Incidental Mutation 'IGL03179:Olfr568'
ID412156
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Olfr568
Ensembl Gene ENSMUSG00000073965
Gene Nameolfactory receptor 568
SynonymsMOR14-3, MOR14-11, GA_x6K02T2PBJ9-5588278-5589228
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.112) question?
Stock #IGL03179
Quality Score
Status
Chromosome7
Chromosomal Location102877122-102878063 bp(+) (GRCm38)
Type of Mutationunclassified
DNA Base Change (assembly) T to C at 102878072 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000095818 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000098216]
Predicted Effect probably benign
Transcript: ENSMUST00000098216
SMART Domains Protein: ENSMUSP00000095818
Gene: ENSMUSG00000073965

DomainStartEndE-ValueType
Pfam:7tm_4 32 309 7.6e-113 PFAM
Pfam:7TM_GPCR_Srsx 34 306 1.8e-7 PFAM
Pfam:7tm_1 40 291 1e-20 PFAM
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4932429P05Rik G A X: 89,752,828 G89S possibly damaging Het
AI314180 C T 4: 58,832,777 G861D probably damaging Het
Akap11 T A 14: 78,507,740 H1736L probably benign Het
App A G 16: 85,082,847 C133R probably damaging Het
Atxn7l2 G T 3: 108,203,647 C524* probably null Het
Cckbr T C 7: 105,434,923 V288A probably benign Het
Ccr1l1 T C 9: 123,977,750 Y220C probably damaging Het
Cdc42se2 A T 11: 54,723,591 F47I possibly damaging Het
Cep290 T A 10: 100,568,088 I2317N possibly damaging Het
Chrnd T C 1: 87,195,780 S347P probably damaging Het
Clcn5 T A X: 7,163,326 probably null Het
D6Wsu163e A G 6: 126,950,111 D187G probably damaging Het
Dnajc13 T A 9: 104,167,435 I1852F probably benign Het
Fcnb A G 2: 28,076,634 S296P possibly damaging Het
Fut2 C T 7: 45,650,649 R233K probably benign Het
Gm21985 G A 2: 112,358,555 V1078I possibly damaging Het
Gpc3 A T X: 52,397,213 probably benign Het
Krt10 A G 11: 99,389,218 probably benign Het
Lrrk2 A G 15: 91,700,578 E370G probably damaging Het
Myo5c A T 9: 75,255,866 I326F possibly damaging Het
Neb A T 2: 52,176,641 L5906Q probably damaging Het
Nrd1 A T 4: 109,046,691 probably benign Het
Nrip2 A G 6: 128,404,975 N17S possibly damaging Het
Olfr750 T C 14: 51,071,010 I128V probably benign Het
P2rx7 A G 5: 122,673,700 Y358C possibly damaging Het
Pex10 A C 4: 155,067,897 I61L probably benign Het
Phax T C 18: 56,580,292 F248L probably damaging Het
Phtf2 A T 5: 20,782,399 D366E probably damaging Het
Pnpo A G 11: 96,939,259 Y205H possibly damaging Het
Pparg T A 6: 115,439,872 W9R probably damaging Het
Prex1 C T 2: 166,585,194 S867N probably benign Het
Pyroxd2 T A 19: 42,747,562 N59I possibly damaging Het
Rnf135 T A 11: 80,194,011 S203R possibly damaging Het
Sall1 T A 8: 89,031,661 N605I probably benign Het
Scara3 C T 14: 65,931,154 R338H probably damaging Het
Slc25a14 T C X: 48,637,440 S152P probably benign Het
Strip1 A T 3: 107,620,255 F436I probably damaging Het
Tgfa T C 6: 86,271,421 L135P probably benign Het
Tgif1 T C 17: 70,844,947 Q170R possibly damaging Het
Tmc2 G A 2: 130,229,187 E279K probably damaging Het
Tnks G T 8: 34,848,670 N987K probably benign Het
Traf3ip3 T C 1: 193,194,368 E209G probably damaging Het
Vmn2r73 T A 7: 85,870,260 I497L probably benign Het
Wrn C A 8: 33,310,706 probably null Het
Zcchc24 T C 14: 25,719,662 I193V possibly damaging Het
Other mutations in Olfr568
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01682:Olfr568 APN 7 102877233 missense probably benign 0.02
IGL02349:Olfr568 APN 7 102877909 missense probably benign 0.06
IGL02421:Olfr568 APN 7 102877759 missense probably damaging 1.00
FR4737:Olfr568 UTSW 7 102877233 small insertion probably benign
R0003:Olfr568 UTSW 7 102877861 missense probably benign 0.02
R0126:Olfr568 UTSW 7 102877140 missense probably benign 0.25
R1435:Olfr568 UTSW 7 102877767 missense probably damaging 1.00
R1585:Olfr568 UTSW 7 102877773 missense probably benign 0.00
R1660:Olfr568 UTSW 7 102877656 missense probably damaging 1.00
R1678:Olfr568 UTSW 7 102877663 missense probably damaging 1.00
R2010:Olfr568 UTSW 7 102877685 nonsense probably null
R4706:Olfr568 UTSW 7 102877433 missense probably damaging 1.00
R5490:Olfr568 UTSW 7 102877893 missense probably damaging 1.00
R5632:Olfr568 UTSW 7 102877797 missense probably benign 0.00
R6370:Olfr568 UTSW 7 102877170 missense probably benign 0.43
R6675:Olfr568 UTSW 7 102877273 missense possibly damaging 0.89
R7854:Olfr568 UTSW 7 102877785 nonsense probably null
R7937:Olfr568 UTSW 7 102877785 nonsense probably null
Posted On2016-08-02