Incidental Mutation 'IGL02190:Tuba1c'
ID283828
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tuba1c
Ensembl Gene ENSMUSG00000043091
Gene Nametubulin, alpha 1C
SynonymsTuba6, M[a]6
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL02190
Quality Score
Status
Chromosome15
Chromosomal Location99029891-99038110 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to A at 99037989 bp
ZygosityHeterozygous
Amino Acid Change Aspartic acid to Asparagine at position 444 (D444N)
Ref Sequence ENSEMBL: ENSMUSP00000051033 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000058914]
Predicted Effect unknown
Transcript: ENSMUST00000058914
AA Change: D444N
SMART Domains Protein: ENSMUSP00000051033
Gene: ENSMUSG00000043091
AA Change: D444N

DomainStartEndE-ValueType
Tubulin 49 246 6.98e-83 SMART
Tubulin_C 248 393 9.05e-59 SMART
low complexity region 433 448 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000230447
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 39 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adgrd1 T C 5: 129,140,724 probably benign Het
AI314180 A T 4: 58,800,190 S1838R probably benign Het
Ano1 T C 7: 144,618,883 E521G probably benign Het
As3mt A T 19: 46,719,945 I224F probably benign Het
Atp5j2 C A 5: 145,183,832 probably benign Het
Cacna1h A G 17: 25,433,026 V48A probably benign Het
Ctu2 T C 8: 122,481,658 probably benign Het
Efcab5 T C 11: 77,121,314 R841G probably benign Het
Erbb3 A T 10: 128,571,010 probably null Het
Fkbp15 G T 4: 62,304,822 P947T possibly damaging Het
Gabpb1 A G 2: 126,653,549 probably benign Het
Gcn1l1 G T 5: 115,614,124 V2100L probably damaging Het
Gemin5 A C 11: 58,134,842 V977G probably damaging Het
Gpr107 T A 2: 31,178,320 Y265N probably damaging Het
Gpx8 T C 13: 113,043,309 probably benign Het
H2-Eb2 A T 17: 34,334,374 N178I probably damaging Het
Ift172 C T 5: 31,254,458 V1587I possibly damaging Het
Lrrc45 A G 11: 120,718,508 T398A probably damaging Het
Mmrn1 G T 6: 60,987,193 V1059L probably benign Het
Morn5 A G 2: 36,079,515 D147G probably benign Het
Mphosph9 T C 5: 124,265,425 R847G possibly damaging Het
Nutm1 C T 2: 112,249,406 W721* probably null Het
Olfr1136 A G 2: 87,693,063 M273T probably benign Het
Olfr347 T C 2: 36,734,579 L86P probably benign Het
Olfr531 T C 7: 140,400,120 probably benign Het
Rgl3 A G 9: 21,981,708 F227L probably benign Het
Ropn1l G T 15: 31,443,341 L182I probably benign Het
Ror2 C T 13: 53,110,728 S764N probably damaging Het
Scgb1a1 A T 19: 9,087,867 L12Q probably damaging Het
Scp2 A G 4: 108,087,128 S237P probably benign Het
Skint5 T C 4: 113,940,765 Q207R possibly damaging Het
Slc16a5 A G 11: 115,462,609 M1V probably null Het
Tox2 G A 2: 163,323,006 R522H possibly damaging Het
Trip12 A T 1: 84,766,070 N505K probably damaging Het
Vmn1r174 A G 7: 23,754,827 E306G unknown Het
Vmn2r111 A T 17: 22,570,773 F417L probably benign Het
Vmn2r15 A T 5: 109,293,374 M206K probably damaging Het
Vmn2r95 G T 17: 18,451,776 A592S probably benign Het
Zfp318 C T 17: 46,396,810 R265* probably null Het
Other mutations in Tuba1c
AlleleSourceChrCoordTypePredicted EffectPPH Score
R2261:Tuba1c UTSW 15 99037876 missense probably damaging 1.00
R2262:Tuba1c UTSW 15 99037876 missense probably damaging 1.00
R4939:Tuba1c UTSW 15 99037954 missense probably damaging 1.00
R6367:Tuba1c UTSW 15 99037453 missense probably damaging 1.00
R6397:Tuba1c UTSW 15 99037857 missense probably benign 0.29
R6999:Tuba1c UTSW 15 99037312 missense probably benign 0.00
R8146:Tuba1c UTSW 15 99037615 missense probably damaging 1.00
R8186:Tuba1c UTSW 15 99037515 missense probably benign
R8403:Tuba1c UTSW 15 99034104 missense probably damaging 0.98
Posted On2015-04-16