Mutagenetix > Incidental Mutation

Incidental Mutation 'R9118:Vmn1r152'

692640

Institutional Source

Beutler Lab

Gene Symbol

Vmn1r152

Ensembl Gene

ENSMUSG00000095383

Gene Name

vomeronasal 1 receptor 152

Synonyms

Gm8673

MMRRC Submission

068921-MU

Accession Numbers

Essential gene?

Not available question?

Stock #

R9118 (G1)

Quality Score

117.008

Status

Not validated

Chromosome

Chromosomal Location

22222392-22223315 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 22222992 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Phenylalanine at position 201 (I201F)

Ref Sequence

ENSEMBL: ENSMUSP00000128566 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000168326]

AlphaFold

E9Q9N3

Predicted Effect

SMART Domains

Protein: ENSMUSP00000128566
Gene: ENSMUSG00000095383
AA Change: I201F

Domain	Start	End	E-Value	Type
Pfam:TAS2R	8	299	2.2e-16	PFAM
Pfam:7tm_1	39	291	1.8e-8	PFAM
Pfam:V1R	41	297	9.3e-17	PFAM

Coding Region Coverage

1x: 100.0%
3x: 99.9%
10x: 99.7%
20x: 99.0%

Validation Efficiency

97% (31/32)

Allele List at MGI

Other mutations in this stock

Total: 33 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Acaa1b	A	T	9: 118,985,957 (GRCm39)	S36T	probably benign	Het
Aifm2	C	T	10: 61,561,681 (GRCm39)	T9I	probably benign	Het
Ano5	T	A	7: 51,220,122 (GRCm39)	F421I	probably damaging	Het
Cacna1a	G	A	8: 85,262,715 (GRCm39)	V372M	probably damaging	Het
Col6a5	A	T	9: 105,755,853 (GRCm39)		probably benign	Het
Colgalt2	A	G	1: 152,378,906 (GRCm39)		probably benign	Het
Crybg1	T	C	10: 43,879,925 (GRCm39)	D421G	possibly damaging	Het
Dgat1	A	T	15: 76,386,718 (GRCm39)	W440R	probably damaging	Het
Dnah5	TGTCCGACTACAACATCGAGACGGCCAAGCGCGTC	TGTC	15: 28,401,994 (GRCm39)		probably null	Het
Dnai7	A	G	6: 145,120,900 (GRCm39)	Y691H	probably damaging	Het
Dnai7	A	G	6: 145,120,971 (GRCm39)	L667P	probably damaging	Het
Eif4h	C	A	5: 134,656,481 (GRCm39)	V70L	probably benign	Het
Gabrd	C	A	4: 155,470,475 (GRCm39)	V326L	possibly damaging	Het
Krt1c	C	T	15: 101,722,976 (GRCm39)	E341K	probably damaging	Het
Lrp4	C	T	2: 91,308,927 (GRCm39)	A538V	possibly damaging	Het
Mfap3l	G	A	8: 61,109,716 (GRCm39)	V31M	probably damaging	Het
Mroh2b	T	C	15: 4,991,573 (GRCm39)	I1557T	possibly damaging	Het
Or2y16	A	T	11: 49,335,409 (GRCm39)	I244F	probably benign	Het
Or5an11	T	C	19: 12,246,263 (GRCm39)	V223A	probably benign	Het
Pcyt2	G	A	11: 120,503,899 (GRCm39)	P183L		Het
Rapsn	A	G	2: 90,875,378 (GRCm39)	H387R	probably damaging	Het
Scaf11	G	A	15: 96,319,886 (GRCm39)	A259V	probably benign	Het
Septin9	A	G	11: 117,157,398 (GRCm39)	D11G	probably benign	Het
Sfi1	ACA	ACATCTTCCCAAAGCCAGTCA	11: 3,103,382 (GRCm39)		probably benign	Het
Slc7a2	T	A	8: 41,351,994 (GRCm39)	I19N	possibly damaging	Het
Synpr	T	C	14: 13,608,673 (GRCm38)	V171A	probably damaging	Het
Tmed7	T	C	18: 46,726,338 (GRCm39)	N139S	probably benign	Het
Tnks1bp1	G	T	2: 84,893,720 (GRCm39)	G1216W	probably damaging	Het
Ush2a	T	A	1: 188,386,839 (GRCm39)	V2338E	probably damaging	Het
Vmn2r106	C	A	17: 20,505,667 (GRCm39)	W9L	probably benign	Het
Vmn2r9	A	G	5: 108,990,937 (GRCm39)	V808A	probably damaging	Het
Zfp646	A	G	7: 127,480,810 (GRCm39)	T996A		Het
Zng1	T	C	19: 24,920,048 (GRCm39)	R190G	probably damaging	Het

Other mutations in Vmn1r152

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R4209:Vmn1r152	UTSW	7	22,223,004 (GRCm39)	missense	possibly damaging	0.93
R4210:Vmn1r152	UTSW	7	22,223,004 (GRCm39)	missense	possibly damaging	0.93
R9274:Vmn1r152	UTSW	7	22,223,056 (GRCm39)	missense	probably benign	0.33

Predicted Primers

PCR Primer
(F):5'- AGCAAGTGTCCCAAATTTGTGG -3'
(R):5'- CTGACAAGCCTTATGAAGAGACG -3'

Sequencing Primer
(F):5'- AATTATTCCTGCTACAGTTGTTGG -3'
(R):5'- CAAGCCTTATGAAGAGACGAGAATG -3'

Posted On

2021-12-30