Incidental Mutation 'R1468:Ralgapb'
| ID |
164655 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ralgapb
|
| Ensembl Gene |
ENSMUSG00000027652 |
| Gene Name |
Ral GTPase activating protein, beta subunit (non-catalytic) |
| Synonyms |
B230339M05Rik |
| MMRRC Submission |
039521-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1468 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
158251768-158341173 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 158304173 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 644
(E644G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000116481
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046274]
[ENSMUST00000109485]
[ENSMUST00000109486]
[ENSMUST00000141497]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000046274
AA Change: E962G
PolyPhen 2
Score 0.949 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000048430
Gene: ENSMUSG00000027652
AA Change: E962G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
775 |
788 |
N/A |
INTRINSIC |
|
low complexity region
|
910 |
920 |
N/A |
INTRINSIC |
|
low complexity region
|
1086 |
1097 |
N/A |
INTRINSIC |
|
low complexity region
|
1309 |
1321 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000109485
AA Change: E978G
PolyPhen 2
Score 0.949 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000105111
Gene: ENSMUSG00000027652
AA Change: E978G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
622 |
637 |
N/A |
INTRINSIC |
|
low complexity region
|
791 |
804 |
N/A |
INTRINSIC |
|
low complexity region
|
926 |
936 |
N/A |
INTRINSIC |
|
low complexity region
|
1102 |
1113 |
N/A |
INTRINSIC |
|
low complexity region
|
1325 |
1337 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000109486
AA Change: E966G
PolyPhen 2
Score 0.949 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000105112
Gene: ENSMUSG00000027652
AA Change: E966G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
166 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
610 |
625 |
N/A |
INTRINSIC |
|
low complexity region
|
779 |
792 |
N/A |
INTRINSIC |
|
low complexity region
|
914 |
924 |
N/A |
INTRINSIC |
|
low complexity region
|
1090 |
1101 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1325 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000141497
AA Change: E644G
PolyPhen 2
Score 0.949 (Sensitivity: 0.79; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000116481
Gene: ENSMUSG00000027652
AA Change: E644G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
288 |
303 |
N/A |
INTRINSIC |
|
low complexity region
|
457 |
470 |
N/A |
INTRINSIC |
|
low complexity region
|
592 |
602 |
N/A |
INTRINSIC |
|
low complexity region
|
768 |
779 |
N/A |
INTRINSIC |
|
low complexity region
|
991 |
1003 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150420
|
| Meta Mutation Damage Score |
0.1457 |
| Coding Region Coverage |
- 1x: 99.7%
- 3x: 98.4%
- 10x: 90.8%
- 20x: 69.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2900092C05Rik |
T |
G |
7: 12,246,507 (GRCm39) |
M1R |
probably null |
Het |
| 5031439G07Rik |
G |
T |
15: 84,837,345 (GRCm39) |
P280T |
probably damaging |
Het |
| Abca2 |
C |
T |
2: 25,331,308 (GRCm39) |
S1267L |
probably damaging |
Het |
| Acsl3 |
A |
T |
1: 78,684,126 (GRCm39) |
R719S |
probably benign |
Het |
| Adam1a |
A |
T |
5: 121,657,839 (GRCm39) |
|
probably null |
Het |
| Aldh6a1 |
T |
C |
12: 84,488,544 (GRCm39) |
E89G |
possibly damaging |
Het |
| Ankrd36 |
A |
G |
11: 5,525,752 (GRCm39) |
Y238C |
probably damaging |
Het |
| Ankrd65 |
G |
A |
4: 155,877,362 (GRCm39) |
R291Q |
probably benign |
Het |
| Ano2 |
C |
T |
6: 125,773,227 (GRCm39) |
R287W |
probably damaging |
Het |
| Ap1ar |
A |
G |
3: 127,606,215 (GRCm39) |
I125T |
probably benign |
Het |
| Arid1b |
A |
G |
17: 5,293,197 (GRCm39) |
D705G |
probably damaging |
Het |
| Asb18 |
T |
A |
1: 89,924,005 (GRCm39) |
N86I |
probably damaging |
Het |
| Bicral |
A |
T |
17: 47,135,519 (GRCm39) |
S564T |
probably benign |
Het |
| Bpifa6 |
A |
G |
2: 153,831,192 (GRCm39) |
M253V |
probably benign |
Het |
| Braf |
T |
C |
6: 39,642,017 (GRCm39) |
D194G |
probably damaging |
Het |
| Brinp3 |
C |
A |
1: 146,777,700 (GRCm39) |
P716T |
probably benign |
Het |
| C7 |
T |
A |
15: 5,041,631 (GRCm39) |
Y425F |
probably damaging |
Het |
| Ccdc102a |
T |
C |
8: 95,632,714 (GRCm39) |
K421R |
probably benign |
Het |
| Cep89 |
G |
A |
7: 35,120,388 (GRCm39) |
|
probably null |
Het |
| Chgb |
A |
T |
2: 132,634,720 (GRCm39) |
M221L |
probably benign |
Het |
| Chst14 |
A |
G |
2: 118,758,145 (GRCm39) |
Y313C |
probably damaging |
Het |
| Ciita |
G |
A |
16: 10,331,152 (GRCm39) |
|
probably null |
Het |
| Clec12b |
A |
T |
6: 129,357,603 (GRCm39) |
I85N |
probably damaging |
Het |
| Clec2e |
G |
T |
6: 129,070,459 (GRCm39) |
Y187* |
probably null |
Het |
| Crbn |
T |
C |
6: 106,767,804 (GRCm39) |
K229E |
probably benign |
Het |
| Ctdspl2 |
A |
T |
2: 121,811,762 (GRCm39) |
Q201L |
probably benign |
Het |
| Cyp2c55 |
T |
A |
19: 38,999,525 (GRCm39) |
V77E |
probably damaging |
Het |
| Cyp2c69 |
A |
C |
19: 39,837,839 (GRCm39) |
D414E |
probably damaging |
Het |
| Dlg1 |
A |
G |
16: 31,661,640 (GRCm39) |
|
probably null |
Het |
| Dnah5 |
C |
A |
15: 28,230,609 (GRCm39) |
S169* |
probably null |
Het |
| Dock4 |
C |
A |
12: 40,805,809 (GRCm39) |
T927K |
probably benign |
Het |
| Esrp2 |
T |
G |
8: 106,860,453 (GRCm39) |
D259A |
probably damaging |
Het |
| Fam169a |
A |
G |
13: 97,255,038 (GRCm39) |
K418R |
probably benign |
Het |
| Fancm |
A |
T |
12: 65,146,067 (GRCm39) |
I597F |
probably damaging |
Het |
| Fat1 |
G |
A |
8: 45,463,582 (GRCm39) |
V1375M |
probably damaging |
Het |
| Fbxw10 |
A |
T |
11: 62,753,464 (GRCm39) |
D486V |
probably damaging |
Het |
| Fermt1 |
C |
T |
2: 132,766,942 (GRCm39) |
E342K |
probably benign |
Het |
| Foxp1 |
T |
A |
6: 98,955,181 (GRCm39) |
H195L |
possibly damaging |
Het |
| Gfra1 |
T |
A |
19: 58,440,407 (GRCm39) |
I138L |
probably benign |
Het |
| Gm12185 |
T |
C |
11: 48,806,501 (GRCm39) |
D230G |
possibly damaging |
Het |
| Gpd2 |
A |
C |
2: 57,245,786 (GRCm39) |
T439P |
probably damaging |
Het |
| Gpm6a |
A |
T |
8: 55,490,385 (GRCm39) |
K20N |
probably damaging |
Het |
| Hc |
A |
T |
2: 34,873,819 (GRCm39) |
Y158* |
probably null |
Het |
| Hectd4 |
A |
T |
5: 121,487,235 (GRCm39) |
D3410V |
possibly damaging |
Het |
| Il17b |
G |
A |
18: 61,823,483 (GRCm39) |
|
probably null |
Het |
| Irx4 |
G |
T |
13: 73,413,695 (GRCm39) |
R55L |
possibly damaging |
Het |
| Lama3 |
T |
C |
18: 12,574,164 (GRCm39) |
V582A |
probably benign |
Het |
| Ldhd |
G |
T |
8: 112,353,925 (GRCm39) |
A425E |
possibly damaging |
Het |
| Lrp1b |
C |
T |
2: 40,817,841 (GRCm39) |
|
probably null |
Het |
| Lrp5 |
T |
C |
19: 3,670,191 (GRCm39) |
T638A |
possibly damaging |
Het |
| Lrrk1 |
A |
C |
7: 65,909,722 (GRCm39) |
F1996C |
probably damaging |
Het |
| Ly6h |
G |
A |
15: 75,437,986 (GRCm39) |
S21L |
probably benign |
Het |
| Mctp1 |
T |
C |
13: 76,973,392 (GRCm39) |
V431A |
probably benign |
Het |
| Metap2 |
C |
T |
10: 93,707,345 (GRCm39) |
|
probably null |
Het |
| Mfsd2b |
T |
A |
12: 4,920,536 (GRCm39) |
K94* |
probably null |
Het |
| Micall2 |
A |
G |
5: 139,705,097 (GRCm39) |
L79P |
probably damaging |
Het |
| Mucl2 |
T |
C |
15: 103,927,673 (GRCm39) |
T95A |
possibly damaging |
Het |
| Myo15a |
A |
T |
11: 60,396,832 (GRCm39) |
T2634S |
probably damaging |
Het |
| Myo5b |
G |
T |
18: 74,873,574 (GRCm39) |
V1467L |
probably damaging |
Het |
| Nfic |
G |
T |
10: 81,256,414 (GRCm39) |
D105E |
probably damaging |
Het |
| Nrdc |
T |
A |
4: 108,873,865 (GRCm39) |
F227Y |
probably benign |
Het |
| Nrp2 |
A |
T |
1: 62,777,458 (GRCm39) |
I88F |
probably damaging |
Het |
| Nup160 |
A |
T |
2: 90,530,887 (GRCm39) |
H515L |
probably benign |
Het |
| Nup205 |
G |
A |
6: 35,202,917 (GRCm39) |
|
probably null |
Het |
| Oas1g |
G |
A |
5: 121,020,069 (GRCm39) |
T179I |
probably benign |
Het |
| Ogfr |
A |
T |
2: 180,236,543 (GRCm39) |
E376V |
probably damaging |
Het |
| Or2l13 |
T |
G |
16: 19,306,378 (GRCm39) |
S263R |
probably benign |
Het |
| Or4a69 |
A |
T |
2: 89,312,855 (GRCm39) |
V208D |
possibly damaging |
Het |
| Or4c107 |
T |
G |
2: 88,789,387 (GRCm39) |
Y192* |
probably null |
Het |
| Or52d1 |
G |
T |
7: 103,755,896 (GRCm39) |
V137F |
possibly damaging |
Het |
| Or5p6 |
C |
T |
7: 107,631,595 (GRCm39) |
|
probably null |
Het |
| Pard3b |
T |
C |
1: 62,384,188 (GRCm39) |
V851A |
probably benign |
Het |
| Pcdhb16 |
A |
T |
18: 37,611,142 (GRCm39) |
Y34F |
probably damaging |
Het |
| Pikfyve |
T |
C |
1: 65,290,825 (GRCm39) |
Y1215H |
probably damaging |
Het |
| Pkhd1 |
A |
T |
1: 20,593,565 (GRCm39) |
V1516E |
probably damaging |
Het |
| Ptprg |
A |
T |
14: 12,190,767 (GRCm38) |
I818F |
probably benign |
Het |
| Rbm45 |
A |
G |
2: 76,202,459 (GRCm39) |
I127M |
probably damaging |
Het |
| Rtp2 |
T |
C |
16: 23,746,220 (GRCm39) |
Y157C |
probably damaging |
Het |
| Sf3b3 |
A |
T |
8: 111,564,006 (GRCm39) |
Y329N |
probably damaging |
Het |
| Sfxn1 |
A |
G |
13: 54,239,646 (GRCm39) |
|
probably null |
Het |
| Shkbp1 |
A |
T |
7: 27,044,751 (GRCm39) |
C447S |
probably damaging |
Het |
| Sipa1l3 |
A |
G |
7: 29,021,685 (GRCm39) |
S689P |
possibly damaging |
Het |
| Slc7a8 |
A |
G |
14: 54,970,656 (GRCm39) |
S332P |
probably damaging |
Het |
| Slit1 |
C |
A |
19: 41,596,823 (GRCm39) |
C1092F |
probably damaging |
Het |
| Stard9 |
A |
G |
2: 120,533,678 (GRCm39) |
I619V |
possibly damaging |
Het |
| Sycp3 |
T |
C |
10: 88,305,454 (GRCm39) |
V185A |
possibly damaging |
Het |
| Taar9 |
A |
T |
10: 23,985,382 (GRCm39) |
N17K |
possibly damaging |
Het |
| Tbkbp1 |
T |
C |
11: 97,039,814 (GRCm39) |
E102G |
probably damaging |
Het |
| Tex44 |
A |
G |
1: 86,354,834 (GRCm39) |
N248D |
probably benign |
Het |
| Tmem63b |
C |
G |
17: 45,989,904 (GRCm39) |
R88P |
possibly damaging |
Het |
| Tnpo1 |
C |
T |
13: 98,986,665 (GRCm39) |
V781I |
probably benign |
Het |
| Tonsl |
C |
T |
15: 76,520,761 (GRCm39) |
|
probably null |
Het |
| Ttc6 |
A |
G |
12: 57,721,463 (GRCm39) |
K984R |
possibly damaging |
Het |
| Usp34 |
A |
G |
11: 23,391,171 (GRCm39) |
E2263G |
probably damaging |
Het |
| Usp8 |
A |
G |
2: 126,596,847 (GRCm39) |
K875E |
probably damaging |
Het |
| Vmn1r223 |
A |
G |
13: 23,434,038 (GRCm39) |
I211V |
possibly damaging |
Het |
| Vmn2r81 |
G |
A |
10: 79,129,496 (GRCm39) |
V796I |
probably damaging |
Het |
| Wdr90 |
A |
T |
17: 26,073,027 (GRCm39) |
V856D |
probably damaging |
Het |
| Wnk2 |
T |
A |
13: 49,235,571 (GRCm39) |
T615S |
probably damaging |
Het |
|
| Other mutations in Ralgapb |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00094:Ralgapb
|
APN |
2 |
158,262,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00534:Ralgapb
|
APN |
2 |
158,272,420 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL01362:Ralgapb
|
APN |
2 |
158,277,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01653:Ralgapb
|
APN |
2 |
158,304,079 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01704:Ralgapb
|
APN |
2 |
158,262,795 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02000:Ralgapb
|
APN |
2 |
158,296,034 (GRCm39) |
splice site |
probably benign |
|
|
IGL02169:Ralgapb
|
APN |
2 |
158,268,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02516:Ralgapb
|
APN |
2 |
158,307,735 (GRCm39) |
splice site |
probably benign |
|
|
IGL02548:Ralgapb
|
APN |
2 |
158,286,585 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02550:Ralgapb
|
APN |
2 |
158,290,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02653:Ralgapb
|
APN |
2 |
158,285,229 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02744:Ralgapb
|
APN |
2 |
158,288,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02804:Ralgapb
|
APN |
2 |
158,268,204 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL02937:Ralgapb
|
APN |
2 |
158,334,936 (GRCm39) |
splice site |
probably null |
|
|
IGL02993:Ralgapb
|
APN |
2 |
158,279,314 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL03154:Ralgapb
|
APN |
2 |
158,274,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03204:Ralgapb
|
APN |
2 |
158,307,832 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL03347:Ralgapb
|
APN |
2 |
158,307,880 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
Chacha
|
UTSW |
2 |
158,334,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Gato
|
UTSW |
2 |
158,286,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Kibble
|
UTSW |
2 |
158,279,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ralston
|
UTSW |
2 |
158,296,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4142001:Ralgapb
|
UTSW |
2 |
158,272,342 (GRCm39) |
missense |
probably benign |
0.34 |
|
R0037:Ralgapb
|
UTSW |
2 |
158,279,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0037:Ralgapb
|
UTSW |
2 |
158,279,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0077:Ralgapb
|
UTSW |
2 |
158,315,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0581:Ralgapb
|
UTSW |
2 |
158,334,881 (GRCm39) |
missense |
probably benign |
|
|
R0629:Ralgapb
|
UTSW |
2 |
158,281,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0839:Ralgapb
|
UTSW |
2 |
158,315,203 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1331:Ralgapb
|
UTSW |
2 |
158,272,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1468:Ralgapb
|
UTSW |
2 |
158,304,173 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1540:Ralgapb
|
UTSW |
2 |
158,307,746 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1572:Ralgapb
|
UTSW |
2 |
158,288,119 (GRCm39) |
splice site |
probably benign |
|
|
R1628:Ralgapb
|
UTSW |
2 |
158,272,383 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1718:Ralgapb
|
UTSW |
2 |
158,285,200 (GRCm39) |
nonsense |
probably null |
|
|
R1777:Ralgapb
|
UTSW |
2 |
158,304,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1822:Ralgapb
|
UTSW |
2 |
158,334,372 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1903:Ralgapb
|
UTSW |
2 |
158,337,483 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1909:Ralgapb
|
UTSW |
2 |
158,286,595 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2157:Ralgapb
|
UTSW |
2 |
158,279,392 (GRCm39) |
missense |
probably benign |
0.15 |
|
R4524:Ralgapb
|
UTSW |
2 |
158,279,226 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4946:Ralgapb
|
UTSW |
2 |
158,282,887 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4975:Ralgapb
|
UTSW |
2 |
158,277,428 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5014:Ralgapb
|
UTSW |
2 |
158,337,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5165:Ralgapb
|
UTSW |
2 |
158,307,832 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R5465:Ralgapb
|
UTSW |
2 |
158,290,325 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5526:Ralgapb
|
UTSW |
2 |
158,274,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5566:Ralgapb
|
UTSW |
2 |
158,336,630 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5949:Ralgapb
|
UTSW |
2 |
158,296,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6140:Ralgapb
|
UTSW |
2 |
158,298,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6175:Ralgapb
|
UTSW |
2 |
158,288,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6192:Ralgapb
|
UTSW |
2 |
158,291,367 (GRCm39) |
splice site |
probably null |
|
|
R6364:Ralgapb
|
UTSW |
2 |
158,304,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6458:Ralgapb
|
UTSW |
2 |
158,286,540 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6746:Ralgapb
|
UTSW |
2 |
158,318,056 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6782:Ralgapb
|
UTSW |
2 |
158,278,486 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6788:Ralgapb
|
UTSW |
2 |
158,278,486 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7017:Ralgapb
|
UTSW |
2 |
158,290,257 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7108:Ralgapb
|
UTSW |
2 |
158,336,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7108:Ralgapb
|
UTSW |
2 |
158,334,380 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7236:Ralgapb
|
UTSW |
2 |
158,282,747 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7454:Ralgapb
|
UTSW |
2 |
158,274,822 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7485:Ralgapb
|
UTSW |
2 |
158,285,275 (GRCm39) |
missense |
probably benign |
0.35 |
|
R7595:Ralgapb
|
UTSW |
2 |
158,268,085 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7615:Ralgapb
|
UTSW |
2 |
158,292,190 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7728:Ralgapb
|
UTSW |
2 |
158,324,423 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7913:Ralgapb
|
UTSW |
2 |
158,307,859 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7953:Ralgapb
|
UTSW |
2 |
158,307,803 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8245:Ralgapb
|
UTSW |
2 |
158,285,256 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8337:Ralgapb
|
UTSW |
2 |
158,292,192 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8363:Ralgapb
|
UTSW |
2 |
158,268,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8429:Ralgapb
|
UTSW |
2 |
158,268,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8673:Ralgapb
|
UTSW |
2 |
158,292,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8955:Ralgapb
|
UTSW |
2 |
158,337,389 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8955:Ralgapb
|
UTSW |
2 |
158,279,264 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8992:Ralgapb
|
UTSW |
2 |
158,296,197 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9013:Ralgapb
|
UTSW |
2 |
158,279,060 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9141:Ralgapb
|
UTSW |
2 |
158,262,811 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9166:Ralgapb
|
UTSW |
2 |
158,274,842 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9242:Ralgapb
|
UTSW |
2 |
158,277,386 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9274:Ralgapb
|
UTSW |
2 |
158,278,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9354:Ralgapb
|
UTSW |
2 |
158,279,313 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9454:Ralgapb
|
UTSW |
2 |
158,315,072 (GRCm39) |
missense |
probably benign |
0.30 |
|
R9489:Ralgapb
|
UTSW |
2 |
158,268,283 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9490:Ralgapb
|
UTSW |
2 |
158,334,350 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9510:Ralgapb
|
UTSW |
2 |
158,285,856 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Ralgapb
|
UTSW |
2 |
158,277,475 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCCACAGGGAGTATATCTGACTCG -3'
(R):5'- AGGGTCCAAGGTTCACATGGACAC -3'
Sequencing Primer
(F):5'- TATTCAGTTAATTCAGAGGGGCAG -3'
(R):5'- GACACCATGATATTTCAGGCATAC -3'
|
| Posted On |
2014-03-28 |
Incidental Mutation