Incidental Mutation 'IGL01580:Oog4'
| ID |
91359 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Oog4
|
| Ensembl Gene |
ENSMUSG00000047799 |
| Gene Name |
oogenesin 4 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.095)
|
| Stock # |
IGL01580
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
4 |
| Chromosomal Location |
143163734-143176894 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 143165682 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Serine
at position 155
(N155S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000073325
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000061277]
[ENSMUST00000073641]
|
| AlphaFold |
Q4G0C7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000061277
AA Change: N83S
PolyPhen 2
Score 0.161 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000052217
Gene: ENSMUSG00000047799
AA Change: N83S
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1a4ya_
|
195 |
357 |
6e-7 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000073641
AA Change: N155S
PolyPhen 2
Score 0.268 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000073325
Gene: ENSMUSG00000047799
AA Change: N155S
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1a4ya_
|
267 |
429 |
3e-7 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 19 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
G |
A |
11: 9,243,527 (GRCm39) |
V1797I |
probably benign |
Het |
| Abi3bp |
A |
G |
16: 56,495,573 (GRCm39) |
E865G |
probably damaging |
Het |
| Ahnak |
A |
G |
19: 8,980,203 (GRCm39) |
T496A |
probably benign |
Het |
| BC030500 |
T |
C |
8: 59,366,054 (GRCm39) |
|
probably benign |
Het |
| Col6a4 |
A |
C |
9: 105,945,397 (GRCm39) |
Y906D |
probably damaging |
Het |
| Dip2c |
T |
G |
13: 9,687,124 (GRCm39) |
|
probably null |
Het |
| Frem2 |
A |
G |
3: 53,562,596 (GRCm39) |
I637T |
probably damaging |
Het |
| Guf1 |
T |
C |
5: 69,722,764 (GRCm39) |
|
probably benign |
Het |
| Htr1f |
G |
A |
16: 64,746,198 (GRCm39) |
R365* |
probably null |
Het |
| Or10ag2 |
A |
T |
2: 87,248,880 (GRCm39) |
I163F |
probably benign |
Het |
| Or52x1 |
T |
C |
7: 104,853,113 (GRCm39) |
I146V |
probably benign |
Het |
| Phactr3 |
C |
A |
2: 177,911,297 (GRCm39) |
|
probably benign |
Het |
| Pi4k2b |
T |
C |
5: 52,912,003 (GRCm39) |
V300A |
possibly damaging |
Het |
| Pik3c2g |
A |
G |
6: 139,599,514 (GRCm39) |
D210G |
probably damaging |
Het |
| Pxdn |
A |
G |
12: 30,034,492 (GRCm39) |
T182A |
probably benign |
Het |
| Scn10a |
A |
G |
9: 119,456,225 (GRCm39) |
V1199A |
probably damaging |
Het |
| Scrn2 |
A |
G |
11: 96,922,956 (GRCm39) |
H133R |
probably benign |
Het |
| Shq1 |
G |
A |
6: 100,550,705 (GRCm39) |
S411L |
possibly damaging |
Het |
| Tmcc1 |
A |
C |
6: 116,019,946 (GRCm39) |
V462G |
possibly damaging |
Het |
|
| Other mutations in Oog4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02207:Oog4
|
APN |
4 |
143,165,510 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0038:Oog4
|
UTSW |
4 |
143,165,514 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0038:Oog4
|
UTSW |
4 |
143,165,514 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0326:Oog4
|
UTSW |
4 |
143,165,773 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0372:Oog4
|
UTSW |
4 |
143,164,259 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1056:Oog4
|
UTSW |
4 |
143,164,581 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R1598:Oog4
|
UTSW |
4 |
143,164,571 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1712:Oog4
|
UTSW |
4 |
143,166,484 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4028:Oog4
|
UTSW |
4 |
143,166,770 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4029:Oog4
|
UTSW |
4 |
143,166,770 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4030:Oog4
|
UTSW |
4 |
143,166,770 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4705:Oog4
|
UTSW |
4 |
143,165,445 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5260:Oog4
|
UTSW |
4 |
143,164,424 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5945:Oog4
|
UTSW |
4 |
143,164,293 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6499:Oog4
|
UTSW |
4 |
143,164,548 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6614:Oog4
|
UTSW |
4 |
143,164,445 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6852:Oog4
|
UTSW |
4 |
143,165,679 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7371:Oog4
|
UTSW |
4 |
143,165,346 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R7375:Oog4
|
UTSW |
4 |
143,165,544 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7501:Oog4
|
UTSW |
4 |
143,164,022 (GRCm39) |
frame shift |
probably null |
|
|
R7564:Oog4
|
UTSW |
4 |
143,164,022 (GRCm39) |
frame shift |
probably null |
|
|
R7678:Oog4
|
UTSW |
4 |
143,164,022 (GRCm39) |
frame shift |
probably null |
|
|
R7688:Oog4
|
UTSW |
4 |
143,164,022 (GRCm39) |
frame shift |
probably null |
|
|
R7689:Oog4
|
UTSW |
4 |
143,164,022 (GRCm39) |
frame shift |
probably null |
|
|
R8219:Oog4
|
UTSW |
4 |
143,166,508 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8274:Oog4
|
UTSW |
4 |
143,166,459 (GRCm39) |
splice site |
probably benign |
|
|
R8352:Oog4
|
UTSW |
4 |
143,164,047 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8452:Oog4
|
UTSW |
4 |
143,164,047 (GRCm39) |
missense |
probably benign |
0.22 |
|
Z1177:Oog4
|
UTSW |
4 |
143,164,145 (GRCm39) |
missense |
probably benign |
0.06 |
|
Z1177:Oog4
|
UTSW |
4 |
143,164,144 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
| Posted On |
2013-12-09 |
Incidental Mutation