Incidental Mutation 'R0464:Mtus1'
| ID |
71429 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mtus1
|
| Ensembl Gene |
ENSMUSG00000045636 |
| Gene Name |
mitochondrial tumor suppressor 1 |
| Synonyms |
MTSG1, B430305I03Rik, MD44, Atip1 |
| MMRRC Submission |
038664-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.241)
|
| Stock # |
R0464 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
8 |
| Chromosomal Location |
41443951-41586763 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 41455511 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 56
(D56G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113082
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000051379]
[ENSMUST00000059115]
[ENSMUST00000093534]
[ENSMUST00000117735]
[ENSMUST00000118835]
[ENSMUST00000131965]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000051379
AA Change: D150G
PolyPhen 2
Score 0.815 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000053554
Gene: ENSMUSG00000045636
AA Change: D150G
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
106 |
168 |
N/A |
INTRINSIC |
|
coiled coil region
|
193 |
375 |
N/A |
INTRINSIC |
|
low complexity region
|
425 |
439 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000059115
AA Change: D920G
PolyPhen 2
Score 0.576 (Sensitivity: 0.88; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000059503
Gene: ENSMUSG00000045636
AA Change: D920G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
524 |
539 |
N/A |
INTRINSIC |
|
coiled coil region
|
876 |
938 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
1021 |
1156 |
3e-7 |
SMART |
|
low complexity region
|
1195 |
1209 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000093534
AA Change: D230G
PolyPhen 2
Score 0.815 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000091252
Gene: ENSMUSG00000045636
AA Change: D230G
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
186 |
248 |
N/A |
INTRINSIC |
|
coiled coil region
|
273 |
455 |
N/A |
INTRINSIC |
|
low complexity region
|
505 |
519 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000117735
AA Change: D56G
PolyPhen 2
Score 0.963 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000113082
Gene: ENSMUSG00000045636
AA Change: D56G
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
16 |
74 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000118835
AA Change: D920G
PolyPhen 2
Score 0.576 (Sensitivity: 0.88; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000112626
Gene: ENSMUSG00000045636
AA Change: D920G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
524 |
539 |
N/A |
INTRINSIC |
|
coiled coil region
|
876 |
938 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
1021 |
1156 |
3e-7 |
SMART |
|
low complexity region
|
1195 |
1209 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000131965
AA Change: D49G
PolyPhen 2
Score 0.936 (Sensitivity: 0.80; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000121605
Gene: ENSMUSG00000045636
AA Change: D49G
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
9 |
67 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000135194
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000155626
|
| Meta Mutation Damage Score |
0.6467 |
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.7%
- 10x: 97.3%
- 20x: 94.7%
|
| Validation Efficiency |
100% (80/80) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit spontaneous heart hypertrophy and SLE-like lymphoproliferative disease. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ada |
G |
T |
2: 163,574,884 (GRCm39) |
Y84* |
probably null |
Het |
| Adar |
T |
A |
3: 89,642,889 (GRCm39) |
C257S |
possibly damaging |
Het |
| Adgrd1 |
G |
T |
5: 129,239,714 (GRCm39) |
C507F |
probably damaging |
Het |
| Atp5f1a |
T |
C |
18: 77,867,622 (GRCm39) |
Y299H |
probably benign |
Het |
| Bok |
G |
T |
1: 93,621,935 (GRCm39) |
R77L |
probably damaging |
Het |
| Cdx2 |
C |
A |
5: 147,243,283 (GRCm39) |
K170N |
possibly damaging |
Het |
| Ceacam1 |
A |
G |
7: 25,171,442 (GRCm39) |
S341P |
possibly damaging |
Het |
| Cfhr3 |
A |
T |
1: 139,521,683 (GRCm39) |
|
noncoding transcript |
Het |
| Ckap5 |
A |
G |
2: 91,409,858 (GRCm39) |
I947V |
probably benign |
Het |
| Clec2i |
T |
C |
6: 128,872,386 (GRCm39) |
Y173H |
probably damaging |
Het |
| Cttnbp2 |
T |
C |
6: 18,408,690 (GRCm39) |
D977G |
possibly damaging |
Het |
| Cyp2f2 |
C |
A |
7: 26,831,962 (GRCm39) |
Q406K |
probably benign |
Het |
| Ddx28 |
A |
G |
8: 106,736,685 (GRCm39) |
S458P |
probably damaging |
Het |
| Dppa3 |
T |
A |
6: 122,605,492 (GRCm39) |
|
probably null |
Het |
| Dusp10 |
C |
A |
1: 183,801,273 (GRCm39) |
L347I |
probably benign |
Het |
| Fads1 |
C |
T |
19: 10,160,429 (GRCm39) |
P5L |
probably benign |
Het |
| Fbxl15 |
A |
T |
19: 46,316,951 (GRCm39) |
E13D |
probably benign |
Het |
| Fhit |
T |
A |
14: 10,991,567 (GRCm38) |
|
probably benign |
Het |
| Fras1 |
G |
T |
5: 96,784,662 (GRCm39) |
V882F |
probably damaging |
Het |
| G3bp1 |
T |
C |
11: 55,389,452 (GRCm39) |
F383L |
probably damaging |
Het |
| Gabbr1 |
C |
T |
17: 37,361,726 (GRCm39) |
|
probably benign |
Het |
| Ganc |
T |
A |
2: 120,267,175 (GRCm39) |
V497D |
probably benign |
Het |
| Glt8d2 |
T |
G |
10: 82,490,564 (GRCm39) |
H242P |
possibly damaging |
Het |
| Gna15 |
T |
C |
10: 81,348,338 (GRCm39) |
Y131C |
probably benign |
Het |
| Gpatch8 |
T |
C |
11: 102,371,712 (GRCm39) |
K609E |
unknown |
Het |
| Gprc5a |
A |
T |
6: 135,056,413 (GRCm39) |
K287* |
probably null |
Het |
| Iqub |
T |
A |
6: 24,479,262 (GRCm39) |
K427* |
probably null |
Het |
| Itpr2 |
C |
G |
6: 146,277,387 (GRCm39) |
D666H |
probably damaging |
Het |
| Kcnj5 |
T |
C |
9: 32,234,269 (GRCm39) |
I15M |
possibly damaging |
Het |
| Kcnn2 |
A |
G |
18: 45,693,426 (GRCm39) |
E334G |
probably damaging |
Het |
| Lypd6 |
T |
A |
2: 50,080,690 (GRCm39) |
I126N |
probably damaging |
Het |
| Ms4a20 |
A |
G |
19: 11,089,801 (GRCm39) |
L28P |
probably damaging |
Het |
| Myo1h |
A |
G |
5: 114,498,571 (GRCm39) |
D889G |
probably damaging |
Het |
| Myrf |
G |
C |
19: 10,195,526 (GRCm39) |
T428S |
probably benign |
Het |
| Nab1 |
T |
C |
1: 52,529,174 (GRCm39) |
D241G |
possibly damaging |
Het |
| Naip2 |
A |
C |
13: 100,298,290 (GRCm39) |
I582S |
probably benign |
Het |
| Ncbp3 |
C |
T |
11: 72,960,647 (GRCm39) |
|
probably benign |
Het |
| Nek1 |
T |
A |
8: 61,525,307 (GRCm39) |
|
probably benign |
Het |
| Nf1 |
T |
C |
11: 79,447,615 (GRCm39) |
V2452A |
probably benign |
Het |
| Nlrp1b |
A |
C |
11: 71,109,070 (GRCm39) |
S144A |
probably damaging |
Het |
| Npr2 |
A |
T |
4: 43,640,597 (GRCm39) |
|
probably null |
Het |
| Pak3 |
TTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC |
"TTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC,TTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCTC" |
X: 142,526,889 (GRCm39) |
|
probably benign |
Het |
| Paox |
T |
A |
7: 139,709,195 (GRCm39) |
|
probably benign |
Het |
| Pcdh15 |
T |
A |
10: 74,462,676 (GRCm39) |
|
probably null |
Het |
| Pde8b |
G |
A |
13: 95,241,206 (GRCm39) |
T202M |
probably damaging |
Het |
| Pigo |
A |
T |
4: 43,019,814 (GRCm39) |
V905D |
probably benign |
Het |
| Pik3cb |
A |
G |
9: 98,926,796 (GRCm39) |
|
probably null |
Het |
| Rassf5 |
T |
C |
1: 131,139,998 (GRCm39) |
N87S |
probably benign |
Het |
| Rbl1 |
C |
A |
2: 156,989,465 (GRCm39) |
K1051N |
probably damaging |
Het |
| Rfx7 |
T |
C |
9: 72,525,486 (GRCm39) |
V892A |
probably damaging |
Het |
| Ripply1 |
TTCCTCCTCCTCCTCCTCCTCCTCCTCCTCCT |
TTCCTCCTCCTCCTCCTCCTCCTCCTCCT |
X: 138,680,599 (GRCm39) |
|
probably benign |
Het |
| Rnf144b |
T |
A |
13: 47,396,363 (GRCm39) |
Y233* |
probably null |
Het |
| Safb |
C |
T |
17: 56,913,025 (GRCm39) |
R914C |
probably damaging |
Het |
| Sbf2 |
T |
C |
7: 110,063,783 (GRCm39) |
|
probably benign |
Het |
| Sgo2a |
A |
T |
1: 58,039,253 (GRCm39) |
K85N |
probably damaging |
Het |
| Siglec1 |
A |
T |
2: 130,921,279 (GRCm39) |
C631S |
probably damaging |
Het |
| Simc1 |
C |
T |
13: 54,684,913 (GRCm39) |
R50* |
probably null |
Het |
| Skint5 |
T |
A |
4: 113,392,928 (GRCm39) |
M1235L |
unknown |
Het |
| Slc22a19 |
A |
T |
19: 7,660,278 (GRCm39) |
N377K |
probably benign |
Het |
| Spata31d1a |
A |
G |
13: 59,849,573 (GRCm39) |
F852L |
possibly damaging |
Het |
| Spata31e3 |
A |
G |
13: 50,402,311 (GRCm39) |
|
probably benign |
Het |
| Srbd1 |
G |
A |
17: 86,427,430 (GRCm39) |
S401F |
probably damaging |
Het |
| Stk36 |
C |
A |
1: 74,650,331 (GRCm39) |
Q288K |
probably damaging |
Het |
| Styx |
T |
C |
14: 45,609,908 (GRCm39) |
S191P |
probably benign |
Het |
| Supt6 |
T |
A |
11: 78,107,164 (GRCm39) |
N1214I |
probably benign |
Het |
| Tcim |
T |
A |
8: 24,928,644 (GRCm39) |
D90V |
probably damaging |
Het |
| Tdpoz1 |
T |
A |
3: 93,578,782 (GRCm39) |
M1L |
probably damaging |
Het |
| Tep1 |
T |
A |
14: 51,085,141 (GRCm39) |
T881S |
probably benign |
Het |
| Tlr5 |
C |
T |
1: 182,801,275 (GRCm39) |
A193V |
probably benign |
Het |
| Tmem117 |
T |
A |
15: 94,612,800 (GRCm39) |
F112Y |
probably damaging |
Het |
| Tnrc6c |
C |
T |
11: 117,651,375 (GRCm39) |
R1633W |
probably damaging |
Het |
| Trh |
T |
C |
6: 92,220,649 (GRCm39) |
|
probably null |
Het |
| Triobp |
A |
G |
15: 78,851,186 (GRCm39) |
R447G |
possibly damaging |
Het |
| Trip6 |
A |
G |
5: 137,311,943 (GRCm39) |
F46S |
probably damaging |
Het |
| Ubxn4 |
G |
A |
1: 128,190,641 (GRCm39) |
E256K |
probably benign |
Het |
| Usp33 |
T |
C |
3: 152,081,872 (GRCm39) |
|
probably benign |
Het |
| Vmn2r60 |
A |
T |
7: 41,785,255 (GRCm39) |
I156F |
probably damaging |
Het |
| Wdr17 |
T |
C |
8: 55,123,427 (GRCm39) |
|
probably benign |
Het |
| Wdr35 |
G |
T |
12: 9,077,472 (GRCm39) |
|
probably benign |
Het |
| Wwp1 |
C |
T |
4: 19,638,763 (GRCm39) |
|
probably benign |
Het |
| Zfp652 |
T |
C |
11: 95,654,475 (GRCm39) |
C293R |
probably damaging |
Het |
|
| Other mutations in Mtus1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00708:Mtus1
|
APN |
8 |
41,537,386 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01377:Mtus1
|
APN |
8 |
41,536,172 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01472:Mtus1
|
APN |
8 |
41,455,449 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01995:Mtus1
|
APN |
8 |
41,537,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02027:Mtus1
|
APN |
8 |
41,446,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02381:Mtus1
|
APN |
8 |
41,536,156 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02571:Mtus1
|
APN |
8 |
41,536,519 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02936:Mtus1
|
APN |
8 |
41,452,554 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0116:Mtus1
|
UTSW |
8 |
41,451,514 (GRCm39) |
unclassified |
probably benign |
|
|
R0139:Mtus1
|
UTSW |
8 |
41,469,233 (GRCm39) |
splice site |
probably benign |
|
|
R0178:Mtus1
|
UTSW |
8 |
41,455,398 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0179:Mtus1
|
UTSW |
8 |
41,455,398 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0220:Mtus1
|
UTSW |
8 |
41,447,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0324:Mtus1
|
UTSW |
8 |
41,537,432 (GRCm39) |
missense |
probably benign |
|
|
R0355:Mtus1
|
UTSW |
8 |
41,535,965 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0357:Mtus1
|
UTSW |
8 |
41,536,563 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R0681:Mtus1
|
UTSW |
8 |
41,446,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1016:Mtus1
|
UTSW |
8 |
41,503,063 (GRCm39) |
missense |
probably benign |
0.43 |
|
R1570:Mtus1
|
UTSW |
8 |
41,529,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1579:Mtus1
|
UTSW |
8 |
41,535,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1607:Mtus1
|
UTSW |
8 |
41,468,446 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1869:Mtus1
|
UTSW |
8 |
41,529,267 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1888:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1888:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1891:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1894:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2063:Mtus1
|
UTSW |
8 |
41,535,745 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2111:Mtus1
|
UTSW |
8 |
41,475,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2112:Mtus1
|
UTSW |
8 |
41,475,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2224:Mtus1
|
UTSW |
8 |
41,535,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2226:Mtus1
|
UTSW |
8 |
41,535,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2227:Mtus1
|
UTSW |
8 |
41,535,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2516:Mtus1
|
UTSW |
8 |
41,535,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3414:Mtus1
|
UTSW |
8 |
41,501,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3899:Mtus1
|
UTSW |
8 |
41,536,166 (GRCm39) |
missense |
probably benign |
|
|
R4096:Mtus1
|
UTSW |
8 |
41,537,284 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4831:Mtus1
|
UTSW |
8 |
41,536,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4850:Mtus1
|
UTSW |
8 |
41,537,507 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4916:Mtus1
|
UTSW |
8 |
41,453,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4940:Mtus1
|
UTSW |
8 |
41,494,515 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R4988:Mtus1
|
UTSW |
8 |
41,537,578 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5133:Mtus1
|
UTSW |
8 |
41,536,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5468:Mtus1
|
UTSW |
8 |
41,537,615 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5598:Mtus1
|
UTSW |
8 |
41,475,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5782:Mtus1
|
UTSW |
8 |
41,535,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5860:Mtus1
|
UTSW |
8 |
41,529,303 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5900:Mtus1
|
UTSW |
8 |
41,536,534 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5943:Mtus1
|
UTSW |
8 |
41,537,302 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6019:Mtus1
|
UTSW |
8 |
41,536,077 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6125:Mtus1
|
UTSW |
8 |
41,537,576 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6197:Mtus1
|
UTSW |
8 |
41,537,074 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6488:Mtus1
|
UTSW |
8 |
41,494,545 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R6869:Mtus1
|
UTSW |
8 |
41,535,691 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7117:Mtus1
|
UTSW |
8 |
41,536,621 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7126:Mtus1
|
UTSW |
8 |
41,468,439 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7213:Mtus1
|
UTSW |
8 |
41,537,524 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7308:Mtus1
|
UTSW |
8 |
41,535,965 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7424:Mtus1
|
UTSW |
8 |
41,475,443 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7481:Mtus1
|
UTSW |
8 |
41,537,652 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7485:Mtus1
|
UTSW |
8 |
41,537,590 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7660:Mtus1
|
UTSW |
8 |
41,469,248 (GRCm39) |
missense |
probably benign |
|
|
R7699:Mtus1
|
UTSW |
8 |
41,537,006 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7700:Mtus1
|
UTSW |
8 |
41,537,006 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7709:Mtus1
|
UTSW |
8 |
41,507,687 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7791:Mtus1
|
UTSW |
8 |
41,536,417 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8196:Mtus1
|
UTSW |
8 |
41,509,689 (GRCm39) |
missense |
probably benign |
|
|
R8463:Mtus1
|
UTSW |
8 |
41,536,271 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8724:Mtus1
|
UTSW |
8 |
41,451,500 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9047:Mtus1
|
UTSW |
8 |
41,536,760 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9092:Mtus1
|
UTSW |
8 |
41,455,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9283:Mtus1
|
UTSW |
8 |
41,536,519 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9313:Mtus1
|
UTSW |
8 |
41,535,923 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9329:Mtus1
|
UTSW |
8 |
41,537,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9603:Mtus1
|
UTSW |
8 |
41,536,795 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9711:Mtus1
|
UTSW |
8 |
41,536,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACAGCATCTAGAACGGCAGCAG -3'
(R):5'- TAAGGTCCACCACCATCCTTTGGC -3'
Sequencing Primer
(F):5'- TAGAACGGCAGCAGACAGC -3'
(R):5'- GGAGCCTCCTTTGATGGAC -3'
|
| Posted On |
2013-09-30 |
Incidental Mutation