Incidental Mutation 'IGL01869:Vmn1r192'
| ID |
178638 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r192
|
| Ensembl Gene |
ENSMUSG00000099787 |
| Gene Name |
vomeronasal 1 receptor 192 |
| Synonyms |
V1ri1 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.065)
|
| Stock # |
IGL01869
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
13 |
| Chromosomal Location |
22371316-22372218 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 22371750 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Tyrosine
at position 157
(N157Y)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000072426
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072632]
|
| AlphaFold |
Q8K4C9 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000072632
AA Change: N157Y
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000072426
Gene: ENSMUSG00000099787
AA Change: N157Y
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TAS2R
|
1 |
293 |
2.6e-10 |
PFAM |
|
Pfam:V1R
|
37 |
299 |
1.1e-35 |
PFAM |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 33 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700026F02Rik |
A |
G |
8: 71,495,689 (GRCm39) |
|
noncoding transcript |
Het |
| Adam29 |
T |
C |
8: 56,324,732 (GRCm39) |
H574R |
probably damaging |
Het |
| Arap1 |
C |
A |
7: 101,049,490 (GRCm39) |
T984K |
probably damaging |
Het |
| Ccdc146 |
A |
T |
5: 21,521,837 (GRCm39) |
S396T |
probably benign |
Het |
| Col6a3 |
T |
C |
1: 90,700,770 (GRCm39) |
K2587E |
unknown |
Het |
| Cyp3a44 |
A |
G |
5: 145,727,496 (GRCm39) |
S278P |
probably damaging |
Het |
| Daw1 |
T |
G |
1: 83,159,965 (GRCm39) |
|
probably benign |
Het |
| Dnah17 |
T |
C |
11: 117,943,502 (GRCm39) |
K3200R |
probably benign |
Het |
| Efhd2 |
A |
G |
4: 141,601,913 (GRCm39) |
F89S |
probably damaging |
Het |
| Fras1 |
A |
G |
5: 96,856,642 (GRCm39) |
|
probably benign |
Het |
| Ggps1 |
T |
C |
13: 14,228,979 (GRCm39) |
D68G |
probably damaging |
Het |
| Gm10718 |
A |
T |
9: 3,025,118 (GRCm39) |
Y194F |
probably benign |
Het |
| Gm21738 |
G |
A |
14: 19,416,979 (GRCm38) |
S144L |
probably benign |
Het |
| Gm3604 |
A |
T |
13: 62,517,954 (GRCm39) |
C134S |
probably damaging |
Het |
| Gpaa1 |
A |
G |
15: 76,217,198 (GRCm39) |
T178A |
probably benign |
Het |
| Lama3 |
A |
G |
18: 12,657,820 (GRCm39) |
N312S |
possibly damaging |
Het |
| Npepps |
T |
C |
11: 97,126,948 (GRCm39) |
I437M |
probably damaging |
Het |
| Or10q12 |
A |
G |
19: 13,746,534 (GRCm39) |
D276G |
probably benign |
Het |
| Or11i1 |
C |
T |
3: 106,729,342 (GRCm39) |
D178N |
probably benign |
Het |
| Rcor1 |
C |
A |
12: 111,070,193 (GRCm39) |
T330K |
possibly damaging |
Het |
| Sbno2 |
A |
G |
10: 79,896,226 (GRCm39) |
|
probably null |
Het |
| Sema3g |
A |
G |
14: 30,945,624 (GRCm39) |
E478G |
probably damaging |
Het |
| Smg9 |
A |
G |
7: 24,115,949 (GRCm39) |
D280G |
probably damaging |
Het |
| Smtnl1 |
A |
T |
2: 84,641,741 (GRCm39) |
*460R |
probably null |
Het |
| Syde1 |
A |
G |
10: 78,424,753 (GRCm39) |
C360R |
possibly damaging |
Het |
| Szt2 |
A |
G |
4: 118,256,268 (GRCm39) |
V197A |
possibly damaging |
Het |
| Tnrc6c |
T |
C |
11: 117,646,274 (GRCm39) |
V1405A |
possibly damaging |
Het |
| Ttbk1 |
A |
G |
17: 46,757,989 (GRCm39) |
S882P |
probably damaging |
Het |
| Tubgcp4 |
T |
A |
2: 121,006,269 (GRCm39) |
H116Q |
possibly damaging |
Het |
| Vmn1r60 |
C |
T |
7: 5,547,228 (GRCm39) |
V291M |
probably benign |
Het |
| Vmn2r129 |
C |
T |
4: 156,690,549 (GRCm39) |
|
noncoding transcript |
Het |
| Xpo5 |
C |
T |
17: 46,553,133 (GRCm39) |
P1184L |
possibly damaging |
Het |
| Zfp946 |
T |
G |
17: 22,673,684 (GRCm39) |
I146S |
probably benign |
Het |
|
| Other mutations in Vmn1r192 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01410:Vmn1r192
|
APN |
13 |
22,372,079 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0975:Vmn1r192
|
UTSW |
13 |
22,371,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1751:Vmn1r192
|
UTSW |
13 |
22,371,441 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1767:Vmn1r192
|
UTSW |
13 |
22,371,441 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1880:Vmn1r192
|
UTSW |
13 |
22,371,764 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1881:Vmn1r192
|
UTSW |
13 |
22,371,764 (GRCm39) |
missense |
probably benign |
0.12 |
|
R2113:Vmn1r192
|
UTSW |
13 |
22,371,800 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4290:Vmn1r192
|
UTSW |
13 |
22,371,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4292:Vmn1r192
|
UTSW |
13 |
22,371,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4294:Vmn1r192
|
UTSW |
13 |
22,371,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4295:Vmn1r192
|
UTSW |
13 |
22,371,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4921:Vmn1r192
|
UTSW |
13 |
22,371,650 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5377:Vmn1r192
|
UTSW |
13 |
22,371,801 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5569:Vmn1r192
|
UTSW |
13 |
22,371,384 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6181:Vmn1r192
|
UTSW |
13 |
22,371,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6455:Vmn1r192
|
UTSW |
13 |
22,372,000 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6860:Vmn1r192
|
UTSW |
13 |
22,372,122 (GRCm39) |
missense |
probably benign |
|
|
R7246:Vmn1r192
|
UTSW |
13 |
22,371,944 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7762:Vmn1r192
|
UTSW |
13 |
22,371,845 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8066:Vmn1r192
|
UTSW |
13 |
22,371,565 (GRCm39) |
nonsense |
probably null |
|
|
R8378:Vmn1r192
|
UTSW |
13 |
22,372,029 (GRCm39) |
nonsense |
probably null |
|
|
R9075:Vmn1r192
|
UTSW |
13 |
22,371,333 (GRCm39) |
missense |
probably benign |
|
|
R9206:Vmn1r192
|
UTSW |
13 |
22,371,401 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9208:Vmn1r192
|
UTSW |
13 |
22,371,401 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9313:Vmn1r192
|
UTSW |
13 |
22,372,191 (GRCm39) |
missense |
probably benign |
0.38 |
|
R9367:Vmn1r192
|
UTSW |
13 |
22,371,800 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R9694:Vmn1r192
|
UTSW |
13 |
22,372,119 (GRCm39) |
missense |
probably benign |
|
|
R9760:Vmn1r192
|
UTSW |
13 |
22,372,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Posted On |
2014-05-07 |
Incidental Mutation