Incidental Mutation 'R1964:Ddx60'
| ID |
217107 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ddx60
|
| Ensembl Gene |
ENSMUSG00000037921 |
| Gene Name |
DExD/H box helicase 60 |
| Synonyms |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| MMRRC Submission |
039977-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.215)
|
| Stock # |
R1964 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
8 |
| Chromosomal Location |
62381121-62490735 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 62401903 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Serine
at position 260
(C260S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000122841
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000070631]
[ENSMUST00000093485]
[ENSMUST00000154398]
|
| AlphaFold |
E9PZQ1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000070631
AA Change: C260S
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000070741
Gene: ENSMUSG00000037921
AA Change: C260S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
758 |
949 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1007 |
1132 |
4e-24 |
BLAST |
|
HELICc
|
1245 |
1328 |
4.35e-13 |
SMART |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1503 |
1584 |
1e-20 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000093485
AA Change: C260S
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000091197
Gene: ENSMUSG00000037921
AA Change: C260S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
DEXDc
|
759 |
950 |
1.05e-15 |
SMART |
|
Blast:DEXDc
|
1008 |
1133 |
4e-24 |
BLAST |
|
HELICc
|
1246 |
1329 |
4.35e-13 |
SMART |
|
low complexity region
|
1363 |
1374 |
N/A |
INTRINSIC |
|
Blast:DEXDc
|
1504 |
1585 |
1e-20 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000154398
AA Change: C260S
PolyPhen 2
Score 0.097 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000122841
Gene: ENSMUSG00000037921
AA Change: C260S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
99 |
110 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
376 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 94.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal immunity to several viruses (IAV, EMCV, SINV) but increased susceptibility to VSV infection. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700010I14Rik |
C |
T |
17: 9,211,324 (GRCm39) |
H158Y |
probably damaging |
Het |
| 1810009J06Rik |
T |
A |
6: 40,945,141 (GRCm39) |
C207S |
probably damaging |
Het |
| Aadac |
T |
A |
3: 59,944,759 (GRCm39) |
|
probably null |
Het |
| Abca6 |
T |
A |
11: 110,075,502 (GRCm39) |
I1330F |
probably damaging |
Het |
| Adar |
A |
T |
3: 89,653,202 (GRCm39) |
S263C |
probably benign |
Het |
| Adra2b |
T |
C |
2: 127,205,734 (GRCm39) |
Y84H |
probably damaging |
Het |
| Arnt2 |
A |
T |
7: 83,992,997 (GRCm39) |
V181E |
possibly damaging |
Het |
| Atg7 |
T |
C |
6: 114,683,191 (GRCm39) |
L418P |
probably damaging |
Het |
| Atp2c1 |
A |
G |
9: 105,323,322 (GRCm39) |
L181P |
probably damaging |
Het |
| Awat2 |
G |
A |
X: 99,448,165 (GRCm39) |
P148S |
probably damaging |
Het |
| Birc6 |
A |
G |
17: 74,941,880 (GRCm39) |
M2737V |
possibly damaging |
Het |
| Ccdc81 |
A |
G |
7: 89,535,361 (GRCm39) |
C292R |
probably benign |
Het |
| Cd14 |
T |
A |
18: 36,859,392 (GRCm39) |
E21V |
probably damaging |
Het |
| Cdc14b |
A |
C |
13: 64,363,351 (GRCm39) |
C303W |
probably damaging |
Het |
| Cdh23 |
T |
C |
10: 60,221,001 (GRCm39) |
I1248V |
probably benign |
Het |
| Ceacam1 |
T |
C |
7: 25,174,133 (GRCm39) |
D174G |
probably benign |
Het |
| Cgas |
T |
G |
9: 78,344,737 (GRCm39) |
Y228S |
probably damaging |
Het |
| Chd7 |
A |
G |
4: 8,865,978 (GRCm39) |
M717V |
probably damaging |
Het |
| Cib1 |
T |
C |
7: 79,882,120 (GRCm39) |
T20A |
possibly damaging |
Het |
| Clec4d |
A |
G |
6: 123,239,319 (GRCm39) |
K9R |
probably benign |
Het |
| Cntnap1 |
C |
A |
11: 101,068,850 (GRCm39) |
S131* |
probably null |
Het |
| Crybg1 |
T |
C |
10: 43,834,326 (GRCm39) |
K1581R |
probably damaging |
Het |
| Csf2 |
T |
G |
11: 54,139,284 (GRCm39) |
T100P |
probably benign |
Het |
| Csrp2 |
T |
A |
10: 110,767,894 (GRCm39) |
D26E |
probably benign |
Het |
| Cul1 |
T |
C |
6: 47,479,505 (GRCm39) |
V257A |
probably damaging |
Het |
| Cul4a |
G |
A |
8: 13,186,406 (GRCm39) |
M505I |
possibly damaging |
Het |
| Cul4a |
T |
C |
8: 13,186,854 (GRCm39) |
M530T |
probably benign |
Het |
| Dcp2 |
T |
C |
18: 44,529,038 (GRCm39) |
M51T |
possibly damaging |
Het |
| Dennd2c |
G |
A |
3: 103,073,807 (GRCm39) |
R851H |
probably damaging |
Het |
| Dnah11 |
T |
C |
12: 118,106,027 (GRCm39) |
E625G |
possibly damaging |
Het |
| Edem1 |
T |
C |
6: 108,821,908 (GRCm39) |
W322R |
probably benign |
Het |
| Egflam |
T |
C |
15: 7,276,586 (GRCm39) |
T527A |
probably damaging |
Het |
| Ephb1 |
T |
A |
9: 101,848,322 (GRCm39) |
M659L |
possibly damaging |
Het |
| Fbxl2 |
A |
G |
9: 113,818,237 (GRCm39) |
I203T |
probably benign |
Het |
| Gabbr1 |
G |
A |
17: 37,359,351 (GRCm39) |
G109R |
probably damaging |
Het |
| Gabra2 |
T |
C |
5: 71,171,793 (GRCm39) |
I148V |
possibly damaging |
Het |
| Golga1 |
A |
G |
2: 38,937,099 (GRCm39) |
V161A |
probably benign |
Het |
| Gps2 |
T |
G |
11: 69,807,246 (GRCm39) |
S301A |
probably benign |
Het |
| H2-D1 |
T |
C |
17: 35,482,595 (GRCm39) |
L105P |
probably benign |
Het |
| Igdcc4 |
T |
C |
9: 65,030,051 (GRCm39) |
V367A |
probably benign |
Het |
| Igkv4-69 |
T |
G |
6: 69,260,782 (GRCm39) |
Y115S |
probably benign |
Het |
| Itga5 |
A |
G |
15: 103,262,741 (GRCm39) |
L309P |
probably damaging |
Het |
| Itih1 |
A |
G |
14: 30,651,580 (GRCm39) |
Y871H |
probably damaging |
Het |
| Itpr2 |
T |
A |
6: 146,013,191 (GRCm39) |
N2662I |
probably damaging |
Het |
| Kctd19 |
T |
A |
8: 106,115,102 (GRCm39) |
E486D |
probably damaging |
Het |
| Kif5b |
C |
T |
18: 6,209,059 (GRCm39) |
R901Q |
possibly damaging |
Het |
| Kmt2a |
G |
A |
9: 44,731,941 (GRCm39) |
S2792F |
probably benign |
Het |
| Magi3 |
A |
G |
3: 103,927,718 (GRCm39) |
V1023A |
probably damaging |
Het |
| Mapk9 |
C |
A |
11: 49,745,160 (GRCm39) |
R25S |
probably null |
Het |
| Memo1 |
T |
C |
17: 74,552,003 (GRCm39) |
T98A |
possibly damaging |
Het |
| Mill2 |
A |
G |
7: 18,590,529 (GRCm39) |
K203R |
probably damaging |
Het |
| Mios |
T |
A |
6: 8,215,798 (GRCm39) |
H331Q |
probably damaging |
Het |
| Muc6 |
G |
T |
7: 141,226,329 (GRCm39) |
S1566* |
probably null |
Het |
| Muc6 |
A |
G |
7: 141,226,330 (GRCm39) |
|
probably benign |
Het |
| Napsa |
T |
C |
7: 44,231,109 (GRCm39) |
F113L |
probably benign |
Het |
| Or5ac16 |
T |
A |
16: 59,022,271 (GRCm39) |
I173F |
possibly damaging |
Het |
| Or9m1 |
A |
G |
2: 87,734,011 (GRCm39) |
V3A |
probably benign |
Het |
| Oscp1 |
T |
G |
4: 125,977,415 (GRCm39) |
V226G |
possibly damaging |
Het |
| Osgin2 |
G |
T |
4: 15,998,358 (GRCm39) |
S421R |
probably damaging |
Het |
| Pclaf |
A |
G |
9: 65,800,677 (GRCm39) |
N50D |
probably damaging |
Het |
| Pdgfc |
A |
T |
3: 81,082,292 (GRCm39) |
I162F |
probably benign |
Het |
| Plag1 |
T |
C |
4: 3,903,956 (GRCm39) |
T412A |
probably benign |
Het |
| Pogz |
A |
T |
3: 94,785,504 (GRCm39) |
T820S |
probably benign |
Het |
| Ptpn9 |
T |
A |
9: 56,967,196 (GRCm39) |
V473D |
probably damaging |
Het |
| Qdpr |
A |
T |
5: 45,596,660 (GRCm39) |
M66K |
possibly damaging |
Het |
| Qrich1 |
A |
G |
9: 108,411,621 (GRCm39) |
N382S |
possibly damaging |
Het |
| Rbbp8 |
T |
C |
18: 11,875,736 (GRCm39) |
V883A |
possibly damaging |
Het |
| Rgl1 |
T |
A |
1: 152,424,855 (GRCm39) |
I375F |
probably damaging |
Het |
| Rif1 |
C |
T |
2: 51,988,421 (GRCm39) |
T720I |
probably benign |
Het |
| Rilp |
A |
T |
11: 75,401,328 (GRCm39) |
Q95L |
probably benign |
Het |
| Rnf169 |
T |
A |
7: 99,574,732 (GRCm39) |
N621I |
probably damaging |
Het |
| Rps27a |
T |
C |
11: 29,497,229 (GRCm39) |
K27R |
probably null |
Het |
| Sar1a |
T |
C |
10: 61,520,947 (GRCm39) |
V54A |
probably benign |
Het |
| Sash1 |
T |
A |
10: 8,605,477 (GRCm39) |
H971L |
probably benign |
Het |
| Sdk2 |
G |
A |
11: 113,671,843 (GRCm39) |
Q2102* |
probably null |
Het |
| Serpina1e |
T |
A |
12: 103,917,466 (GRCm39) |
I68F |
probably damaging |
Het |
| Serpinb9e |
A |
C |
13: 33,437,474 (GRCm39) |
Q119P |
probably benign |
Het |
| Sh3tc2 |
A |
T |
18: 62,124,226 (GRCm39) |
K965* |
probably null |
Het |
| Slc16a1 |
A |
T |
3: 104,556,782 (GRCm39) |
S56C |
probably damaging |
Het |
| Slc26a11 |
T |
A |
11: 119,271,020 (GRCm39) |
L563Q |
possibly damaging |
Het |
| Smarca2 |
G |
T |
19: 26,650,124 (GRCm39) |
E24* |
probably null |
Het |
| Smgc |
G |
A |
15: 91,744,468 (GRCm39) |
G239D |
probably damaging |
Het |
| Sos2 |
A |
T |
12: 69,663,636 (GRCm39) |
M616K |
possibly damaging |
Het |
| Tet1 |
T |
A |
10: 62,648,726 (GRCm39) |
D1902V |
possibly damaging |
Het |
| Thap2 |
C |
T |
10: 115,220,152 (GRCm39) |
C10Y |
probably damaging |
Het |
| Tln2 |
T |
C |
9: 67,249,417 (GRCm39) |
D890G |
probably benign |
Het |
| Tor2a |
G |
A |
2: 32,648,716 (GRCm39) |
G62D |
probably damaging |
Het |
| Ubqln5 |
A |
T |
7: 103,778,095 (GRCm39) |
V243E |
possibly damaging |
Het |
| Utrn |
A |
T |
10: 12,560,181 (GRCm39) |
D1369E |
probably damaging |
Het |
| Vcan |
A |
G |
13: 89,840,861 (GRCm39) |
V1561A |
probably benign |
Het |
| Vmn1r70 |
T |
C |
7: 10,367,737 (GRCm39) |
F56S |
possibly damaging |
Het |
| Vmn2r25 |
A |
G |
6: 123,800,254 (GRCm39) |
L696S |
possibly damaging |
Het |
| Washc2 |
A |
G |
6: 116,185,948 (GRCm39) |
T53A |
probably damaging |
Het |
| Wnk1 |
T |
A |
6: 119,911,343 (GRCm39) |
T2417S |
possibly damaging |
Het |
| Zbtb49 |
A |
T |
5: 38,361,105 (GRCm39) |
C12* |
probably null |
Het |
| Zfp472 |
C |
A |
17: 33,196,848 (GRCm39) |
P308T |
possibly damaging |
Het |
|
| Other mutations in Ddx60 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00340:Ddx60
|
APN |
8 |
62,411,680 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00915:Ddx60
|
APN |
8 |
62,440,465 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
IGL00931:Ddx60
|
APN |
8 |
62,422,617 (GRCm39) |
missense |
probably benign |
0.18 |
|
IGL01023:Ddx60
|
APN |
8 |
62,395,548 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01313:Ddx60
|
APN |
8 |
62,435,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01615:Ddx60
|
APN |
8 |
62,416,774 (GRCm39) |
missense |
probably null |
0.81 |
|
IGL01733:Ddx60
|
APN |
8 |
62,436,899 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01779:Ddx60
|
APN |
8 |
62,470,857 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01900:Ddx60
|
APN |
8 |
62,453,743 (GRCm39) |
splice site |
probably benign |
|
|
IGL02110:Ddx60
|
APN |
8 |
62,470,281 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02302:Ddx60
|
APN |
8 |
62,428,866 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02468:Ddx60
|
APN |
8 |
62,411,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02569:Ddx60
|
APN |
8 |
62,477,985 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL02622:Ddx60
|
APN |
8 |
62,395,470 (GRCm39) |
splice site |
probably null |
|
|
IGL02657:Ddx60
|
APN |
8 |
62,437,149 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02677:Ddx60
|
APN |
8 |
62,441,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02701:Ddx60
|
APN |
8 |
62,432,375 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02806:Ddx60
|
APN |
8 |
62,409,156 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03137:Ddx60
|
APN |
8 |
62,441,117 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL03295:Ddx60
|
APN |
8 |
62,409,155 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL03387:Ddx60
|
APN |
8 |
62,465,483 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03411:Ddx60
|
APN |
8 |
62,430,916 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Scatter
|
UTSW |
8 |
62,474,348 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
shotgun
|
UTSW |
8 |
62,490,101 (GRCm39) |
missense |
probably benign |
0.28 |
|
splay
|
UTSW |
8 |
62,474,343 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
G1Funyon:Ddx60
|
UTSW |
8 |
62,453,631 (GRCm39) |
missense |
probably benign |
0.01 |
|
PIT4504001:Ddx60
|
UTSW |
8 |
62,411,147 (GRCm39) |
missense |
probably benign |
|
|
PIT4677001:Ddx60
|
UTSW |
8 |
62,425,288 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R0090:Ddx60
|
UTSW |
8 |
62,395,327 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0266:Ddx60
|
UTSW |
8 |
62,486,527 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0325:Ddx60
|
UTSW |
8 |
62,436,889 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0367:Ddx60
|
UTSW |
8 |
62,470,783 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0403:Ddx60
|
UTSW |
8 |
62,447,575 (GRCm39) |
splice site |
probably benign |
|
|
R0479:Ddx60
|
UTSW |
8 |
62,422,691 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0561:Ddx60
|
UTSW |
8 |
62,470,828 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0844:Ddx60
|
UTSW |
8 |
62,440,395 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1119:Ddx60
|
UTSW |
8 |
62,395,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1428:Ddx60
|
UTSW |
8 |
62,411,193 (GRCm39) |
splice site |
probably benign |
|
|
R1778:Ddx60
|
UTSW |
8 |
62,427,210 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R1840:Ddx60
|
UTSW |
8 |
62,422,587 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1970:Ddx60
|
UTSW |
8 |
62,425,240 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R2101:Ddx60
|
UTSW |
8 |
62,393,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2174:Ddx60
|
UTSW |
8 |
62,470,234 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2174:Ddx60
|
UTSW |
8 |
62,409,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2198:Ddx60
|
UTSW |
8 |
62,411,097 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2332:Ddx60
|
UTSW |
8 |
62,490,125 (GRCm39) |
missense |
probably benign |
0.08 |
|
R2338:Ddx60
|
UTSW |
8 |
62,465,470 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R2379:Ddx60
|
UTSW |
8 |
62,490,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4010:Ddx60
|
UTSW |
8 |
62,409,178 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4010:Ddx60
|
UTSW |
8 |
62,407,569 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R4133:Ddx60
|
UTSW |
8 |
62,425,254 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4282:Ddx60
|
UTSW |
8 |
62,447,427 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4382:Ddx60
|
UTSW |
8 |
62,402,012 (GRCm39) |
splice site |
probably null |
|
|
R4561:Ddx60
|
UTSW |
8 |
62,395,495 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4572:Ddx60
|
UTSW |
8 |
62,440,455 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4581:Ddx60
|
UTSW |
8 |
62,476,295 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4635:Ddx60
|
UTSW |
8 |
62,490,101 (GRCm39) |
missense |
probably benign |
0.28 |
|
R4698:Ddx60
|
UTSW |
8 |
62,465,458 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4807:Ddx60
|
UTSW |
8 |
62,432,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4858:Ddx60
|
UTSW |
8 |
62,474,348 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4964:Ddx60
|
UTSW |
8 |
62,432,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5120:Ddx60
|
UTSW |
8 |
62,398,940 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5187:Ddx60
|
UTSW |
8 |
62,427,222 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5222:Ddx60
|
UTSW |
8 |
62,437,192 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5400:Ddx60
|
UTSW |
8 |
62,463,036 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R5500:Ddx60
|
UTSW |
8 |
62,403,485 (GRCm39) |
missense |
probably benign |
0.28 |
|
R5514:Ddx60
|
UTSW |
8 |
62,411,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5668:Ddx60
|
UTSW |
8 |
62,453,612 (GRCm39) |
missense |
probably benign |
0.38 |
|
R5742:Ddx60
|
UTSW |
8 |
62,401,955 (GRCm39) |
missense |
probably benign |
|
|
R5772:Ddx60
|
UTSW |
8 |
62,401,931 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5810:Ddx60
|
UTSW |
8 |
62,465,422 (GRCm39) |
nonsense |
probably null |
|
|
R5815:Ddx60
|
UTSW |
8 |
62,416,756 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5820:Ddx60
|
UTSW |
8 |
62,409,155 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5866:Ddx60
|
UTSW |
8 |
62,393,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5881:Ddx60
|
UTSW |
8 |
62,490,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5977:Ddx60
|
UTSW |
8 |
62,474,444 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6048:Ddx60
|
UTSW |
8 |
62,453,616 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6061:Ddx60
|
UTSW |
8 |
62,476,275 (GRCm39) |
missense |
probably null |
0.01 |
|
R6153:Ddx60
|
UTSW |
8 |
62,398,974 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R6287:Ddx60
|
UTSW |
8 |
62,403,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6415:Ddx60
|
UTSW |
8 |
62,436,939 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6416:Ddx60
|
UTSW |
8 |
62,451,715 (GRCm39) |
missense |
probably benign |
|
|
R6416:Ddx60
|
UTSW |
8 |
62,430,984 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6660:Ddx60
|
UTSW |
8 |
62,409,273 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6694:Ddx60
|
UTSW |
8 |
62,490,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6715:Ddx60
|
UTSW |
8 |
62,436,924 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6720:Ddx60
|
UTSW |
8 |
62,453,723 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6937:Ddx60
|
UTSW |
8 |
62,490,103 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7153:Ddx60
|
UTSW |
8 |
62,441,142 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7274:Ddx60
|
UTSW |
8 |
62,393,142 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7409:Ddx60
|
UTSW |
8 |
62,411,612 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7464:Ddx60
|
UTSW |
8 |
62,393,708 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7670:Ddx60
|
UTSW |
8 |
62,428,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7904:Ddx60
|
UTSW |
8 |
62,430,924 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7992:Ddx60
|
UTSW |
8 |
62,407,569 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8124:Ddx60
|
UTSW |
8 |
62,436,945 (GRCm39) |
missense |
probably benign |
|
|
R8125:Ddx60
|
UTSW |
8 |
62,436,945 (GRCm39) |
missense |
probably benign |
|
|
R8126:Ddx60
|
UTSW |
8 |
62,436,945 (GRCm39) |
missense |
probably benign |
|
|
R8155:Ddx60
|
UTSW |
8 |
62,470,205 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R8174:Ddx60
|
UTSW |
8 |
62,470,284 (GRCm39) |
splice site |
probably null |
|
|
R8192:Ddx60
|
UTSW |
8 |
62,431,002 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8271:Ddx60
|
UTSW |
8 |
62,393,142 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8301:Ddx60
|
UTSW |
8 |
62,453,631 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8304:Ddx60
|
UTSW |
8 |
62,451,803 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8319:Ddx60
|
UTSW |
8 |
62,395,669 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8374:Ddx60
|
UTSW |
8 |
62,427,205 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8401:Ddx60
|
UTSW |
8 |
62,409,277 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R8487:Ddx60
|
UTSW |
8 |
62,427,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8804:Ddx60
|
UTSW |
8 |
62,411,640 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8826:Ddx60
|
UTSW |
8 |
62,398,990 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8829:Ddx60
|
UTSW |
8 |
62,393,695 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8881:Ddx60
|
UTSW |
8 |
62,474,343 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8884:Ddx60
|
UTSW |
8 |
62,447,553 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8990:Ddx60
|
UTSW |
8 |
62,427,168 (GRCm39) |
nonsense |
probably null |
|
|
R9122:Ddx60
|
UTSW |
8 |
62,442,898 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9225:Ddx60
|
UTSW |
8 |
62,470,875 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9278:Ddx60
|
UTSW |
8 |
62,431,012 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9293:Ddx60
|
UTSW |
8 |
62,462,994 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9405:Ddx60
|
UTSW |
8 |
62,425,248 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9766:Ddx60
|
UTSW |
8 |
62,465,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0003:Ddx60
|
UTSW |
8 |
62,486,451 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
X0019:Ddx60
|
UTSW |
8 |
62,416,726 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1177:Ddx60
|
UTSW |
8 |
62,453,622 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGGAGTGGCATACCTTAATTTC -3'
(R):5'- GAATCCTGCTGTAACAACCTTTATCC -3'
Sequencing Primer
(F):5'- CCCTTGCAGTTGTTATATTACTGAAG -3'
(R):5'- CCCATTGTAACAATCTGTATTCCAG -3'
|
| Posted On |
2014-08-01 |
Incidental Mutation