Incidental Mutation 'IGL01710:Gstt2'
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gstt2
Ensembl Gene ENSMUSG00000033318
Gene Nameglutathione S-transferase, theta 2
SynonymsYrs, mGSTT2
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01710
Quality Score
Chromosomal Location75831114-75837424 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 75833745 bp
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000151239 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000038257] [ENSMUST00000218500] [ENSMUST00000220195] [ENSMUST00000220440]
Predicted Effect probably benign
Transcript: ENSMUST00000038257
SMART Domains Protein: ENSMUSP00000046324
Gene: ENSMUSG00000033318

Pfam:GST_N 1 76 4.6e-12 PFAM
Pfam:GST_N_3 5 84 1.4e-11 PFAM
Pfam:GST_N_2 11 77 3.5e-10 PFAM
Pfam:GST_C 73 199 1.5e-10 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000218034
Predicted Effect probably benign
Transcript: ENSMUST00000218500
Predicted Effect noncoding transcript
Transcript: ENSMUST00000218646
Predicted Effect noncoding transcript
Transcript: ENSMUST00000218745
Predicted Effect noncoding transcript
Transcript: ENSMUST00000219343
Predicted Effect probably benign
Transcript: ENSMUST00000220195
Predicted Effect probably benign
Transcript: ENSMUST00000220440
Coding Region Coverage
Validation Efficiency
MGI Phenotype PHENOTYPE: Mice homozygous for a disruption in this gene display a normal phenotype. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 41 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ablim3 G A 18: 61,871,574 T48I probably damaging Het
Ccpg1 T C 9: 72,997,441 probably benign Het
Chkb G A 15: 89,426,640 Q379* probably null Het
Chst15 T A 7: 132,270,507 D15V probably benign Het
Cntn4 G A 6: 106,550,431 V425I possibly damaging Het
Cpa6 T A 1: 10,325,272 N390I probably damaging Het
Efhd2 A G 4: 141,860,561 F193S probably damaging Het
Ell3 T C 2: 121,441,512 H128R probably damaging Het
Ercc5 T G 1: 44,164,075 L291V probably damaging Het
Eva1c A G 16: 90,904,347 Y302C probably damaging Het
Fmo3 A C 1: 162,983,043 L26R probably damaging Het
Galntl6 T A 8: 58,535,968 D17V probably damaging Het
Gm6483 C T 8: 19,691,613 P55S probably damaging Het
Hmcn2 T A 2: 31,343,102 L221Q probably damaging Het
Hoxa3 T C 6: 52,170,574 probably benign Het
Kctd12b T C X: 153,689,483 D70G probably damaging Het
Kdm7a T A 6: 39,175,386 E125D probably benign Het
Klk1b21 T A 7: 44,106,495 F249L probably benign Het
Mrpl41 T C 2: 24,974,417 D81G possibly damaging Het
Nomo1 T A 7: 46,038,556 L82Q probably damaging Het
Olfr482 G T 7: 108,095,242 F109L probably benign Het
Papolg A T 11: 23,864,026 S718T probably damaging Het
Pex6 A G 17: 46,725,326 probably benign Het
Pi4k2a T A 19: 42,104,979 L253Q probably damaging Het
Prdx6b T A 2: 80,293,146 F100I probably damaging Het
Prr36 G A 8: 4,215,243 P169L probably damaging Het
Ptgfrn T C 3: 101,073,088 E312G probably damaging Het
Rasgrf1 A G 9: 89,991,692 I685V probably benign Het
Setdb1 T C 3: 95,338,853 E586G probably damaging Het
Sez6l2 C A 7: 126,968,216 T841K probably damaging Het
Slc25a17 A T 15: 81,327,326 L163* probably null Het
Slc35f3 A T 8: 126,389,161 I276F probably benign Het
Tcerg1l T A 7: 138,395,060 K149N possibly damaging Het
Tex28 T A X: 74,152,333 K278* probably null Het
Tmprss9 A G 10: 80,897,959 probably benign Het
Tnfaip8l1 A G 17: 56,171,782 K24R probably benign Het
Trim36 T C 18: 46,188,388 probably benign Het
Uba1 C T X: 20,671,365 T274I possibly damaging Het
Ubr2 T C 17: 46,943,409 T1439A probably benign Het
Ubr4 A G 4: 139,418,461 D1523G possibly damaging Het
Uchl4 A T 9: 64,235,506 T90S probably benign Het
Other mutations in Gstt2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01571:Gstt2 APN 10 75834171 splice site probably benign
IGL02642:Gstt2 APN 10 75832818 missense probably benign 0.17
IGL03375:Gstt2 APN 10 75832821 splice site probably null
R0389:Gstt2 UTSW 10 75832432 missense probably damaging 1.00
R1751:Gstt2 UTSW 10 75834264 missense probably damaging 1.00
R1767:Gstt2 UTSW 10 75834264 missense probably damaging 1.00
R1971:Gstt2 UTSW 10 75832665 missense probably benign 0.10
R2367:Gstt2 UTSW 10 75832690 missense probably benign 0.44
R5027:Gstt2 UTSW 10 75831892 missense probably damaging 0.99
R7457:Gstt2 UTSW 10 75832520 missense probably damaging 1.00
R7579:Gstt2 UTSW 10 75834185 missense probably benign 0.00
R7910:Gstt2 UTSW 10 75831902 missense probably benign 0.25
R7912:Gstt2 UTSW 10 75832584 missense probably benign 0.27
R7991:Gstt2 UTSW 10 75831902 missense probably benign 0.25
R7993:Gstt2 UTSW 10 75832584 missense probably benign 0.27
Posted On2014-01-21