Incidental Mutation 'R6599:Vmn1r87'
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ID525115
Institutional Source Beutler Lab
Gene Symbol Vmn1r87
Ensembl Gene ENSMUSG00000070815
Gene Namevomeronasal 1 receptor 87
SynonymsV1rk1
MMRRC Submission
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.050) question?
Stock #R6599 (G1)
Quality Score225.009
Status Validated
Chromosome7
Chromosomal Location13130904-13140157 bp(-) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) T to A at 13131959 bp
ZygosityHeterozygous
Amino Acid Change Lysine to Stop codon at position 134 (K134*)
Ref Sequence ENSEMBL: ENSMUSP00000154184 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000094827] [ENSMUST00000211249] [ENSMUST00000227443] [ENSMUST00000228800]
Predicted Effect probably null
Transcript: ENSMUST00000094827
AA Change: K134*
SMART Domains Protein: ENSMUSP00000092422
Gene: ENSMUSG00000070815
AA Change: K134*

DomainStartEndE-ValueType
Pfam:TAS2R 1 285 1.2e-11 PFAM
Pfam:V1R 14 280 1.8e-36 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000211249
AA Change: K134*
Predicted Effect probably null
Transcript: ENSMUST00000227443
AA Change: K134*
Predicted Effect probably null
Transcript: ENSMUST00000228800
AA Change: K134*
Meta Mutation Damage Score 0.6652 question?
Coding Region Coverage
  • 1x: 99.9%
  • 3x: 99.7%
  • 10x: 98.6%
  • 20x: 95.9%
Validation Efficiency 94% (32/34)
Allele List at MGI
Other mutations in this stock
Total: 38 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930579F01Rik T C 3: 138,176,489 H150R probably benign Het
Acbd5 C T 2: 23,069,080 probably benign Het
Adcyap1r1 G A 6: 55,479,994 V237M probably damaging Het
Akr1c6 T G 13: 4,449,319 probably null Het
BC037034 G T 5: 138,263,458 probably null Het
Ccdc7b T A 8: 129,166,981 F96L probably benign Het
Cubn T C 2: 13,310,673 H2983R possibly damaging Het
Dhx40 T A 11: 86,804,349 I112L possibly damaging Het
Dnmbp A T 19: 43,856,586 D1070E probably damaging Het
Eml2 G A 7: 19,201,163 V432I probably damaging Het
Ep300 G C 15: 81,586,713 D29H unknown Het
Exoc3 T C 13: 74,189,158 probably null Het
Fuk A T 8: 110,893,283 probably null Het
Gm6401 C A 14: 41,966,864 E83* probably null Het
Gm8267 G T 14: 44,717,910 T218K possibly damaging Het
Hif3a T A 7: 17,042,605 D470V possibly damaging Het
Hist1h1d T C 13: 23,555,277 probably null Het
Igf2r T C 17: 12,698,618 S1526G possibly damaging Het
Lrp2 T C 2: 69,469,405 D3101G probably damaging Het
Megf6 A G 4: 154,258,087 probably null Het
Mthfs G A 9: 89,239,908 G149D probably damaging Het
Nnmt T C 9: 48,603,369 D116G probably benign Het
Nqo2 T C 13: 33,979,556 F22S probably damaging Het
Olfr389 T A 11: 73,776,680 M216L probably benign Het
Olfr869 T C 9: 20,137,943 S276P probably damaging Het
Parm1 T C 5: 91,593,859 S29P possibly damaging Het
Prokr2 C T 2: 132,373,549 V331M possibly damaging Het
Ptch1 T A 13: 63,523,104 I871F probably damaging Het
Rps6ka5 C A 12: 100,597,909 G227V probably damaging Het
Tcaim C T 9: 122,834,779 Q445* probably null Het
Trpc7 T C 13: 56,810,380 probably null Het
Ubxn7 A G 16: 32,384,925 E465G probably damaging Het
Unk G A 11: 116,047,802 R77Q probably damaging Het
Vmn1r226 A T 17: 20,688,289 N261I probably benign Het
Vmn2r10 T A 5: 108,996,078 I669L probably benign Het
Vmn2r115 A G 17: 23,346,032 I298V probably benign Het
Yipf2 T C 9: 21,589,848 K85E probably damaging Het
Zfp979 A T 4: 147,613,626 C209S probably benign Het
Other mutations in Vmn1r87
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01400:Vmn1r87 APN 7 13132303 missense probably damaging 1.00
IGL01577:Vmn1r87 APN 7 13131848 missense probably benign 0.00
IGL02972:Vmn1r87 APN 7 13132329 nonsense probably null
IGL03246:Vmn1r87 APN 7 13132361 utr 5 prime probably benign
PIT4142001:Vmn1r87 UTSW 7 13132185 missense probably benign 0.00
R0153:Vmn1r87 UTSW 7 13132284 missense probably damaging 1.00
R0502:Vmn1r87 UTSW 7 13131656 missense probably damaging 1.00
R0658:Vmn1r87 UTSW 7 13131829 missense probably damaging 1.00
R1589:Vmn1r87 UTSW 7 13131776 missense possibly damaging 0.46
R1731:Vmn1r87 UTSW 7 13131776 missense possibly damaging 0.46
R2027:Vmn1r87 UTSW 7 13131896 missense probably damaging 0.99
R2044:Vmn1r87 UTSW 7 13131821 missense probably benign 0.02
R3124:Vmn1r87 UTSW 7 13131566 missense probably damaging 1.00
R4208:Vmn1r87 UTSW 7 13132258 missense probably benign 0.37
R4731:Vmn1r87 UTSW 7 13132327 missense possibly damaging 0.92
R4732:Vmn1r87 UTSW 7 13132327 missense possibly damaging 0.92
R4733:Vmn1r87 UTSW 7 13132327 missense possibly damaging 0.92
R5079:Vmn1r87 UTSW 7 13132326 missense probably benign 0.01
R5125:Vmn1r87 UTSW 7 13131865 missense possibly damaging 0.79
R5178:Vmn1r87 UTSW 7 13131865 missense possibly damaging 0.79
R7067:Vmn1r87 UTSW 7 13131922 missense probably benign 0.02
R7560:Vmn1r87 UTSW 7 13131818 missense not run
X0028:Vmn1r87 UTSW 7 13131983 missense possibly damaging 0.52
Predicted Primers PCR Primer
(F):5'- AAACTGTGGACATGCCGTGTAC -3'
(R):5'- GCATACAGTGTTACTAGGGGCC -3'

Sequencing Primer
(F):5'- GGACATGCCGTGTACTCCTATTG -3'
(R):5'- ATACAGTGTTACTAGGGGCCTTTCC -3'
Posted On2018-06-22