Incidental Mutation 'PIT4812001:Clip1'
| ID |
556904 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Clip1
|
| Ensembl Gene |
ENSMUSG00000049550 |
| Gene Name |
CAP-GLY domain containing linker protein 1 |
| Synonyms |
Rsn, CLIP-170, 4631429H07Rik, restin, Clip 170, 1110007I12Rik, Clip50, cytoplasmic linker protein 50 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
PIT4812001 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
5 |
| Chromosomal Location |
123715857-123822527 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 123768738 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Serine
at position 620
(R620S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000107190
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000031382]
[ENSMUST00000063905]
[ENSMUST00000111561]
[ENSMUST00000111564]
[ENSMUST00000111566]
[ENSMUST00000149410]
|
| AlphaFold |
Q922J3 |
| PDB Structure |
Solution structure of the 1st CAP-Gly domain in mouse CLIP-170/restin [SOLUTION NMR]
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000031382
AA Change: R666S
PolyPhen 2
Score 0.277 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000031382
Gene: ENSMUSG00000049550
AA Change: R666S
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.28e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
451 |
N/A |
INTRINSIC |
|
coiled coil region
|
474 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
581 |
620 |
N/A |
INTRINSIC |
|
coiled coil region
|
652 |
1352 |
N/A |
INTRINSIC |
|
low complexity region
|
1362 |
1373 |
N/A |
INTRINSIC |
|
Pfam:CLIP1_ZNF
|
1375 |
1392 |
5.8e-9 |
PFAM |
|
ZnF_C2HC
|
1417 |
1433 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000063905
AA Change: R655S
PolyPhen 2
Score 0.008 (Sensitivity: 0.96; Specificity: 0.76)
|
| SMART Domains |
Protein: ENSMUSP00000068241
Gene: ENSMUSG00000049550
AA Change: R655S
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
3.3e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1075 |
N/A |
INTRINSIC |
|
coiled coil region
|
1115 |
1235 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1256 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1300 |
1316 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111561
AA Change: R655S
PolyPhen 2
Score 0.210 (Sensitivity: 0.92; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000107186
Gene: ENSMUSG00000049550
AA Change: R655S
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
1.93e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
524 |
N/A |
INTRINSIC |
|
coiled coil region
|
570 |
609 |
N/A |
INTRINSIC |
|
coiled coil region
|
641 |
1341 |
N/A |
INTRINSIC |
|
low complexity region
|
1351 |
1362 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1406 |
1422 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111564
AA Change: R620S
PolyPhen 2
Score 0.083 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000107190
Gene: ENSMUSG00000049550
AA Change: R620S
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2.5e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1230 |
N/A |
INTRINSIC |
|
low complexity region
|
1240 |
1251 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1295 |
1311 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000111566
AA Change: R620S
PolyPhen 2
Score 0.099 (Sensitivity: 0.93; Specificity: 0.85)
|
| SMART Domains |
Protein: ENSMUSP00000107192
Gene: ENSMUSG00000049550
AA Change: R620S
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_2
|
11 |
53 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
internal_repeat_2
|
140 |
177 |
2e-5 |
PROSPERO |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
349 |
489 |
N/A |
INTRINSIC |
|
coiled coil region
|
535 |
574 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1316 |
1327 |
N/A |
INTRINSIC |
|
ZnF_C2HC
|
1371 |
1387 |
1.45e0 |
SMART |
|
| Predicted Effect |
|
| SMART Domains |
Protein: ENSMUSP00000121425
Gene: ENSMUSG00000049550
AA Change: R407S
| Domain | Start | End | E-Value | Type |
|---|
|
CAP_GLY
|
2 |
31 |
2.59e0 |
SMART |
|
low complexity region
|
39 |
57 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
84 |
N/A |
INTRINSIC |
|
coiled coil region
|
101 |
276 |
N/A |
INTRINSIC |
|
coiled coil region
|
322 |
361 |
N/A |
INTRINSIC |
|
coiled coil region
|
393 |
980 |
N/A |
INTRINSIC |
|
low complexity region
|
991 |
1002 |
N/A |
INTRINSIC |
|
Pfam:CLIP1_ZNF
|
1004 |
1021 |
4.2e-9 |
PFAM |
|
ZnF_C2HC
|
1046 |
1062 |
1.45e0 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000144121
|
| SMART Domains |
Protein: ENSMUSP00000119641
Gene: ENSMUSG00000049550
| Domain | Start | End | E-Value | Type |
|---|
|
CAP_GLY
|
37 |
102 |
1.05e-31 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000149410
AA Change: R589S
PolyPhen 2
Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000115965
Gene: ENSMUSG00000049550
AA Change: R589S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
26 |
32 |
N/A |
INTRINSIC |
|
CAP_GLY
|
60 |
125 |
1.05e-31 |
SMART |
|
CAP_GLY
|
213 |
278 |
4.69e-34 |
SMART |
|
low complexity region
|
286 |
304 |
N/A |
INTRINSIC |
|
low complexity region
|
305 |
331 |
N/A |
INTRINSIC |
|
coiled coil region
|
334 |
458 |
N/A |
INTRINSIC |
|
coiled coil region
|
504 |
543 |
N/A |
INTRINSIC |
|
coiled coil region
|
575 |
827 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 93.8%
- 3x: 91.0%
- 10x: 85.3%
- 20x: 73.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
PHENOTYPE: Mice homozygous for a targeted allele display reduced male fertility and teratozoospermia. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 61 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4921524L21Rik |
T |
C |
18: 6,630,053 (GRCm39) |
S252P |
possibly damaging |
Het |
| 4933409G03Rik |
G |
A |
2: 68,419,292 (GRCm39) |
V14I |
probably benign |
Het |
| Adgrf5 |
T |
G |
17: 43,761,260 (GRCm39) |
V985G |
probably damaging |
Het |
| Ankrd44 |
A |
T |
1: 54,762,197 (GRCm39) |
Y542* |
probably null |
Het |
| Atp13a3 |
T |
C |
16: 30,181,396 (GRCm39) |
T75A |
probably damaging |
Het |
| Atr |
T |
C |
9: 95,792,702 (GRCm39) |
F1675L |
probably benign |
Het |
| Atrnl1 |
A |
G |
19: 57,720,055 (GRCm39) |
I1082V |
probably benign |
Het |
| Cped1 |
T |
C |
6: 22,122,293 (GRCm39) |
F391S |
probably benign |
Het |
| Cracr2a |
T |
C |
6: 127,602,833 (GRCm39) |
L230P |
probably damaging |
Het |
| Dctn1 |
T |
A |
6: 83,176,744 (GRCm39) |
V1266E |
possibly damaging |
Het |
| Dlg1 |
T |
A |
16: 31,665,703 (GRCm39) |
F687I |
probably benign |
Het |
| Dnah8 |
C |
A |
17: 30,927,419 (GRCm39) |
D1358E |
probably benign |
Het |
| Dnajc11 |
A |
G |
4: 152,037,346 (GRCm39) |
R84G |
probably benign |
Het |
| Dnajc14 |
C |
A |
10: 128,642,552 (GRCm39) |
T158N |
probably damaging |
Het |
| Dscc1 |
A |
G |
15: 54,945,657 (GRCm39) |
L346P |
probably damaging |
Het |
| Efcab3 |
A |
G |
11: 104,990,805 (GRCm39) |
I71V |
probably null |
Het |
| Erbb3 |
T |
A |
10: 128,410,248 (GRCm39) |
Q670L |
possibly damaging |
Het |
| Ercc4 |
G |
A |
16: 12,962,311 (GRCm39) |
E652K |
probably benign |
Het |
| Ercc6l2 |
T |
A |
13: 64,006,071 (GRCm39) |
V591D |
possibly damaging |
Het |
| Fam3c |
C |
T |
6: 22,321,369 (GRCm39) |
G134E |
probably damaging |
Het |
| Frmd5 |
A |
G |
2: 121,416,927 (GRCm39) |
V70A |
probably benign |
Het |
| Gjd3 |
A |
T |
11: 102,691,807 (GRCm39) |
Y65* |
probably null |
Het |
| Gm3033 |
A |
C |
14: 3,848,891 (GRCm38) |
L137F |
|
Het |
| Gria4 |
C |
A |
9: 4,427,128 (GRCm39) |
A771S |
probably damaging |
Het |
| Hc |
A |
G |
2: 34,919,464 (GRCm39) |
L674P |
probably benign |
Het |
| Hjurp |
CTCTGGGAGGGCTTGCTCCGGGGGCAGTGTGTCCTGTTCTTGTGCAGCCCCT |
C |
1: 88,193,999 (GRCm39) |
|
probably benign |
Het |
| Hycc2 |
T |
G |
1: 58,587,862 (GRCm39) |
D117A |
possibly damaging |
Het |
| Inpp5f |
A |
T |
7: 128,294,032 (GRCm39) |
Y696F |
probably benign |
Het |
| Itga11 |
C |
A |
9: 62,639,475 (GRCm39) |
Q157K |
probably damaging |
Het |
| Itgb5 |
G |
T |
16: 33,740,357 (GRCm39) |
C489F |
probably damaging |
Het |
| Klhl38 |
C |
T |
15: 58,185,938 (GRCm39) |
G264S |
probably benign |
Het |
| Krt78 |
C |
T |
15: 101,856,504 (GRCm39) |
V436M |
probably damaging |
Het |
| Mia2 |
A |
T |
12: 59,148,365 (GRCm39) |
D75V |
possibly damaging |
Het |
| Mphosph6 |
T |
A |
8: 118,525,888 (GRCm39) |
Q20L |
probably damaging |
Het |
| Ogfr |
C |
T |
2: 180,237,304 (GRCm39) |
P630S |
possibly damaging |
Het |
| Or2c1 |
A |
T |
16: 3,657,394 (GRCm39) |
K186* |
probably null |
Het |
| Or4c11 |
G |
A |
2: 88,695,314 (GRCm39) |
V122M |
probably benign |
Het |
| Or5an9 |
T |
G |
19: 12,187,617 (GRCm39) |
I229S |
probably damaging |
Het |
| Pbx3 |
T |
C |
2: 34,114,631 (GRCm39) |
E101G |
probably damaging |
Het |
| Pcca |
T |
A |
14: 123,027,794 (GRCm39) |
N587K |
probably benign |
Het |
| Pdia3 |
G |
T |
2: 121,264,011 (GRCm39) |
A287S |
probably damaging |
Het |
| Pfas |
T |
A |
11: 68,880,862 (GRCm39) |
D209V |
|
Het |
| Pramel29 |
A |
G |
4: 143,936,086 (GRCm39) |
I56T |
probably benign |
Het |
| Pter |
A |
T |
2: 12,985,179 (GRCm39) |
I170F |
probably damaging |
Het |
| Ptprq |
A |
T |
10: 107,502,428 (GRCm39) |
V830E |
probably damaging |
Het |
| Rab11fip5 |
T |
C |
6: 85,318,540 (GRCm39) |
D783G |
probably benign |
Het |
| Rbm19 |
T |
C |
5: 120,266,315 (GRCm39) |
V446A |
possibly damaging |
Het |
| Selp |
A |
G |
1: 163,959,832 (GRCm39) |
N363D |
probably benign |
Het |
| Six2 |
C |
A |
17: 85,992,729 (GRCm39) |
S258I |
possibly damaging |
Het |
| Smc1b |
A |
G |
15: 84,953,852 (GRCm39) |
V1139A |
possibly damaging |
Het |
| Sp1 |
A |
G |
15: 102,316,843 (GRCm39) |
T121A |
possibly damaging |
Het |
| Sucla2 |
A |
T |
14: 73,816,889 (GRCm39) |
I210L |
possibly damaging |
Het |
| Trank1 |
T |
C |
9: 111,176,980 (GRCm39) |
L339P |
probably damaging |
Het |
| Ttll5 |
T |
A |
12: 85,973,635 (GRCm39) |
D794E |
probably benign |
Het |
| Usp32 |
C |
T |
11: 84,900,900 (GRCm39) |
V1107I |
probably damaging |
Het |
| Vmn1r195 |
T |
C |
13: 22,463,033 (GRCm39) |
Y168H |
probably benign |
Het |
| Vmn1r223 |
A |
G |
13: 23,434,060 (GRCm39) |
N218S |
probably damaging |
Het |
| Vmn2r25 |
T |
A |
6: 123,800,447 (GRCm39) |
S632C |
probably damaging |
Het |
| Vwa3a |
A |
T |
7: 120,375,356 (GRCm39) |
K390I |
probably damaging |
Het |
| Zfp442 |
A |
T |
2: 150,251,661 (GRCm39) |
C80* |
probably null |
Het |
| Zic1 |
A |
T |
9: 91,246,394 (GRCm39) |
I226N |
probably damaging |
Het |
|
| Other mutations in Clip1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00159:Clip1
|
APN |
5 |
123,741,717 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01067:Clip1
|
APN |
5 |
123,768,867 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01524:Clip1
|
APN |
5 |
123,717,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01632:Clip1
|
APN |
5 |
123,755,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01798:Clip1
|
APN |
5 |
123,721,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01874:Clip1
|
APN |
5 |
123,741,729 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL01908:Clip1
|
APN |
5 |
123,761,270 (GRCm39) |
splice site |
probably benign |
|
|
IGL02120:Clip1
|
APN |
5 |
123,785,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02309:Clip1
|
APN |
5 |
123,755,763 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02555:Clip1
|
APN |
5 |
123,759,857 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03027:Clip1
|
APN |
5 |
123,759,919 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL03336:Clip1
|
APN |
5 |
123,791,633 (GRCm39) |
nonsense |
probably null |
|
|
IGL03365:Clip1
|
APN |
5 |
123,721,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02802:Clip1
|
UTSW |
5 |
123,769,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0254:Clip1
|
UTSW |
5 |
123,755,395 (GRCm39) |
splice site |
probably benign |
|
|
R0401:Clip1
|
UTSW |
5 |
123,791,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0530:Clip1
|
UTSW |
5 |
123,778,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0744:Clip1
|
UTSW |
5 |
123,768,784 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0833:Clip1
|
UTSW |
5 |
123,768,784 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1116:Clip1
|
UTSW |
5 |
123,717,554 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1182:Clip1
|
UTSW |
5 |
123,785,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1656:Clip1
|
UTSW |
5 |
123,768,466 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1700:Clip1
|
UTSW |
5 |
123,768,433 (GRCm39) |
missense |
probably benign |
|
|
R1889:Clip1
|
UTSW |
5 |
123,791,559 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1975:Clip1
|
UTSW |
5 |
123,761,281 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2406:Clip1
|
UTSW |
5 |
123,741,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3545:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3548:Clip1
|
UTSW |
5 |
123,769,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3911:Clip1
|
UTSW |
5 |
123,728,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3944:Clip1
|
UTSW |
5 |
123,755,892 (GRCm39) |
unclassified |
probably benign |
|
|
R4660:Clip1
|
UTSW |
5 |
123,717,437 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4784:Clip1
|
UTSW |
5 |
123,717,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4785:Clip1
|
UTSW |
5 |
123,717,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4824:Clip1
|
UTSW |
5 |
123,769,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4831:Clip1
|
UTSW |
5 |
123,721,664 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4951:Clip1
|
UTSW |
5 |
123,768,408 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4960:Clip1
|
UTSW |
5 |
123,792,066 (GRCm39) |
nonsense |
probably null |
|
|
R5014:Clip1
|
UTSW |
5 |
123,755,793 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5116:Clip1
|
UTSW |
5 |
123,768,770 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5212:Clip1
|
UTSW |
5 |
123,768,744 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5238:Clip1
|
UTSW |
5 |
123,785,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5318:Clip1
|
UTSW |
5 |
123,751,147 (GRCm39) |
unclassified |
probably benign |
|
|
R5372:Clip1
|
UTSW |
5 |
123,768,303 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5701:Clip1
|
UTSW |
5 |
123,751,366 (GRCm39) |
unclassified |
probably benign |
|
|
R5734:Clip1
|
UTSW |
5 |
123,753,217 (GRCm39) |
unclassified |
probably benign |
|
|
R5757:Clip1
|
UTSW |
5 |
123,765,460 (GRCm39) |
missense |
probably benign |
0.21 |
|
R6024:Clip1
|
UTSW |
5 |
123,753,152 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6160:Clip1
|
UTSW |
5 |
123,751,604 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6177:Clip1
|
UTSW |
5 |
123,751,897 (GRCm39) |
unclassified |
probably benign |
|
|
R6183:Clip1
|
UTSW |
5 |
123,780,667 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6377:Clip1
|
UTSW |
5 |
123,741,717 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R6436:Clip1
|
UTSW |
5 |
123,779,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6471:Clip1
|
UTSW |
5 |
123,778,612 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6766:Clip1
|
UTSW |
5 |
123,752,827 (GRCm39) |
unclassified |
probably benign |
|
|
R7015:Clip1
|
UTSW |
5 |
123,751,675 (GRCm39) |
unclassified |
probably benign |
|
|
R7094:Clip1
|
UTSW |
5 |
123,761,333 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7143:Clip1
|
UTSW |
5 |
123,791,673 (GRCm39) |
missense |
probably benign |
|
|
R7222:Clip1
|
UTSW |
5 |
123,749,904 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7233:Clip1
|
UTSW |
5 |
123,749,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Clip1
|
UTSW |
5 |
123,751,328 (GRCm39) |
missense |
|
|
|
R7249:Clip1
|
UTSW |
5 |
123,741,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7283:Clip1
|
UTSW |
5 |
123,751,857 (GRCm39) |
missense |
|
|
|
R7295:Clip1
|
UTSW |
5 |
123,765,419 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7447:Clip1
|
UTSW |
5 |
123,791,696 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7458:Clip1
|
UTSW |
5 |
123,778,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7483:Clip1
|
UTSW |
5 |
123,755,447 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7516:Clip1
|
UTSW |
5 |
123,721,448 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7619:Clip1
|
UTSW |
5 |
123,752,342 (GRCm39) |
missense |
|
|
|
R7831:Clip1
|
UTSW |
5 |
123,751,342 (GRCm39) |
missense |
|
|
|
R7897:Clip1
|
UTSW |
5 |
123,760,861 (GRCm39) |
missense |
probably benign |
|
|
R8155:Clip1
|
UTSW |
5 |
123,751,699 (GRCm39) |
missense |
|
|
|
R8157:Clip1
|
UTSW |
5 |
123,768,782 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8232:Clip1
|
UTSW |
5 |
123,785,981 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8396:Clip1
|
UTSW |
5 |
123,780,627 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8446:Clip1
|
UTSW |
5 |
123,794,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8486:Clip1
|
UTSW |
5 |
123,752,770 (GRCm39) |
unclassified |
probably benign |
|
|
R8511:Clip1
|
UTSW |
5 |
123,791,969 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8731:Clip1
|
UTSW |
5 |
123,752,756 (GRCm39) |
missense |
|
|
|
R8889:Clip1
|
UTSW |
5 |
123,717,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8892:Clip1
|
UTSW |
5 |
123,717,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9058:Clip1
|
UTSW |
5 |
123,752,645 (GRCm39) |
missense |
|
|
|
R9106:Clip1
|
UTSW |
5 |
123,753,223 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9212:Clip1
|
UTSW |
5 |
123,721,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9217:Clip1
|
UTSW |
5 |
123,717,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9223:Clip1
|
UTSW |
5 |
123,784,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9325:Clip1
|
UTSW |
5 |
123,751,186 (GRCm39) |
missense |
|
|
|
R9752:Clip1
|
UTSW |
5 |
123,760,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Clip1
|
UTSW |
5 |
123,755,413 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATTTCCACTAGGTGCTGGTC -3'
(R):5'- ACGGCCACTGAGAAGCTTTC -3'
Sequencing Primer
(F):5'- CCACTAGGTGCTGGTCTTCTG -3'
(R):5'- TTTCCAAAGAGAACGAGTCCCTGAG -3'
|
| Posted On |
2019-06-07 |
Incidental Mutation