Incidental Mutation 'R4646:Dock9'
| ID |
350282 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dock9
|
| Ensembl Gene |
ENSMUSG00000025558 |
| Gene Name |
dedicator of cytokinesis 9 |
| Synonyms |
D14Wsu89e, B230309H04Rik, Zizimin1 |
| MMRRC Submission |
041907-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4646 (G1)
|
| Quality Score |
211 |
|
Status
|
Not validated
|
| Chromosome |
14 |
| Chromosomal Location |
121779458-122035249 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 121823658 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Histidine
at position 1428
(L1428H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000148834
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000040700]
[ENSMUST00000100299]
[ENSMUST00000212181]
[ENSMUST00000212376]
[ENSMUST00000212416]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000040700
AA Change: L1427H
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000047881
Gene: ENSMUSG00000025558
AA Change: L1427H
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3398
|
58 |
151 |
5.6e-36 |
PFAM |
|
PH
|
172 |
280 |
1.38e-16 |
SMART |
|
Blast:PH
|
297 |
372 |
4e-25 |
BLAST |
|
Pfam:DOCK-C2
|
631 |
822 |
5.3e-51 |
PFAM |
|
Pfam:DHR-2
|
1523 |
2068 |
2.1e-212 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000100299
AA Change: L1398H
PolyPhen 2
Score 0.994 (Sensitivity: 0.69; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000097872
Gene: ENSMUSG00000025558
AA Change: L1398H
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3398
|
58 |
153 |
1.5e-32 |
PFAM |
|
PH
|
174 |
282 |
1.38e-16 |
SMART |
|
Blast:PH
|
299 |
374 |
4e-25 |
BLAST |
|
Pfam:DOCK-C2
|
632 |
825 |
1.3e-59 |
PFAM |
|
low complexity region
|
1752 |
1763 |
N/A |
INTRINSIC |
|
Pfam:Ded_cyto
|
1836 |
2013 |
2.4e-69 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000211803
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000211907
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000212181
AA Change: L1428H
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| Predicted Effect |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000212371
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000212376
AA Change: L1418H
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000212719
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000212416
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.6%
- 10x: 97.4%
- 20x: 95.6%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700031F05Rik |
G |
T |
X: 101,904,515 (GRCm39) |
N132K |
possibly damaging |
Het |
| 2010315B03Rik |
T |
A |
9: 124,056,228 (GRCm39) |
Y232F |
probably benign |
Het |
| Acadl |
A |
T |
1: 66,870,602 (GRCm39) |
S428R |
probably benign |
Het |
| Adamts10 |
A |
G |
17: 33,764,529 (GRCm39) |
D683G |
probably damaging |
Het |
| Angptl4 |
G |
A |
17: 34,000,273 (GRCm39) |
P32S |
probably benign |
Het |
| Apob |
A |
G |
12: 8,062,759 (GRCm39) |
N134S |
probably benign |
Het |
| Atr |
G |
A |
9: 95,753,250 (GRCm39) |
|
probably null |
Het |
| B4galnt1 |
G |
A |
10: 127,003,705 (GRCm39) |
V223M |
probably damaging |
Het |
| Bbs10 |
A |
G |
10: 111,136,995 (GRCm39) |
K703E |
probably benign |
Het |
| C1galt1c1 |
A |
T |
X: 37,720,349 (GRCm39) |
S216T |
probably benign |
Het |
| C2cd3 |
A |
C |
7: 100,021,657 (GRCm39) |
|
probably benign |
Het |
| Clca4b |
A |
C |
3: 144,634,286 (GRCm39) |
H102Q |
probably benign |
Het |
| Cntrl |
T |
C |
2: 35,039,473 (GRCm39) |
I557T |
probably damaging |
Het |
| Col26a1 |
G |
A |
5: 136,876,404 (GRCm39) |
S72F |
probably damaging |
Het |
| Crocc2 |
G |
A |
1: 93,096,516 (GRCm39) |
V24M |
possibly damaging |
Het |
| Csmd1 |
T |
C |
8: 15,982,511 (GRCm39) |
I2719V |
possibly damaging |
Het |
| Cul9 |
C |
T |
17: 46,849,943 (GRCm39) |
W502* |
probably null |
Het |
| Dazl |
A |
T |
17: 50,595,183 (GRCm39) |
F84I |
probably damaging |
Het |
| Dcaf1 |
G |
T |
9: 106,724,006 (GRCm39) |
R478L |
probably benign |
Het |
| Dock5 |
T |
G |
14: 68,080,228 (GRCm39) |
I198L |
probably benign |
Het |
| Dync1li1 |
T |
A |
9: 114,538,237 (GRCm39) |
V198E |
probably damaging |
Het |
| Egf |
A |
T |
3: 129,513,925 (GRCm39) |
C429S |
probably damaging |
Het |
| Ehmt1 |
T |
C |
2: 24,781,696 (GRCm39) |
E7G |
probably null |
Het |
| Ercc4 |
G |
T |
16: 12,965,438 (GRCm39) |
R690L |
probably damaging |
Het |
| Erich5 |
T |
C |
15: 34,471,112 (GRCm39) |
C114R |
possibly damaging |
Het |
| Etv1 |
T |
C |
12: 38,915,685 (GRCm39) |
S428P |
possibly damaging |
Het |
| Fbxo31 |
G |
T |
8: 122,286,755 (GRCm39) |
F174L |
probably benign |
Het |
| Fbxo33 |
T |
A |
12: 59,251,217 (GRCm39) |
I433L |
probably benign |
Het |
| Fez2 |
A |
T |
17: 78,720,357 (GRCm39) |
V99E |
probably damaging |
Het |
| Gabarapl2 |
A |
C |
8: 112,669,185 (GRCm39) |
K48Q |
probably damaging |
Het |
| Gfi1b |
T |
A |
2: 28,500,149 (GRCm39) |
H294L |
probably damaging |
Het |
| Gk2 |
A |
G |
5: 97,604,056 (GRCm39) |
S261P |
probably damaging |
Het |
| Gpr158 |
T |
C |
2: 21,831,864 (GRCm39) |
I988T |
probably benign |
Het |
| Grk3 |
G |
C |
5: 113,077,586 (GRCm39) |
H394D |
probably benign |
Het |
| Grm6 |
A |
G |
11: 50,748,033 (GRCm39) |
E381G |
probably benign |
Het |
| Gtf3c1 |
A |
T |
7: 125,258,266 (GRCm39) |
M1268K |
possibly damaging |
Het |
| Hikeshi |
A |
T |
7: 89,572,854 (GRCm39) |
I113N |
probably damaging |
Het |
| Hmg20b |
T |
A |
10: 81,184,416 (GRCm39) |
Q129L |
probably damaging |
Het |
| Hunk |
C |
A |
16: 90,272,791 (GRCm39) |
T365K |
probably damaging |
Het |
| Ints15 |
A |
T |
5: 143,293,740 (GRCm39) |
W246R |
probably damaging |
Het |
| Kdm5a |
T |
G |
6: 120,351,938 (GRCm39) |
V176G |
possibly damaging |
Het |
| Kif2a |
T |
A |
13: 107,098,693 (GRCm39) |
E691V |
probably damaging |
Het |
| Ly6e |
T |
C |
15: 74,830,510 (GRCm39) |
|
probably null |
Het |
| Map1b |
G |
T |
13: 99,568,977 (GRCm39) |
P1248Q |
unknown |
Het |
| Mettl25 |
A |
G |
10: 105,662,416 (GRCm39) |
S185P |
probably damaging |
Het |
| Mfap3l |
T |
A |
8: 61,124,184 (GRCm39) |
V142D |
probably damaging |
Het |
| Mip |
T |
A |
10: 128,062,922 (GRCm39) |
H122Q |
probably benign |
Het |
| Mkx |
G |
A |
18: 6,992,040 (GRCm39) |
T280I |
probably benign |
Het |
| Msi1 |
A |
T |
5: 115,589,514 (GRCm39) |
|
probably null |
Het |
| Mtcl2 |
T |
C |
2: 156,862,426 (GRCm39) |
E1501G |
probably damaging |
Het |
| Muc5b |
A |
G |
7: 141,416,377 (GRCm39) |
M3108V |
probably benign |
Het |
| Mybl1 |
A |
G |
1: 9,742,511 (GRCm39) |
S625P |
probably damaging |
Het |
| Myo7b |
C |
A |
18: 32,127,422 (GRCm39) |
V627F |
probably benign |
Het |
| Ndst3 |
A |
T |
3: 123,465,684 (GRCm39) |
I96N |
probably damaging |
Het |
| Nrp1 |
A |
T |
8: 129,184,425 (GRCm39) |
T357S |
probably benign |
Het |
| Obscn |
G |
T |
11: 59,015,396 (GRCm39) |
Y1050* |
probably null |
Het |
| Or2ak7 |
A |
G |
11: 58,575,556 (GRCm39) |
N286D |
probably damaging |
Het |
| Or2d4 |
A |
T |
7: 106,543,547 (GRCm39) |
N220K |
probably benign |
Het |
| Or2y1c |
A |
C |
11: 49,361,451 (GRCm39) |
I158L |
probably benign |
Het |
| Or4c107 |
T |
A |
2: 88,789,556 (GRCm39) |
F249I |
probably damaging |
Het |
| Or5d47 |
A |
T |
2: 87,804,142 (GRCm39) |
I289K |
probably benign |
Het |
| Or5i1 |
T |
C |
2: 87,613,565 (GRCm39) |
V227A |
possibly damaging |
Het |
| Otof |
T |
C |
5: 30,540,914 (GRCm39) |
E875G |
possibly damaging |
Het |
| Pick1 |
A |
T |
15: 79,133,137 (GRCm39) |
D399V |
probably benign |
Het |
| Pik3c2g |
T |
A |
6: 139,665,744 (GRCm39) |
S22T |
probably benign |
Het |
| Pnpla2 |
A |
G |
7: 141,038,574 (GRCm39) |
E276G |
possibly damaging |
Het |
| Pomk |
A |
T |
8: 26,473,633 (GRCm39) |
S107T |
probably damaging |
Het |
| Rbm46 |
A |
T |
3: 82,771,765 (GRCm39) |
D283E |
probably benign |
Het |
| Rimbp3 |
A |
G |
16: 17,030,962 (GRCm39) |
D1462G |
probably damaging |
Het |
| Rnf112 |
T |
A |
11: 61,342,936 (GRCm39) |
E230V |
probably damaging |
Het |
| Rock1 |
T |
C |
18: 10,112,391 (GRCm39) |
T455A |
probably benign |
Het |
| Rtp4 |
A |
T |
16: 23,428,790 (GRCm39) |
M18L |
probably benign |
Het |
| Scaf11 |
A |
T |
15: 96,317,981 (GRCm39) |
|
probably null |
Het |
| Schip1 |
T |
C |
3: 67,972,297 (GRCm39) |
V8A |
probably benign |
Het |
| Sec31b |
T |
C |
19: 44,515,060 (GRCm39) |
H351R |
probably benign |
Het |
| Sh3bp5l |
A |
G |
11: 58,237,177 (GRCm39) |
D378G |
probably benign |
Het |
| Sowahb |
T |
C |
5: 93,190,715 (GRCm39) |
D668G |
probably damaging |
Het |
| Spam1 |
A |
G |
6: 24,800,586 (GRCm39) |
T442A |
probably benign |
Het |
| Syt14 |
T |
A |
1: 192,615,633 (GRCm39) |
Y451F |
probably damaging |
Het |
| Tafa5 |
T |
G |
15: 87,604,783 (GRCm39) |
S115A |
probably damaging |
Het |
| Tdh |
A |
G |
14: 63,731,205 (GRCm39) |
L323P |
possibly damaging |
Het |
| Tet2 |
A |
T |
3: 133,193,843 (GRCm39) |
M197K |
probably benign |
Het |
| Thbs1 |
G |
A |
2: 117,948,810 (GRCm39) |
A489T |
probably benign |
Het |
| Tnfaip1 |
C |
T |
11: 78,420,008 (GRCm39) |
R88Q |
probably damaging |
Het |
| Tnn |
T |
C |
1: 159,973,612 (GRCm39) |
M252V |
probably benign |
Het |
| Trdn |
G |
T |
10: 33,071,977 (GRCm39) |
E215* |
probably null |
Het |
| Trim55 |
T |
C |
3: 19,725,286 (GRCm39) |
F268L |
probably benign |
Het |
| Trmt112 |
T |
A |
19: 6,887,816 (GRCm39) |
V55E |
possibly damaging |
Het |
| Tube1 |
A |
G |
10: 39,018,363 (GRCm39) |
M147V |
possibly damaging |
Het |
| Ubn1 |
A |
G |
16: 4,895,851 (GRCm39) |
T966A |
probably damaging |
Het |
| Unc80 |
A |
G |
1: 66,708,394 (GRCm39) |
I2651V |
probably benign |
Het |
| Vmn1r172 |
G |
A |
7: 23,359,919 (GRCm39) |
R268H |
probably benign |
Het |
| Vmn1r231 |
T |
A |
17: 21,110,571 (GRCm39) |
I115F |
probably damaging |
Het |
| Vmn1r237 |
A |
G |
17: 21,534,400 (GRCm39) |
K41R |
probably benign |
Het |
| Vmn2r58 |
A |
T |
7: 41,509,935 (GRCm39) |
N547K |
probably damaging |
Het |
| Vmn2r74 |
T |
C |
7: 85,606,782 (GRCm39) |
D188G |
probably benign |
Het |
| Vwa5b2 |
A |
G |
16: 20,415,079 (GRCm39) |
K367R |
probably damaging |
Het |
| Washc4 |
T |
A |
10: 83,410,407 (GRCm39) |
M665K |
possibly damaging |
Het |
| Wbp11 |
T |
A |
6: 136,798,189 (GRCm39) |
Y236F |
probably benign |
Het |
| Wbp4 |
T |
A |
14: 79,709,801 (GRCm39) |
I145F |
possibly damaging |
Het |
| Wwc2 |
C |
A |
8: 48,373,636 (GRCm39) |
D77Y |
probably damaging |
Het |
| Zpld2 |
G |
A |
4: 133,929,459 (GRCm39) |
A282V |
probably benign |
Het |
|
| Other mutations in Dock9 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00236:Dock9
|
APN |
14 |
121,905,880 (GRCm39) |
missense |
probably benign |
0.12 |
|
IGL00817:Dock9
|
APN |
14 |
121,935,703 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL00923:Dock9
|
APN |
14 |
121,844,504 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01385:Dock9
|
APN |
14 |
121,817,995 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01567:Dock9
|
APN |
14 |
121,890,496 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01767:Dock9
|
APN |
14 |
121,860,282 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01811:Dock9
|
APN |
14 |
121,796,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02512:Dock9
|
APN |
14 |
121,856,950 (GRCm39) |
splice site |
probably benign |
|
|
IGL02525:Dock9
|
APN |
14 |
121,877,538 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02550:Dock9
|
APN |
14 |
121,935,724 (GRCm39) |
start codon destroyed |
probably null |
0.07 |
|
IGL02559:Dock9
|
APN |
14 |
121,862,559 (GRCm39) |
splice site |
probably benign |
|
|
IGL02666:Dock9
|
APN |
14 |
121,818,111 (GRCm39) |
missense |
probably benign |
0.42 |
|
IGL02674:Dock9
|
APN |
14 |
121,833,023 (GRCm39) |
splice site |
probably null |
|
|
IGL02795:Dock9
|
APN |
14 |
121,877,390 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL03074:Dock9
|
APN |
14 |
121,844,682 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03095:Dock9
|
APN |
14 |
121,876,940 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03294:Dock9
|
APN |
14 |
121,879,035 (GRCm39) |
splice site |
probably benign |
|
|
R0036:Dock9
|
UTSW |
14 |
121,860,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0050:Dock9
|
UTSW |
14 |
121,844,637 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0050:Dock9
|
UTSW |
14 |
121,844,637 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0164:Dock9
|
UTSW |
14 |
121,835,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0164:Dock9
|
UTSW |
14 |
121,835,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0270:Dock9
|
UTSW |
14 |
121,813,411 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0494:Dock9
|
UTSW |
14 |
121,899,996 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R0726:Dock9
|
UTSW |
14 |
121,889,180 (GRCm39) |
nonsense |
probably null |
|
|
R1029:Dock9
|
UTSW |
14 |
121,837,096 (GRCm39) |
splice site |
probably null |
|
|
R1214:Dock9
|
UTSW |
14 |
121,823,728 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1231:Dock9
|
UTSW |
14 |
121,813,362 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1535:Dock9
|
UTSW |
14 |
121,783,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1629:Dock9
|
UTSW |
14 |
121,780,986 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1637:Dock9
|
UTSW |
14 |
121,889,187 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1733:Dock9
|
UTSW |
14 |
121,864,292 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1772:Dock9
|
UTSW |
14 |
121,847,210 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1855:Dock9
|
UTSW |
14 |
121,877,571 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1888:Dock9
|
UTSW |
14 |
121,862,617 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1888:Dock9
|
UTSW |
14 |
121,862,617 (GRCm39) |
missense |
probably benign |
0.18 |
|
R1901:Dock9
|
UTSW |
14 |
121,862,565 (GRCm39) |
splice site |
probably null |
|
|
R1920:Dock9
|
UTSW |
14 |
121,820,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1987:Dock9
|
UTSW |
14 |
121,829,242 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3035:Dock9
|
UTSW |
14 |
121,844,249 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R3851:Dock9
|
UTSW |
14 |
121,866,498 (GRCm39) |
splice site |
probably null |
|
|
R4020:Dock9
|
UTSW |
14 |
121,844,267 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4021:Dock9
|
UTSW |
14 |
121,864,324 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4089:Dock9
|
UTSW |
14 |
121,820,883 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4258:Dock9
|
UTSW |
14 |
121,818,854 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4423:Dock9
|
UTSW |
14 |
121,799,465 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4561:Dock9
|
UTSW |
14 |
121,796,419 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4604:Dock9
|
UTSW |
14 |
121,905,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4647:Dock9
|
UTSW |
14 |
121,823,658 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4776:Dock9
|
UTSW |
14 |
121,847,509 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4809:Dock9
|
UTSW |
14 |
121,784,008 (GRCm39) |
missense |
probably benign |
0.37 |
|
R4865:Dock9
|
UTSW |
14 |
121,780,917 (GRCm39) |
makesense |
probably null |
|
|
R4951:Dock9
|
UTSW |
14 |
121,890,547 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5151:Dock9
|
UTSW |
14 |
121,815,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5359:Dock9
|
UTSW |
14 |
121,890,472 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5366:Dock9
|
UTSW |
14 |
121,815,615 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5502:Dock9
|
UTSW |
14 |
121,847,594 (GRCm39) |
splice site |
probably null |
|
|
R5579:Dock9
|
UTSW |
14 |
121,837,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5753:Dock9
|
UTSW |
14 |
121,872,037 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5836:Dock9
|
UTSW |
14 |
121,918,763 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5858:Dock9
|
UTSW |
14 |
121,866,204 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5890:Dock9
|
UTSW |
14 |
121,905,820 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6075:Dock9
|
UTSW |
14 |
121,783,385 (GRCm39) |
missense |
probably benign |
|
|
R6298:Dock9
|
UTSW |
14 |
121,872,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6306:Dock9
|
UTSW |
14 |
121,799,492 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6321:Dock9
|
UTSW |
14 |
121,783,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6330:Dock9
|
UTSW |
14 |
121,842,655 (GRCm39) |
start codon destroyed |
probably null |
0.00 |
|
R6719:Dock9
|
UTSW |
14 |
121,847,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6784:Dock9
|
UTSW |
14 |
121,780,926 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6826:Dock9
|
UTSW |
14 |
121,860,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6830:Dock9
|
UTSW |
14 |
121,860,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6838:Dock9
|
UTSW |
14 |
121,784,008 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6868:Dock9
|
UTSW |
14 |
121,823,676 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6919:Dock9
|
UTSW |
14 |
121,880,564 (GRCm39) |
missense |
probably benign |
0.42 |
|
R6989:Dock9
|
UTSW |
14 |
121,864,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7539:Dock9
|
UTSW |
14 |
121,818,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7645:Dock9
|
UTSW |
14 |
121,835,075 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7875:Dock9
|
UTSW |
14 |
121,863,396 (GRCm39) |
nonsense |
probably null |
|
|
R7900:Dock9
|
UTSW |
14 |
121,783,491 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R8040:Dock9
|
UTSW |
14 |
121,889,206 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8420:Dock9
|
UTSW |
14 |
121,783,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8511:Dock9
|
UTSW |
14 |
121,918,847 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8511:Dock9
|
UTSW |
14 |
121,864,801 (GRCm39) |
missense |
probably benign |
0.40 |
|
R8514:Dock9
|
UTSW |
14 |
121,896,199 (GRCm39) |
missense |
probably benign |
0.25 |
|
R8691:Dock9
|
UTSW |
14 |
121,877,517 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R8804:Dock9
|
UTSW |
14 |
121,842,595 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8894:Dock9
|
UTSW |
14 |
121,860,373 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8900:Dock9
|
UTSW |
14 |
121,817,940 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9069:Dock9
|
UTSW |
14 |
121,866,324 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9218:Dock9
|
UTSW |
14 |
121,905,871 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9233:Dock9
|
UTSW |
14 |
121,820,781 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9236:Dock9
|
UTSW |
14 |
121,876,970 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9285:Dock9
|
UTSW |
14 |
121,833,012 (GRCm39) |
missense |
probably benign |
|
|
R9451:Dock9
|
UTSW |
14 |
121,787,601 (GRCm39) |
splice site |
probably benign |
|
|
R9461:Dock9
|
UTSW |
14 |
121,842,601 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9484:Dock9
|
UTSW |
14 |
121,818,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9517:Dock9
|
UTSW |
14 |
121,829,236 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9542:Dock9
|
UTSW |
14 |
121,864,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9694:Dock9
|
UTSW |
14 |
121,818,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9701:Dock9
|
UTSW |
14 |
121,876,983 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9703:Dock9
|
UTSW |
14 |
121,781,989 (GRCm39) |
makesense |
probably null |
|
|
R9726:Dock9
|
UTSW |
14 |
121,835,149 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R9741:Dock9
|
UTSW |
14 |
121,877,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Dock9
|
UTSW |
14 |
121,792,687 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dock9
|
UTSW |
14 |
121,889,194 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCTTTCTTACACTCACGACGG -3'
(R):5'- AAGTTGACTGTTACTGCCGCAC -3'
Sequencing Primer
(F):5'- TTCTTACACTCACGACGGGAATG -3'
(R):5'- GTTACTGCCGCACCCCAC -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation