Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00092:Cd300c2'

28450

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Cd300c2

Ensembl Gene

ENSMUSG00000044811

Gene Name

CD300C molecule 2

Synonyms

MAIR-II, Cd300d, Igsf7, LMIR2, DIgR1, AF251705, Clm4

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL00092

Quality Score

Status

Chromosome

Chromosomal Location

114887595-114892706 bp(-) (GRCm39)

Type of Mutation

utr 5 prime

DNA Base Change (assembly)

T to C at 114892375 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000124035 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092464] [ENSMUST00000141188]

AlphaFold

Q7TSN2

Predicted Effect

probably benign
Transcript: ENSMUST00000092464

SMART Domains

Protein: ENSMUSP00000090121
Gene: ENSMUSG00000044811

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC
IG	28	134	1.52e-3	SMART
transmembrane domain	187	209	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000141188

SMART Domains

Protein: ENSMUSP00000124035
Gene: ENSMUSG00000044811

Domain	Start	End	E-Value	Type
signal peptide	1	24	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased stimulated B cell proliferation. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 43 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcb5	T	C	12: 118,892,430 (GRCm39)	D443G	probably benign	Het
Atg16l1	T	C	1: 87,693,119 (GRCm39)	I28T	possibly damaging	Het
Bpi	T	A	2: 158,116,716 (GRCm39)	V371E	probably damaging	Het
Cd109	T	G	9: 78,524,251 (GRCm39)	V55G	probably damaging	Het
Cic	C	T	7: 24,991,549 (GRCm39)	R1280C	probably damaging	Het
Cngb1	G	A	8: 95,968,812 (GRCm39)		probably benign	Het
Cntn4	G	T	6: 106,483,186 (GRCm39)	C247F	probably damaging	Het
Disp3	C	T	4: 148,325,991 (GRCm39)	V1256I	probably benign	Het
Farsb	A	T	1: 78,439,630 (GRCm39)	S338T	probably benign	Het
Fcnb	T	C	2: 27,966,813 (GRCm39)	N240S	probably benign	Het
Flg2	A	G	3: 93,127,162 (GRCm39)	S5G	possibly damaging	Het
Git1	T	C	11: 77,396,783 (GRCm39)	L635P	probably benign	Het
Gm21985	T	G	2: 112,181,679 (GRCm39)	W685G	probably damaging	Het
Gpt2	T	C	8: 86,238,953 (GRCm39)	V262A	probably benign	Het
Hecw2	A	G	1: 53,869,896 (GRCm39)	V1444A	probably damaging	Het
Herc1	T	C	9: 66,391,248 (GRCm39)	V4017A	probably benign	Het
Klhl17	T	C	4: 156,318,147 (GRCm39)	T129A	possibly damaging	Het
Krt84	T	G	15: 101,437,170 (GRCm39)	D331A	probably damaging	Het
Lrrc9	C	T	12: 72,533,017 (GRCm39)	T963M	possibly damaging	Het
Mtcl1	C	T	17: 66,651,314 (GRCm39)	V935I	probably benign	Het
Muc4	G	A	16: 32,754,086 (GRCm38)	G1321R	probably benign	Het
Myocd	T	C	11: 65,071,770 (GRCm39)		probably null	Het
Nid1	A	G	13: 13,650,977 (GRCm39)	N505D	probably damaging	Het
Ninj1	A	T	13: 49,347,210 (GRCm39)		probably null	Het
Or14a260	C	T	7: 85,985,269 (GRCm39)	V112I	probably benign	Het
Or1x6	C	A	11: 50,939,227 (GRCm39)	Q98K	probably benign	Het
Or4d10c	A	T	19: 12,065,357 (GRCm39)	D266E	probably benign	Het
Plscr2	T	A	9: 92,172,685 (GRCm39)		probably benign	Het
Ppfia2	A	G	10: 106,655,353 (GRCm39)	T307A	probably benign	Het
Sart3	T	C	5: 113,884,730 (GRCm39)	R625G	probably benign	Het
Sohlh2	T	A	3: 55,115,236 (GRCm39)	L407H	probably damaging	Het
Sorcs1	A	G	19: 50,178,492 (GRCm39)	S877P	probably damaging	Het
Stat1	T	C	1: 52,161,754 (GRCm39)	M1T	probably null	Het
Szt2	C	T	4: 118,241,447 (GRCm39)		probably benign	Het
Tars3	G	T	7: 65,302,007 (GRCm39)		probably null	Het
Terb2	T	A	2: 122,028,867 (GRCm39)	S141R	probably benign	Het
Tgfbrap1	T	C	1: 43,099,283 (GRCm39)	Y177C	probably damaging	Het
Trappc9	A	T	15: 72,897,875 (GRCm39)	I169N	possibly damaging	Het
Trim47	A	G	11: 115,997,020 (GRCm39)	L578P	probably damaging	Het
Usp34	G	A	11: 23,386,020 (GRCm39)	R2149H	probably damaging	Het
Vmn2r90	T	C	17: 17,953,758 (GRCm39)	S641P	probably benign	Het
Vwa5a	T	A	9: 38,649,110 (GRCm39)		probably null	Het
Zzef1	T	A	11: 72,765,952 (GRCm39)	I1493N	probably benign	Het

Other mutations in Cd300c2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02695:Cd300c2	APN	11	114,892,379 (GRCm39)	utr 5 prime	probably benign
IGL03086:Cd300c2	APN	11	114,891,649 (GRCm39)	missense	possibly damaging	0.76
R1933:Cd300c2	UTSW	11	114,891,685 (GRCm39)	missense	probably benign	0.22
R4707:Cd300c2	UTSW	11	114,887,811 (GRCm39)	missense	probably benign	0.03
R4866:Cd300c2	UTSW	11	114,891,807 (GRCm39)	nonsense	probably null
R4900:Cd300c2	UTSW	11	114,891,807 (GRCm39)	nonsense	probably null
R4906:Cd300c2	UTSW	11	114,887,826 (GRCm39)	missense	possibly damaging	0.85
R4908:Cd300c2	UTSW	11	114,887,772 (GRCm39)	missense	probably damaging	0.97
R4946:Cd300c2	UTSW	11	114,887,731 (GRCm39)	missense	probably benign	0.04
R5568:Cd300c2	UTSW	11	114,891,662 (GRCm39)	missense	probably damaging	1.00
R6870:Cd300c2	UTSW	11	114,891,503 (GRCm39)	missense	probably damaging	0.99
R7474:Cd300c2	UTSW	11	114,889,122 (GRCm39)	missense	probably benign	0.00
R7826:Cd300c2	UTSW	11	114,891,644 (GRCm39)	missense	possibly damaging	0.77
R8210:Cd300c2	UTSW	11	114,891,634 (GRCm39)	missense	possibly damaging	0.89
R8443:Cd300c2	UTSW	11	114,891,466 (GRCm39)	missense	probably benign	0.42
R8831:Cd300c2	UTSW	11	114,891,844 (GRCm39)	nonsense	probably null
R9405:Cd300c2	UTSW	11	114,891,587 (GRCm39)	missense	probably damaging	1.00
R9762:Cd300c2	UTSW	11	114,887,775 (GRCm39)	missense	probably damaging	1.00

Posted On

2013-04-17