Incidental Mutation 'IGL01022:Gm10800'
| ID |
53465 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Gm10800
|
| Ensembl Gene |
ENSMUSG00000075014 |
| Gene Name |
predicted gene 10800 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.285)
|
| Stock # |
IGL01022
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
2 |
| Chromosomal Location |
98496892-98497646 bp(-) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
T to A
at 98497576 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000097276
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000099683]
[ENSMUST00000099684]
|
| AlphaFold |
D3Z496 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000099683
|
| SMART Domains |
Protein: ENSMUSP00000097275
Gene: ENSMUSG00000075014
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
1 |
41 |
1.13e-5 |
PROSPERO |
|
internal_repeat_2
|
26 |
49 |
4.11e-5 |
PROSPERO |
|
transmembrane domain
|
78 |
96 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
114 |
174 |
1.13e-5 |
PROSPERO |
|
low complexity region
|
177 |
188 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
197 |
219 |
4.11e-5 |
PROSPERO |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000099684
|
| SMART Domains |
Protein: ENSMUSP00000097276
Gene: ENSMUSG00000075015
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
2 |
73 |
1.19e-13 |
PROSPERO |
|
internal_repeat_1
|
80 |
167 |
1.19e-13 |
PROSPERO |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 29 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamts14 |
A |
G |
10: 61,038,721 (GRCm39) |
S927P |
probably benign |
Het |
| Arfgef1 |
G |
T |
1: 10,244,301 (GRCm39) |
F987L |
probably damaging |
Het |
| Asph |
A |
T |
4: 9,601,344 (GRCm39) |
N191K |
possibly damaging |
Het |
| Bmpr1b |
A |
T |
3: 141,577,099 (GRCm39) |
C71S |
probably damaging |
Het |
| Bod1l |
A |
T |
5: 41,951,652 (GRCm39) |
S2920T |
probably damaging |
Het |
| Camta2 |
G |
A |
11: 70,562,308 (GRCm39) |
R1030* |
probably null |
Het |
| Chd8 |
T |
C |
14: 52,474,450 (GRCm39) |
T194A |
probably benign |
Het |
| Col9a3 |
A |
T |
2: 180,258,227 (GRCm39) |
I549F |
probably damaging |
Het |
| Fstl4 |
A |
G |
11: 53,077,568 (GRCm39) |
N775S |
probably benign |
Het |
| Gm5117 |
T |
A |
8: 32,228,515 (GRCm39) |
|
noncoding transcript |
Het |
| Hap1 |
A |
G |
11: 100,240,374 (GRCm39) |
L112P |
probably benign |
Het |
| Hcls1 |
C |
A |
16: 36,771,488 (GRCm39) |
|
probably benign |
Het |
| Kmt2c |
A |
G |
5: 25,507,699 (GRCm39) |
|
probably benign |
Het |
| Lct |
T |
A |
1: 128,228,596 (GRCm39) |
I966L |
probably benign |
Het |
| Myo1h |
A |
T |
5: 114,474,361 (GRCm39) |
I451F |
possibly damaging |
Het |
| Notch4 |
G |
A |
17: 34,784,671 (GRCm39) |
C128Y |
probably damaging |
Het |
| Oca2 |
T |
A |
7: 55,974,504 (GRCm39) |
N484K |
probably damaging |
Het |
| Or51f1e |
T |
G |
7: 102,747,077 (GRCm39) |
L43R |
probably damaging |
Het |
| Or7a42 |
A |
T |
10: 78,791,188 (GRCm39) |
I50F |
possibly damaging |
Het |
| Rprd2 |
T |
A |
3: 95,671,066 (GRCm39) |
R1362* |
probably null |
Het |
| Sema3a |
C |
T |
5: 13,523,433 (GRCm39) |
T134I |
probably damaging |
Het |
| Sfta2 |
C |
T |
17: 35,961,336 (GRCm39) |
T74I |
possibly damaging |
Het |
| Slfn10-ps |
C |
T |
11: 82,926,353 (GRCm39) |
|
noncoding transcript |
Het |
| Spag11a |
A |
T |
8: 19,208,005 (GRCm39) |
Q15H |
probably damaging |
Het |
| Tbc1d22a |
G |
A |
15: 86,185,756 (GRCm39) |
D282N |
probably damaging |
Het |
| Tmbim6 |
G |
A |
15: 99,300,003 (GRCm39) |
V40M |
possibly damaging |
Het |
| Tmem259 |
A |
G |
10: 79,819,808 (GRCm39) |
V22A |
probably damaging |
Het |
| Tnik |
T |
C |
3: 28,679,377 (GRCm39) |
|
probably null |
Het |
| Unc13c |
T |
C |
9: 73,424,610 (GRCm39) |
D2002G |
probably benign |
Het |
|
| Other mutations in Gm10800 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
BB012:Gm10800
|
UTSW |
2 |
98,497,378 (GRCm39) |
frame shift |
probably null |
|
|
FR4976:Gm10800
|
UTSW |
2 |
98,497,378 (GRCm39) |
frame shift |
probably null |
|
|
PIT4131001:Gm10800
|
UTSW |
2 |
98,497,250 (GRCm39) |
missense |
probably benign |
|
|
PIT4131001:Gm10800
|
UTSW |
2 |
98,497,163 (GRCm39) |
missense |
probably benign |
|
|
PIT4131001:Gm10800
|
UTSW |
2 |
98,496,893 (GRCm39) |
missense |
probably benign |
0.11 |
|
PIT4142001:Gm10800
|
UTSW |
2 |
98,497,250 (GRCm39) |
missense |
probably benign |
|
|
PIT4142001:Gm10800
|
UTSW |
2 |
98,497,163 (GRCm39) |
missense |
probably benign |
|
|
PIT4142001:Gm10800
|
UTSW |
2 |
98,496,893 (GRCm39) |
missense |
probably benign |
0.11 |
|
PIT4142001:Gm10800
|
UTSW |
2 |
98,497,361 (GRCm39) |
frame shift |
probably null |
|
|
PIT4402001:Gm10800
|
UTSW |
2 |
98,497,361 (GRCm39) |
frame shift |
probably null |
|
|
PIT4498001:Gm10800
|
UTSW |
2 |
98,497,361 (GRCm39) |
frame shift |
probably null |
|
|
R0025:Gm10800
|
UTSW |
2 |
98,496,925 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5077:Gm10800
|
UTSW |
2 |
98,497,379 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5687:Gm10800
|
UTSW |
2 |
98,496,965 (GRCm39) |
missense |
probably benign |
|
|
R7146:Gm10800
|
UTSW |
2 |
98,497,378 (GRCm39) |
frame shift |
probably null |
|
|
R7206:Gm10800
|
UTSW |
2 |
98,497,378 (GRCm39) |
frame shift |
probably null |
|
|
R7619:Gm10800
|
UTSW |
2 |
98,497,378 (GRCm39) |
frame shift |
probably null |
|
|
R7930:Gm10800
|
UTSW |
2 |
98,497,379 (GRCm39) |
unclassified |
probably benign |
|
|
R7931:Gm10800
|
UTSW |
2 |
98,497,379 (GRCm39) |
unclassified |
probably benign |
|
|
R7998:Gm10800
|
UTSW |
2 |
98,497,378 (GRCm39) |
frame shift |
probably null |
|
|
R8019:Gm10800
|
UTSW |
2 |
98,497,378 (GRCm39) |
frame shift |
probably null |
|
|
R8110:Gm10800
|
UTSW |
2 |
98,497,361 (GRCm39) |
frame shift |
probably null |
|
|
R8111:Gm10800
|
UTSW |
2 |
98,497,361 (GRCm39) |
frame shift |
probably null |
|
|
R8488:Gm10800
|
UTSW |
2 |
98,497,379 (GRCm39) |
unclassified |
probably benign |
|
|
R8509:Gm10800
|
UTSW |
2 |
98,497,379 (GRCm39) |
unclassified |
probably benign |
|
|
R8692:Gm10800
|
UTSW |
2 |
98,497,379 (GRCm39) |
unclassified |
probably benign |
|
|
R8722:Gm10800
|
UTSW |
2 |
98,497,379 (GRCm39) |
unclassified |
probably benign |
|
|
R8789:Gm10800
|
UTSW |
2 |
98,497,361 (GRCm39) |
frame shift |
probably null |
|
|
R8902:Gm10800
|
UTSW |
2 |
98,497,361 (GRCm39) |
frame shift |
probably null |
|
|
R8903:Gm10800
|
UTSW |
2 |
98,497,361 (GRCm39) |
frame shift |
probably null |
|
|
R8935:Gm10800
|
UTSW |
2 |
98,497,378 (GRCm39) |
frame shift |
probably null |
|
|
R9104:Gm10800
|
UTSW |
2 |
98,497,379 (GRCm39) |
unclassified |
probably benign |
|
|
R9571:Gm10800
|
UTSW |
2 |
98,497,378 (GRCm39) |
frame shift |
probably null |
|
|
| Posted On |
2013-06-28 |
Incidental Mutation