Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03007:Tex101'

407609

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tex101

Ensembl Gene

ENSMUSG00000062773

Gene Name

testis expressed gene 101

Synonyms

1700008H15Rik, TES101RP

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL03007

Quality Score

Status

Chromosome

Chromosomal Location

24367437-24371475 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

G to A at 24369906 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000146082 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000078001] [ENSMUST00000205488] [ENSMUST00000206390]

AlphaFold

Q9JMI7

Predicted Effect

probably benign
Transcript: ENSMUST00000078001

SMART Domains

Protein: ENSMUSP00000077150
Gene: ENSMUSG00000062773

Domain	Start	End	E-Value	Type
signal peptide	1	25	N/A	INTRINSIC
Pfam:UPAR_LY6	141	217	3.9e-15	PFAM
low complexity region	232	246	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000205488

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000206367

Predicted Effect

probably benign
Transcript: ENSMUST00000206390

Coding Region Coverage

Validation Efficiency

MGI Phenotype

PHENOTYPE: Male mice homozygous for a knockout allele of this marker are infertile due to the failure of sperm to migrate into the oviduct. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 35 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
9330159F19Rik	A	G	10: 29,098,034 (GRCm39)	N144D	possibly damaging	Het
A830031A19Rik	T	C	11: 23,999,248 (GRCm39)		probably benign	Het
Ankfy1	T	C	11: 72,641,347 (GRCm39)	F640S	probably damaging	Het
Asb8	A	G	15: 98,040,615 (GRCm39)	Y16H	probably damaging	Het
Astn1	T	C	1: 158,496,193 (GRCm39)		probably benign	Het
Btbd8	T	A	5: 107,651,542 (GRCm39)	V145E	probably benign	Het
Celf3	A	G	3: 94,394,444 (GRCm39)	T183A	probably benign	Het
Dctn1	T	C	6: 83,159,690 (GRCm39)	V56A	probably damaging	Het
Erbb2	A	C	11: 98,319,819 (GRCm39)		probably benign	Het
Ighv6-4	A	T	12: 114,370,213 (GRCm39)	Y80N	possibly damaging	Het
Igsf9b	T	C	9: 27,244,378 (GRCm39)	S782P	probably damaging	Het
Itsn1	A	T	16: 91,581,050 (GRCm39)		probably benign	Het
Kcnt2	T	A	1: 140,282,245 (GRCm39)	Y77N	possibly damaging	Het
Lig3	T	C	11: 82,680,401 (GRCm39)	F359S	probably damaging	Het
Mtmr6	G	T	14: 60,526,984 (GRCm39)		probably benign	Het
Muc4	C	T	16: 32,570,866 (GRCm39)	S642F	possibly damaging	Het
Ncoa1	T	A	12: 4,389,114 (GRCm39)	I54F	possibly damaging	Het
Nfx1	C	A	4: 40,984,962 (GRCm39)	T362K	probably benign	Het
Ntrk1	T	C	3: 87,690,050 (GRCm39)	S449G	possibly damaging	Het
Odc1	T	A	12: 17,598,811 (GRCm39)	H230Q	probably benign	Het
Or10d4	T	C	9: 39,580,767 (GRCm39)	V138A	possibly damaging	Het
Or10h28	A	G	17: 33,487,857 (GRCm39)	E53G	probably damaging	Het
Or1j19	T	C	2: 36,676,812 (GRCm39)	S92P	probably damaging	Het
Or8d1	C	T	9: 38,766,592 (GRCm39)	T78I	probably damaging	Het
Plekhh2	A	C	17: 84,882,388 (GRCm39)	S665R	possibly damaging	Het
Qpct	T	A	17: 79,378,294 (GRCm39)	F155I	probably damaging	Het
Rcor2	C	A	19: 7,251,718 (GRCm39)	T379K	probably benign	Het
Rint1	A	G	5: 24,020,699 (GRCm39)	N574S	probably benign	Het
Rsbn1	C	T	3: 103,836,195 (GRCm39)	A411V	probably damaging	Het
Sbno2	A	T	10: 79,894,384 (GRCm39)		probably benign	Het
Sptb	A	G	12: 76,668,115 (GRCm39)	S661P	probably damaging	Het
Syn3	A	T	10: 85,900,778 (GRCm39)	M370K	possibly damaging	Het
Tmem255b	C	T	8: 13,507,066 (GRCm39)	T265I	possibly damaging	Het
Trio	G	T	15: 27,902,828 (GRCm39)	A211D	probably damaging	Het
Zfp638	C	A	6: 83,961,866 (GRCm39)	Q1902K	probably damaging	Het

Other mutations in Tex101

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02313:Tex101	APN	7	24,367,750 (GRCm39)	missense	probably damaging	1.00
IGL03357:Tex101	APN	7	24,367,758 (GRCm39)	missense	probably damaging	0.96
R1935:Tex101	UTSW	7	24,367,650 (GRCm39)	missense	probably benign	0.33
R1936:Tex101	UTSW	7	24,367,650 (GRCm39)	missense	probably benign	0.33
R4632:Tex101	UTSW	7	24,367,793 (GRCm39)	nonsense	probably null
R6109:Tex101	UTSW	7	24,367,738 (GRCm39)	missense	possibly damaging	0.79
R7049:Tex101	UTSW	7	24,367,683 (GRCm39)	missense	probably benign	0.03
R7276:Tex101	UTSW	7	24,369,829 (GRCm39)	missense	probably damaging	1.00
R7860:Tex101	UTSW	7	24,369,190 (GRCm39)	missense	probably damaging	1.00
R8092:Tex101	UTSW	7	24,369,778 (GRCm39)	missense	probably damaging	1.00
R8435:Tex101	UTSW	7	24,367,791 (GRCm39)	missense	probably damaging	1.00
R8514:Tex101	UTSW	7	24,367,957 (GRCm39)	missense	possibly damaging	0.87

Posted On

2016-08-02