Incidental Mutation 'IGL01677:Ubfd1'
ID103689
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Ubfd1
Ensembl Gene ENSMUSG00000030870
Gene Nameubiquitin family domain containing 1
SynonymsD7Wsu128e, D7Wsu105e
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.140) question?
Stock #IGL01677
Quality Score
Status
Chromosome7
Chromosomal Location122067175-122082194 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to A at 122071699 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s): [ENSMUST00000033158] [ENSMUST00000033159]
Predicted Effect probably benign
Transcript: ENSMUST00000033158
SMART Domains Protein: ENSMUSP00000033158
Gene: ENSMUSG00000030870

DomainStartEndE-ValueType
low complexity region 3 15 N/A INTRINSIC
low complexity region 76 87 N/A INTRINSIC
low complexity region 93 104 N/A INTRINSIC
low complexity region 114 128 N/A INTRINSIC
UBQ 145 214 8.34e-16 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000033159
SMART Domains Protein: ENSMUSP00000033159
Gene: ENSMUSG00000030871

DomainStartEndE-ValueType
Pfam:tRNA-synt_1c 36 353 3.5e-88 PFAM
low complexity region 448 460 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000124733
Predicted Effect noncoding transcript
Transcript: ENSMUST00000133390
Predicted Effect noncoding transcript
Transcript: ENSMUST00000147397
Predicted Effect noncoding transcript
Transcript: ENSMUST00000148060
Predicted Effect noncoding transcript
Transcript: ENSMUST00000151530
Predicted Effect probably benign
Transcript: ENSMUST00000153640
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 33 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Arap3 T A 18: 37,996,647 M154L probably benign Het
Asph T C 4: 9,607,853 D131G probably damaging Het
Cdc45 G A 16: 18,787,000 T429I probably benign Het
Cnga3 C T 1: 37,244,918 R101* probably null Het
Cp T C 3: 19,966,434 I197T probably damaging Het
Cyp4b1 T C 4: 115,636,282 D77G probably damaging Het
Dnah5 G T 15: 28,367,782 W2771L probably damaging Het
Fas G A 19: 34,318,818 V177I probably benign Het
Gde1 A G 7: 118,694,487 probably benign Het
Hyou1 T C 9: 44,382,012 S223P probably benign Het
Klre1 G T 6: 129,582,043 G75C probably damaging Het
Lama1 T C 17: 67,779,148 C1461R probably benign Het
Map3k7 T C 4: 32,017,158 probably benign Het
Mrpl18 A T 17: 12,911,688 I178N probably damaging Het
Nckap1 T C 2: 80,530,297 T503A probably benign Het
Olfr134 T C 17: 38,175,875 S264P probably damaging Het
Olfr654 T C 7: 104,588,145 S114P probably damaging Het
Olfr669 T C 7: 104,938,645 S40P probably benign Het
Olfr846 T C 9: 19,361,145 D70G probably damaging Het
Orc1 C T 4: 108,604,585 T593I probably damaging Het
Phtf1 T A 3: 103,998,783 S594T probably damaging Het
Ppp1r13b A T 12: 111,843,665 D78E probably benign Het
Proz T C 8: 13,065,238 probably benign Het
Rtcb C A 10: 85,943,929 Q292H probably damaging Het
Sept11 A T 5: 93,148,533 T95S probably damaging Het
Slc12a1 A G 2: 125,178,149 probably benign Het
Slc45a3 T A 1: 131,978,970 I394N probably damaging Het
Slc8a1 T C 17: 81,648,607 H334R probably damaging Het
Sort1 T C 3: 108,344,885 I466T probably benign Het
Susd2 A T 10: 75,639,431 V515E possibly damaging Het
Ttll3 A G 6: 113,412,984 R778G probably benign Het
Utrn G A 10: 12,744,157 T248M probably damaging Het
Vmn2r11 T G 5: 109,053,957 D227A possibly damaging Het
Other mutations in Ubfd1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01011:Ubfd1 APN 7 122078472 missense probably benign 0.04
R0883:Ubfd1 UTSW 7 122067491 unclassified probably benign
R2364:Ubfd1 UTSW 7 122068944 missense probably benign 0.00
R3879:Ubfd1 UTSW 7 122068776 unclassified probably benign
R3880:Ubfd1 UTSW 7 122068776 unclassified probably benign
R3972:Ubfd1 UTSW 7 122067433 missense probably benign
R4241:Ubfd1 UTSW 7 122071754 missense possibly damaging 0.56
R5120:Ubfd1 UTSW 7 122071750 missense probably damaging 1.00
R5276:Ubfd1 UTSW 7 122068868 missense probably damaging 1.00
R6793:Ubfd1 UTSW 7 122067880 missense probably benign
R7493:Ubfd1 UTSW 7 122067412 missense probably benign 0.10
R7619:Ubfd1 UTSW 7 122067383 missense probably benign 0.00
Posted On2014-01-21