Mutagenetix > Incidental Mutation

Incidental Mutation 'PIT4812001:Efcab3'

556925

Institutional Source

Beutler Lab

Gene Symbol

Efcab3

Ensembl Gene

ENSMUSG00000020690

Gene Name

EF-hand calcium binding domain 3

Synonyms

Gm11639, Efcab13, 4921510J17Rik, Efcab15, Gm11639

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

PIT4812001 (G1)

Quality Score

225.009

Status

Not validated

Chromosome

Chromosomal Location

104954418-105008363 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 104990805 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Valine at position 71 (I71V)

Ref Sequence

ENSEMBL: ENSMUSP00000021029 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000021029] [ENSMUST00000137086] [ENSMUST00000212287]

AlphaFold

Q80X60

Predicted Effect

probably null
Transcript: ENSMUST00000021029
AA Change: I71V

PolyPhen 2 Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)

SMART Domains

Protein: ENSMUSP00000021029
Gene: ENSMUSG00000020690
AA Change: I71V

Domain	Start	End	E-Value	Type
Pfam:EF-hand_8	61	113	1e-10	PFAM
low complexity region	394	417	N/A	INTRINSIC
low complexity region	420	428	N/A	INTRINSIC

Predicted Effect

probably null
Transcript: ENSMUST00000137086
AA Change: I279V

PolyPhen 2 Score 0.025 (Sensitivity: 0.95; Specificity: 0.81)

SMART Domains

Protein: ENSMUSP00000114580
Gene: ENSMUSG00000020690
AA Change: I279V

Domain	Start	End	E-Value	Type
internal_repeat_1	4	78	5.46e-7	PROSPERO
EFh	102	130	2.18e1	SMART
EFh	155	183	4.93e0	SMART
Blast:EFh	257	285	3e-7	BLAST
EFh	293	321	1.03e0	SMART

Predicted Effect

probably null
Transcript: ENSMUST00000212287
AA Change: I5447V

PolyPhen 2 Score 0.870 (Sensitivity: 0.83; Specificity: 0.93)

Coding Region Coverage

1x: 93.8%
3x: 91.0%
10x: 85.3%
20x: 73.0%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 61 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4921524L21Rik	T	C	18: 6,630,053 (GRCm39)	S252P	possibly damaging	Het
4933409G03Rik	G	A	2: 68,419,292 (GRCm39)	V14I	probably benign	Het
Adgrf5	T	G	17: 43,761,260 (GRCm39)	V985G	probably damaging	Het
Ankrd44	A	T	1: 54,762,197 (GRCm39)	Y542*	probably null	Het
Atp13a3	T	C	16: 30,181,396 (GRCm39)	T75A	probably damaging	Het
Atr	T	C	9: 95,792,702 (GRCm39)	F1675L	probably benign	Het
Atrnl1	A	G	19: 57,720,055 (GRCm39)	I1082V	probably benign	Het
Clip1	T	A	5: 123,768,738 (GRCm39)	R620S	probably benign	Het
Cped1	T	C	6: 22,122,293 (GRCm39)	F391S	probably benign	Het
Cracr2a	T	C	6: 127,602,833 (GRCm39)	L230P	probably damaging	Het
Dctn1	T	A	6: 83,176,744 (GRCm39)	V1266E	possibly damaging	Het
Dlg1	T	A	16: 31,665,703 (GRCm39)	F687I	probably benign	Het
Dnah8	C	A	17: 30,927,419 (GRCm39)	D1358E	probably benign	Het
Dnajc11	A	G	4: 152,037,346 (GRCm39)	R84G	probably benign	Het
Dnajc14	C	A	10: 128,642,552 (GRCm39)	T158N	probably damaging	Het
Dscc1	A	G	15: 54,945,657 (GRCm39)	L346P	probably damaging	Het
Erbb3	T	A	10: 128,410,248 (GRCm39)	Q670L	possibly damaging	Het
Ercc4	G	A	16: 12,962,311 (GRCm39)	E652K	probably benign	Het
Ercc6l2	T	A	13: 64,006,071 (GRCm39)	V591D	possibly damaging	Het
Fam3c	C	T	6: 22,321,369 (GRCm39)	G134E	probably damaging	Het
Frmd5	A	G	2: 121,416,927 (GRCm39)	V70A	probably benign	Het
Gjd3	A	T	11: 102,691,807 (GRCm39)	Y65*	probably null	Het
Gm3033	A	C	14: 3,848,891 (GRCm38)	L137F		Het
Gria4	C	A	9: 4,427,128 (GRCm39)	A771S	probably damaging	Het
Hc	A	G	2: 34,919,464 (GRCm39)	L674P	probably benign	Het
Hjurp	CTCTGGGAGGGCTTGCTCCGGGGGCAGTGTGTCCTGTTCTTGTGCAGCCCCT	C	1: 88,193,999 (GRCm39)		probably benign	Het
Hycc2	T	G	1: 58,587,862 (GRCm39)	D117A	possibly damaging	Het
Inpp5f	A	T	7: 128,294,032 (GRCm39)	Y696F	probably benign	Het
Itga11	C	A	9: 62,639,475 (GRCm39)	Q157K	probably damaging	Het
Itgb5	G	T	16: 33,740,357 (GRCm39)	C489F	probably damaging	Het
Klhl38	C	T	15: 58,185,938 (GRCm39)	G264S	probably benign	Het
Krt78	C	T	15: 101,856,504 (GRCm39)	V436M	probably damaging	Het
Mia2	A	T	12: 59,148,365 (GRCm39)	D75V	possibly damaging	Het
Mphosph6	T	A	8: 118,525,888 (GRCm39)	Q20L	probably damaging	Het
Ogfr	C	T	2: 180,237,304 (GRCm39)	P630S	possibly damaging	Het
Or2c1	A	T	16: 3,657,394 (GRCm39)	K186*	probably null	Het
Or4c11	G	A	2: 88,695,314 (GRCm39)	V122M	probably benign	Het
Or5an9	T	G	19: 12,187,617 (GRCm39)	I229S	probably damaging	Het
Pbx3	T	C	2: 34,114,631 (GRCm39)	E101G	probably damaging	Het
Pcca	T	A	14: 123,027,794 (GRCm39)	N587K	probably benign	Het
Pdia3	G	T	2: 121,264,011 (GRCm39)	A287S	probably damaging	Het
Pfas	T	A	11: 68,880,862 (GRCm39)	D209V		Het
Pramel29	A	G	4: 143,936,086 (GRCm39)	I56T	probably benign	Het
Pter	A	T	2: 12,985,179 (GRCm39)	I170F	probably damaging	Het
Ptprq	A	T	10: 107,502,428 (GRCm39)	V830E	probably damaging	Het
Rab11fip5	T	C	6: 85,318,540 (GRCm39)	D783G	probably benign	Het
Rbm19	T	C	5: 120,266,315 (GRCm39)	V446A	possibly damaging	Het
Selp	A	G	1: 163,959,832 (GRCm39)	N363D	probably benign	Het
Six2	C	A	17: 85,992,729 (GRCm39)	S258I	possibly damaging	Het
Smc1b	A	G	15: 84,953,852 (GRCm39)	V1139A	possibly damaging	Het
Sp1	A	G	15: 102,316,843 (GRCm39)	T121A	possibly damaging	Het
Sucla2	A	T	14: 73,816,889 (GRCm39)	I210L	possibly damaging	Het
Trank1	T	C	9: 111,176,980 (GRCm39)	L339P	probably damaging	Het
Ttll5	T	A	12: 85,973,635 (GRCm39)	D794E	probably benign	Het
Usp32	C	T	11: 84,900,900 (GRCm39)	V1107I	probably damaging	Het
Vmn1r195	T	C	13: 22,463,033 (GRCm39)	Y168H	probably benign	Het
Vmn1r223	A	G	13: 23,434,060 (GRCm39)	N218S	probably damaging	Het
Vmn2r25	T	A	6: 123,800,447 (GRCm39)	S632C	probably damaging	Het
Vwa3a	A	T	7: 120,375,356 (GRCm39)	K390I	probably damaging	Het
Zfp442	A	T	2: 150,251,661 (GRCm39)	C80*	probably null	Het
Zic1	A	T	9: 91,246,394 (GRCm39)	I226N	probably damaging	Het

Other mutations in Efcab3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00897:Efcab3	APN	11	104,990,847 (GRCm39)	missense	probably damaging	1.00
IGL01308:Efcab3	APN	11	104,611,523 (GRCm39)	missense	probably benign	0.03
IGL01483:Efcab3	APN	11	104,630,173 (GRCm39)	missense	probably benign	0.03
IGL01695:Efcab3	APN	11	104,626,889 (GRCm39)	missense	probably damaging	1.00
IGL01860:Efcab3	APN	11	104,581,747 (GRCm39)	missense	probably benign	0.16
IGL01981:Efcab3	APN	11	104,612,258 (GRCm39)	intron	probably benign
IGL01984:Efcab3	APN	11	104,629,134 (GRCm39)	missense	probably benign	0.20
IGL02023:Efcab3	APN	11	104,612,258 (GRCm39)	intron	probably benign
IGL02252:Efcab3	APN	11	104,644,753 (GRCm39)	missense	possibly damaging	0.68
IGL02886:Efcab3	APN	11	104,986,700 (GRCm39)	missense	possibly damaging	0.95
IGL03116:Efcab3	APN	11	104,612,359 (GRCm39)	missense	probably benign	0.02
IGL03141:Efcab3	APN	11	104,986,696 (GRCm39)	missense	probably damaging	0.99
IGL03242:Efcab3	APN	11	104,997,230 (GRCm39)	missense	probably damaging	1.00
IGL03274:Efcab3	APN	11	104,611,919 (GRCm39)	missense	probably benign	0.03
IGL03408:Efcab3	APN	11	104,601,447 (GRCm39)	missense	probably benign	0.03
R0018:Efcab3	UTSW	11	104,612,378 (GRCm39)	critical splice donor site	probably null
R0068:Efcab3	UTSW	11	104,611,648 (GRCm39)	missense	probably benign	0.29
R0350:Efcab3	UTSW	11	104,581,706 (GRCm39)	missense	probably benign	0.03
R0388:Efcab3	UTSW	11	105,000,227 (GRCm39)	missense	possibly damaging	0.61
R0646:Efcab3	UTSW	11	104,611,327 (GRCm39)	missense	probably benign	0.03
R0668:Efcab3	UTSW	11	104,611,318 (GRCm39)	missense	probably benign	0.16
R0715:Efcab3	UTSW	11	104,611,706 (GRCm39)	missense	possibly damaging	0.90
R0944:Efcab3	UTSW	11	104,601,556 (GRCm39)	splice site	probably null
R1330:Efcab3	UTSW	11	104,637,116 (GRCm39)	missense	possibly damaging	0.84
R1440:Efcab3	UTSW	11	104,999,581 (GRCm39)	splice site	probably benign
R1508:Efcab3	UTSW	11	104,601,503 (GRCm39)	missense	probably benign	0.03
R1540:Efcab3	UTSW	11	104,999,726 (GRCm39)	missense	probably benign	0.07
R1643:Efcab3	UTSW	11	104,589,804 (GRCm39)	missense	probably benign	0.16
R1651:Efcab3	UTSW	11	104,611,492 (GRCm39)	missense	probably benign	0.03
R1665:Efcab3	UTSW	11	104,611,940 (GRCm39)	missense	probably benign	0.07
R1702:Efcab3	UTSW	11	104,581,832 (GRCm39)	missense	probably benign	0.03
R1711:Efcab3	UTSW	11	104,611,514 (GRCm39)	missense	probably benign	0.07
R1779:Efcab3	UTSW	11	104,611,765 (GRCm39)	missense	probably benign	0.15
R1813:Efcab3	UTSW	11	104,611,514 (GRCm39)	missense	probably benign	0.07
R1818:Efcab3	UTSW	11	104,612,333 (GRCm39)	missense	probably benign	0.10
R1896:Efcab3	UTSW	11	104,611,514 (GRCm39)	missense	probably benign	0.07
R1969:Efcab3	UTSW	11	104,637,090 (GRCm39)	missense	probably damaging	1.00
R2029:Efcab3	UTSW	11	104,990,851 (GRCm39)	missense	probably damaging	0.99
R2139:Efcab3	UTSW	11	104,642,737 (GRCm39)	missense	possibly damaging	0.53
R2165:Efcab3	UTSW	11	104,642,688 (GRCm39)	missense	possibly damaging	0.93
R2359:Efcab3	UTSW	11	104,630,106 (GRCm39)	missense	possibly damaging	0.80
R2394:Efcab3	UTSW	11	104,629,121 (GRCm39)	missense	probably benign	0.17
R2401:Efcab3	UTSW	11	104,963,144 (GRCm39)	critical splice donor site	probably null
R2406:Efcab3	UTSW	11	104,611,457 (GRCm39)	missense	probably benign	0.03
R2570:Efcab3	UTSW	11	104,624,490 (GRCm39)	missense	probably damaging	1.00
R3795:Efcab3	UTSW	11	104,624,501 (GRCm39)	missense	possibly damaging	0.94
R3901:Efcab3	UTSW	11	104,974,713 (GRCm39)	missense	possibly damaging	0.68
R4244:Efcab3	UTSW	11	105,002,629 (GRCm39)	missense	probably damaging	1.00
R4352:Efcab3	UTSW	11	104,630,140 (GRCm39)	missense	probably null	0.25
R4359:Efcab3	UTSW	11	104,624,547 (GRCm39)	splice site	probably null
R4424:Efcab3	UTSW	11	104,626,940 (GRCm39)	critical splice donor site	probably null
R4895:Efcab3	UTSW	11	104,611,112 (GRCm39)	missense	probably benign	0.16
R4895:Efcab3	UTSW	11	105,008,227 (GRCm39)	unclassified	probably benign
R4895:Efcab3	UTSW	11	104,640,496 (GRCm39)	missense	probably damaging	1.00
R5006:Efcab3	UTSW	11	104,620,503 (GRCm39)	splice site	probably null
R5066:Efcab3	UTSW	11	104,611,490 (GRCm39)	missense	probably benign	0.03
R5316:Efcab3	UTSW	11	104,967,286 (GRCm39)	missense	possibly damaging	0.80
R5329:Efcab3	UTSW	11	104,644,632 (GRCm39)	splice site	probably null
R5405:Efcab3	UTSW	11	104,612,018 (GRCm39)	missense	probably benign	0.07
R5814:Efcab3	UTSW	11	104,626,940 (GRCm39)	critical splice donor site	probably benign
R5888:Efcab3	UTSW	11	104,612,227 (GRCm39)	splice site	probably benign
R5910:Efcab3	UTSW	11	104,581,760 (GRCm39)	missense	probably benign	0.01
R5975:Efcab3	UTSW	11	104,578,375 (GRCm39)	start gained	probably benign
R6019:Efcab3	UTSW	11	104,933,728 (GRCm39)	critical splice donor site	probably null
R6028:Efcab3	UTSW	11	104,660,481 (GRCm39)	critical splice donor site	probably null
R6048:Efcab3	UTSW	11	104,835,259 (GRCm39)	missense	unknown
R6059:Efcab3	UTSW	11	104,927,595 (GRCm39)	missense	probably benign	0.03
R6147:Efcab3	UTSW	11	104,858,566 (GRCm39)	missense	unknown
R6176:Efcab3	UTSW	11	104,683,383 (GRCm39)	missense	probably benign	0.16
R6181:Efcab3	UTSW	11	104,722,159 (GRCm39)	missense	probably benign	0.25
R6196:Efcab3	UTSW	11	104,746,386 (GRCm39)	missense	probably benign	0.07
R6245:Efcab3	UTSW	11	104,675,834 (GRCm39)	missense	probably benign	0.03
R6262:Efcab3	UTSW	11	104,784,579 (GRCm39)	missense	probably benign	0.24
R6263:Efcab3	UTSW	11	104,810,312 (GRCm39)	missense	unknown
R6277:Efcab3	UTSW	11	104,901,148 (GRCm39)	missense	possibly damaging	0.49
R6338:Efcab3	UTSW	11	104,734,034 (GRCm39)	nonsense	probably null
R6355:Efcab3	UTSW	11	104,896,511 (GRCm39)	missense	probably benign	0.29
R6356:Efcab3	UTSW	11	104,784,533 (GRCm39)	missense	probably benign	0.19
R6365:Efcab3	UTSW	11	104,815,412 (GRCm39)	missense	unknown
R6378:Efcab3	UTSW	11	104,999,620 (GRCm39)	missense	possibly damaging	0.83
R6391:Efcab3	UTSW	11	104,885,143 (GRCm39)	missense	possibly damaging	0.92
R6494:Efcab3	UTSW	11	104,990,845 (GRCm39)	missense	possibly damaging	0.93
R6556:Efcab3	UTSW	11	104,899,077 (GRCm39)	missense	probably null	0.03
R6573:Efcab3	UTSW	11	104,971,461 (GRCm39)	missense	possibly damaging	0.91
R6604:Efcab3	UTSW	11	104,589,772 (GRCm39)	nonsense	probably null
R6605:Efcab3	UTSW	11	104,890,107 (GRCm39)	splice site	probably null
R6634:Efcab3	UTSW	11	104,784,609 (GRCm39)	missense	probably benign	0.17
R6723:Efcab3	UTSW	11	105,007,906 (GRCm39)	missense	possibly damaging	0.95
R6851:Efcab3	UTSW	11	104,896,521 (GRCm39)	missense	probably benign	0.03
R6862:Efcab3	UTSW	11	104,612,284 (GRCm39)	nonsense	probably null
R6949:Efcab3	UTSW	11	104,799,896 (GRCm39)	missense	probably damaging	1.00
R6970:Efcab3	UTSW	11	104,667,182 (GRCm39)	missense	probably benign	0.03
R7014:Efcab3	UTSW	11	104,584,248 (GRCm39)	missense	probably benign	0.03
R7097:Efcab3	UTSW	11	104,899,787 (GRCm39)	missense	possibly damaging	0.68
R7122:Efcab3	UTSW	11	104,899,787 (GRCm39)	missense	possibly damaging	0.68
R7124:Efcab3	UTSW	11	104,629,100 (GRCm39)	missense	probably benign	0.17
R7146:Efcab3	UTSW	11	104,913,764 (GRCm39)	missense	probably benign	0.03
R7146:Efcab3	UTSW	11	104,858,578 (GRCm39)	missense	unknown
R7154:Efcab3	UTSW	11	104,589,966 (GRCm39)	splice site	probably null
R7175:Efcab3	UTSW	11	104,838,237 (GRCm39)	missense	unknown
R7189:Efcab3	UTSW	11	104,986,690 (GRCm39)	missense	probably benign
R7198:Efcab3	UTSW	11	104,642,711 (GRCm39)	missense	probably benign	0.15
R7211:Efcab3	UTSW	11	104,615,435 (GRCm39)	critical splice donor site	probably null
R7211:Efcab3	UTSW	11	104,601,539 (GRCm39)	missense	probably benign	0.01
R7216:Efcab3	UTSW	11	104,771,375 (GRCm39)	missense	possibly damaging	0.49
R7221:Efcab3	UTSW	11	104,791,432 (GRCm39)	missense	probably benign	0.36
R7233:Efcab3	UTSW	11	104,730,669 (GRCm39)	missense	possibly damaging	0.69
R7236:Efcab3	UTSW	11	104,790,093 (GRCm39)	missense	probably benign	0.10
R7262:Efcab3	UTSW	11	104,745,432 (GRCm39)	critical splice donor site	probably null
R7289:Efcab3	UTSW	11	104,929,184 (GRCm39)	missense	probably benign	0.24
R7323:Efcab3	UTSW	11	104,920,837 (GRCm39)	missense	probably benign	0.07
R7378:Efcab3	UTSW	11	104,605,528 (GRCm39)	missense	probably benign	0.03
R7388:Efcab3	UTSW	11	104,611,871 (GRCm39)	missense	probably damaging	0.97
R7390:Efcab3	UTSW	11	104,615,411 (GRCm39)	missense	possibly damaging	0.46
R7411:Efcab3	UTSW	11	104,890,549 (GRCm39)	missense	probably benign	0.10
R7468:Efcab3	UTSW	11	104,640,526 (GRCm39)	missense	probably benign	0.17
R7483:Efcab3	UTSW	11	105,000,112 (GRCm39)	missense	probably benign	0.39
R7497:Efcab3	UTSW	11	104,653,516 (GRCm39)	critical splice donor site	probably null
R7612:Efcab3	UTSW	11	104,999,647 (GRCm39)	missense	possibly damaging	0.80
R7620:Efcab3	UTSW	11	104,722,969 (GRCm39)	missense	possibly damaging	0.95
R7638:Efcab3	UTSW	11	104,927,625 (GRCm39)	missense	probably benign	0.03
R7661:Efcab3	UTSW	11	104,617,503 (GRCm39)	missense	probably benign	0.03
R7667:Efcab3	UTSW	11	104,642,737 (GRCm39)	missense	possibly damaging	0.53
R7682:Efcab3	UTSW	11	104,855,174 (GRCm39)	splice site	probably null
R7708:Efcab3	UTSW	11	104,855,397 (GRCm39)	missense	unknown
R7719:Efcab3	UTSW	11	105,002,674 (GRCm39)	missense	probably benign	0.14
R7721:Efcab3	UTSW	11	104,615,366 (GRCm39)	nonsense	probably null
R7735:Efcab3	UTSW	11	104,962,465 (GRCm39)	missense	probably benign
R7747:Efcab3	UTSW	11	104,733,429 (GRCm39)	missense	probably damaging	0.96
R7840:Efcab3	UTSW	11	104,624,539 (GRCm39)	missense	probably benign	0.07
R7846:Efcab3	UTSW	11	104,605,571 (GRCm39)	critical splice donor site	probably null
R7893:Efcab3	UTSW	11	104,870,186 (GRCm39)	missense	unknown
R7895:Efcab3	UTSW	11	105,008,150 (GRCm39)	missense	probably benign	0.29
R7897:Efcab3	UTSW	11	104,889,061 (GRCm39)	missense	probably benign	0.24
R7936:Efcab3	UTSW	11	104,890,524 (GRCm39)	missense	possibly damaging	0.89
R7936:Efcab3	UTSW	11	104,937,385 (GRCm39)	critical splice donor site	probably null
R7959:Efcab3	UTSW	11	104,933,627 (GRCm39)	missense	probably damaging	0.96
R8031:Efcab3	UTSW	11	104,772,295 (GRCm39)	missense	possibly damaging	0.49
R8041:Efcab3	UTSW	11	104,810,305 (GRCm39)	missense	unknown
R8054:Efcab3	UTSW	11	104,621,226 (GRCm39)	missense	probably benign	0.07
R8056:Efcab3	UTSW	11	104,799,896 (GRCm39)	missense	probably damaging	0.98
R8061:Efcab3	UTSW	11	104,997,275 (GRCm39)	missense	probably benign	0.00
R8088:Efcab3	UTSW	11	104,889,072 (GRCm39)	missense	probably benign	0.10
R8112:Efcab3	UTSW	11	104,841,026 (GRCm39)	missense	unknown
R8116:Efcab3	UTSW	11	105,002,677 (GRCm39)	missense	possibly damaging	0.65
R8340:Efcab3	UTSW	11	104,876,856 (GRCm39)	missense	unknown
R8405:Efcab3	UTSW	11	104,612,024 (GRCm39)	missense	probably benign	0.02
R8413:Efcab3	UTSW	11	104,811,135 (GRCm39)	missense	unknown
R8472:Efcab3	UTSW	11	104,709,463 (GRCm39)	missense	probably benign	0.07
R8549:Efcab3	UTSW	11	104,890,521 (GRCm39)	missense	probably damaging	0.99
R8699:Efcab3	UTSW	11	104,672,072 (GRCm39)	missense	probably benign	0.03
R8711:Efcab3	UTSW	11	104,743,371 (GRCm39)	missense	probably benign	0.03
R8732:Efcab3	UTSW	11	104,695,100 (GRCm39)	missense	probably benign	0.03
R8745:Efcab3	UTSW	11	104,749,304 (GRCm39)	missense	possibly damaging	0.57
R8806:Efcab3	UTSW	11	104,928,695 (GRCm39)	missense	probably benign	0.07
R8810:Efcab3	UTSW	11	104,805,721 (GRCm39)	missense	unknown
R8845:Efcab3	UTSW	11	104,899,787 (GRCm39)	missense	possibly damaging	0.68
R8870:Efcab3	UTSW	11	104,791,500 (GRCm39)	missense	probably benign	0.07
R8872:Efcab3	UTSW	11	104,760,880 (GRCm39)	missense	probably benign	0.19
R8879:Efcab3	UTSW	11	104,581,781 (GRCm39)	missense	probably benign	0.03
R8924:Efcab3	UTSW	11	104,806,253 (GRCm39)	frame shift	probably null
R8954:Efcab3	UTSW	11	104,909,525 (GRCm39)	critical splice donor site	probably null
R8960:Efcab3	UTSW	11	104,820,772 (GRCm39)	splice site	probably benign
R8975:Efcab3	UTSW	11	104,954,415 (GRCm39)	missense	probably benign	0.17
R8988:Efcab3	UTSW	11	104,911,352 (GRCm39)	missense	probably benign	0.07
R8998:Efcab3	UTSW	11	104,640,477 (GRCm39)	missense	probably benign	0.09
R8999:Efcab3	UTSW	11	104,640,477 (GRCm39)	missense	probably benign	0.09
R9002:Efcab3	UTSW	11	104,920,822 (GRCm39)	missense	probably damaging	0.99
R9012:Efcab3	UTSW	11	104,711,347 (GRCm39)	critical splice donor site	probably null
R9036:Efcab3	UTSW	11	104,927,601 (GRCm39)	missense	probably benign	0.03
R9037:Efcab3	UTSW	11	104,803,791 (GRCm39)	missense	unknown
R9059:Efcab3	UTSW	11	104,642,689 (GRCm39)	missense	possibly damaging	0.73
R9066:Efcab3	UTSW	11	104,631,688 (GRCm39)	intron	probably benign
R9122:Efcab3	UTSW	11	104,856,605 (GRCm39)	missense	unknown
R9125:Efcab3	UTSW	11	104,736,360 (GRCm39)	missense	probably damaging	1.00
R9127:Efcab3	UTSW	11	104,741,407 (GRCm39)	missense	probably benign	0.07
R9171:Efcab3	UTSW	11	104,800,708 (GRCm39)	missense	probably benign	0.36
R9219:Efcab3	UTSW	11	104,836,691 (GRCm39)	missense	unknown
R9224:Efcab3	UTSW	11	104,661,801 (GRCm39)	missense	probably benign	0.07
R9235:Efcab3	UTSW	11	104,907,987 (GRCm39)	missense	probably benign	0.19
R9294:Efcab3	UTSW	11	104,722,126 (GRCm39)	missense	probably benign	0.24
R9318:Efcab3	UTSW	11	104,856,648 (GRCm39)	critical splice donor site	probably null
R9322:Efcab3	UTSW	11	104,765,199 (GRCm39)	missense	probably benign	0.36
R9361:Efcab3	UTSW	11	104,896,524 (GRCm39)	missense	probably benign	0.03
R9408:Efcab3	UTSW	11	104,621,255 (GRCm39)	critical splice donor site	probably null
R9434:Efcab3	UTSW	11	104,899,863 (GRCm39)	missense	probably benign	0.24
R9477:Efcab3	UTSW	11	104,836,698 (GRCm39)	missense	unknown
R9658:Efcab3	UTSW	11	104,611,120 (GRCm39)	missense	probably benign	0.03
R9719:Efcab3	UTSW	11	104,867,912 (GRCm39)	missense	unknown
R9751:Efcab3	UTSW	11	104,783,911 (GRCm39)	missense	probably benign	0.19
R9763:Efcab3	UTSW	11	104,890,485 (GRCm39)	missense	possibly damaging	0.89
X0026:Efcab3	UTSW	11	105,007,937 (GRCm39)	missense	probably benign	0.03
X0026:Efcab3	UTSW	11	104,611,801 (GRCm39)	missense	probably benign	0.07
Z1088:Efcab3	UTSW	11	104,642,728 (GRCm39)	missense	probably damaging	0.96
Z1176:Efcab3	UTSW	11	104,990,872 (GRCm39)	missense	probably damaging	1.00
Z1176:Efcab3	UTSW	11	104,892,793 (GRCm39)	missense	probably benign	0.29
Z1176:Efcab3	UTSW	11	104,999,598 (GRCm39)	nonsense	probably null
Z1177:Efcab3	UTSW	11	104,711,344 (GRCm39)	missense	probably benign	0.03
Z1177:Efcab3	UTSW	11	104,630,164 (GRCm39)	nonsense	probably null
Z1177:Efcab3	UTSW	11	104,814,845 (GRCm39)	missense	unknown

Predicted Primers

PCR Primer
(F):5'- GGTTATGTGACCTCTCCTAGTC -3'
(R):5'- AAGGGAGAGCTATTTCTTGTACG -3'

Sequencing Primer
(F):5'- TGAGACAGTCTTACTCCATAGCC -3'
(R):5'- GGGAGAGCTATTTCTTGTACGTATAG -3'

Posted On

2019-06-07