Incidental Mutation 'R7201:Arhgef5'
| ID |
560297 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Arhgef5
|
| Ensembl Gene |
ENSMUSG00000033542 |
| Gene Name |
Rho guanine nucleotide exchange factor 5 |
| Synonyms |
2210412D05Rik |
| MMRRC Submission |
045279-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7201 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Validated
|
| Chromosome |
6 |
| Chromosomal Location |
43242578-43266254 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
C to T
at 43250166 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamine to Stop codon
at position 306
(Q306*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000031750
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000031750]
|
| AlphaFold |
E9Q7D5 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000031750
AA Change: Q306*
|
| SMART Domains |
Protein: ENSMUSP00000031750
Gene: ENSMUSG00000033542
AA Change: Q306*
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ARHGEF5_35
|
1 |
477 |
3.1e-220 |
PFAM |
|
low complexity region
|
509 |
531 |
N/A |
INTRINSIC |
|
low complexity region
|
812 |
825 |
N/A |
INTRINSIC |
|
low complexity region
|
827 |
851 |
N/A |
INTRINSIC |
|
RhoGEF
|
1162 |
1341 |
2.97e-57 |
SMART |
|
PH
|
1375 |
1488 |
1.11e-6 |
SMART |
|
SH3
|
1497 |
1554 |
6.39e-15 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000182924
|
| Meta Mutation Damage Score |
0.9701 |
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.8%
- 20x: 99.3%
|
| Validation Efficiency |
99% (80/81) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased Th2 response in an ovalbumin-induced asthma model. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acaca |
A |
G |
11: 84,153,300 (GRCm39) |
T903A |
probably benign |
Het |
| Acin1 |
A |
T |
14: 54,902,356 (GRCm39) |
S479T |
possibly damaging |
Het |
| Actr6 |
A |
T |
10: 89,548,374 (GRCm39) |
D370E |
probably benign |
Het |
| Adgrl3 |
T |
C |
5: 81,872,069 (GRCm39) |
F921S |
probably damaging |
Het |
| Ankmy1 |
A |
T |
1: 92,814,546 (GRCm39) |
H320Q |
possibly damaging |
Het |
| Art4 |
A |
T |
6: 136,831,547 (GRCm39) |
V198E |
probably benign |
Het |
| Asph |
G |
A |
4: 9,474,917 (GRCm39) |
R686W |
probably damaging |
Het |
| Atg7 |
A |
G |
6: 114,754,018 (GRCm39) |
H724R |
probably damaging |
Het |
| BC034090 |
A |
G |
1: 155,117,680 (GRCm39) |
V146A |
probably damaging |
Het |
| Bcl2a1d |
T |
A |
9: 88,613,639 (GRCm39) |
Q45L |
probably damaging |
Het |
| Bmal1 |
T |
A |
7: 112,884,349 (GRCm39) |
M122K |
probably damaging |
Het |
| Cd28 |
G |
T |
1: 60,802,332 (GRCm39) |
E84* |
probably null |
Het |
| Ceacam3 |
G |
A |
7: 16,892,163 (GRCm39) |
W302* |
probably null |
Het |
| Cerkl |
T |
C |
2: 79,163,934 (GRCm39) |
N462S |
probably benign |
Het |
| Cisd2 |
A |
T |
3: 135,116,974 (GRCm39) |
L39H |
probably damaging |
Het |
| Col11a1 |
C |
A |
3: 113,883,806 (GRCm39) |
T225K |
unknown |
Het |
| Col15a1 |
A |
T |
4: 47,307,752 (GRCm39) |
Y1178F |
possibly damaging |
Het |
| Cul4a |
T |
C |
8: 13,192,991 (GRCm39) |
S630P |
probably damaging |
Het |
| Cyp2c38 |
T |
A |
19: 39,390,220 (GRCm39) |
I327F |
probably damaging |
Het |
| Cyp3a25 |
A |
C |
5: 145,928,257 (GRCm39) |
S263A |
probably benign |
Het |
| Cyp3a25 |
T |
A |
5: 145,939,868 (GRCm39) |
L46F |
probably benign |
Het |
| Dmrta1 |
T |
A |
4: 89,580,408 (GRCm39) |
L456* |
probably null |
Het |
| Dnah12 |
T |
C |
14: 26,536,579 (GRCm39) |
L2165P |
probably benign |
Het |
| Dsg1a |
C |
A |
18: 20,461,368 (GRCm39) |
S253R |
probably damaging |
Het |
| Egln2 |
A |
C |
7: 26,859,744 (GRCm39) |
I323S |
probably damaging |
Het |
| Fam171b |
A |
G |
2: 83,708,574 (GRCm39) |
T359A |
probably damaging |
Het |
| Fcgr2b |
G |
T |
1: 170,790,966 (GRCm39) |
Q276K |
probably benign |
Het |
| Fcrl2 |
C |
T |
3: 87,159,934 (GRCm39) |
C440Y |
probably damaging |
Het |
| Fmnl2 |
T |
C |
2: 52,963,666 (GRCm39) |
V266A |
unknown |
Het |
| Glo1 |
A |
T |
17: 30,816,828 (GRCm39) |
D109E |
probably benign |
Het |
| Grin3b |
A |
G |
10: 79,809,912 (GRCm39) |
R473G |
possibly damaging |
Het |
| Ica1 |
G |
A |
6: 8,644,015 (GRCm39) |
L425F |
probably damaging |
Het |
| Iho1 |
A |
T |
9: 108,281,974 (GRCm39) |
D571E |
probably damaging |
Het |
| Ilrun |
A |
C |
17: 28,013,044 (GRCm39) |
|
probably null |
Het |
| Kcnq5 |
T |
C |
1: 21,473,099 (GRCm39) |
E716G |
possibly damaging |
Het |
| Klra17 |
A |
T |
6: 129,850,306 (GRCm39) |
I48K |
possibly damaging |
Het |
| Lrrc66 |
G |
T |
5: 73,787,240 (GRCm39) |
Q37K |
probably benign |
Het |
| Ly6a |
T |
A |
15: 74,868,325 (GRCm39) |
T55S |
probably benign |
Het |
| Lyst |
T |
A |
13: 13,883,885 (GRCm39) |
Y2924* |
probably null |
Het |
| Lyzl6 |
A |
G |
11: 103,522,177 (GRCm39) |
Y140H |
probably benign |
Het |
| Mak |
T |
C |
13: 41,204,916 (GRCm39) |
I141V |
possibly damaging |
Het |
| Mapk7 |
A |
G |
11: 61,379,998 (GRCm39) |
I789T |
probably benign |
Het |
| Mgat4f |
A |
G |
1: 134,318,206 (GRCm39) |
D326G |
possibly damaging |
Het |
| Mrpl4 |
T |
C |
9: 20,918,634 (GRCm39) |
I123T |
probably benign |
Het |
| Mup18 |
G |
C |
4: 61,591,573 (GRCm39) |
|
probably null |
Het |
| Myef2 |
T |
C |
2: 124,938,082 (GRCm39) |
|
probably null |
Het |
| Myh7 |
T |
C |
14: 55,228,402 (GRCm39) |
T235A |
possibly damaging |
Het |
| Myo18b |
C |
T |
5: 112,863,325 (GRCm39) |
C2171Y |
probably damaging |
Het |
| Nat8 |
A |
T |
6: 85,807,877 (GRCm39) |
Y85* |
probably null |
Het |
| Nyap1 |
A |
T |
5: 137,734,524 (GRCm39) |
S170T |
probably damaging |
Het |
| Ogfr |
AGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCAAAAGGCCAGGTGGAGCCAGAGGACCCAAAAGGCCAGGTGGGGCCAGAAGACCCAAAAGGCCAGGTGGGGCCAGAGGACCCAAAAGGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGGGGCCAGAG |
AGCCAGGTGGAGCCAGAGGACCCAAAAGGCCAGGTGGGGCCAGAAGACCCAAAAGGCCAGGTGGGGCCAGAGGACCCAAAAGGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGAGCCAGAGGACCCCAAAAGCCAGGTGGGGCCAGAGGACCCCCAAAGCCAGGTGGGGCCAGAG |
2: 180,236,887 (GRCm39) |
|
probably benign |
Het |
| Or10ah1-ps1 |
A |
G |
5: 143,123,553 (GRCm39) |
Y157H |
probably damaging |
Het |
| Or1e32 |
A |
G |
11: 73,705,167 (GRCm39) |
V247A |
probably benign |
Het |
| Or51a25 |
T |
A |
7: 102,373,692 (GRCm39) |
I2F |
probably benign |
Het |
| Papss1 |
T |
C |
3: 131,305,687 (GRCm39) |
L244P |
probably damaging |
Het |
| Pibf1 |
A |
T |
14: 99,433,844 (GRCm39) |
D597V |
probably damaging |
Het |
| Pmpcb |
T |
A |
5: 21,942,177 (GRCm39) |
M1K |
probably null |
Het |
| Ppwd1 |
G |
A |
13: 104,343,680 (GRCm39) |
P575L |
probably damaging |
Het |
| Pramel17 |
T |
A |
4: 101,695,338 (GRCm39) |
|
probably null |
Het |
| Prc1 |
A |
G |
7: 79,960,837 (GRCm39) |
Q457R |
possibly damaging |
Het |
| Prdm10 |
T |
C |
9: 31,227,602 (GRCm39) |
V69A |
possibly damaging |
Het |
| Prkdc |
A |
G |
16: 15,516,667 (GRCm39) |
I1014V |
probably benign |
Het |
| Rab3gap2 |
A |
G |
1: 184,999,388 (GRCm39) |
Y999C |
probably damaging |
Het |
| Robo3 |
G |
A |
9: 37,335,626 (GRCm39) |
Q539* |
probably null |
Het |
| Rps12 |
A |
G |
10: 23,661,129 (GRCm39) |
Y127H |
probably benign |
Het |
| Sar1b |
A |
G |
11: 51,679,079 (GRCm39) |
D116G |
probably benign |
Het |
| Selenbp2 |
C |
T |
3: 94,609,664 (GRCm39) |
P294L |
probably benign |
Het |
| Slc6a2 |
T |
C |
8: 93,722,300 (GRCm39) |
Y516H |
probably damaging |
Het |
| Slit2 |
A |
G |
5: 48,394,627 (GRCm39) |
N673S |
probably null |
Het |
| Snap91 |
A |
T |
9: 86,672,199 (GRCm39) |
|
probably null |
Het |
| Spata31h1 |
T |
C |
10: 82,127,461 (GRCm39) |
M1850V |
probably benign |
Het |
| Srpk2 |
A |
G |
5: 23,712,626 (GRCm39) |
F653L |
possibly damaging |
Het |
| Supt5 |
A |
T |
7: 28,016,213 (GRCm39) |
S824T |
probably benign |
Het |
| Taar7a |
A |
G |
10: 23,868,358 (GRCm39) |
V341A |
probably benign |
Het |
| Tmem52 |
G |
A |
4: 155,554,778 (GRCm39) |
G134R |
probably damaging |
Het |
| Ush2a |
A |
G |
1: 188,606,951 (GRCm39) |
T3949A |
probably benign |
Het |
| Usp32 |
GAACAAGTCCACAACAA |
GAACAA |
11: 84,913,681 (GRCm39) |
|
probably null |
Het |
| Vmn1r173 |
A |
T |
7: 23,401,583 (GRCm39) |
|
probably benign |
Het |
| Vmn2r118 |
G |
A |
17: 55,915,496 (GRCm39) |
R485* |
probably null |
Het |
| Vwce |
A |
G |
19: 10,615,479 (GRCm39) |
E120G |
possibly damaging |
Het |
| Zfp143 |
T |
C |
7: 109,692,287 (GRCm39) |
V566A |
possibly damaging |
Het |
|
| Other mutations in Arhgef5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00341:Arhgef5
|
APN |
6 |
43,257,203 (GRCm39) |
nonsense |
probably null |
|
|
IGL01341:Arhgef5
|
APN |
6 |
43,260,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01576:Arhgef5
|
APN |
6 |
43,250,962 (GRCm39) |
missense |
probably benign |
0.38 |
|
IGL01761:Arhgef5
|
APN |
6 |
43,251,538 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02104:Arhgef5
|
APN |
6 |
43,249,345 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02208:Arhgef5
|
APN |
6 |
43,252,064 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL02487:Arhgef5
|
APN |
6 |
43,260,916 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02650:Arhgef5
|
APN |
6 |
43,249,869 (GRCm39) |
nonsense |
probably null |
|
|
IGL03292:Arhgef5
|
APN |
6 |
43,257,180 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03334:Arhgef5
|
APN |
6 |
43,250,934 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL03341:Arhgef5
|
APN |
6 |
43,257,585 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0047:Arhgef5
|
UTSW |
6 |
43,242,555 (GRCm39) |
splice site |
probably null |
|
|
R0206:Arhgef5
|
UTSW |
6 |
43,250,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0208:Arhgef5
|
UTSW |
6 |
43,250,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0698:Arhgef5
|
UTSW |
6 |
43,250,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1145:Arhgef5
|
UTSW |
6 |
43,250,022 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1145:Arhgef5
|
UTSW |
6 |
43,250,022 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1168:Arhgef5
|
UTSW |
6 |
43,250,330 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1355:Arhgef5
|
UTSW |
6 |
43,260,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1370:Arhgef5
|
UTSW |
6 |
43,260,846 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1481:Arhgef5
|
UTSW |
6 |
43,251,568 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1529:Arhgef5
|
UTSW |
6 |
43,256,449 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1532:Arhgef5
|
UTSW |
6 |
43,250,337 (GRCm39) |
missense |
probably benign |
|
|
R1663:Arhgef5
|
UTSW |
6 |
43,253,899 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1742:Arhgef5
|
UTSW |
6 |
43,257,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1852:Arhgef5
|
UTSW |
6 |
43,252,119 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1869:Arhgef5
|
UTSW |
6 |
43,265,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1880:Arhgef5
|
UTSW |
6 |
43,250,022 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2146:Arhgef5
|
UTSW |
6 |
43,260,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2169:Arhgef5
|
UTSW |
6 |
43,251,354 (GRCm39) |
missense |
probably benign |
0.11 |
|
R3412:Arhgef5
|
UTSW |
6 |
43,250,724 (GRCm39) |
missense |
probably benign |
|
|
R4205:Arhgef5
|
UTSW |
6 |
43,250,766 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R4226:Arhgef5
|
UTSW |
6 |
43,256,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4227:Arhgef5
|
UTSW |
6 |
43,256,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4304:Arhgef5
|
UTSW |
6 |
43,256,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4308:Arhgef5
|
UTSW |
6 |
43,256,432 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4457:Arhgef5
|
UTSW |
6 |
43,251,027 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4469:Arhgef5
|
UTSW |
6 |
43,252,033 (GRCm39) |
missense |
probably benign |
|
|
R4636:Arhgef5
|
UTSW |
6 |
43,251,876 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4791:Arhgef5
|
UTSW |
6 |
43,260,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4818:Arhgef5
|
UTSW |
6 |
43,250,484 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4910:Arhgef5
|
UTSW |
6 |
43,249,762 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4911:Arhgef5
|
UTSW |
6 |
43,249,762 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5127:Arhgef5
|
UTSW |
6 |
43,250,148 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5209:Arhgef5
|
UTSW |
6 |
43,250,634 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5245:Arhgef5
|
UTSW |
6 |
43,242,614 (GRCm39) |
start gained |
probably benign |
|
|
R5251:Arhgef5
|
UTSW |
6 |
43,249,815 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R5513:Arhgef5
|
UTSW |
6 |
43,249,273 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5613:Arhgef5
|
UTSW |
6 |
43,250,997 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5616:Arhgef5
|
UTSW |
6 |
43,252,874 (GRCm39) |
missense |
probably benign |
0.20 |
|
R5817:Arhgef5
|
UTSW |
6 |
43,252,038 (GRCm39) |
missense |
probably benign |
0.15 |
|
R6024:Arhgef5
|
UTSW |
6 |
43,252,068 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6735:Arhgef5
|
UTSW |
6 |
43,251,966 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6825:Arhgef5
|
UTSW |
6 |
43,251,895 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6831:Arhgef5
|
UTSW |
6 |
43,257,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6901:Arhgef5
|
UTSW |
6 |
43,250,232 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6932:Arhgef5
|
UTSW |
6 |
43,251,351 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6968:Arhgef5
|
UTSW |
6 |
43,252,276 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7018:Arhgef5
|
UTSW |
6 |
43,265,665 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7180:Arhgef5
|
UTSW |
6 |
43,252,142 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7358:Arhgef5
|
UTSW |
6 |
43,256,507 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7359:Arhgef5
|
UTSW |
6 |
43,257,216 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7468:Arhgef5
|
UTSW |
6 |
43,257,605 (GRCm39) |
nonsense |
probably null |
|
|
R7503:Arhgef5
|
UTSW |
6 |
43,250,933 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7699:Arhgef5
|
UTSW |
6 |
43,251,691 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7700:Arhgef5
|
UTSW |
6 |
43,251,691 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7737:Arhgef5
|
UTSW |
6 |
43,250,728 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7847:Arhgef5
|
UTSW |
6 |
43,252,069 (GRCm39) |
nonsense |
probably null |
|
|
R7950:Arhgef5
|
UTSW |
6 |
43,250,859 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R8161:Arhgef5
|
UTSW |
6 |
43,260,885 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8178:Arhgef5
|
UTSW |
6 |
43,252,119 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8203:Arhgef5
|
UTSW |
6 |
43,257,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8318:Arhgef5
|
UTSW |
6 |
43,252,933 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8857:Arhgef5
|
UTSW |
6 |
43,264,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9499:Arhgef5
|
UTSW |
6 |
43,260,940 (GRCm39) |
missense |
|
|
|
R9610:Arhgef5
|
UTSW |
6 |
43,257,890 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9611:Arhgef5
|
UTSW |
6 |
43,257,890 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9623:Arhgef5
|
UTSW |
6 |
43,251,736 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9685:Arhgef5
|
UTSW |
6 |
43,250,527 (GRCm39) |
missense |
probably benign |
0.11 |
|
RF023:Arhgef5
|
UTSW |
6 |
43,256,407 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0028:Arhgef5
|
UTSW |
6 |
43,250,635 (GRCm39) |
missense |
probably benign |
0.03 |
|
X0065:Arhgef5
|
UTSW |
6 |
43,249,342 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCAATCTCAGGAAGCCCAGG -3'
(R):5'- ACGGGCATCACTTTTCCTG -3'
Sequencing Primer
(F):5'- AACTCTGAACGAAGGCATTTG -3'
(R):5'- GGCATCACTTTTCCTGTTTGATCATG -3'
|
| Posted On |
2019-06-26 |
Incidental Mutation