Incidental Mutation 'R1175:Ubap2l'
| ID |
99906 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ubap2l
|
| Ensembl Gene |
ENSMUSG00000042520 |
| Gene Name |
ubiquitin-associated protein 2-like |
| Synonyms |
4932431F02Rik, A430103N23Rik, NICE-4, 3110083O19Rik |
| MMRRC Submission |
039248-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1175 (G1)
|
| Quality Score |
150 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
89907447-89959935 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 89930807 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 413
(S413T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000143254
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029553]
[ENSMUST00000064639]
[ENSMUST00000090908]
[ENSMUST00000195995]
[ENSMUST00000196843]
[ENSMUST00000198322]
[ENSMUST00000199834]
|
| AlphaFold |
Q80X50 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000029553
AA Change: S402T
PolyPhen 2
Score 0.076 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000029553
Gene: ENSMUSG00000042520
AA Change: S402T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
UBA
|
50 |
88 |
1.31e-9 |
SMART |
|
low complexity region
|
124 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
162 |
190 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
226 |
N/A |
INTRINSIC |
|
low complexity region
|
389 |
398 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
409 |
N/A |
INTRINSIC |
|
low complexity region
|
459 |
484 |
N/A |
INTRINSIC |
|
Pfam:DUF3697
|
514 |
546 |
4e-22 |
PFAM |
|
low complexity region
|
554 |
589 |
N/A |
INTRINSIC |
|
low complexity region
|
665 |
675 |
N/A |
INTRINSIC |
|
low complexity region
|
714 |
745 |
N/A |
INTRINSIC |
|
low complexity region
|
748 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
808 |
822 |
N/A |
INTRINSIC |
|
low complexity region
|
893 |
916 |
N/A |
INTRINSIC |
|
low complexity region
|
1038 |
1051 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000064639
AA Change: S407T
PolyPhen 2
Score 0.042 (Sensitivity: 0.94; Specificity: 0.83)
|
| SMART Domains |
Protein: ENSMUSP00000066138
Gene: ENSMUSG00000042520
AA Change: S407T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
UBA
|
50 |
88 |
1.31e-9 |
SMART |
|
low complexity region
|
124 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
162 |
190 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
226 |
N/A |
INTRINSIC |
|
low complexity region
|
394 |
403 |
N/A |
INTRINSIC |
|
low complexity region
|
405 |
414 |
N/A |
INTRINSIC |
|
low complexity region
|
464 |
489 |
N/A |
INTRINSIC |
|
Pfam:DUF3697
|
520 |
551 |
4.1e-18 |
PFAM |
|
low complexity region
|
559 |
594 |
N/A |
INTRINSIC |
|
low complexity region
|
670 |
680 |
N/A |
INTRINSIC |
|
low complexity region
|
719 |
750 |
N/A |
INTRINSIC |
|
low complexity region
|
753 |
809 |
N/A |
INTRINSIC |
|
low complexity region
|
813 |
827 |
N/A |
INTRINSIC |
|
low complexity region
|
898 |
921 |
N/A |
INTRINSIC |
|
low complexity region
|
1043 |
1056 |
N/A |
INTRINSIC |
|
low complexity region
|
1077 |
1092 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000090908
AA Change: S382T
PolyPhen 2
Score 0.177 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000088424
Gene: ENSMUSG00000042520
AA Change: S382T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
UBA
|
50 |
88 |
1.31e-9 |
SMART |
|
low complexity region
|
124 |
148 |
N/A |
INTRINSIC |
|
low complexity region
|
173 |
201 |
N/A |
INTRINSIC |
|
low complexity region
|
224 |
237 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
409 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
420 |
N/A |
INTRINSIC |
|
low complexity region
|
470 |
495 |
N/A |
INTRINSIC |
|
Pfam:DUF3697
|
525 |
557 |
3.6e-22 |
PFAM |
|
low complexity region
|
565 |
600 |
N/A |
INTRINSIC |
|
low complexity region
|
676 |
686 |
N/A |
INTRINSIC |
|
low complexity region
|
725 |
756 |
N/A |
INTRINSIC |
|
low complexity region
|
759 |
815 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
904 |
927 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195995
AA Change: S413T
PolyPhen 2
Score 0.242 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000143638
Gene: ENSMUSG00000042520
AA Change: S413T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
UBA
|
50 |
88 |
1.31e-9 |
SMART |
|
low complexity region
|
124 |
148 |
N/A |
INTRINSIC |
|
low complexity region
|
173 |
201 |
N/A |
INTRINSIC |
|
low complexity region
|
224 |
237 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
409 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
420 |
N/A |
INTRINSIC |
|
low complexity region
|
470 |
495 |
N/A |
INTRINSIC |
|
Pfam:DUF3697
|
526 |
557 |
3.7e-18 |
PFAM |
|
low complexity region
|
565 |
600 |
N/A |
INTRINSIC |
|
low complexity region
|
676 |
686 |
N/A |
INTRINSIC |
|
low complexity region
|
725 |
756 |
N/A |
INTRINSIC |
|
low complexity region
|
759 |
815 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
904 |
927 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000196568
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000196843
AA Change: S402T
PolyPhen 2
Score 0.076 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000143459
Gene: ENSMUSG00000042520
AA Change: S402T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
UBA
|
50 |
88 |
1.31e-9 |
SMART |
|
low complexity region
|
124 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
162 |
190 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
226 |
N/A |
INTRINSIC |
|
low complexity region
|
389 |
398 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
409 |
N/A |
INTRINSIC |
|
low complexity region
|
459 |
484 |
N/A |
INTRINSIC |
|
Pfam:DUF3697
|
514 |
546 |
4e-22 |
PFAM |
|
low complexity region
|
554 |
589 |
N/A |
INTRINSIC |
|
low complexity region
|
665 |
675 |
N/A |
INTRINSIC |
|
low complexity region
|
714 |
745 |
N/A |
INTRINSIC |
|
low complexity region
|
748 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
808 |
822 |
N/A |
INTRINSIC |
|
low complexity region
|
893 |
916 |
N/A |
INTRINSIC |
|
low complexity region
|
1038 |
1051 |
N/A |
INTRINSIC |
|
low complexity region
|
1072 |
1087 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000196952
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000198322
AA Change: S382T
PolyPhen 2
Score 0.033 (Sensitivity: 0.95; Specificity: 0.82)
|
| SMART Domains |
Protein: ENSMUSP00000142524
Gene: ENSMUSG00000042520
AA Change: S382T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
UBA
|
50 |
88 |
1.31e-9 |
SMART |
|
low complexity region
|
124 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
162 |
190 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
226 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
378 |
N/A |
INTRINSIC |
|
low complexity region
|
380 |
389 |
N/A |
INTRINSIC |
|
low complexity region
|
439 |
464 |
N/A |
INTRINSIC |
|
Pfam:DUF3697
|
494 |
526 |
4.1e-22 |
PFAM |
|
low complexity region
|
534 |
569 |
N/A |
INTRINSIC |
|
low complexity region
|
645 |
655 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
725 |
N/A |
INTRINSIC |
|
low complexity region
|
728 |
784 |
N/A |
INTRINSIC |
|
low complexity region
|
788 |
802 |
N/A |
INTRINSIC |
|
low complexity region
|
873 |
896 |
N/A |
INTRINSIC |
|
low complexity region
|
1017 |
1030 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000199834
AA Change: S413T
PolyPhen 2
Score 0.242 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000143254
Gene: ENSMUSG00000042520
AA Change: S413T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
UBA
|
50 |
88 |
1.31e-9 |
SMART |
|
low complexity region
|
124 |
148 |
N/A |
INTRINSIC |
|
low complexity region
|
173 |
201 |
N/A |
INTRINSIC |
|
low complexity region
|
224 |
237 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
409 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
420 |
N/A |
INTRINSIC |
|
low complexity region
|
470 |
495 |
N/A |
INTRINSIC |
|
Pfam:DUF3697
|
525 |
557 |
3.6e-22 |
PFAM |
|
low complexity region
|
565 |
600 |
N/A |
INTRINSIC |
|
low complexity region
|
676 |
686 |
N/A |
INTRINSIC |
|
low complexity region
|
725 |
756 |
N/A |
INTRINSIC |
|
low complexity region
|
759 |
815 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
904 |
927 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200320
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000199612
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000199301
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000197177
|
| Meta Mutation Damage Score |
0.0621 |
| Coding Region Coverage |
- 1x: 98.9%
- 3x: 97.8%
- 10x: 94.7%
- 20x: 88.0%
|
| Validation Efficiency |
100% (74/74) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a transgenic gene disruption exhibit decreased female body size and reduced female fertility. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 71 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610318N02Rik |
T |
A |
16: 16,935,446 (GRCm39) |
H214L |
probably benign |
Het |
| Abca17 |
T |
C |
17: 24,508,325 (GRCm39) |
E1070G |
possibly damaging |
Het |
| Accsl |
A |
T |
2: 93,696,589 (GRCm39) |
|
probably benign |
Het |
| Akp3 |
G |
A |
1: 87,055,593 (GRCm39) |
G547R |
unknown |
Het |
| Anapc1 |
C |
A |
2: 128,522,108 (GRCm39) |
C150F |
probably damaging |
Het |
| Aoc1l3 |
C |
A |
6: 48,967,173 (GRCm39) |
P707H |
probably damaging |
Het |
| Arhgef18 |
T |
A |
8: 3,439,023 (GRCm39) |
|
probably benign |
Het |
| Borcs5 |
T |
A |
6: 134,687,096 (GRCm39) |
N150K |
probably damaging |
Het |
| C9orf72 |
C |
A |
4: 35,218,630 (GRCm39) |
E76D |
probably damaging |
Het |
| Cdh20 |
G |
A |
1: 109,988,862 (GRCm39) |
V255I |
probably benign |
Het |
| Cntnap5c |
C |
A |
17: 58,671,241 (GRCm39) |
T1143K |
possibly damaging |
Het |
| Col7a1 |
A |
C |
9: 108,784,402 (GRCm39) |
T137P |
unknown |
Het |
| Defb8 |
C |
T |
8: 19,495,910 (GRCm39) |
G50E |
probably damaging |
Het |
| Dimt1 |
T |
A |
13: 107,086,193 (GRCm39) |
|
probably benign |
Het |
| Dnajb11 |
T |
A |
16: 22,689,423 (GRCm39) |
D281E |
probably damaging |
Het |
| Eci2 |
G |
T |
13: 35,177,087 (GRCm39) |
N24K |
probably damaging |
Het |
| Fbn1 |
A |
T |
2: 125,236,607 (GRCm39) |
C358S |
probably benign |
Het |
| Fbxl13 |
A |
T |
5: 21,825,602 (GRCm39) |
|
probably benign |
Het |
| Fbxw11 |
T |
C |
11: 32,661,922 (GRCm39) |
C121R |
probably damaging |
Het |
| Fsd2 |
T |
C |
7: 81,209,518 (GRCm39) |
D108G |
probably benign |
Het |
| Gab1 |
C |
A |
8: 81,511,471 (GRCm39) |
R458L |
probably damaging |
Het |
| Ghrhr |
T |
A |
6: 55,365,254 (GRCm39) |
L416* |
probably null |
Het |
| Glipr1l2 |
C |
A |
10: 111,919,371 (GRCm39) |
L31I |
possibly damaging |
Het |
| Gm1818 |
A |
G |
12: 48,602,982 (GRCm39) |
|
noncoding transcript |
Het |
| Gm19965 |
T |
A |
1: 116,748,550 (GRCm39) |
|
probably benign |
Het |
| Gpr149 |
A |
G |
3: 62,511,888 (GRCm39) |
L37P |
probably damaging |
Het |
| Hoxa9 |
A |
G |
6: 52,202,693 (GRCm39) |
I131T |
probably damaging |
Het |
| Itpkc |
T |
C |
7: 26,927,195 (GRCm39) |
I240V |
probably benign |
Het |
| Jakmip3 |
A |
G |
7: 138,629,515 (GRCm39) |
D552G |
probably damaging |
Het |
| Kank4 |
T |
C |
4: 98,653,806 (GRCm39) |
Y874C |
probably damaging |
Het |
| Kdm3a |
T |
C |
6: 71,577,011 (GRCm39) |
E768G |
possibly damaging |
Het |
| Klf6 |
A |
G |
13: 5,911,711 (GRCm39) |
D25G |
probably benign |
Het |
| Lamc1 |
T |
C |
1: 153,122,977 (GRCm39) |
|
probably benign |
Het |
| Laptm4a |
T |
C |
12: 8,986,716 (GRCm39) |
V258A |
probably damaging |
Het |
| Map3k19 |
A |
G |
1: 127,751,617 (GRCm39) |
V578A |
probably benign |
Het |
| Mast1 |
T |
C |
8: 85,651,956 (GRCm39) |
E342G |
probably benign |
Het |
| Mgat5b |
T |
C |
11: 116,868,622 (GRCm39) |
L515P |
probably damaging |
Het |
| Mink1 |
A |
G |
11: 70,502,166 (GRCm39) |
D985G |
probably benign |
Het |
| Mphosph9 |
A |
G |
5: 124,453,739 (GRCm39) |
V191A |
possibly damaging |
Het |
| Muc6 |
C |
T |
7: 141,234,368 (GRCm39) |
G708S |
probably damaging |
Het |
| Pcnt |
A |
T |
10: 76,228,878 (GRCm39) |
|
probably null |
Het |
| Psmd8 |
A |
T |
7: 28,875,598 (GRCm39) |
Y174N |
probably damaging |
Het |
| Ptgdr2 |
C |
A |
19: 10,918,292 (GRCm39) |
R270S |
possibly damaging |
Het |
| Rasal2 |
A |
G |
1: 156,975,218 (GRCm39) |
M1172T |
probably damaging |
Het |
| Rif1 |
A |
G |
2: 51,997,640 (GRCm39) |
|
probably benign |
Het |
| Rnf123 |
C |
T |
9: 107,954,572 (GRCm39) |
R48H |
probably benign |
Het |
| Rsrc1 |
T |
C |
3: 67,263,551 (GRCm39) |
|
probably benign |
Het |
| Rxfp2 |
T |
C |
5: 149,975,021 (GRCm39) |
V210A |
probably benign |
Het |
| Serpinb9d |
C |
T |
13: 33,384,608 (GRCm39) |
P195L |
probably benign |
Het |
| Sis |
A |
G |
3: 72,865,437 (GRCm39) |
|
probably benign |
Het |
| Skint4 |
T |
C |
4: 111,981,793 (GRCm39) |
M246T |
probably benign |
Het |
| Snrnp200 |
C |
A |
2: 127,070,997 (GRCm39) |
R1093S |
probably damaging |
Het |
| Sp100 |
A |
G |
1: 85,629,141 (GRCm39) |
N471D |
possibly damaging |
Het |
| Spmip4 |
T |
A |
6: 50,566,121 (GRCm39) |
K118M |
probably damaging |
Het |
| Ssxb8 |
T |
G |
X: 8,556,062 (GRCm39) |
H88P |
probably damaging |
Het |
| Sufu |
T |
C |
19: 46,389,703 (GRCm39) |
|
probably null |
Het |
| Synpo2l |
G |
A |
14: 20,718,235 (GRCm39) |
T10I |
possibly damaging |
Het |
| Tdo2 |
A |
T |
3: 81,881,683 (GRCm39) |
S40R |
probably damaging |
Het |
| Tent4b |
T |
A |
8: 88,978,635 (GRCm39) |
F445L |
probably damaging |
Het |
| Terb1 |
G |
A |
8: 105,210,938 (GRCm39) |
T363I |
probably benign |
Het |
| Timd4 |
C |
T |
11: 46,708,498 (GRCm39) |
P175S |
probably damaging |
Het |
| Tlr3 |
C |
A |
8: 45,850,171 (GRCm39) |
V833L |
probably damaging |
Het |
| Tpst2 |
T |
A |
5: 112,455,911 (GRCm39) |
M150K |
probably damaging |
Het |
| Trim67 |
T |
A |
8: 125,543,774 (GRCm39) |
V378E |
probably damaging |
Het |
| Tyrp1 |
C |
T |
4: 80,763,105 (GRCm39) |
Q331* |
probably null |
Het |
| Uimc1 |
G |
A |
13: 55,176,415 (GRCm39) |
T701I |
possibly damaging |
Het |
| Vangl2 |
G |
T |
1: 171,832,353 (GRCm39) |
T501N |
probably damaging |
Het |
| Vmn1r60 |
A |
G |
7: 5,547,621 (GRCm39) |
S160P |
probably benign |
Het |
| Vmn2r66 |
G |
T |
7: 84,654,799 (GRCm39) |
D503E |
probably benign |
Het |
| Vmn2r72 |
T |
A |
7: 85,401,152 (GRCm39) |
E89V |
probably damaging |
Het |
| Zfp457 |
G |
A |
13: 67,441,748 (GRCm39) |
P180S |
probably damaging |
Het |
|
| Other mutations in Ubap2l |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01011:Ubap2l
|
APN |
3 |
89,916,563 (GRCm39) |
nonsense |
probably null |
|
|
IGL02606:Ubap2l
|
APN |
3 |
89,945,735 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02809:Ubap2l
|
APN |
3 |
89,928,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Panhandle
|
UTSW |
3 |
89,938,683 (GRCm39) |
splice site |
probably benign |
|
|
plainview
|
UTSW |
3 |
89,946,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0052:Ubap2l
|
UTSW |
3 |
89,946,235 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0052:Ubap2l
|
UTSW |
3 |
89,946,235 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0128:Ubap2l
|
UTSW |
3 |
89,928,680 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0130:Ubap2l
|
UTSW |
3 |
89,928,680 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0502:Ubap2l
|
UTSW |
3 |
89,916,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0619:Ubap2l
|
UTSW |
3 |
89,924,527 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0726:Ubap2l
|
UTSW |
3 |
89,928,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1023:Ubap2l
|
UTSW |
3 |
89,955,180 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R1172:Ubap2l
|
UTSW |
3 |
89,930,807 (GRCm39) |
missense |
probably benign |
0.24 |
|
R1174:Ubap2l
|
UTSW |
3 |
89,930,807 (GRCm39) |
missense |
probably benign |
0.24 |
|
R1191:Ubap2l
|
UTSW |
3 |
89,930,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1432:Ubap2l
|
UTSW |
3 |
89,926,635 (GRCm39) |
missense |
probably benign |
0.11 |
|
R1582:Ubap2l
|
UTSW |
3 |
89,941,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1771:Ubap2l
|
UTSW |
3 |
89,926,538 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2058:Ubap2l
|
UTSW |
3 |
89,938,683 (GRCm39) |
splice site |
probably benign |
|
|
R2059:Ubap2l
|
UTSW |
3 |
89,938,683 (GRCm39) |
splice site |
probably benign |
|
|
R2081:Ubap2l
|
UTSW |
3 |
89,946,271 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2408:Ubap2l
|
UTSW |
3 |
89,916,439 (GRCm39) |
missense |
probably null |
0.99 |
|
R3404:Ubap2l
|
UTSW |
3 |
89,946,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3551:Ubap2l
|
UTSW |
3 |
89,922,758 (GRCm39) |
missense |
unknown |
|
|
R4132:Ubap2l
|
UTSW |
3 |
89,916,491 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4782:Ubap2l
|
UTSW |
3 |
89,928,210 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4798:Ubap2l
|
UTSW |
3 |
89,928,210 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5173:Ubap2l
|
UTSW |
3 |
89,928,337 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5274:Ubap2l
|
UTSW |
3 |
89,920,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5387:Ubap2l
|
UTSW |
3 |
89,913,903 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6548:Ubap2l
|
UTSW |
3 |
89,930,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6912:Ubap2l
|
UTSW |
3 |
89,946,155 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6995:Ubap2l
|
UTSW |
3 |
89,916,548 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7039:Ubap2l
|
UTSW |
3 |
89,909,662 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7323:Ubap2l
|
UTSW |
3 |
89,922,713 (GRCm39) |
missense |
unknown |
|
|
R7512:Ubap2l
|
UTSW |
3 |
89,917,803 (GRCm39) |
missense |
unknown |
|
|
R7815:Ubap2l
|
UTSW |
3 |
89,951,071 (GRCm39) |
nonsense |
probably null |
|
|
R7975:Ubap2l
|
UTSW |
3 |
89,946,076 (GRCm39) |
splice site |
probably null |
|
|
R8200:Ubap2l
|
UTSW |
3 |
89,930,933 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8291:Ubap2l
|
UTSW |
3 |
89,915,538 (GRCm39) |
makesense |
probably null |
|
|
R8424:Ubap2l
|
UTSW |
3 |
89,928,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8441:Ubap2l
|
UTSW |
3 |
89,920,007 (GRCm39) |
missense |
unknown |
|
|
R9098:Ubap2l
|
UTSW |
3 |
89,909,756 (GRCm39) |
missense |
unknown |
|
|
R9373:Ubap2l
|
UTSW |
3 |
89,915,587 (GRCm39) |
missense |
unknown |
|
|
R9421:Ubap2l
|
UTSW |
3 |
89,955,108 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9488:Ubap2l
|
UTSW |
3 |
89,928,656 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1176:Ubap2l
|
UTSW |
3 |
89,926,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Ubap2l
|
UTSW |
3 |
89,909,124 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1186:Ubap2l
|
UTSW |
3 |
89,916,543 (GRCm39) |
missense |
unknown |
|
|
Z1191:Ubap2l
|
UTSW |
3 |
89,916,543 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
|
| Posted On |
2014-01-15 |
Incidental Mutation