Incidental Mutation 'R0281:Cfap65'
| ID |
37485 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cfap65
|
| Ensembl Gene |
ENSMUSG00000047021 |
| Gene Name |
cilia and flagella associated protein 65 |
| Synonyms |
Ccdc108, B230363K08Rik |
| MMRRC Submission |
038503-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.677)
|
| Stock # |
R0281 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
74941230-74974758 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 74966230 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 366
(I366F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000092440
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000094844]
|
| AlphaFold |
Q3V0B4 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000094844
AA Change: I366F
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000092440
Gene: ENSMUSG00000047021
AA Change: I366F
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
111 |
133 |
N/A |
INTRINSIC |
|
low complexity region
|
212 |
223 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
745 |
890 |
9.31e-5 |
PROSPERO |
|
internal_repeat_1
|
1167 |
1322 |
9.31e-5 |
PROSPERO |
|
low complexity region
|
1350 |
1361 |
N/A |
INTRINSIC |
|
low complexity region
|
1574 |
1592 |
N/A |
INTRINSIC |
|
coiled coil region
|
1687 |
1724 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000130489
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139950
|
| Meta Mutation Damage Score |
0.2624 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 93.9%
|
| Validation Efficiency |
98% (104/106) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene has putative coiled-coil domains and may be a transmembrane protein. The chicken ortholog of this gene is involved in the Rose-comb mutation, which is a large chromosome inversion, resulting in altered comb morphology and defects in sperm motility. [provided by RefSeq, Aug 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 101 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933430I17Rik |
A |
T |
4: 62,464,304 (GRCm39) |
R374* |
probably null |
Het |
| 5930422O12Rik |
A |
T |
8: 33,919,407 (GRCm39) |
R76* |
probably null |
Het |
| A1cf |
G |
A |
19: 31,923,214 (GRCm39) |
A505T |
probably benign |
Het |
| Abcc5 |
T |
A |
16: 20,241,150 (GRCm39) |
I12F |
probably damaging |
Het |
| Abcf2 |
T |
C |
5: 24,771,562 (GRCm39) |
E555G |
probably damaging |
Het |
| Acan |
A |
T |
7: 78,750,033 (GRCm39) |
E1601D |
probably damaging |
Het |
| Acsbg3 |
T |
A |
17: 57,192,169 (GRCm39) |
Y577* |
probably null |
Het |
| Adam2 |
T |
A |
14: 66,275,055 (GRCm39) |
K559N |
probably benign |
Het |
| Akap11 |
A |
C |
14: 78,747,529 (GRCm39) |
D1619E |
possibly damaging |
Het |
| Ankrd11 |
T |
C |
8: 123,622,307 (GRCm39) |
D515G |
probably benign |
Het |
| Ankrd27 |
T |
A |
7: 35,318,796 (GRCm39) |
N562K |
probably damaging |
Het |
| Atp10b |
T |
C |
11: 43,044,131 (GRCm39) |
I119T |
probably benign |
Het |
| Atr |
T |
C |
9: 95,819,619 (GRCm39) |
I2202T |
probably benign |
Het |
| Bltp2 |
C |
T |
11: 78,162,750 (GRCm39) |
L871F |
possibly damaging |
Het |
| Brd4 |
T |
A |
17: 32,432,514 (GRCm39) |
|
probably benign |
Het |
| Catsperg2 |
C |
T |
7: 29,405,996 (GRCm39) |
C634Y |
possibly damaging |
Het |
| Cep192 |
A |
G |
18: 67,961,553 (GRCm39) |
|
probably benign |
Het |
| Cnga4 |
G |
T |
7: 105,056,875 (GRCm39) |
R326L |
probably damaging |
Het |
| Cntnap5b |
T |
A |
1: 99,999,878 (GRCm39) |
M212K |
probably benign |
Het |
| Col6a6 |
T |
A |
9: 105,661,315 (GRCm39) |
M265L |
probably benign |
Het |
| Cspg4b |
A |
T |
13: 113,505,677 (GRCm39) |
I727F |
probably damaging |
Het |
| Cyp26b1 |
A |
T |
6: 84,551,538 (GRCm39) |
F417Y |
probably damaging |
Het |
| Dhx15 |
A |
T |
5: 52,308,088 (GRCm39) |
M768K |
probably benign |
Het |
| Drc7 |
G |
A |
8: 95,797,881 (GRCm39) |
R433H |
possibly damaging |
Het |
| Duox2 |
C |
T |
2: 122,122,785 (GRCm39) |
V550M |
probably benign |
Het |
| Elmo2 |
A |
G |
2: 165,138,810 (GRCm39) |
L456P |
probably damaging |
Het |
| Fbxo39 |
T |
C |
11: 72,208,356 (GRCm39) |
I236T |
probably benign |
Het |
| Fezf2 |
A |
G |
14: 12,343,977 (GRCm38) |
C305R |
probably damaging |
Het |
| Fndc3b |
C |
A |
3: 27,511,155 (GRCm39) |
C785F |
probably benign |
Het |
| Gm12253 |
T |
C |
11: 58,330,838 (GRCm39) |
|
probably benign |
Het |
| Gnat2 |
T |
A |
3: 108,002,878 (GRCm39) |
Y95* |
probably null |
Het |
| Gopc |
T |
C |
10: 52,226,774 (GRCm39) |
K220E |
probably damaging |
Het |
| Hectd4 |
G |
A |
5: 121,392,314 (GRCm39) |
D193N |
possibly damaging |
Het |
| Hexa |
G |
A |
9: 59,461,509 (GRCm39) |
|
probably null |
Het |
| Hspa4l |
T |
C |
3: 40,739,840 (GRCm39) |
|
probably benign |
Het |
| Hspa5 |
T |
C |
2: 34,664,332 (GRCm39) |
S301P |
probably damaging |
Het |
| Ice1 |
A |
T |
13: 70,752,166 (GRCm39) |
S1307T |
possibly damaging |
Het |
| Igtp |
T |
C |
11: 58,096,880 (GRCm39) |
L17P |
probably damaging |
Het |
| Itk |
T |
C |
11: 46,244,743 (GRCm39) |
Y225C |
probably damaging |
Het |
| Kifc3 |
A |
G |
8: 95,830,088 (GRCm39) |
V560A |
probably damaging |
Het |
| Lama1 |
A |
G |
17: 68,124,564 (GRCm39) |
N2875D |
probably damaging |
Het |
| Lasp1 |
C |
A |
11: 97,697,677 (GRCm39) |
C32* |
probably null |
Het |
| Lcp2 |
T |
A |
11: 34,019,854 (GRCm39) |
|
probably benign |
Het |
| Lhx9 |
C |
T |
1: 138,760,642 (GRCm39) |
G236D |
probably benign |
Het |
| Lrrc38 |
A |
T |
4: 143,076,979 (GRCm39) |
I81F |
probably damaging |
Het |
| Ly6a |
C |
T |
15: 74,867,236 (GRCm39) |
V94M |
probably benign |
Het |
| Map3k13 |
A |
G |
16: 21,732,907 (GRCm39) |
E503G |
probably damaging |
Het |
| Mertk |
T |
C |
2: 128,624,541 (GRCm39) |
|
probably benign |
Het |
| Mrtfb |
T |
A |
16: 13,230,027 (GRCm39) |
I915N |
probably damaging |
Het |
| Msantd2 |
G |
A |
9: 37,434,515 (GRCm39) |
D252N |
possibly damaging |
Het |
| Mtmr12 |
T |
A |
15: 12,257,792 (GRCm39) |
L290* |
probably null |
Het |
| Myo3a |
T |
C |
2: 22,250,409 (GRCm39) |
I92T |
probably benign |
Het |
| Naglu |
T |
A |
11: 100,964,853 (GRCm39) |
N313K |
probably damaging |
Het |
| Nceh1 |
T |
C |
3: 27,276,953 (GRCm39) |
V92A |
possibly damaging |
Het |
| Ncf4 |
A |
G |
15: 78,135,083 (GRCm39) |
T47A |
probably damaging |
Het |
| Nrp1 |
T |
A |
8: 129,187,164 (GRCm39) |
F403L |
probably damaging |
Het |
| Nxph3 |
T |
C |
11: 95,402,082 (GRCm39) |
T111A |
possibly damaging |
Het |
| Obscn |
T |
A |
11: 58,929,441 (GRCm39) |
E6061V |
probably damaging |
Het |
| Obsl1 |
C |
A |
1: 75,469,571 (GRCm39) |
G1149W |
probably damaging |
Het |
| Or14c39 |
A |
G |
7: 86,344,068 (GRCm39) |
T135A |
probably benign |
Het |
| Or2k2 |
A |
T |
4: 58,784,981 (GRCm39) |
V247E |
probably damaging |
Het |
| Or2p2 |
T |
A |
13: 21,256,544 (GRCm39) |
Y309F |
probably benign |
Het |
| Or5b123 |
A |
G |
19: 13,596,849 (GRCm39) |
T65A |
probably benign |
Het |
| Or5d14 |
C |
T |
2: 87,880,756 (GRCm39) |
V71I |
possibly damaging |
Het |
| Or5p68 |
A |
C |
7: 107,946,121 (GRCm39) |
D22E |
probably benign |
Het |
| Or6c70 |
T |
A |
10: 129,710,415 (GRCm39) |
L70F |
possibly damaging |
Het |
| Pde9a |
T |
C |
17: 31,674,080 (GRCm39) |
V55A |
probably damaging |
Het |
| Pip4k2c |
A |
T |
10: 127,041,690 (GRCm39) |
|
probably null |
Het |
| Plvap |
T |
C |
8: 71,964,026 (GRCm39) |
N112S |
probably damaging |
Het |
| Pop1 |
T |
A |
15: 34,530,004 (GRCm39) |
|
probably null |
Het |
| Ppip5k2 |
T |
C |
1: 97,644,278 (GRCm39) |
H1113R |
possibly damaging |
Het |
| Ptprk |
A |
T |
10: 28,449,388 (GRCm39) |
I962F |
probably damaging |
Het |
| Rad51ap2 |
T |
C |
12: 11,507,043 (GRCm39) |
S322P |
possibly damaging |
Het |
| Rasal1 |
A |
G |
5: 120,812,670 (GRCm39) |
T565A |
probably benign |
Het |
| Rbm15 |
C |
A |
3: 107,238,471 (GRCm39) |
R642S |
probably damaging |
Het |
| Rpsa |
G |
A |
9: 119,960,069 (GRCm39) |
E211K |
possibly damaging |
Het |
| Ryr3 |
A |
G |
2: 112,517,155 (GRCm39) |
S3303P |
probably damaging |
Het |
| Scg2 |
T |
A |
1: 79,413,229 (GRCm39) |
N458I |
possibly damaging |
Het |
| Setx |
A |
G |
2: 29,069,655 (GRCm39) |
T2487A |
probably benign |
Het |
| Slc4a5 |
G |
A |
6: 83,244,549 (GRCm39) |
|
probably benign |
Het |
| Slc8a2 |
T |
A |
7: 15,874,914 (GRCm39) |
D387E |
probably benign |
Het |
| Smarcc2 |
A |
G |
10: 128,310,591 (GRCm39) |
T407A |
probably benign |
Het |
| Snap25 |
A |
G |
2: 136,619,384 (GRCm39) |
D179G |
probably damaging |
Het |
| Socs4 |
T |
C |
14: 47,527,325 (GRCm39) |
S74P |
probably benign |
Het |
| Sp6 |
T |
A |
11: 96,912,751 (GRCm39) |
Y155N |
probably benign |
Het |
| Srrt |
C |
T |
5: 137,294,389 (GRCm39) |
|
probably benign |
Het |
| Steap1 |
C |
T |
5: 5,786,431 (GRCm39) |
M335I |
probably benign |
Het |
| Stra6 |
A |
T |
9: 58,052,772 (GRCm39) |
Y250F |
probably benign |
Het |
| Svil |
T |
C |
18: 5,094,582 (GRCm39) |
S1421P |
probably damaging |
Het |
| Tcea3 |
G |
A |
4: 135,998,677 (GRCm39) |
C317Y |
probably damaging |
Het |
| Tmco6 |
T |
C |
18: 36,870,757 (GRCm39) |
L117S |
probably damaging |
Het |
| Trp53bp1 |
T |
C |
2: 121,100,718 (GRCm39) |
K89E |
probably damaging |
Het |
| Trp63 |
T |
A |
16: 25,583,052 (GRCm39) |
|
probably benign |
Het |
| Ube2d2a |
A |
G |
18: 35,933,185 (GRCm39) |
Y74C |
probably damaging |
Het |
| Usp19 |
T |
G |
9: 108,375,708 (GRCm39) |
F885V |
probably damaging |
Het |
| Utp18 |
T |
A |
11: 93,773,003 (GRCm39) |
|
probably benign |
Het |
| Vmn2r116 |
T |
C |
17: 23,620,387 (GRCm39) |
I707T |
possibly damaging |
Het |
| Vmn2r68 |
T |
A |
7: 84,882,457 (GRCm39) |
|
probably benign |
Het |
| Vmn2r68 |
C |
G |
7: 84,882,466 (GRCm39) |
|
probably null |
Het |
| Zfp318 |
C |
T |
17: 46,723,540 (GRCm39) |
P1848S |
probably benign |
Het |
| Zfp984 |
G |
T |
4: 147,839,722 (GRCm39) |
N376K |
probably benign |
Het |
|
| Other mutations in Cfap65 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01107:Cfap65
|
APN |
1 |
74,958,342 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01526:Cfap65
|
APN |
1 |
74,950,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01716:Cfap65
|
APN |
1 |
74,966,353 (GRCm39) |
missense |
probably benign |
|
|
IGL01780:Cfap65
|
APN |
1 |
74,967,507 (GRCm39) |
nonsense |
probably null |
|
|
IGL01993:Cfap65
|
APN |
1 |
74,959,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02164:Cfap65
|
APN |
1 |
74,967,304 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02350:Cfap65
|
APN |
1 |
74,967,507 (GRCm39) |
nonsense |
probably null |
|
|
IGL02357:Cfap65
|
APN |
1 |
74,967,507 (GRCm39) |
nonsense |
probably null |
|
|
IGL02576:Cfap65
|
APN |
1 |
74,942,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02756:Cfap65
|
APN |
1 |
74,944,239 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02792:Cfap65
|
APN |
1 |
74,966,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02874:Cfap65
|
APN |
1 |
74,950,267 (GRCm39) |
nonsense |
probably null |
|
|
IGL03101:Cfap65
|
APN |
1 |
74,967,592 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL03348:Cfap65
|
APN |
1 |
74,966,778 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03396:Cfap65
|
APN |
1 |
74,943,801 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4131001:Cfap65
|
UTSW |
1 |
74,967,501 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0077:Cfap65
|
UTSW |
1 |
74,971,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0227:Cfap65
|
UTSW |
1 |
74,971,117 (GRCm39) |
nonsense |
probably null |
|
|
R0312:Cfap65
|
UTSW |
1 |
74,943,226 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0331:Cfap65
|
UTSW |
1 |
74,968,461 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0331:Cfap65
|
UTSW |
1 |
74,968,460 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0347:Cfap65
|
UTSW |
1 |
74,965,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0359:Cfap65
|
UTSW |
1 |
74,959,760 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0361:Cfap65
|
UTSW |
1 |
74,964,599 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0465:Cfap65
|
UTSW |
1 |
74,956,043 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0549:Cfap65
|
UTSW |
1 |
74,957,603 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0646:Cfap65
|
UTSW |
1 |
74,941,328 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0734:Cfap65
|
UTSW |
1 |
74,958,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0763:Cfap65
|
UTSW |
1 |
74,943,841 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0990:Cfap65
|
UTSW |
1 |
74,960,678 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R1079:Cfap65
|
UTSW |
1 |
74,941,606 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1079:Cfap65
|
UTSW |
1 |
74,944,872 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1083:Cfap65
|
UTSW |
1 |
74,957,663 (GRCm39) |
splice site |
probably benign |
|
|
R1159:Cfap65
|
UTSW |
1 |
74,968,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1282:Cfap65
|
UTSW |
1 |
74,964,263 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1644:Cfap65
|
UTSW |
1 |
74,956,334 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1796:Cfap65
|
UTSW |
1 |
74,958,107 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1950:Cfap65
|
UTSW |
1 |
74,946,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2079:Cfap65
|
UTSW |
1 |
74,956,358 (GRCm39) |
missense |
probably benign |
0.30 |
|
R2132:Cfap65
|
UTSW |
1 |
74,946,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2136:Cfap65
|
UTSW |
1 |
74,956,432 (GRCm39) |
frame shift |
probably null |
|
|
R2219:Cfap65
|
UTSW |
1 |
74,943,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2220:Cfap65
|
UTSW |
1 |
74,943,184 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2291:Cfap65
|
UTSW |
1 |
74,965,634 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2417:Cfap65
|
UTSW |
1 |
74,966,345 (GRCm39) |
small insertion |
probably benign |
|
|
R3114:Cfap65
|
UTSW |
1 |
74,966,291 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4202:Cfap65
|
UTSW |
1 |
74,959,701 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4214:Cfap65
|
UTSW |
1 |
74,966,840 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4254:Cfap65
|
UTSW |
1 |
74,942,517 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4547:Cfap65
|
UTSW |
1 |
74,946,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4548:Cfap65
|
UTSW |
1 |
74,946,771 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4588:Cfap65
|
UTSW |
1 |
74,943,215 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4657:Cfap65
|
UTSW |
1 |
74,964,513 (GRCm39) |
intron |
probably benign |
|
|
R4701:Cfap65
|
UTSW |
1 |
74,958,067 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4755:Cfap65
|
UTSW |
1 |
74,967,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4820:Cfap65
|
UTSW |
1 |
74,966,791 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4831:Cfap65
|
UTSW |
1 |
74,956,454 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4866:Cfap65
|
UTSW |
1 |
74,964,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4869:Cfap65
|
UTSW |
1 |
74,958,420 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4881:Cfap65
|
UTSW |
1 |
74,946,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4884:Cfap65
|
UTSW |
1 |
74,942,283 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R4950:Cfap65
|
UTSW |
1 |
74,945,495 (GRCm39) |
nonsense |
probably null |
|
|
R5074:Cfap65
|
UTSW |
1 |
74,962,137 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5083:Cfap65
|
UTSW |
1 |
74,945,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5164:Cfap65
|
UTSW |
1 |
74,965,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5268:Cfap65
|
UTSW |
1 |
74,964,061 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5333:Cfap65
|
UTSW |
1 |
74,942,334 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5417:Cfap65
|
UTSW |
1 |
74,964,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5582:Cfap65
|
UTSW |
1 |
74,946,677 (GRCm39) |
intron |
probably benign |
|
|
R5669:Cfap65
|
UTSW |
1 |
74,964,127 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6010:Cfap65
|
UTSW |
1 |
74,962,190 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6084:Cfap65
|
UTSW |
1 |
74,959,564 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6112:Cfap65
|
UTSW |
1 |
74,942,298 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6425:Cfap65
|
UTSW |
1 |
74,966,868 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6677:Cfap65
|
UTSW |
1 |
74,943,844 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6693:Cfap65
|
UTSW |
1 |
74,956,445 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6838:Cfap65
|
UTSW |
1 |
74,971,180 (GRCm39) |
missense |
probably benign |
0.06 |
|
R6861:Cfap65
|
UTSW |
1 |
74,964,274 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6958:Cfap65
|
UTSW |
1 |
74,971,058 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R7134:Cfap65
|
UTSW |
1 |
74,965,792 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7320:Cfap65
|
UTSW |
1 |
74,965,763 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7340:Cfap65
|
UTSW |
1 |
74,960,742 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7426:Cfap65
|
UTSW |
1 |
74,959,585 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7529:Cfap65
|
UTSW |
1 |
74,965,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7634:Cfap65
|
UTSW |
1 |
74,941,593 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7654:Cfap65
|
UTSW |
1 |
74,972,303 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7704:Cfap65
|
UTSW |
1 |
74,967,527 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7727:Cfap65
|
UTSW |
1 |
74,965,784 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7895:Cfap65
|
UTSW |
1 |
74,972,321 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8215:Cfap65
|
UTSW |
1 |
74,949,902 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8344:Cfap65
|
UTSW |
1 |
74,967,203 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8345:Cfap65
|
UTSW |
1 |
74,967,203 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8413:Cfap65
|
UTSW |
1 |
74,956,328 (GRCm39) |
nonsense |
probably null |
|
|
R8431:Cfap65
|
UTSW |
1 |
74,967,203 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8432:Cfap65
|
UTSW |
1 |
74,967,203 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8528:Cfap65
|
UTSW |
1 |
74,945,096 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8809:Cfap65
|
UTSW |
1 |
74,942,382 (GRCm39) |
missense |
probably benign |
0.43 |
|
R8996:Cfap65
|
UTSW |
1 |
74,941,347 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9020:Cfap65
|
UTSW |
1 |
74,959,552 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9043:Cfap65
|
UTSW |
1 |
74,943,847 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9127:Cfap65
|
UTSW |
1 |
74,958,510 (GRCm39) |
splice site |
probably benign |
|
|
R9187:Cfap65
|
UTSW |
1 |
74,956,517 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9210:Cfap65
|
UTSW |
1 |
74,959,567 (GRCm39) |
missense |
probably benign |
|
|
R9212:Cfap65
|
UTSW |
1 |
74,959,567 (GRCm39) |
missense |
probably benign |
|
|
R9273:Cfap65
|
UTSW |
1 |
74,960,769 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9454:Cfap65
|
UTSW |
1 |
74,944,210 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9514:Cfap65
|
UTSW |
1 |
74,945,468 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9595:Cfap65
|
UTSW |
1 |
74,946,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9721:Cfap65
|
UTSW |
1 |
74,958,501 (GRCm39) |
missense |
probably benign |
0.16 |
|
R9742:Cfap65
|
UTSW |
1 |
74,943,840 (GRCm39) |
missense |
probably benign |
0.08 |
|
RF009:Cfap65
|
UTSW |
1 |
74,944,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Cfap65
|
UTSW |
1 |
74,949,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGATGGGATCACCAGGTATCCACAG -3'
(R):5'- GTGGCTTCCTCAGTATGATGCACAG -3'
Sequencing Primer
(F):5'- ACAGTGCTTTCCCACAATGG -3'
(R):5'- CAAATCTGGGACTAGAACCTTTC -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation