Incidental Mutation 'IGL02307:Gm10260'
ID287624
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm10260
Ensembl Gene ENSMUSG00000069117
Gene Namepredicted gene 10260
Synonyms
Accession Numbers
Is this an essential gene? Possibly non essential (E-score: 0.422) question?
Stock #IGL02307
Quality Score
Status
Chromosome13
Chromosomal Location97760072-97760632 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to T at 97760363 bp
ZygosityHeterozygous
Amino Acid Change Glutamine to Lysine at position 76 (Q76K)
Ref Sequence ENSEMBL: ENSMUSP00000126892 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000074072]
Predicted Effect probably benign
Transcript: ENSMUST00000074072
AA Change: Q76K

PolyPhen 2 Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
SMART Domains Protein: ENSMUSP00000126892
Gene: ENSMUSG00000069117
AA Change: Q76K

DomainStartEndE-ValueType
Pfam:Ribosomal_S13 14 142 2.3e-58 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000180396
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 53 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca4 A G 3: 122,141,746 D323G probably damaging Het
Ankrd28 A G 14: 31,733,708 C417R probably damaging Het
Astn1 C T 1: 158,674,614 R1133C probably damaging Het
Bdp1 C A 13: 100,093,438 G256V probably damaging Het
Cald1 A G 6: 34,753,455 K252E probably damaging Het
Ccdc141 T C 2: 77,029,342 E985G probably damaging Het
Ccdc144b T C 3: 36,018,867 K422R possibly damaging Het
Cdc23 A G 18: 34,641,389 I279T possibly damaging Het
Col16a1 C T 4: 130,059,009 P416L probably damaging Het
Coro1a T C 7: 126,701,564 D197G probably damaging Het
Ctnnd2 C T 15: 30,647,211 T351I possibly damaging Het
Fam76b A G 9: 13,844,036 N313S probably damaging Het
Fbxw20 C A 9: 109,233,533 W75L possibly damaging Het
Gjd2 T C 2: 114,011,913 T28A possibly damaging Het
Glyctk A C 9: 106,155,764 L350R possibly damaging Het
Gm20726 A T 14: 54,632,603 V237D probably damaging Het
Gpr22 C A 12: 31,708,740 C461F possibly damaging Het
Grhl2 A G 15: 37,288,288 T279A probably damaging Het
Gstm3 G A 3: 107,967,613 R108C probably damaging Het
Haus6 T C 4: 86,583,835 T600A possibly damaging Het
Htra4 G A 8: 25,033,694 A285V probably damaging Het
Igkv14-100 C T 6: 68,519,365 P81S probably damaging Het
Kif24 T G 4: 41,395,274 Q533P probably benign Het
Klhl1 A T 14: 96,201,373 N496K possibly damaging Het
Lama3 G T 18: 12,581,783 R1667L probably benign Het
Lct T A 1: 128,286,590 H1815L possibly damaging Het
Mrgprb2 T A 7: 48,552,896 Y27F probably benign Het
Mrpl15 A T 1: 4,783,953 H86Q possibly damaging Het
Myo10 C T 15: 25,776,315 probably benign Het
Nrp1 T C 8: 128,502,720 L893P probably damaging Het
Olfr570 A T 7: 102,900,879 N171Y probably benign Het
Olfr733 A C 14: 50,298,838 I157S probably damaging Het
Ovol1 T A 19: 5,553,615 D86V possibly damaging Het
Pacs2 T A 12: 113,070,773 M851K probably damaging Het
Pde1a A T 2: 79,906,068 M39K possibly damaging Het
Pdpn T C 4: 143,273,980 H94R possibly damaging Het
Plcg2 T A 8: 117,579,896 probably null Het
Pzp A T 6: 128,489,086 Y1210* probably null Het
Rnf148 G T 6: 23,654,891 S35R probably benign Het
Ros1 A T 10: 52,128,438 S1008T possibly damaging Het
Sis A T 3: 72,911,834 probably benign Het
Spag9 T A 11: 94,102,160 probably null Het
Srbd1 A G 17: 86,126,188 L327P probably damaging Het
Steap3 A T 1: 120,241,660 Y264* probably null Het
Swap70 A G 7: 110,281,294 E572G probably benign Het
Traf7 C A 17: 24,513,046 C193F possibly damaging Het
Trmt11 T C 10: 30,594,154 D58G possibly damaging Het
Tsc22d1 T C 14: 76,416,461 S127P probably damaging Het
Usf1 T A 1: 171,415,746 S30R probably damaging Het
Ush1c A G 7: 46,197,188 probably benign Het
Utrn A T 10: 12,750,065 L124* probably null Het
Vmn2r75 T C 7: 86,165,766 N173S probably benign Het
Zic2 T C 14: 122,476,634 V320A possibly damaging Het
Other mutations in Gm10260
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02165:Gm10260 APN 13 97760140 missense probably benign 0.03
R0537:Gm10260 UTSW 13 97760563 missense probably benign 0.01
R1673:Gm10260 UTSW 13 97760360 missense possibly damaging 0.90
R1831:Gm10260 UTSW 13 97760545 missense probably benign 0.02
R5888:Gm10260 UTSW 13 97760393 nonsense probably null
Posted On2015-04-16