Incidental Mutation 'R5274:Ubap2l'
| ID |
403803 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ubap2l
|
| Ensembl Gene |
ENSMUSG00000042520 |
| Gene Name |
ubiquitin-associated protein 2-like |
| Synonyms |
4932431F02Rik, A430103N23Rik, NICE-4, 3110083O19Rik |
| MMRRC Submission |
042837-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R5274 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
89907447-89959935 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 89920037 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Histidine
at position 818
(Y818H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000088424
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029553]
[ENSMUST00000064639]
[ENSMUST00000090908]
[ENSMUST00000195995]
[ENSMUST00000199834]
[ENSMUST00000196843]
[ENSMUST00000198322]
|
| AlphaFold |
Q80X50 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000029553
AA Change: Y838H
|
| SMART Domains |
Protein: ENSMUSP00000029553
Gene: ENSMUSG00000042520
AA Change: Y838H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
UBA
|
50 |
88 |
1.31e-9 |
SMART |
|
low complexity region
|
124 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
162 |
190 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
226 |
N/A |
INTRINSIC |
|
low complexity region
|
389 |
398 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
409 |
N/A |
INTRINSIC |
|
low complexity region
|
459 |
484 |
N/A |
INTRINSIC |
|
Pfam:DUF3697
|
514 |
546 |
4e-22 |
PFAM |
|
low complexity region
|
554 |
589 |
N/A |
INTRINSIC |
|
low complexity region
|
665 |
675 |
N/A |
INTRINSIC |
|
low complexity region
|
714 |
745 |
N/A |
INTRINSIC |
|
low complexity region
|
748 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
808 |
822 |
N/A |
INTRINSIC |
|
low complexity region
|
893 |
916 |
N/A |
INTRINSIC |
|
low complexity region
|
1038 |
1051 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000064639
AA Change: Y843H
|
| SMART Domains |
Protein: ENSMUSP00000066138
Gene: ENSMUSG00000042520
AA Change: Y843H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
UBA
|
50 |
88 |
1.31e-9 |
SMART |
|
low complexity region
|
124 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
162 |
190 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
226 |
N/A |
INTRINSIC |
|
low complexity region
|
394 |
403 |
N/A |
INTRINSIC |
|
low complexity region
|
405 |
414 |
N/A |
INTRINSIC |
|
low complexity region
|
464 |
489 |
N/A |
INTRINSIC |
|
Pfam:DUF3697
|
520 |
551 |
4.1e-18 |
PFAM |
|
low complexity region
|
559 |
594 |
N/A |
INTRINSIC |
|
low complexity region
|
670 |
680 |
N/A |
INTRINSIC |
|
low complexity region
|
719 |
750 |
N/A |
INTRINSIC |
|
low complexity region
|
753 |
809 |
N/A |
INTRINSIC |
|
low complexity region
|
813 |
827 |
N/A |
INTRINSIC |
|
low complexity region
|
898 |
921 |
N/A |
INTRINSIC |
|
low complexity region
|
1043 |
1056 |
N/A |
INTRINSIC |
|
low complexity region
|
1077 |
1092 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000090908
AA Change: Y818H
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000088424
Gene: ENSMUSG00000042520
AA Change: Y818H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
UBA
|
50 |
88 |
1.31e-9 |
SMART |
|
low complexity region
|
124 |
148 |
N/A |
INTRINSIC |
|
low complexity region
|
173 |
201 |
N/A |
INTRINSIC |
|
low complexity region
|
224 |
237 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
409 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
420 |
N/A |
INTRINSIC |
|
low complexity region
|
470 |
495 |
N/A |
INTRINSIC |
|
Pfam:DUF3697
|
525 |
557 |
3.6e-22 |
PFAM |
|
low complexity region
|
565 |
600 |
N/A |
INTRINSIC |
|
low complexity region
|
676 |
686 |
N/A |
INTRINSIC |
|
low complexity region
|
725 |
756 |
N/A |
INTRINSIC |
|
low complexity region
|
759 |
815 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
904 |
927 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000104381
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000183442
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000195995
AA Change: Y849H
|
| SMART Domains |
Protein: ENSMUSP00000143638
Gene: ENSMUSG00000042520
AA Change: Y849H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
UBA
|
50 |
88 |
1.31e-9 |
SMART |
|
low complexity region
|
124 |
148 |
N/A |
INTRINSIC |
|
low complexity region
|
173 |
201 |
N/A |
INTRINSIC |
|
low complexity region
|
224 |
237 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
409 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
420 |
N/A |
INTRINSIC |
|
low complexity region
|
470 |
495 |
N/A |
INTRINSIC |
|
Pfam:DUF3697
|
526 |
557 |
3.7e-18 |
PFAM |
|
low complexity region
|
565 |
600 |
N/A |
INTRINSIC |
|
low complexity region
|
676 |
686 |
N/A |
INTRINSIC |
|
low complexity region
|
725 |
756 |
N/A |
INTRINSIC |
|
low complexity region
|
759 |
815 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
904 |
927 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000196568
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000199834
AA Change: Y849H
|
| SMART Domains |
Protein: ENSMUSP00000143254
Gene: ENSMUSG00000042520
AA Change: Y849H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
UBA
|
50 |
88 |
1.31e-9 |
SMART |
|
low complexity region
|
124 |
148 |
N/A |
INTRINSIC |
|
low complexity region
|
173 |
201 |
N/A |
INTRINSIC |
|
low complexity region
|
224 |
237 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
409 |
N/A |
INTRINSIC |
|
low complexity region
|
411 |
420 |
N/A |
INTRINSIC |
|
low complexity region
|
470 |
495 |
N/A |
INTRINSIC |
|
Pfam:DUF3697
|
525 |
557 |
3.6e-22 |
PFAM |
|
low complexity region
|
565 |
600 |
N/A |
INTRINSIC |
|
low complexity region
|
676 |
686 |
N/A |
INTRINSIC |
|
low complexity region
|
725 |
756 |
N/A |
INTRINSIC |
|
low complexity region
|
759 |
815 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
904 |
927 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000196843
AA Change: Y838H
|
| SMART Domains |
Protein: ENSMUSP00000143459
Gene: ENSMUSG00000042520
AA Change: Y838H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
UBA
|
50 |
88 |
1.31e-9 |
SMART |
|
low complexity region
|
124 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
162 |
190 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
226 |
N/A |
INTRINSIC |
|
low complexity region
|
389 |
398 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
409 |
N/A |
INTRINSIC |
|
low complexity region
|
459 |
484 |
N/A |
INTRINSIC |
|
Pfam:DUF3697
|
514 |
546 |
4e-22 |
PFAM |
|
low complexity region
|
554 |
589 |
N/A |
INTRINSIC |
|
low complexity region
|
665 |
675 |
N/A |
INTRINSIC |
|
low complexity region
|
714 |
745 |
N/A |
INTRINSIC |
|
low complexity region
|
748 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
808 |
822 |
N/A |
INTRINSIC |
|
low complexity region
|
893 |
916 |
N/A |
INTRINSIC |
|
low complexity region
|
1038 |
1051 |
N/A |
INTRINSIC |
|
low complexity region
|
1072 |
1087 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000198322
AA Change: Y818H
|
| SMART Domains |
Protein: ENSMUSP00000142524
Gene: ENSMUSG00000042520
AA Change: Y818H
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
16 |
30 |
N/A |
INTRINSIC |
|
UBA
|
50 |
88 |
1.31e-9 |
SMART |
|
low complexity region
|
124 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
162 |
190 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
226 |
N/A |
INTRINSIC |
|
low complexity region
|
369 |
378 |
N/A |
INTRINSIC |
|
low complexity region
|
380 |
389 |
N/A |
INTRINSIC |
|
low complexity region
|
439 |
464 |
N/A |
INTRINSIC |
|
Pfam:DUF3697
|
494 |
526 |
4.1e-22 |
PFAM |
|
low complexity region
|
534 |
569 |
N/A |
INTRINSIC |
|
low complexity region
|
645 |
655 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
725 |
N/A |
INTRINSIC |
|
low complexity region
|
728 |
784 |
N/A |
INTRINSIC |
|
low complexity region
|
788 |
802 |
N/A |
INTRINSIC |
|
low complexity region
|
873 |
896 |
N/A |
INTRINSIC |
|
low complexity region
|
1017 |
1030 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000197177
AA Change: Y339H
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000197633
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000199612
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200195
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000196747
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000200320
|
| Coding Region Coverage |
- 1x: 99.5%
- 3x: 98.9%
- 10x: 98.0%
- 20x: 96.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a transgenic gene disruption exhibit decreased female body size and reduced female fertility. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 60 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4921539E11Rik |
C |
T |
4: 103,092,856 (GRCm39) |
R155H |
probably benign |
Het |
| Ace |
T |
C |
11: 105,858,863 (GRCm39) |
M19T |
probably benign |
Het |
| Agl |
A |
G |
3: 116,566,135 (GRCm39) |
L995P |
probably damaging |
Het |
| AY761185 |
T |
C |
8: 21,433,889 (GRCm39) |
N90S |
unknown |
Het |
| Brca2 |
T |
C |
5: 150,463,154 (GRCm39) |
S973P |
probably benign |
Het |
| Cacna1e |
T |
C |
1: 154,576,250 (GRCm39) |
T66A |
probably damaging |
Het |
| Cbarp |
T |
C |
10: 79,967,649 (GRCm39) |
S531G |
possibly damaging |
Het |
| Cby2 |
A |
G |
14: 75,820,666 (GRCm39) |
V362A |
probably benign |
Het |
| Cd96 |
G |
T |
16: 45,890,066 (GRCm39) |
T319K |
possibly damaging |
Het |
| Ceacam23 |
T |
C |
7: 17,649,642 (GRCm39) |
|
probably null |
Het |
| Chil5 |
A |
C |
3: 105,936,169 (GRCm39) |
F41C |
probably damaging |
Het |
| Col24a1 |
A |
C |
3: 145,190,433 (GRCm39) |
E1239D |
probably benign |
Het |
| Dip2b |
A |
G |
15: 100,109,985 (GRCm39) |
E1490G |
possibly damaging |
Het |
| Dync1li1 |
T |
C |
9: 114,544,273 (GRCm39) |
V315A |
possibly damaging |
Het |
| Dync2h1 |
T |
C |
9: 7,116,540 (GRCm39) |
S99G |
probably benign |
Het |
| Dynlt5 |
A |
T |
4: 102,859,768 (GRCm39) |
T103S |
possibly damaging |
Het |
| E2f8 |
C |
T |
7: 48,516,925 (GRCm39) |
R818H |
probably damaging |
Het |
| Eomes |
T |
C |
9: 118,309,597 (GRCm39) |
V250A |
probably damaging |
Het |
| Esyt3 |
T |
C |
9: 99,200,350 (GRCm39) |
T615A |
probably benign |
Het |
| Fbxo38 |
A |
T |
18: 62,648,140 (GRCm39) |
D799E |
probably damaging |
Het |
| Fdft1 |
A |
G |
14: 63,389,792 (GRCm39) |
F288S |
probably damaging |
Het |
| Gm14325 |
G |
A |
2: 177,474,777 (GRCm39) |
H102Y |
possibly damaging |
Het |
| Gm4871 |
C |
G |
5: 144,967,180 (GRCm39) |
E185Q |
probably damaging |
Het |
| Gm5901 |
C |
A |
7: 105,026,655 (GRCm39) |
P141Q |
probably damaging |
Het |
| Herc1 |
T |
A |
9: 66,306,691 (GRCm39) |
I933N |
probably benign |
Het |
| Ifih1 |
T |
C |
2: 62,442,062 (GRCm39) |
Q385R |
probably benign |
Het |
| Ighmbp2 |
T |
C |
19: 3,315,518 (GRCm39) |
E634G |
probably damaging |
Het |
| Klk6 |
C |
G |
7: 43,478,553 (GRCm39) |
|
probably null |
Het |
| Kmt2d |
A |
G |
15: 98,752,111 (GRCm39) |
|
probably benign |
Het |
| Lig3 |
T |
A |
11: 82,688,118 (GRCm39) |
|
probably null |
Het |
| Lrp1b |
T |
C |
2: 41,234,456 (GRCm39) |
D310G |
probably null |
Het |
| Mroh6 |
A |
G |
15: 75,756,849 (GRCm39) |
V571A |
possibly damaging |
Het |
| Olfm5 |
A |
G |
7: 103,809,190 (GRCm39) |
S132P |
probably damaging |
Het |
| Or52n20 |
T |
C |
7: 104,320,733 (GRCm39) |
S275P |
probably damaging |
Het |
| Or5p64 |
A |
T |
7: 107,854,842 (GRCm39) |
F168I |
probably benign |
Het |
| Pacc1 |
T |
C |
1: 191,080,665 (GRCm39) |
V295A |
probably damaging |
Het |
| Patj |
G |
C |
4: 98,407,218 (GRCm39) |
S4T |
probably damaging |
Het |
| Pcdhga12 |
T |
A |
18: 37,899,475 (GRCm39) |
C102* |
probably null |
Het |
| Pik3ap1 |
T |
C |
19: 41,270,391 (GRCm39) |
D766G |
possibly damaging |
Het |
| Plch2 |
A |
T |
4: 155,083,411 (GRCm39) |
L408Q |
probably damaging |
Het |
| Pnma2 |
G |
T |
14: 67,154,209 (GRCm39) |
R211L |
probably damaging |
Het |
| Prkg2 |
T |
A |
5: 99,117,850 (GRCm39) |
H468L |
probably damaging |
Het |
| Rad1 |
T |
A |
15: 10,488,059 (GRCm39) |
|
probably null |
Het |
| Rims3 |
A |
G |
4: 120,748,571 (GRCm39) |
D264G |
probably damaging |
Het |
| Rnf123 |
AT |
ATT |
9: 107,941,202 (GRCm39) |
|
probably null |
Het |
| Rrm2 |
T |
A |
12: 24,760,406 (GRCm39) |
Y75* |
probably null |
Het |
| Sall3 |
T |
C |
18: 81,013,052 (GRCm39) |
N1128S |
probably benign |
Het |
| Slc26a5 |
T |
C |
5: 22,018,899 (GRCm39) |
T610A |
possibly damaging |
Het |
| Snx29 |
G |
T |
16: 11,556,268 (GRCm39) |
E766D |
probably damaging |
Het |
| Sox17 |
A |
G |
1: 4,562,111 (GRCm39) |
V298A |
possibly damaging |
Het |
| Ss18 |
G |
A |
18: 14,774,106 (GRCm39) |
Q228* |
probably null |
Het |
| Tas2r121 |
A |
G |
6: 132,677,811 (GRCm39) |
S54P |
probably damaging |
Het |
| Ttc21b |
T |
C |
2: 66,066,627 (GRCm39) |
E342G |
possibly damaging |
Het |
| Usp15 |
C |
A |
10: 123,004,256 (GRCm39) |
R166I |
probably damaging |
Het |
| Vmn1r34 |
T |
G |
6: 66,614,123 (GRCm39) |
H205P |
probably damaging |
Het |
| Vmn2r22 |
A |
T |
6: 123,627,593 (GRCm39) |
M1K |
probably null |
Het |
| Vps51 |
T |
G |
19: 6,121,063 (GRCm39) |
E283D |
probably benign |
Het |
| Zdhhc1 |
T |
C |
8: 106,210,402 (GRCm39) |
N5S |
probably benign |
Het |
| Zfp758 |
T |
A |
17: 22,594,836 (GRCm39) |
C441S |
probably benign |
Het |
| Zp2 |
T |
C |
7: 119,737,315 (GRCm39) |
E291G |
possibly damaging |
Het |
|
| Other mutations in Ubap2l |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01011:Ubap2l
|
APN |
3 |
89,916,563 (GRCm39) |
nonsense |
probably null |
|
|
IGL02606:Ubap2l
|
APN |
3 |
89,945,735 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02809:Ubap2l
|
APN |
3 |
89,928,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Panhandle
|
UTSW |
3 |
89,938,683 (GRCm39) |
splice site |
probably benign |
|
|
plainview
|
UTSW |
3 |
89,946,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0052:Ubap2l
|
UTSW |
3 |
89,946,235 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0052:Ubap2l
|
UTSW |
3 |
89,946,235 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0128:Ubap2l
|
UTSW |
3 |
89,928,680 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0130:Ubap2l
|
UTSW |
3 |
89,928,680 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0502:Ubap2l
|
UTSW |
3 |
89,916,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0619:Ubap2l
|
UTSW |
3 |
89,924,527 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0726:Ubap2l
|
UTSW |
3 |
89,928,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1023:Ubap2l
|
UTSW |
3 |
89,955,180 (GRCm39) |
utr 5 prime |
probably benign |
|
|
R1172:Ubap2l
|
UTSW |
3 |
89,930,807 (GRCm39) |
missense |
probably benign |
0.24 |
|
R1174:Ubap2l
|
UTSW |
3 |
89,930,807 (GRCm39) |
missense |
probably benign |
0.24 |
|
R1175:Ubap2l
|
UTSW |
3 |
89,930,807 (GRCm39) |
missense |
probably benign |
0.24 |
|
R1191:Ubap2l
|
UTSW |
3 |
89,930,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1432:Ubap2l
|
UTSW |
3 |
89,926,635 (GRCm39) |
missense |
probably benign |
0.11 |
|
R1582:Ubap2l
|
UTSW |
3 |
89,941,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1771:Ubap2l
|
UTSW |
3 |
89,926,538 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2058:Ubap2l
|
UTSW |
3 |
89,938,683 (GRCm39) |
splice site |
probably benign |
|
|
R2059:Ubap2l
|
UTSW |
3 |
89,938,683 (GRCm39) |
splice site |
probably benign |
|
|
R2081:Ubap2l
|
UTSW |
3 |
89,946,271 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2408:Ubap2l
|
UTSW |
3 |
89,916,439 (GRCm39) |
missense |
probably null |
0.99 |
|
R3404:Ubap2l
|
UTSW |
3 |
89,946,157 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3551:Ubap2l
|
UTSW |
3 |
89,922,758 (GRCm39) |
missense |
unknown |
|
|
R4132:Ubap2l
|
UTSW |
3 |
89,916,491 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4782:Ubap2l
|
UTSW |
3 |
89,928,210 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4798:Ubap2l
|
UTSW |
3 |
89,928,210 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5173:Ubap2l
|
UTSW |
3 |
89,928,337 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5387:Ubap2l
|
UTSW |
3 |
89,913,903 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6548:Ubap2l
|
UTSW |
3 |
89,930,867 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6912:Ubap2l
|
UTSW |
3 |
89,946,155 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R6995:Ubap2l
|
UTSW |
3 |
89,916,548 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7039:Ubap2l
|
UTSW |
3 |
89,909,662 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7323:Ubap2l
|
UTSW |
3 |
89,922,713 (GRCm39) |
missense |
unknown |
|
|
R7512:Ubap2l
|
UTSW |
3 |
89,917,803 (GRCm39) |
missense |
unknown |
|
|
R7815:Ubap2l
|
UTSW |
3 |
89,951,071 (GRCm39) |
nonsense |
probably null |
|
|
R7975:Ubap2l
|
UTSW |
3 |
89,946,076 (GRCm39) |
splice site |
probably null |
|
|
R8200:Ubap2l
|
UTSW |
3 |
89,930,933 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8291:Ubap2l
|
UTSW |
3 |
89,915,538 (GRCm39) |
makesense |
probably null |
|
|
R8424:Ubap2l
|
UTSW |
3 |
89,928,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8441:Ubap2l
|
UTSW |
3 |
89,920,007 (GRCm39) |
missense |
unknown |
|
|
R9098:Ubap2l
|
UTSW |
3 |
89,909,756 (GRCm39) |
missense |
unknown |
|
|
R9373:Ubap2l
|
UTSW |
3 |
89,915,587 (GRCm39) |
missense |
unknown |
|
|
R9421:Ubap2l
|
UTSW |
3 |
89,955,108 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9488:Ubap2l
|
UTSW |
3 |
89,928,656 (GRCm39) |
missense |
probably benign |
0.02 |
|
Z1176:Ubap2l
|
UTSW |
3 |
89,926,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Ubap2l
|
UTSW |
3 |
89,909,124 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1186:Ubap2l
|
UTSW |
3 |
89,916,543 (GRCm39) |
missense |
unknown |
|
|
Z1191:Ubap2l
|
UTSW |
3 |
89,916,543 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GAACATCTGAGAATCCTTCCATCAG -3'
(R):5'- CAGGAAAGCTTTAAGACCTTTCATG -3'
Sequencing Primer
(F):5'- TGGGCATGCCATTAATCCCAG -3'
(R):5'- GCTTTGTTCTGACAATGAGG -3'
|
| Posted On |
2016-07-22 |
Incidental Mutation