENSMUST00000131724]
[ENSMUST00000144302]
[ENSMUST00000146682]
[ENSMUST00000149977]
[ENSMUST00000195531]
[ENSMUST00000193739]
[ENSMUST00000177107]
[ENSMUST00000191854]
[ENSMUST00000155701]
[ENSMUST00000191709]
[ENSMUST00000152655]
[ENSMUST00000152819]
[ENSMUST00000193174]
[ENSMUST00000151116]
|
| AlphaFold |
Q99PJ1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000124046
|
| SMART Domains |
Protein: ENSMUSP00000121130
Gene: ENSMUSG00000052613
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
30 |
118 |
7.87e-9 |
SMART |
|
CA
|
142 |
224 |
4.88e-14 |
SMART |
|
CA
|
249 |
326 |
4.65e-20 |
SMART |
|
CA
|
350 |
428 |
1.93e-26 |
SMART |
|
CA
|
452 |
535 |
5.69e-15 |
SMART |
|
CA
|
559 |
645 |
6.85e-9 |
SMART |
|
CA
|
666 |
753 |
3.09e-16 |
SMART |
|
CA
|
777 |
861 |
4.49e-4 |
SMART |
|
transmembrane domain
|
986 |
1008 |
N/A |
INTRINSIC |
|
low complexity region
|
1029 |
1056 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125517
|
| SMART Domains |
Protein: ENSMUSP00000115399
Gene: ENSMUSG00000052613
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
CA
|
64 |
145 |
1.22e-1 |
SMART |
|
CA
|
174 |
263 |
5.48e-8 |
SMART |
|
CA
|
304 |
393 |
1.94e-8 |
SMART |
|
low complexity region
|
430 |
468 |
N/A |
INTRINSIC |
|
low complexity region
|
521 |
584 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
641 |
N/A |
INTRINSIC |
|
low complexity region
|
657 |
685 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000127928
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131724
|
| SMART Domains |
Protein: ENSMUSP00000122466
Gene: ENSMUSG00000052613
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
CA
|
64 |
145 |
1.22e-1 |
SMART |
|
CA
|
174 |
263 |
5.48e-8 |
SMART |
|
CA
|
304 |
393 |
1.94e-8 |
SMART |
|
CA
|
426 |
507 |
2.29e-10 |
SMART |
|
CA
|
531 |
613 |
4.88e-14 |
SMART |
|
CA
|
638 |
715 |
4.65e-20 |
SMART |
|
CA
|
739 |
817 |
1.93e-26 |
SMART |
|
CA
|
841 |
924 |
5.69e-15 |
SMART |
|
CA
|
948 |
1034 |
6.85e-9 |
SMART |
|
CA
|
1055 |
1142 |
3.09e-16 |
SMART |
|
CA
|
1166 |
1250 |
4.49e-4 |
SMART |
|
transmembrane domain
|
1375 |
1397 |
N/A |
INTRINSIC |
|
low complexity region
|
1418 |
1445 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000144302
|
| SMART Domains |
Protein: ENSMUSP00000122606
Gene: ENSMUSG00000052613
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
CA
|
64 |
145 |
1.22e-1 |
SMART |
|
CA
|
174 |
263 |
5.48e-8 |
SMART |
|
low complexity region
|
313 |
326 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000146682
AA Change: D391G
PolyPhen 2
Score 0.940 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000134863
Gene: ENSMUSG00000052613
AA Change: D391G
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
128 |
150 |
N/A |
INTRINSIC |
|
low complexity region
|
215 |
232 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000149977
AA Change: D1651G
PolyPhen 2
Score 0.165 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000118833
Gene: ENSMUSG00000052613
AA Change: D1651G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
CA
|
64 |
145 |
1.22e-1 |
SMART |
|
CA
|
174 |
263 |
5.48e-8 |
SMART |
|
CA
|
304 |
393 |
1.94e-8 |
SMART |
|
CA
|
426 |
507 |
2.29e-10 |
SMART |
|
CA
|
531 |
613 |
4.88e-14 |
SMART |
|
CA
|
638 |
715 |
4.65e-20 |
SMART |
|
CA
|
739 |
817 |
1.93e-26 |
SMART |
|
CA
|
841 |
924 |
5.69e-15 |
SMART |
|
CA
|
948 |
1034 |
6.85e-9 |
SMART |
|
CA
|
1055 |
1142 |
3.09e-16 |
SMART |
|
CA
|
1166 |
1250 |
4.49e-4 |
SMART |
|
transmembrane domain
|
1375 |
1397 |
N/A |
INTRINSIC |
|
low complexity region
|
1418 |
1445 |
N/A |
INTRINSIC |
|
low complexity region
|
1477 |
1494 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195531
AA Change: D1690G
PolyPhen 2
Score 0.003 (Sensitivity: 0.98; Specificity: 0.44)
|
| SMART Domains |
Protein: ENSMUSP00000141920
Gene: ENSMUSG00000052613
AA Change: D1690G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
CA
|
64 |
145 |
6e-4 |
SMART |
|
CA
|
174 |
263 |
2.8e-10 |
SMART |
|
CA
|
304 |
393 |
9.4e-11 |
SMART |
|
CA
|
426 |
507 |
1.2e-12 |
SMART |
|
CA
|
531 |
613 |
2.3e-16 |
SMART |
|
CA
|
638 |
715 |
2.3e-22 |
SMART |
|
CA
|
739 |
817 |
9.3e-29 |
SMART |
|
CA
|
841 |
924 |
2.8e-17 |
SMART |
|
CA
|
948 |
1034 |
3.3e-11 |
SMART |
|
CA
|
1055 |
1142 |
1.5e-18 |
SMART |
|
CA
|
1166 |
1250 |
2.3e-6 |
SMART |
|
transmembrane domain
|
1377 |
1399 |
N/A |
INTRINSIC |
|
low complexity region
|
1415 |
1442 |
N/A |
INTRINSIC |
|
low complexity region
|
1514 |
1531 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193739
AA Change: D1653G
PolyPhen 2
Score 0.255 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000142173
Gene: ENSMUSG00000052613
AA Change: D1653G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
CA
|
69 |
150 |
1.22e-1 |
SMART |
|
CA
|
179 |
268 |
5.48e-8 |
SMART |
|
CA
|
309 |
398 |
1.94e-8 |
SMART |
|
CA
|
431 |
512 |
2.29e-10 |
SMART |
|
CA
|
536 |
618 |
4.88e-14 |
SMART |
|
CA
|
643 |
720 |
4.65e-20 |
SMART |
|
CA
|
744 |
822 |
1.93e-26 |
SMART |
|
CA
|
846 |
929 |
5.69e-15 |
SMART |
|
CA
|
953 |
1039 |
6.85e-9 |
SMART |
|
CA
|
1060 |
1147 |
3.09e-16 |
SMART |
|
CA
|
1171 |
1255 |
4.49e-4 |
SMART |
|
transmembrane domain
|
1382 |
1404 |
N/A |
INTRINSIC |
|
low complexity region
|
1420 |
1447 |
N/A |
INTRINSIC |
|
low complexity region
|
1477 |
1494 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000177107
AA Change: D1658G
PolyPhen 2
Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000135501
Gene: ENSMUSG00000052613
AA Change: D1658G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
CA
|
69 |
150 |
1.22e-1 |
SMART |
|
CA
|
179 |
268 |
5.48e-8 |
SMART |
|
CA
|
309 |
398 |
1.94e-8 |
SMART |
|
CA
|
431 |
512 |
2.29e-10 |
SMART |
|
CA
|
536 |
618 |
4.88e-14 |
SMART |
|
CA
|
643 |
720 |
4.65e-20 |
SMART |
|
CA
|
744 |
822 |
1.93e-26 |
SMART |
|
CA
|
846 |
929 |
5.69e-15 |
SMART |
|
CA
|
953 |
1039 |
6.85e-9 |
SMART |
|
CA
|
1060 |
1147 |
3.09e-16 |
SMART |
|
CA
|
1171 |
1255 |
4.49e-4 |
SMART |
|
transmembrane domain
|
1380 |
1402 |
N/A |
INTRINSIC |
|
low complexity region
|
1423 |
1450 |
N/A |
INTRINSIC |
|
low complexity region
|
1482 |
1499 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000191854
AA Change: D1653G
PolyPhen 2
Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)
|
| SMART Domains |
Protein: ENSMUSP00000141973
Gene: ENSMUSG00000052613
AA Change: D1653G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
CA
|
64 |
145 |
1.22e-1 |
SMART |
|
CA
|
174 |
263 |
5.48e-8 |
SMART |
|
CA
|
304 |
393 |
1.94e-8 |
SMART |
|
CA
|
426 |
507 |
2.29e-10 |
SMART |
|
CA
|
531 |
613 |
4.88e-14 |
SMART |
|
CA
|
638 |
715 |
4.65e-20 |
SMART |
|
CA
|
739 |
817 |
1.93e-26 |
SMART |
|
CA
|
841 |
924 |
5.69e-15 |
SMART |
|
CA
|
948 |
1034 |
6.85e-9 |
SMART |
|
CA
|
1055 |
1142 |
3.09e-16 |
SMART |
|
CA
|
1166 |
1250 |
4.49e-4 |
SMART |
|
transmembrane domain
|
1375 |
1397 |
N/A |
INTRINSIC |
|
low complexity region
|
1418 |
1445 |
N/A |
INTRINSIC |
|
low complexity region
|
1477 |
1494 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192370
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155701
|
| SMART Domains |
Protein: ENSMUSP00000135495
Gene: ENSMUSG00000052613
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
CA
|
64 |
145 |
1.22e-1 |
SMART |
|
CA
|
174 |
263 |
5.48e-8 |
SMART |
|
Blast:CA
|
304 |
330 |
2e-8 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000191709
|
| SMART Domains |
Protein: ENSMUSP00000142313
Gene: ENSMUSG00000052613
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
CA
|
69 |
150 |
1.22e-1 |
SMART |
|
CA
|
179 |
268 |
5.48e-8 |
SMART |
|
CA
|
309 |
398 |
1.94e-8 |
SMART |
|
CA
|
431 |
512 |
2.29e-10 |
SMART |
|
CA
|
536 |
618 |
4.88e-14 |
SMART |
|
CA
|
643 |
720 |
4.65e-20 |
SMART |
|
CA
|
744 |
822 |
1.93e-26 |
SMART |
|
CA
|
846 |
929 |
5.69e-15 |
SMART |
|
CA
|
953 |
1039 |
6.85e-9 |
SMART |
|
CA
|
1060 |
1147 |
3.09e-16 |
SMART |
|
CA
|
1171 |
1255 |
4.49e-4 |
SMART |
|
transmembrane domain
|
1380 |
1402 |
N/A |
INTRINSIC |
|
low complexity region
|
1423 |
1450 |
N/A |
INTRINSIC |
|
low complexity region
|
1480 |
1510 |
N/A |
INTRINSIC |
|
low complexity region
|
1512 |
1530 |
N/A |
INTRINSIC |
|
low complexity region
|
1583 |
1646 |
N/A |
INTRINSIC |
|
low complexity region
|
1672 |
1703 |
N/A |
INTRINSIC |
|
low complexity region
|
1719 |
1747 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152655
|
| SMART Domains |
Protein: ENSMUSP00000118201
Gene: ENSMUSG00000052613
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
CA
|
64 |
145 |
6e-4 |
SMART |
|
CA
|
174 |
263 |
2.8e-10 |
SMART |
|
CA
|
304 |
393 |
9.4e-11 |
SMART |
|
CA
|
426 |
507 |
1.2e-12 |
SMART |
|
CA
|
531 |
613 |
2.3e-16 |
SMART |
|
CA
|
638 |
726 |
3.4e-6 |
SMART |
|
low complexity region
|
783 |
846 |
N/A |
INTRINSIC |
|
low complexity region
|
872 |
903 |
N/A |
INTRINSIC |
|
low complexity region
|
919 |
947 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152819
|
| SMART Domains |
Protein: ENSMUSP00000123647
Gene: ENSMUSG00000052613
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
CA
|
64 |
145 |
1.22e-1 |
SMART |
|
CA
|
174 |
263 |
5.48e-8 |
SMART |
|
Blast:CA
|
304 |
363 |
1e-33 |
BLAST |
|
low complexity region
|
364 |
399 |
N/A |
INTRINSIC |
|
low complexity region
|
452 |
515 |
N/A |
INTRINSIC |
|
low complexity region
|
541 |
572 |
N/A |
INTRINSIC |
|
low complexity region
|
588 |
616 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193174
|
| SMART Domains |
Protein: ENSMUSP00000142238
Gene: ENSMUSG00000052613
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
CA
|
64 |
145 |
6e-4 |
SMART |
|
CA
|
174 |
263 |
2.8e-10 |
SMART |
|
CA
|
304 |
393 |
9.4e-11 |
SMART |
|
CA
|
426 |
514 |
3.8e-11 |
SMART |
|
CA
|
538 |
620 |
2.3e-16 |
SMART |
|
CA
|
645 |
722 |
2.3e-22 |
SMART |
|
CA
|
746 |
824 |
9.3e-29 |
SMART |
|
CA
|
848 |
931 |
2.8e-17 |
SMART |
|
CA
|
955 |
1041 |
3.3e-11 |
SMART |
|
CA
|
1062 |
1149 |
1.5e-18 |
SMART |
|
CA
|
1173 |
1257 |
2.3e-6 |
SMART |
|
transmembrane domain
|
1382 |
1404 |
N/A |
INTRINSIC |
|
low complexity region
|
1425 |
1452 |
N/A |
INTRINSIC |
|
low complexity region
|
1482 |
1512 |
N/A |
INTRINSIC |
|
low complexity region
|
1514 |
1532 |
N/A |
INTRINSIC |
|
low complexity region
|
1585 |
1648 |
N/A |
INTRINSIC |
|
low complexity region
|
1674 |
1705 |
N/A |
INTRINSIC |
|
low complexity region
|
1721 |
1749 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000151116
|
| SMART Domains |
Protein: ENSMUSP00000119662
Gene: ENSMUSG00000052613
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
CA
|
69 |
150 |
1.22e-1 |
SMART |
|
CA
|
179 |
268 |
5.48e-8 |
SMART |
|
CA
|
309 |
398 |
1.94e-8 |
SMART |
|
CA
|
431 |
519 |
7.87e-9 |
SMART |
|
CA
|
543 |
625 |
4.88e-14 |
SMART |
|
CA
|
650 |
727 |
4.65e-20 |
SMART |
|
CA
|
751 |
829 |
1.93e-26 |
SMART |
|
CA
|
853 |
936 |
5.69e-15 |
SMART |
|
CA
|
960 |
1046 |
6.85e-9 |
SMART |
|
CA
|
1067 |
1154 |
3.09e-16 |
SMART |
|
CA
|
1178 |
1262 |
4.49e-4 |
SMART |
|
transmembrane domain
|
1387 |
1409 |
N/A |
INTRINSIC |
|
low complexity region
|
1430 |
1457 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1519 |
N/A |
INTRINSIC |
|
low complexity region
|
1521 |
1539 |
N/A |
INTRINSIC |
|
low complexity region
|
1592 |
1655 |
N/A |
INTRINSIC |
|
low complexity region
|
1681 |
1712 |
N/A |
INTRINSIC |
|
low complexity region
|
1728 |
1756 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 94.7%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur. [provided by RefSeq, Dec 2008]
PHENOTYPE: Homozygotes for severe mutations exhibit circling, head-tossing, hyperactivity, impaired swimming and profound deafness. Mice have defects in cochlea and degeneration of hair cells, spiral ganglion cells and saccular macula. Females are poor mothers. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(11) : Gene trapped(2) Transgenic(1) Spontaneous(6) Chemically induced(2)
|
| Other mutations in this stock |
Total: 103 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 9330159F19Rik |
T |
A |
10: 29,097,902 (GRCm39) |
C100S |
probably damaging |
Het |
| Abcc8 |
C |
T |
7: 45,800,204 (GRCm39) |
R526H |
probably damaging |
Het |
| Acad10 |
G |
A |
5: 121,769,630 (GRCm39) |
P609S |
probably benign |
Het |
| Acod1 |
A |
T |
14: 103,288,775 (GRCm39) |
D95V |
probably damaging |
Het |
| Acsm5 |
A |
T |
7: 119,129,677 (GRCm39) |
I130F |
possibly damaging |
Het |
| Ago4 |
A |
T |
4: 126,410,864 (GRCm39) |
D208E |
probably damaging |
Het |
| Agrn |
A |
T |
4: 156,250,881 (GRCm39) |
|
probably null |
Het |
| Ankar |
A |
T |
1: 72,697,853 (GRCm39) |
I791K |
probably damaging |
Het |
| Ano10 |
A |
G |
9: 122,088,011 (GRCm39) |
V364A |
probably damaging |
Het |
| Arhgap9 |
T |
C |
10: 127,164,854 (GRCm39) |
|
probably null |
Het |
| Arsi |
G |
A |
18: 61,049,666 (GRCm39) |
C183Y |
probably damaging |
Het |
| Ascl2 |
T |
G |
7: 142,521,953 (GRCm39) |
E97A |
probably damaging |
Het |
| Bcl2a1a |
C |
T |
9: 88,839,506 (GRCm39) |
R135W |
probably damaging |
Het |
| Bms1 |
C |
T |
6: 118,368,114 (GRCm39) |
|
probably null |
Het |
| Bysl |
T |
A |
17: 47,915,260 (GRCm39) |
T163S |
probably benign |
Het |
| Card10 |
A |
G |
15: 78,664,473 (GRCm39) |
I821T |
probably benign |
Het |
| Cc2d2a |
A |
T |
5: 43,892,737 (GRCm39) |
Q1433L |
probably damaging |
Het |
| Cchcr1 |
T |
C |
17: 35,841,410 (GRCm39) |
S809P |
probably benign |
Het |
| Ccz1 |
G |
T |
5: 143,949,815 (GRCm39) |
T70K |
probably damaging |
Het |
| Cdc25c |
G |
C |
18: 34,871,292 (GRCm39) |
L275V |
probably damaging |
Het |
| Cep164 |
A |
T |
9: 45,686,547 (GRCm39) |
L729Q |
probably damaging |
Het |
| Clcn6 |
A |
G |
4: 148,101,951 (GRCm39) |
|
probably null |
Het |
| Clcn7 |
T |
A |
17: 25,374,420 (GRCm39) |
V507E |
probably damaging |
Het |
| Cracdl |
T |
C |
1: 37,664,381 (GRCm39) |
M506V |
probably benign |
Het |
| Ctso |
A |
C |
3: 81,840,041 (GRCm39) |
T24P |
probably damaging |
Het |
| Dis3l2 |
A |
T |
1: 86,917,980 (GRCm39) |
N543I |
probably benign |
Het |
| Dnah12 |
A |
T |
14: 26,491,907 (GRCm39) |
Y1114F |
possibly damaging |
Het |
| Emx1 |
A |
G |
6: 85,181,033 (GRCm39) |
D250G |
probably benign |
Het |
| Epha4 |
G |
A |
1: 77,488,339 (GRCm39) |
A47V |
possibly damaging |
Het |
| Fam149b |
A |
C |
14: 20,428,524 (GRCm39) |
N341T |
probably damaging |
Het |
| Fsip2 |
A |
G |
2: 82,782,001 (GRCm39) |
K62R |
probably damaging |
Het |
| Fsip2 |
T |
C |
2: 82,816,782 (GRCm39) |
S4172P |
probably benign |
Het |
| Gbp3 |
A |
G |
3: 142,276,343 (GRCm39) |
R480G |
probably benign |
Het |
| Get3 |
A |
G |
8: 85,746,395 (GRCm39) |
V151A |
possibly damaging |
Het |
| Gja8 |
T |
G |
3: 96,827,033 (GRCm39) |
T210P |
probably damaging |
Het |
| Gm5431 |
T |
A |
11: 48,779,536 (GRCm39) |
N740I |
probably benign |
Het |
| Gm9930 |
T |
C |
10: 9,410,446 (GRCm39) |
|
noncoding transcript |
Het |
| Gstt4 |
C |
T |
10: 75,650,959 (GRCm39) |
C221Y |
probably benign |
Het |
| Gzmg |
A |
T |
14: 56,395,832 (GRCm39) |
D42E |
probably benign |
Het |
| Hoxd12 |
G |
A |
2: 74,505,815 (GRCm39) |
A129T |
possibly damaging |
Het |
| Hs2st1 |
G |
A |
3: 144,275,691 (GRCm39) |
|
probably benign |
Het |
| Ifnlr1 |
G |
T |
4: 135,432,559 (GRCm39) |
D332Y |
probably damaging |
Het |
| Igsf10 |
T |
C |
3: 59,239,287 (GRCm39) |
D298G |
probably damaging |
Het |
| Irf1 |
T |
C |
11: 53,664,617 (GRCm39) |
V108A |
probably damaging |
Het |
| Jsrp1 |
C |
G |
10: 80,648,140 (GRCm39) |
S36T |
probably benign |
Het |
| Kcnq5 |
T |
A |
1: 21,576,006 (GRCm39) |
R233* |
probably null |
Het |
| Kif7 |
T |
C |
7: 79,352,012 (GRCm39) |
K917E |
probably damaging |
Het |
| Krt7 |
A |
C |
15: 101,310,538 (GRCm39) |
I62L |
probably benign |
Het |
| Lifr |
A |
G |
15: 7,196,397 (GRCm39) |
T194A |
probably benign |
Het |
| Ltbp2 |
T |
C |
12: 84,851,183 (GRCm39) |
|
probably null |
Het |
| Maco1 |
A |
G |
4: 134,531,699 (GRCm39) |
S657P |
probably damaging |
Het |
| Man2c1 |
A |
G |
9: 57,048,672 (GRCm39) |
|
probably null |
Het |
| Met |
T |
C |
6: 17,491,966 (GRCm39) |
S243P |
probably damaging |
Het |
| Mllt10 |
C |
A |
2: 18,069,935 (GRCm39) |
D30E |
possibly damaging |
Het |
| Mre11a |
A |
C |
9: 14,707,065 (GRCm39) |
|
probably null |
Het |
| Mroh9 |
A |
G |
1: 162,866,514 (GRCm39) |
S710P |
probably benign |
Het |
| Mvk |
C |
A |
5: 114,588,459 (GRCm39) |
Y116* |
probably null |
Het |
| Myh1 |
A |
G |
11: 67,096,423 (GRCm39) |
I301V |
probably benign |
Het |
| Ncf1 |
T |
C |
5: 134,254,552 (GRCm39) |
D184G |
probably damaging |
Het |
| Nxpe4 |
T |
C |
9: 48,304,533 (GRCm39) |
F207L |
probably damaging |
Het |
| Or2ag18 |
G |
T |
7: 106,405,168 (GRCm39) |
P167H |
probably damaging |
Het |
| Or2y1b |
T |
G |
11: 49,209,048 (GRCm39) |
L225R |
probably damaging |
Het |
| Or4k51 |
T |
A |
2: 111,584,661 (GRCm39) |
N22K |
probably benign |
Het |
| Or52b1 |
A |
T |
7: 104,978,817 (GRCm39) |
I194N |
probably damaging |
Het |
| Or5b24 |
T |
A |
19: 12,912,537 (GRCm39) |
M145K |
possibly damaging |
Het |
| Or5w14 |
T |
C |
2: 87,541,392 (GRCm39) |
N286S |
probably damaging |
Het |
| Pcdh1 |
G |
A |
18: 38,332,532 (GRCm39) |
T296M |
possibly damaging |
Het |
| Pcdha7 |
C |
A |
18: 37,107,786 (GRCm39) |
D270E |
probably damaging |
Het |
| Pgam1 |
C |
A |
19: 41,904,315 (GRCm39) |
S137R |
probably damaging |
Het |
| Pitpnm2 |
T |
C |
5: 124,274,389 (GRCm39) |
E240G |
probably damaging |
Het |
| Plce1 |
T |
G |
19: 38,748,498 (GRCm39) |
I1729S |
probably damaging |
Het |
| Plppr4 |
G |
T |
3: 117,125,355 (GRCm39) |
N161K |
probably damaging |
Het |
| Pramel27 |
G |
A |
4: 143,578,561 (GRCm39) |
V274I |
probably benign |
Het |
| Prkce |
T |
A |
17: 86,932,754 (GRCm39) |
I578N |
probably damaging |
Het |
| Prss58 |
A |
C |
6: 40,874,734 (GRCm39) |
S36A |
probably damaging |
Het |
| Ptprm |
T |
C |
17: 67,000,773 (GRCm39) |
H1128R |
probably damaging |
Het |
| Rgs9 |
T |
C |
11: 109,159,798 (GRCm39) |
Y178C |
probably benign |
Het |
| Rubcn |
T |
C |
16: 32,667,624 (GRCm39) |
N179S |
probably damaging |
Het |
| Sh3bp1 |
C |
T |
15: 78,795,706 (GRCm39) |
P612S |
probably damaging |
Het |
| Sh3bp5 |
G |
A |
14: 31,133,586 (GRCm39) |
T82M |
probably damaging |
Het |
| Shank2 |
A |
G |
7: 143,965,314 (GRCm39) |
Y974C |
probably damaging |
Het |
| Slc9c1 |
T |
C |
16: 45,365,099 (GRCm39) |
I144T |
possibly damaging |
Het |
| Slf2 |
T |
C |
19: 44,930,045 (GRCm39) |
I374T |
possibly damaging |
Het |
| Snx13 |
A |
G |
12: 35,188,080 (GRCm39) |
D786G |
probably benign |
Het |
| Spcs3 |
A |
G |
8: 54,976,389 (GRCm39) |
V151A |
possibly damaging |
Het |
| Sstr2 |
A |
T |
11: 113,515,749 (GRCm39) |
I223F |
probably damaging |
Het |
| Stac3 |
T |
C |
10: 127,339,787 (GRCm39) |
|
probably null |
Het |
| Tas1r2 |
A |
G |
4: 139,387,162 (GRCm39) |
N207S |
probably damaging |
Het |
| Tectb |
C |
G |
19: 55,169,431 (GRCm39) |
|
probably benign |
Het |
| Tgm5 |
T |
C |
2: 120,907,429 (GRCm39) |
E98G |
possibly damaging |
Het |
| Tktl2 |
A |
G |
8: 66,965,504 (GRCm39) |
E354G |
probably benign |
Het |
| Tmem94 |
G |
A |
11: 115,682,787 (GRCm39) |
R608H |
probably damaging |
Het |
| Tnrc6a |
G |
A |
7: 122,770,315 (GRCm39) |
V702I |
probably damaging |
Het |
| Trappc10 |
A |
G |
10: 78,047,357 (GRCm39) |
S380P |
possibly damaging |
Het |
| Trim24 |
G |
A |
6: 37,880,587 (GRCm39) |
|
probably null |
Het |
| Ugt1a2 |
A |
G |
1: 88,128,846 (GRCm39) |
Y163C |
probably damaging |
Het |
| Vmn1r215 |
A |
G |
13: 23,260,343 (GRCm39) |
I128V |
probably benign |
Het |
| Vmn2r50 |
T |
A |
7: 9,781,640 (GRCm39) |
E368D |
possibly damaging |
Het |
| Vmn2r59 |
T |
C |
7: 41,693,190 (GRCm39) |
N470S |
probably damaging |
Het |
| Vps45 |
T |
C |
3: 95,948,757 (GRCm39) |
T333A |
probably benign |
Het |
| Zbtb44 |
T |
A |
9: 30,965,539 (GRCm39) |
D316E |
probably damaging |
Het |
| Zdhhc1 |
C |
T |
8: 106,210,190 (GRCm39) |
V76M |
probably benign |
Het |
| Zfp235 |
T |
C |
7: 23,841,549 (GRCm39) |
F656S |
probably damaging |
Het |
|
| Other mutations in Pcdh15 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00421:Pcdh15
|
APN |
10 |
74,021,177 (GRCm39) |
nonsense |
probably null |
|
|
IGL00432:Pcdh15
|
APN |
10 |
74,126,914 (GRCm39) |
splice site |
probably benign |
|
|
IGL00533:Pcdh15
|
APN |
10 |
74,338,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00596:Pcdh15
|
APN |
10 |
74,466,576 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00930:Pcdh15
|
APN |
10 |
74,466,530 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL00970:Pcdh15
|
APN |
10 |
74,215,172 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01087:Pcdh15
|
APN |
10 |
74,178,464 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01763:Pcdh15
|
APN |
10 |
74,046,293 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01787:Pcdh15
|
APN |
10 |
74,286,115 (GRCm39) |
missense |
probably benign |
0.25 |
|
IGL02070:Pcdh15
|
APN |
10 |
74,466,700 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02234:Pcdh15
|
APN |
10 |
74,467,694 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02268:Pcdh15
|
APN |
10 |
74,178,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02280:Pcdh15
|
APN |
10 |
74,058,295 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02363:Pcdh15
|
APN |
10 |
74,152,918 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02420:Pcdh15
|
APN |
10 |
74,138,938 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02749:Pcdh15
|
APN |
10 |
74,466,900 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02939:Pcdh15
|
APN |
10 |
74,340,648 (GRCm39) |
splice site |
probably benign |
|
|
IGL02970:Pcdh15
|
APN |
10 |
74,126,794 (GRCm39) |
splice site |
probably benign |
|
|
IGL03010:Pcdh15
|
APN |
10 |
74,221,777 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03061:Pcdh15
|
APN |
10 |
74,152,843 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL03095:Pcdh15
|
APN |
10 |
74,191,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03149:Pcdh15
|
APN |
10 |
74,466,527 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03187:Pcdh15
|
APN |
10 |
74,191,706 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03279:Pcdh15
|
APN |
10 |
74,152,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03392:Pcdh15
|
APN |
10 |
74,460,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
loop
|
UTSW |
10 |
74,021,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
mcduck
|
UTSW |
10 |
74,462,676 (GRCm39) |
critical splice donor site |
probably null |
|
|
spaz
|
UTSW |
10 |
74,046,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
sphere
|
UTSW |
10 |
74,460,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
squirm
|
UTSW |
10 |
0 () |
large deletion |
|
|
|
Tortilla
|
UTSW |
10 |
74,215,249 (GRCm39) |
splice site |
probably null |
|
|
1mM(1):Pcdh15
|
UTSW |
10 |
74,461,969 (GRCm39) |
intron |
probably benign |
|
|
BB009:Pcdh15
|
UTSW |
10 |
74,481,359 (GRCm39) |
missense |
probably benign |
0.18 |
|
BB019:Pcdh15
|
UTSW |
10 |
74,481,359 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0038:Pcdh15
|
UTSW |
10 |
74,479,272 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0103:Pcdh15
|
UTSW |
10 |
74,046,257 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0110:Pcdh15
|
UTSW |
10 |
74,126,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0111:Pcdh15
|
UTSW |
10 |
74,462,651 (GRCm39) |
nonsense |
probably null |
|
|
R0119:Pcdh15
|
UTSW |
10 |
74,006,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0131:Pcdh15
|
UTSW |
10 |
74,006,440 (GRCm39) |
missense |
probably null |
1.00 |
|
R0445:Pcdh15
|
UTSW |
10 |
74,178,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0464:Pcdh15
|
UTSW |
10 |
74,462,676 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0503:Pcdh15
|
UTSW |
10 |
74,046,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0507:Pcdh15
|
UTSW |
10 |
74,457,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0510:Pcdh15
|
UTSW |
10 |
74,126,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0742:Pcdh15
|
UTSW |
10 |
74,457,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0790:Pcdh15
|
UTSW |
10 |
74,466,885 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0829:Pcdh15
|
UTSW |
10 |
74,338,598 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0839:Pcdh15
|
UTSW |
10 |
74,462,614 (GRCm39) |
missense |
probably null |
1.00 |
|
R0882:Pcdh15
|
UTSW |
10 |
74,178,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0894:Pcdh15
|
UTSW |
10 |
74,460,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0944:Pcdh15
|
UTSW |
10 |
74,046,302 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1081:Pcdh15
|
UTSW |
10 |
74,286,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1148:Pcdh15
|
UTSW |
10 |
74,006,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1148:Pcdh15
|
UTSW |
10 |
74,006,392 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1484:Pcdh15
|
UTSW |
10 |
74,126,833 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1521:Pcdh15
|
UTSW |
10 |
74,430,023 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1694:Pcdh15
|
UTSW |
10 |
74,429,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1795:Pcdh15
|
UTSW |
10 |
74,460,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2021:Pcdh15
|
UTSW |
10 |
74,467,025 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2022:Pcdh15
|
UTSW |
10 |
74,467,025 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2023:Pcdh15
|
UTSW |
10 |
74,467,025 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2076:Pcdh15
|
UTSW |
10 |
74,178,479 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2199:Pcdh15
|
UTSW |
10 |
74,006,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2510:Pcdh15
|
UTSW |
10 |
74,467,331 (GRCm39) |
missense |
probably benign |
0.39 |
|
R3418:Pcdh15
|
UTSW |
10 |
74,420,054 (GRCm39) |
missense |
probably benign |
0.12 |
|
R3419:Pcdh15
|
UTSW |
10 |
74,420,054 (GRCm39) |
missense |
probably benign |
0.12 |
|
R3433:Pcdh15
|
UTSW |
10 |
74,467,331 (GRCm39) |
missense |
probably benign |
0.39 |
|
R3619:Pcdh15
|
UTSW |
10 |
74,479,227 (GRCm39) |
missense |
probably benign |
0.19 |
|
R3723:Pcdh15
|
UTSW |
10 |
74,481,680 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3724:Pcdh15
|
UTSW |
10 |
74,481,680 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3778:Pcdh15
|
UTSW |
10 |
73,782,983 (GRCm39) |
splice site |
probably null |
|
|
R3851:Pcdh15
|
UTSW |
10 |
74,467,518 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4175:Pcdh15
|
UTSW |
10 |
74,467,829 (GRCm39) |
intron |
probably benign |
|
|
R4261:Pcdh15
|
UTSW |
10 |
74,481,512 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4385:Pcdh15
|
UTSW |
10 |
74,386,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4585:Pcdh15
|
UTSW |
10 |
74,460,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4602:Pcdh15
|
UTSW |
10 |
74,430,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4639:Pcdh15
|
UTSW |
10 |
74,479,439 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4703:Pcdh15
|
UTSW |
10 |
74,285,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4819:Pcdh15
|
UTSW |
10 |
74,160,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4906:Pcdh15
|
UTSW |
10 |
74,340,625 (GRCm39) |
nonsense |
probably null |
|
|
R4961:Pcdh15
|
UTSW |
10 |
74,215,249 (GRCm39) |
splice site |
probably null |
|
|
R5018:Pcdh15
|
UTSW |
10 |
74,479,607 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R5125:Pcdh15
|
UTSW |
10 |
74,419,912 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5225:Pcdh15
|
UTSW |
10 |
74,138,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5259:Pcdh15
|
UTSW |
10 |
74,232,204 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5279:Pcdh15
|
UTSW |
10 |
74,430,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5395:Pcdh15
|
UTSW |
10 |
74,021,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5458:Pcdh15
|
UTSW |
10 |
74,340,611 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5617:Pcdh15
|
UTSW |
10 |
74,471,504 (GRCm39) |
intron |
probably benign |
|
|
R5665:Pcdh15
|
UTSW |
10 |
74,462,620 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5770:Pcdh15
|
UTSW |
10 |
74,021,177 (GRCm39) |
nonsense |
probably null |
|
|
R5805:Pcdh15
|
UTSW |
10 |
74,066,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5914:Pcdh15
|
UTSW |
10 |
74,466,768 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5988:Pcdh15
|
UTSW |
10 |
74,215,189 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6133:Pcdh15
|
UTSW |
10 |
74,481,805 (GRCm39) |
splice site |
probably null |
|
|
R6189:Pcdh15
|
UTSW |
10 |
74,178,483 (GRCm39) |
missense |
probably null |
1.00 |
|
R6414:Pcdh15
|
UTSW |
10 |
74,021,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6536:Pcdh15
|
UTSW |
10 |
74,467,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6612:Pcdh15
|
UTSW |
10 |
74,021,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6711:Pcdh15
|
UTSW |
10 |
74,478,219 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6793:Pcdh15
|
UTSW |
10 |
74,466,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6841:Pcdh15
|
UTSW |
10 |
74,286,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6845:Pcdh15
|
UTSW |
10 |
74,466,465 (GRCm39) |
missense |
probably benign |
|
|
R6915:Pcdh15
|
UTSW |
10 |
74,479,641 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6954:Pcdh15
|
UTSW |
10 |
74,481,821 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6970:Pcdh15
|
UTSW |
10 |
74,338,519 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7018:Pcdh15
|
UTSW |
10 |
74,302,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7064:Pcdh15
|
UTSW |
10 |
74,466,446 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7079:Pcdh15
|
UTSW |
10 |
74,152,957 (GRCm39) |
missense |
probably benign |
0.21 |
|
R7172:Pcdh15
|
UTSW |
10 |
74,338,597 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7220:Pcdh15
|
UTSW |
10 |
74,178,441 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R7237:Pcdh15
|
UTSW |
10 |
74,420,023 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7266:Pcdh15
|
UTSW |
10 |
74,215,222 (GRCm39) |
nonsense |
probably null |
|
|
R7276:Pcdh15
|
UTSW |
10 |
74,160,224 (GRCm39) |
missense |
probably benign |
0.25 |
|
R7359:Pcdh15
|
UTSW |
10 |
74,420,048 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7396:Pcdh15
|
UTSW |
10 |
74,466,522 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7421:Pcdh15
|
UTSW |
10 |
74,289,897 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7424:Pcdh15
|
UTSW |
10 |
74,342,317 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7463:Pcdh15
|
UTSW |
10 |
74,467,602 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7469:Pcdh15
|
UTSW |
10 |
74,481,812 (GRCm39) |
missense |
probably benign |
|
|
R7512:Pcdh15
|
UTSW |
10 |
74,477,214 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7767:Pcdh15
|
UTSW |
10 |
74,322,088 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7830:Pcdh15
|
UTSW |
10 |
74,221,733 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7890:Pcdh15
|
UTSW |
10 |
74,478,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7897:Pcdh15
|
UTSW |
10 |
74,289,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7908:Pcdh15
|
UTSW |
10 |
74,479,414 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7932:Pcdh15
|
UTSW |
10 |
74,481,359 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7940:Pcdh15
|
UTSW |
10 |
74,430,022 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8230:Pcdh15
|
UTSW |
10 |
74,191,707 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8307:Pcdh15
|
UTSW |
10 |
74,342,307 (GRCm39) |
nonsense |
probably null |
|
|
R8382:Pcdh15
|
UTSW |
10 |
74,479,227 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8397:Pcdh15
|
UTSW |
10 |
74,126,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8498:Pcdh15
|
UTSW |
10 |
74,317,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8692:Pcdh15
|
UTSW |
10 |
74,289,805 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R8797:Pcdh15
|
UTSW |
10 |
74,419,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9020:Pcdh15
|
UTSW |
10 |
74,481,443 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9033:Pcdh15
|
UTSW |
10 |
74,302,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9056:Pcdh15
|
UTSW |
10 |
74,221,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9177:Pcdh15
|
UTSW |
10 |
74,479,455 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9191:Pcdh15
|
UTSW |
10 |
74,161,981 (GRCm39) |
missense |
probably benign |
0.38 |
|
R9268:Pcdh15
|
UTSW |
10 |
74,479,455 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9279:Pcdh15
|
UTSW |
10 |
74,461,756 (GRCm39) |
intron |
probably benign |
|
|
R9294:Pcdh15
|
UTSW |
10 |
74,479,560 (GRCm39) |
missense |
unknown |
|
|
R9387:Pcdh15
|
UTSW |
10 |
74,066,192 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9409:Pcdh15
|
UTSW |
10 |
74,160,190 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9410:Pcdh15
|
UTSW |
10 |
74,481,663 (GRCm39) |
frame shift |
probably null |
|
|
R9412:Pcdh15
|
UTSW |
10 |
74,481,663 (GRCm39) |
frame shift |
probably null |
|
|
R9432:Pcdh15
|
UTSW |
10 |
74,460,170 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9444:Pcdh15
|
UTSW |
10 |
74,478,176 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9579:Pcdh15
|
UTSW |
10 |
74,457,117 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9643:Pcdh15
|
UTSW |
10 |
74,479,335 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9784:Pcdh15
|
UTSW |
10 |
74,467,212 (GRCm39) |
missense |
probably benign |
0.00 |
|
RF020:Pcdh15
|
UTSW |
10 |
74,021,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Pcdh15
|
UTSW |
10 |
74,466,533 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Pcdh15
|
UTSW |
10 |
74,340,632 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
|
| Posted On |
2017-05-11 |
Incidental Mutation