Mutagenetix > Incidental Mutation

Incidental Mutation 'R1710:Vps13c'

190450

Institutional Source

Beutler Lab

Gene Symbol

Vps13c

Ensembl Gene

ENSMUSG00000035284

Gene Name

vacuolar protein sorting 13C

Synonyms

C230055H22Rik

MMRRC Submission

039743-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1710 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

67747678-67902920 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 67818811 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Arginine at position 1077 (S1077R)

Ref Sequence

ENSEMBL: ENSMUSP00000077040 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000077879]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000077879
AA Change: S1077R

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000077040
Gene: ENSMUSG00000035284
AA Change: S1077R

Domain	Start	End	E-Value	Type
Pfam:Chorein_N	3	117	1.3e-39	PFAM
low complexity region	151	165	N/A	INTRINSIC
Pfam:VPS13	182	414	7.9e-70	PFAM
coiled coil region	422	443	N/A	INTRINSIC
low complexity region	479	490	N/A	INTRINSIC
Pfam:VPS13_mid_rpt	611	832	7.8e-71	PFAM
low complexity region	867	885	N/A	INTRINSIC
low complexity region	1020	1036	N/A	INTRINSIC
low complexity region	1112	1123	N/A	INTRINSIC
Pfam:VPS13_mid_rpt	1172	1369	2.1e-14	PFAM
low complexity region	1552	1573	N/A	INTRINSIC
Pfam:VPS13_mid_rpt	1685	1883	2.8e-13	PFAM
Blast:INB	2128	2403	2e-48	BLAST
Pfam:SHR-BD	2759	3013	9.9e-32	PFAM
Pfam:VPS13_C	3317	3495	5.7e-65	PFAM
Pfam:ATG_C	3498	3588	7.9e-12	PFAM

Meta Mutation Damage Score

0.0580

Coding Region Coverage

1x: 99.1%
3x: 98.4%
10x: 96.6%
20x: 93.5%

Validation Efficiency

98% (117/120)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the vacuolar protein sorting-associated 13 gene family. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010]

Allele List at MGI

All alleles(13) : Targeted, other(2) Gene trapped(11)

Other mutations in this stock

Total: 114 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930503L19Rik	A	T	18: 70,601,134 (GRCm39)	S249R	possibly damaging	Het
Acadvl	T	A	11: 69,901,181 (GRCm39)	I638F	probably damaging	Het
Acnat2	T	A	4: 49,380,587 (GRCm39)	T264S	probably benign	Het
Acrv1	C	T	9: 36,605,551 (GRCm39)	Q33*	probably null	Het
Actrt3	T	A	3: 30,653,901 (GRCm39)	N33I	probably damaging	Het
Alyref2	T	C	1: 171,331,168 (GRCm39)		probably benign	Het
Ank2	C	A	3: 126,726,709 (GRCm39)	E3712*	probably null	Het
Ano7	C	A	1: 93,313,346 (GRCm39)	H161Q	probably benign	Het
Arhgap10	C	A	8: 78,085,216 (GRCm39)	E451*	probably null	Het
Arhgap29	T	A	3: 121,801,729 (GRCm39)	Y748N	probably damaging	Het
Arhgap45	C	T	10: 79,853,932 (GRCm39)	Q149*	probably null	Het
Asap2	C	T	12: 21,274,393 (GRCm39)	H371Y	probably damaging	Het
Atp6v1b1	T	C	6: 83,735,372 (GRCm39)	I480T	probably benign	Het
BC034090	T	C	1: 155,101,610 (GRCm39)	D218G	possibly damaging	Het
Brdt	A	T	5: 107,491,450 (GRCm39)	D74V	probably damaging	Het
C4b	A	G	17: 34,962,638 (GRCm39)		probably benign	Het
Card11	T	A	5: 140,888,660 (GRCm39)	K233*	probably null	Het
Catip	T	G	1: 74,401,929 (GRCm39)	F35V	possibly damaging	Het
Ccdc13	C	T	9: 121,648,647 (GRCm39)	G247R	probably damaging	Het
Cep97	T	A	16: 55,735,385 (GRCm39)	D471V	probably damaging	Het
Col17a1	A	T	19: 47,659,370 (GRCm39)	L403Q	probably damaging	Het
Crbn	A	G	6: 106,767,906 (GRCm39)	S194P	possibly damaging	Het
Degs1l	A	G	1: 180,878,884 (GRCm39)	M1V	probably null	Het
Dennd10	A	G	19: 60,806,021 (GRCm39)	Y102C	probably damaging	Het
Dhx58	T	A	11: 100,594,400 (GRCm39)	H97L	probably benign	Het
Dnah8	T	C	17: 31,073,914 (GRCm39)	I4528T	probably damaging	Het
Dpyd	A	G	3: 118,404,092 (GRCm39)		probably null	Het
Entpd1	A	T	19: 40,714,680 (GRCm39)	Q263L	probably benign	Het
Entrep1	A	T	19: 23,957,059 (GRCm39)	I317N	probably damaging	Het
Esyt3	T	C	9: 99,218,244 (GRCm39)	I130M	probably benign	Het
Etv1	T	C	12: 38,902,261 (GRCm39)	F264S	probably benign	Het
Fat1	T	C	8: 45,463,519 (GRCm39)	S1354P	probably benign	Het
Fat4	C	A	3: 39,005,304 (GRCm39)	T1901N	probably damaging	Het
Fbxw13	C	T	9: 109,010,586 (GRCm39)	V351I	probably damaging	Het
Fmo3	A	G	1: 162,795,356 (GRCm39)	F160L	possibly damaging	Het
Fyb2	T	A	4: 104,861,113 (GRCm39)	D592E	probably damaging	Het
Gjb4	T	C	4: 127,245,663 (GRCm39)	M93V	possibly damaging	Het
Gm5089	C	A	14: 122,673,566 (GRCm39)	G52*	probably null	Het
Gm6401	G	T	14: 41,788,840 (GRCm39)	N76K	probably benign	Het
Gm6871	A	G	7: 41,195,901 (GRCm39)	S279P	probably damaging	Het
Gtf2ird2	T	G	5: 134,240,081 (GRCm39)	V301G	probably benign	Het
H2bw2	A	C	X: 135,828,216 (GRCm39)	D35A	unknown	Het
Hfm1	A	G	5: 107,028,380 (GRCm39)	F817L	probably damaging	Het
Hfm1	T	C	5: 107,043,869 (GRCm39)	E589G	probably damaging	Het
Hivep2	A	T	10: 14,005,249 (GRCm39)	K616*	probably null	Het
Hmcn1	A	T	1: 150,551,735 (GRCm39)	I2623N	probably damaging	Het
Igf2bp3	G	T	6: 49,082,565 (GRCm39)	A339E	probably damaging	Het
Insyn2b	T	A	11: 34,354,263 (GRCm39)		probably null	Het
Irx4	T	C	13: 73,415,757 (GRCm39)	I182T	possibly damaging	Het
Jcad	T	C	18: 4,674,511 (GRCm39)	S758P	probably damaging	Het
Klhdc4	A	T	8: 122,526,226 (GRCm39)	Y304*	probably null	Het
Lama1	A	G	17: 68,060,786 (GRCm39)	I705V	probably benign	Het
Mbd5	A	G	2: 49,147,044 (GRCm39)	N418S	probably benign	Het
Mmp21	C	T	7: 133,279,014 (GRCm39)	V279I	probably damaging	Het
Morc4	A	C	X: 138,755,279 (GRCm39)	C272W	probably damaging	Het
Mrm1	A	T	11: 84,709,518 (GRCm39)	C180S	probably damaging	Het
Ncor1	T	C	11: 62,313,831 (GRCm39)	D103G	probably damaging	Het
Ndrg4	A	G	8: 96,437,314 (GRCm39)	D251G	probably damaging	Het
Ndufaf5	T	C	2: 140,035,522 (GRCm39)	V246A	possibly damaging	Het
Noa1	T	C	5: 77,457,572 (GRCm39)	E111G	possibly damaging	Het
Nod1	C	A	6: 54,921,044 (GRCm39)	V425F	probably damaging	Het
Nos1	A	T	5: 118,033,984 (GRCm39)	I369F	probably damaging	Het
Nsun5	C	T	5: 135,400,170 (GRCm39)	H98Y	probably damaging	Het
Optn	G	A	2: 5,057,941 (GRCm39)	T76I	possibly damaging	Het
Or14c39	G	A	7: 86,344,318 (GRCm39)	R218H	probably benign	Het
Or4k15c	C	G	14: 50,321,827 (GRCm39)	V104L	probably benign	Het
Or5k1b	A	G	16: 58,581,504 (GRCm39)	F12L	probably benign	Het
Or8d1b	A	G	9: 38,887,202 (GRCm39)	I77V	probably damaging	Het
Or8g28	T	C	9: 39,169,867 (GRCm39)	I37V	probably benign	Het
Or9g19	C	T	2: 85,600,199 (GRCm39)	T18I	probably benign	Het
Oscar	C	T	7: 3,614,855 (GRCm39)	W22*	probably null	Het
Palmd	T	A	3: 116,717,306 (GRCm39)	Y397F	probably damaging	Het
Plk1	A	G	7: 121,768,121 (GRCm39)	D447G	probably damaging	Het
Plscr5	T	A	9: 92,087,581 (GRCm39)	N183K	probably damaging	Het
Polk	T	G	13: 96,625,712 (GRCm39)	D364A	probably damaging	Het
Polr3d	T	C	14: 70,680,450 (GRCm39)	T36A	probably benign	Het
Ppp1r10	A	T	17: 36,237,428 (GRCm39)	R199S	probably damaging	Het
Prkcz	C	T	4: 155,346,969 (GRCm39)	D388N	probably damaging	Het
Prrc2b	T	C	2: 32,102,234 (GRCm39)	L769P	probably damaging	Het
Psg26	A	G	7: 18,213,966 (GRCm39)	V232A	probably damaging	Het
Pth2r	T	C	1: 65,375,997 (GRCm39)	V85A	possibly damaging	Het
Rbpms2	T	C	9: 65,566,494 (GRCm39)		probably benign	Het
Reps1	A	T	10: 17,994,698 (GRCm39)	D514V	possibly damaging	Het
Riok3	G	T	18: 12,276,018 (GRCm39)	R238L	probably benign	Het
Rnf19a	T	C	15: 36,244,353 (GRCm39)	Q569R	probably damaging	Het
Rorb	G	A	19: 18,937,865 (GRCm39)	T267I	probably damaging	Het
Rrm2b	A	T	15: 37,929,340 (GRCm39)	M70K	probably damaging	Het
Rsf1	A	T	7: 97,311,556 (GRCm39)	E762V	possibly damaging	Het
S100a2	G	A	3: 90,498,699 (GRCm39)	V67I	probably benign	Het
Skp1	T	A	11: 52,133,442 (GRCm39)	D42E	probably benign	Het
Slc22a4	A	T	11: 53,918,801 (GRCm39)	M1K	probably null	Het
Slc2a9	T	A	5: 38,539,387 (GRCm39)	Q371L	probably damaging	Het
Slc4a9	A	G	18: 36,665,075 (GRCm39)	T475A	probably benign	Het
Slc8b1	A	G	5: 120,657,717 (GRCm39)	N60S	probably damaging	Het
Slx4	A	C	16: 3,817,022 (GRCm39)	D66E	probably benign	Het
Smg8	A	T	11: 86,977,113 (GRCm39)	I156N	probably damaging	Het
Snx25	A	T	8: 46,569,244 (GRCm39)	C218S	possibly damaging	Het
Sulf2	T	C	2: 165,920,992 (GRCm39)	I784V	probably benign	Het
Tatdn2	G	T	6: 113,674,888 (GRCm39)	R72L	possibly damaging	Het
Tbc1d8	T	C	1: 39,445,918 (GRCm39)	D91G	possibly damaging	Het
Tifab	C	A	13: 56,324,433 (GRCm39)	R3S	probably benign	Het
Tm4sf1	A	T	3: 57,200,304 (GRCm39)	S104T	probably damaging	Het
Tmem132e	T	A	11: 82,334,343 (GRCm39)	I618N	probably damaging	Het
Ttc7b	A	T	12: 100,369,667 (GRCm39)	D367E	probably damaging	Het
Txlnb	A	G	10: 17,719,203 (GRCm39)	D678G	possibly damaging	Het
Vgll4	A	G	6: 114,934,895 (GRCm39)		probably null	Het
Vmn2r124	A	T	17: 18,282,187 (GRCm39)		probably benign	Het
Vmn2r2	T	C	3: 64,024,820 (GRCm39)	D587G	probably benign	Het
Vmn2r84	G	A	10: 130,226,968 (GRCm39)	A290V	probably benign	Het
Vsig10	C	T	5: 117,489,719 (GRCm39)	A495V	probably benign	Het
Vwa3a	A	T	7: 120,403,254 (GRCm39)		probably null	Het
Zfhx2	C	A	14: 55,303,455 (GRCm39)	A1510S	possibly damaging	Het
Zfp142	T	A	1: 74,611,389 (GRCm39)	D601V	probably damaging	Het
Zfp62	T	C	11: 49,108,510 (GRCm39)	I867T	probably benign	Het

Other mutations in Vps13c

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00159:Vps13c	APN	9	67,853,281 (GRCm39)	missense	probably benign	0.20
IGL00336:Vps13c	APN	9	67,853,224 (GRCm39)	missense	probably benign	0.01
IGL00418:Vps13c	APN	9	67,783,544 (GRCm39)	missense	probably damaging	1.00
IGL00481:Vps13c	APN	9	67,768,147 (GRCm39)	missense	probably damaging	1.00
IGL00491:Vps13c	APN	9	67,800,418 (GRCm39)	missense	probably damaging	1.00
IGL00558:Vps13c	APN	9	67,845,139 (GRCm39)	missense	possibly damaging	0.52
IGL00811:Vps13c	APN	9	67,855,463 (GRCm39)	missense	probably damaging	0.99
IGL01011:Vps13c	APN	9	67,834,237 (GRCm39)	missense	probably damaging	0.98
IGL01094:Vps13c	APN	9	67,793,566 (GRCm39)	missense	probably damaging	1.00
IGL01330:Vps13c	APN	9	67,871,390 (GRCm39)	missense	probably damaging	1.00
IGL01402:Vps13c	APN	9	67,820,486 (GRCm39)	critical splice acceptor site	probably null
IGL01404:Vps13c	APN	9	67,820,486 (GRCm39)	critical splice acceptor site	probably null
IGL01470:Vps13c	APN	9	67,820,209 (GRCm39)	splice site	probably benign
IGL01615:Vps13c	APN	9	67,863,063 (GRCm39)	missense	probably benign	0.01
IGL01694:Vps13c	APN	9	67,802,631 (GRCm39)	missense	probably damaging	1.00
IGL01752:Vps13c	APN	9	67,855,510 (GRCm39)	missense	probably damaging	1.00
IGL01810:Vps13c	APN	9	67,863,062 (GRCm39)	missense	probably benign
IGL01954:Vps13c	APN	9	67,876,580 (GRCm39)	missense	probably damaging	0.98
IGL01978:Vps13c	APN	9	67,837,925 (GRCm39)	missense	probably benign	0.03
IGL01998:Vps13c	APN	9	67,862,350 (GRCm39)	splice site	probably null
IGL02201:Vps13c	APN	9	67,874,418 (GRCm39)	missense	probably damaging	1.00
IGL02205:Vps13c	APN	9	67,790,736 (GRCm39)	missense	probably damaging	1.00
IGL02303:Vps13c	APN	9	67,852,763 (GRCm39)	splice site	probably benign
IGL02322:Vps13c	APN	9	67,845,183 (GRCm39)	missense	probably benign	0.02
IGL02456:Vps13c	APN	9	67,860,258 (GRCm39)	missense	probably damaging	1.00
IGL02474:Vps13c	APN	9	67,845,158 (GRCm39)	missense	probably benign	0.00
IGL02547:Vps13c	APN	9	67,815,301 (GRCm39)	missense	possibly damaging	0.83
IGL02640:Vps13c	APN	9	67,793,530 (GRCm39)	splice site	probably benign
IGL02673:Vps13c	APN	9	67,785,380 (GRCm39)	missense	probably damaging	1.00
IGL02721:Vps13c	APN	9	67,871,431 (GRCm39)	splice site	probably benign
IGL02834:Vps13c	APN	9	67,845,137 (GRCm39)	missense	probably benign
IGL02838:Vps13c	APN	9	67,883,133 (GRCm39)	missense	probably damaging	1.00
IGL03136:Vps13c	APN	9	67,857,592 (GRCm39)	missense	probably damaging	1.00
IGL03137:Vps13c	APN	9	67,797,662 (GRCm39)	missense	probably damaging	1.00
IGL03214:Vps13c	APN	9	67,804,477 (GRCm39)	missense	probably null	0.81
IGL03240:Vps13c	APN	9	67,862,329 (GRCm39)	missense	probably benign
IGL03303:Vps13c	APN	9	67,841,786 (GRCm39)	missense	probably benign	0.27
IGL03336:Vps13c	APN	9	67,858,924 (GRCm39)	missense	possibly damaging	0.76
IGL03366:Vps13c	APN	9	67,853,308 (GRCm39)	missense	probably benign	0.00
Derivative	UTSW	9	67,837,904 (GRCm39)	missense	possibly damaging	0.79
diversion	UTSW	9	67,817,515 (GRCm39)	missense	possibly damaging	0.93
introversion	UTSW	9	67,851,328 (GRCm39)	missense	probably damaging	0.98
Inversion	UTSW	9	67,810,121 (GRCm39)	critical splice acceptor site	probably null
subversion	UTSW	9	67,815,334 (GRCm39)	missense	probably damaging	1.00
Transversion	UTSW	9	67,841,783 (GRCm39)	missense	probably damaging	0.98
3-1:Vps13c	UTSW	9	67,843,655 (GRCm39)	missense	probably benign	0.00
IGL02991:Vps13c	UTSW	9	67,821,159 (GRCm39)	missense	probably damaging	1.00
PIT4802001:Vps13c	UTSW	9	67,845,068 (GRCm39)	missense	probably damaging	1.00
R0008:Vps13c	UTSW	9	67,826,544 (GRCm39)	missense	probably benign
R0206:Vps13c	UTSW	9	67,846,444 (GRCm39)	splice site	probably benign
R0288:Vps13c	UTSW	9	67,834,648 (GRCm39)	missense	probably damaging	0.99
R0324:Vps13c	UTSW	9	67,871,591 (GRCm39)	missense	possibly damaging	0.95
R0347:Vps13c	UTSW	9	67,817,515 (GRCm39)	missense	possibly damaging	0.93
R0374:Vps13c	UTSW	9	67,793,528 (GRCm39)	splice site	probably benign
R0388:Vps13c	UTSW	9	67,830,197 (GRCm39)	splice site	probably benign
R0409:Vps13c	UTSW	9	67,858,926 (GRCm39)	missense	probably benign	0.00
R0440:Vps13c	UTSW	9	67,880,143 (GRCm39)	missense	probably damaging	1.00
R0513:Vps13c	UTSW	9	67,838,017 (GRCm39)	missense	probably benign	0.02
R0520:Vps13c	UTSW	9	67,853,133 (GRCm39)	missense	possibly damaging	0.88
R0569:Vps13c	UTSW	9	67,881,001 (GRCm39)	missense	probably damaging	0.98
R0601:Vps13c	UTSW	9	67,834,754 (GRCm39)	missense	probably benign	0.12
R0659:Vps13c	UTSW	9	67,828,217 (GRCm39)	missense	probably benign	0.11
R0667:Vps13c	UTSW	9	67,858,855 (GRCm39)	nonsense	probably null
R0670:Vps13c	UTSW	9	67,833,139 (GRCm39)	missense	probably benign	0.35
R0698:Vps13c	UTSW	9	67,797,005 (GRCm39)	missense	probably benign	0.45
R0729:Vps13c	UTSW	9	67,868,931 (GRCm39)	missense	probably damaging	1.00
R0781:Vps13c	UTSW	9	67,879,285 (GRCm39)	missense	probably damaging	1.00
R0811:Vps13c	UTSW	9	67,841,758 (GRCm39)	missense	probably benign	0.06
R0812:Vps13c	UTSW	9	67,841,758 (GRCm39)	missense	probably benign	0.06
R0839:Vps13c	UTSW	9	67,806,020 (GRCm39)	missense	probably benign
R1373:Vps13c	UTSW	9	67,834,793 (GRCm39)	missense	probably damaging	0.99
R1396:Vps13c	UTSW	9	67,862,304 (GRCm39)	missense	probably benign	0.00
R1499:Vps13c	UTSW	9	67,864,787 (GRCm39)	missense	probably benign	0.00
R1556:Vps13c	UTSW	9	67,837,993 (GRCm39)	missense	probably damaging	0.98
R1560:Vps13c	UTSW	9	67,843,745 (GRCm39)	critical splice donor site	probably null
R1584:Vps13c	UTSW	9	67,800,394 (GRCm39)	missense	possibly damaging	0.74
R1654:Vps13c	UTSW	9	67,858,969 (GRCm39)	missense	probably damaging	1.00
R1674:Vps13c	UTSW	9	67,760,985 (GRCm39)	nonsense	probably null
R1676:Vps13c	UTSW	9	67,834,244 (GRCm39)	missense	probably benign	0.20
R1695:Vps13c	UTSW	9	67,879,357 (GRCm39)	nonsense	probably null
R1769:Vps13c	UTSW	9	67,873,003 (GRCm39)	missense	probably benign	0.00
R1775:Vps13c	UTSW	9	67,788,729 (GRCm39)	missense	probably damaging	1.00
R1795:Vps13c	UTSW	9	67,801,267 (GRCm39)	nonsense	probably null
R1799:Vps13c	UTSW	9	67,851,399 (GRCm39)	missense	probably damaging	0.98
R1835:Vps13c	UTSW	9	67,900,295 (GRCm39)	missense	probably benign	0.08
R1848:Vps13c	UTSW	9	67,843,622 (GRCm39)	missense	probably benign
R1903:Vps13c	UTSW	9	67,801,334 (GRCm39)	missense	probably damaging	1.00
R1944:Vps13c	UTSW	9	67,793,558 (GRCm39)	missense	probably damaging	1.00
R1945:Vps13c	UTSW	9	67,793,558 (GRCm39)	missense	probably damaging	1.00
R1951:Vps13c	UTSW	9	67,881,041 (GRCm39)	critical splice donor site	probably null
R1993:Vps13c	UTSW	9	67,883,138 (GRCm39)	missense	probably damaging	1.00
R2023:Vps13c	UTSW	9	67,843,567 (GRCm39)	splice site	probably benign
R2059:Vps13c	UTSW	9	67,768,115 (GRCm39)	missense	probably damaging	1.00
R2086:Vps13c	UTSW	9	67,857,571 (GRCm39)	missense	probably benign	0.29
R2120:Vps13c	UTSW	9	67,826,616 (GRCm39)	missense	possibly damaging	0.92
R2249:Vps13c	UTSW	9	67,895,335 (GRCm39)	critical splice donor site	probably null
R2257:Vps13c	UTSW	9	67,860,228 (GRCm39)	missense	possibly damaging	0.87
R2258:Vps13c	UTSW	9	67,861,142 (GRCm39)	missense	probably benign	0.01
R2259:Vps13c	UTSW	9	67,861,142 (GRCm39)	missense	probably benign	0.01
R2260:Vps13c	UTSW	9	67,861,142 (GRCm39)	missense	probably benign	0.01
R2265:Vps13c	UTSW	9	67,828,229 (GRCm39)	missense	possibly damaging	0.82
R2266:Vps13c	UTSW	9	67,828,229 (GRCm39)	missense	possibly damaging	0.82
R2269:Vps13c	UTSW	9	67,828,229 (GRCm39)	missense	possibly damaging	0.82
R2278:Vps13c	UTSW	9	67,846,354 (GRCm39)	missense	probably benign
R2306:Vps13c	UTSW	9	67,895,275 (GRCm39)	missense	probably damaging	0.99
R2327:Vps13c	UTSW	9	67,821,102 (GRCm39)	missense	probably damaging	0.98
R2349:Vps13c	UTSW	9	67,864,808 (GRCm39)	missense	possibly damaging	0.89
R2483:Vps13c	UTSW	9	67,883,189 (GRCm39)	critical splice donor site	probably null
R3031:Vps13c	UTSW	9	67,831,052 (GRCm39)	missense	probably benign	0.00
R3623:Vps13c	UTSW	9	67,883,189 (GRCm39)	critical splice donor site	probably null
R3870:Vps13c	UTSW	9	67,792,008 (GRCm39)	missense	probably benign	0.00
R4173:Vps13c	UTSW	9	67,843,595 (GRCm39)	missense	probably benign	0.00
R4445:Vps13c	UTSW	9	67,889,777 (GRCm39)	splice site	probably null
R4491:Vps13c	UTSW	9	67,817,475 (GRCm39)	missense	probably benign
R4505:Vps13c	UTSW	9	67,846,316 (GRCm39)	missense	probably benign	0.02
R4574:Vps13c	UTSW	9	67,858,965 (GRCm39)	missense	probably damaging	1.00
R4691:Vps13c	UTSW	9	67,860,217 (GRCm39)	missense	possibly damaging	0.95
R4766:Vps13c	UTSW	9	67,785,506 (GRCm39)	splice site	probably null
R4771:Vps13c	UTSW	9	67,836,821 (GRCm39)	missense	probably benign
R4801:Vps13c	UTSW	9	67,871,564 (GRCm39)	missense	probably damaging	1.00
R4802:Vps13c	UTSW	9	67,871,564 (GRCm39)	missense	probably damaging	1.00
R4962:Vps13c	UTSW	9	67,781,173 (GRCm39)	missense	probably damaging	1.00
R4995:Vps13c	UTSW	9	67,826,603 (GRCm39)	missense	probably benign	0.00
R5010:Vps13c	UTSW	9	67,823,661 (GRCm39)	missense	probably benign	0.19
R5183:Vps13c	UTSW	9	67,815,334 (GRCm39)	missense	probably damaging	1.00
R5226:Vps13c	UTSW	9	67,852,835 (GRCm39)	missense	probably benign	0.17
R5297:Vps13c	UTSW	9	67,785,413 (GRCm39)	missense	probably damaging	1.00
R5456:Vps13c	UTSW	9	67,834,729 (GRCm39)	missense	possibly damaging	0.53
R5494:Vps13c	UTSW	9	67,855,428 (GRCm39)	missense	probably benign	0.00
R5521:Vps13c	UTSW	9	67,858,721 (GRCm39)	missense	probably benign	0.08
R5524:Vps13c	UTSW	9	67,864,838 (GRCm39)	missense	probably damaging	1.00
R5685:Vps13c	UTSW	9	67,870,455 (GRCm39)	missense	possibly damaging	0.64
R5731:Vps13c	UTSW	9	67,802,661 (GRCm39)	missense	probably damaging	1.00
R5812:Vps13c	UTSW	9	67,889,777 (GRCm39)	splice site	probably benign
R5867:Vps13c	UTSW	9	67,889,904 (GRCm39)	splice site	probably null
R5893:Vps13c	UTSW	9	67,810,121 (GRCm39)	critical splice acceptor site	probably null
R5902:Vps13c	UTSW	9	67,841,729 (GRCm39)	missense	probably benign	0.00
R5957:Vps13c	UTSW	9	67,862,253 (GRCm39)	missense	probably damaging	1.00
R6076:Vps13c	UTSW	9	67,818,884 (GRCm39)	missense	probably damaging	1.00
R6187:Vps13c	UTSW	9	67,822,939 (GRCm39)	missense	probably damaging	1.00
R6268:Vps13c	UTSW	9	67,858,731 (GRCm39)	missense	probably benign	0.10
R6547:Vps13c	UTSW	9	67,880,647 (GRCm39)	missense	probably damaging	1.00
R6716:Vps13c	UTSW	9	67,858,749 (GRCm39)	missense	probably benign	0.00
R6837:Vps13c	UTSW	9	67,817,504 (GRCm39)	missense	probably benign
R6919:Vps13c	UTSW	9	67,834,734 (GRCm39)	missense	probably damaging	0.97
R7039:Vps13c	UTSW	9	67,845,045 (GRCm39)	missense	probably damaging	1.00
R7058:Vps13c	UTSW	9	67,831,110 (GRCm39)	missense	probably benign	0.39
R7082:Vps13c	UTSW	9	67,790,735 (GRCm39)	missense	probably damaging	1.00
R7195:Vps13c	UTSW	9	67,853,107 (GRCm39)	missense	possibly damaging	0.95
R7244:Vps13c	UTSW	9	67,797,086 (GRCm39)	missense	probably benign	0.00
R7300:Vps13c	UTSW	9	67,847,826 (GRCm39)	missense	probably benign	0.20
R7314:Vps13c	UTSW	9	67,850,622 (GRCm39)	splice site	probably null
R7352:Vps13c	UTSW	9	67,747,728 (GRCm39)	missense	possibly damaging	0.94
R7368:Vps13c	UTSW	9	67,821,355 (GRCm39)	missense	probably benign	0.23
R7411:Vps13c	UTSW	9	67,879,283 (GRCm39)	missense	probably damaging	0.98
R7497:Vps13c	UTSW	9	67,747,761 (GRCm39)	missense	probably damaging	1.00
R7516:Vps13c	UTSW	9	67,862,289 (GRCm39)	missense	possibly damaging	0.89
R7638:Vps13c	UTSW	9	67,852,791 (GRCm39)	missense	probably damaging	1.00
R7732:Vps13c	UTSW	9	67,847,798 (GRCm39)	missense	probably damaging	0.97
R7748:Vps13c	UTSW	9	67,870,371 (GRCm39)	missense	probably benign	0.03
R7779:Vps13c	UTSW	9	67,788,704 (GRCm39)	missense	probably damaging	1.00
R7788:Vps13c	UTSW	9	67,847,765 (GRCm39)	missense	probably benign	0.01
R7894:Vps13c	UTSW	9	67,834,265 (GRCm39)	missense	probably damaging	0.99
R8163:Vps13c	UTSW	9	67,857,720 (GRCm39)	missense	probably benign	0.08
R8165:Vps13c	UTSW	9	67,766,072 (GRCm39)	missense	probably benign	0.00
R8202:Vps13c	UTSW	9	67,851,328 (GRCm39)	missense	probably damaging	0.98
R8235:Vps13c	UTSW	9	67,863,063 (GRCm39)	missense	probably benign	0.01
R8235:Vps13c	UTSW	9	67,834,678 (GRCm39)	missense	probably damaging	1.00
R8253:Vps13c	UTSW	9	67,850,770 (GRCm39)	nonsense	probably null
R8261:Vps13c	UTSW	9	67,862,262 (GRCm39)	missense	probably damaging	1.00
R8348:Vps13c	UTSW	9	67,786,385 (GRCm39)	missense	possibly damaging	0.79
R8547:Vps13c	UTSW	9	67,852,848 (GRCm39)	missense	probably damaging	1.00
R8734:Vps13c	UTSW	9	67,880,685 (GRCm39)	missense	probably damaging	1.00
R8806:Vps13c	UTSW	9	67,853,110 (GRCm39)	missense	probably damaging	1.00
R8807:Vps13c	UTSW	9	67,766,122 (GRCm39)	missense	probably damaging	0.99
R8813:Vps13c	UTSW	9	67,778,566 (GRCm39)	missense	probably damaging	1.00
R8883:Vps13c	UTSW	9	67,855,479 (GRCm39)	missense	probably benign	0.10
R8885:Vps13c	UTSW	9	67,850,736 (GRCm39)	missense	probably benign
R8899:Vps13c	UTSW	9	67,841,783 (GRCm39)	missense	probably damaging	0.98
R8970:Vps13c	UTSW	9	67,852,803 (GRCm39)	missense	probably benign	0.11
R9007:Vps13c	UTSW	9	67,845,006 (GRCm39)	missense	probably benign	0.00
R9026:Vps13c	UTSW	9	67,861,863 (GRCm39)	missense	probably damaging	1.00
R9029:Vps13c	UTSW	9	67,855,429 (GRCm39)	missense	probably damaging	0.98
R9057:Vps13c	UTSW	9	67,828,209 (GRCm39)	missense	probably benign	0.00
R9105:Vps13c	UTSW	9	67,778,081 (GRCm39)	intron	probably benign
R9130:Vps13c	UTSW	9	67,836,805 (GRCm39)	missense	probably damaging	1.00
R9286:Vps13c	UTSW	9	67,880,203 (GRCm39)	missense	probably benign	0.00
R9338:Vps13c	UTSW	9	67,858,977 (GRCm39)	missense	probably damaging	1.00
R9432:Vps13c	UTSW	9	67,830,137 (GRCm39)	missense	probably benign	0.02
R9460:Vps13c	UTSW	9	67,837,904 (GRCm39)	missense	possibly damaging	0.79
R9464:Vps13c	UTSW	9	67,858,674 (GRCm39)	missense	probably damaging	1.00
R9561:Vps13c	UTSW	9	67,872,794 (GRCm39)	missense	probably damaging	1.00
R9609:Vps13c	UTSW	9	67,841,831 (GRCm39)	missense	probably damaging	1.00
R9622:Vps13c	UTSW	9	67,856,715 (GRCm39)	missense	probably damaging	1.00
R9665:Vps13c	UTSW	9	67,863,025 (GRCm39)	nonsense	probably null
R9731:Vps13c	UTSW	9	67,826,526 (GRCm39)	missense	probably benign
R9763:Vps13c	UTSW	9	67,818,860 (GRCm39)	missense	probably benign	0.00
R9774:Vps13c	UTSW	9	67,791,873 (GRCm39)	missense	possibly damaging	0.85
R9798:Vps13c	UTSW	9	67,826,646 (GRCm39)	missense	probably damaging	1.00
U24488:Vps13c	UTSW	9	67,813,198 (GRCm39)	missense	probably benign	0.13
X0021:Vps13c	UTSW	9	67,845,063 (GRCm39)	missense	probably damaging	0.99
X0058:Vps13c	UTSW	9	67,834,701 (GRCm39)	missense	probably damaging	1.00
X0065:Vps13c	UTSW	9	67,781,145 (GRCm39)	missense	probably damaging	1.00
Z1088:Vps13c	UTSW	9	67,821,257 (GRCm39)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- GGCAGGGACTATTTGCATCTTTGAAAC -3'
(R):5'- TCCTCTAATCCTAAGCATCCAGTCCAG -3'

Sequencing Primer
(F):5'- gttgagaatccctagaatttgaatcc -3'
(R):5'- TGTGTGCAGTTCAGAGCCC -3'

Posted On

2014-05-14