Incidental Mutation 'IGL02733:Lce1k'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Lce1k
Ensembl Gene ENSMUSG00000095870
Gene Namelate cornified envelope 1K
SynonymsGm7055, Sprrl6
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.149) question?
Stock #IGL02733
Quality Score
Chromosomal Location92806291-92807891 bp(-) (GRCm38)
Type of Mutationutr 5 prime
DNA Base Change (assembly) T to A at 92806885 bp
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000137052 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000179917]
AlphaFold J3QP15
Predicted Effect probably benign
Transcript: ENSMUST00000179917
SMART Domains Protein: ENSMUSP00000137052
Gene: ENSMUSG00000095870

Pfam:LCE 22 62 3e-10 PFAM
Pfam:LCE 59 125 1.9e-12 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 34 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Acnat1 T A 4: 49,447,793 T245S probably benign Het
Agl T C 3: 116,780,997 I718V probably benign Het
Cbs T A 17: 31,625,031 N209Y probably benign Het
Cd163 T C 6: 124,325,341 C955R probably damaging Het
Dnajb3 A G 1: 88,204,940 probably benign Het
Dopey2 G A 16: 93,739,191 R59Q possibly damaging Het
Dtx1 A G 5: 120,681,435 L566P probably damaging Het
Fam198a A G 9: 121,965,028 R83G probably benign Het
Fgf14 G T 14: 123,983,801 P197Q probably damaging Het
Gcc1 G A 6: 28,420,662 Q66* probably null Het
Gypc T C 18: 32,559,826 probably benign Het
Helz2 G A 2: 181,235,026 A1225V probably benign Het
Herc1 A G 9: 66,450,992 T2452A probably benign Het
Hoxc4 A G 15: 103,034,726 I2V probably benign Het
Impa1 A G 3: 10,328,965 I14T probably benign Het
Itih1 T A 14: 30,936,720 D400V probably damaging Het
Lama3 T C 18: 12,578,127 Y3206H probably damaging Het
Mcpt4 C T 14: 56,060,667 M142I probably benign Het
Myo15b A G 11: 115,884,250 E2168G probably benign Het
Myom3 G T 4: 135,814,303 E1402* probably null Het
Nfyb G T 10: 82,755,033 Q55K probably damaging Het
Nobox T C 6: 43,307,202 K137E possibly damaging Het
Pnlip T A 19: 58,680,788 D406E probably benign Het
Pole A T 5: 110,312,728 probably benign Het
Ppp2r2b T C 18: 42,648,728 Y336C possibly damaging Het
Prkg1 T C 19: 31,302,301 T178A probably damaging Het
Prr11 C T 11: 87,103,545 A92T possibly damaging Het
Racgap1 G T 15: 99,639,704 S67R probably damaging Het
Scn10a G A 9: 119,616,705 P1462S probably damaging Het
Sptbn1 T C 11: 30,197,747 E29G probably benign Het
Srrm1 G A 4: 135,325,104 P658L unknown Het
Vmn2r72 T A 7: 85,751,813 T133S probably benign Het
Zbtb20 A G 16: 43,609,933 H269R possibly damaging Het
Zwilch A T 9: 64,146,836 N526K probably benign Het
Other mutations in Lce1k
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL03019:Lce1k APN 3 92806779 missense unknown
R1990:Lce1k UTSW 3 92806818 missense unknown
R1991:Lce1k UTSW 3 92806818 missense unknown
R1992:Lce1k UTSW 3 92806818 missense unknown
R2024:Lce1k UTSW 3 92806502 missense unknown
R2065:Lce1k UTSW 3 92806857 nonsense probably null
R2361:Lce1k UTSW 3 92806584 missense unknown
R2906:Lce1k UTSW 3 92806575 missense unknown
R4688:Lce1k UTSW 3 92806644 missense unknown
R4902:Lce1k UTSW 3 92806827 missense unknown
R7405:Lce1k UTSW 3 92806874 start codon destroyed probably null
R8917:Lce1k UTSW 3 92806790 missense unknown
Posted On2015-04-16