Incidental Mutation 'IGL02801:Zdhhc14'
ID360223
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zdhhc14
Ensembl Gene ENSMUSG00000034265
Gene Namezinc finger, DHHC domain containing 14
SynonymsNew1cp, B530001K09Rik
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.086) question?
Stock #IGL02801
Quality Score
Status
Chromosome17
Chromosomal Location5492557-5753811 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to G at 5726819 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000086589 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000089185]
Predicted Effect probably null
Transcript: ENSMUST00000089185
SMART Domains Protein: ENSMUSP00000086589
Gene: ENSMUSG00000034265

DomainStartEndE-ValueType
transmembrane domain 62 81 N/A INTRINSIC
transmembrane domain 91 110 N/A INTRINSIC
Pfam:zf-DHHC 160 289 1.8e-38 PFAM
low complexity region 351 365 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 53 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Akap5 A T 12: 76,328,995 K400N probably benign Het
Aox2 A T 1: 58,354,177 I1193F probably damaging Het
Arhgef16 A T 4: 154,291,507 L10Q probably damaging Het
Arl10 T C 13: 54,575,883 V106A probably benign Het
Bmi1 T C 2: 18,681,881 Y24H probably damaging Het
Cd163 T A 6: 124,320,529 I878K probably benign Het
Col12a1 A G 9: 79,608,414 probably null Het
Csmd2 T C 4: 128,552,075 probably null Het
Dcp2 G T 18: 44,417,711 M417I probably damaging Het
Ddx11 T A 17: 66,148,033 C662S probably benign Het
Dhx29 G A 13: 112,964,646 C1241Y probably damaging Het
Dnajc6 C T 4: 101,597,813 P37L probably benign Het
Dqx1 A G 6: 83,060,495 probably null Het
Dzip1 T A 14: 118,885,655 K643* probably null Het
Ecel1 A G 1: 87,152,003 S463P probably damaging Het
Eml5 A G 12: 98,817,845 V1361A possibly damaging Het
Fads2 C A 19: 10,082,645 A222S possibly damaging Het
Fancd2 A G 6: 113,593,317 N1410D probably benign Het
Fbxw16 A G 9: 109,441,076 F199S possibly damaging Het
Frem2 A G 3: 53,652,175 V1637A possibly damaging Het
Gabrg2 A G 11: 41,912,393 S442P probably damaging Het
Gprin3 T C 6: 59,354,981 T114A possibly damaging Het
Hoxd8 A G 2: 74,706,568 E27G probably damaging Het
Isl2 A G 9: 55,545,532 probably null Het
Lamc2 T A 1: 153,136,783 H715L probably benign Het
Lrif1 T C 3: 106,734,614 V102A possibly damaging Het
Lrrc39 A G 3: 116,578,346 N254S possibly damaging Het
Med13l T C 5: 118,745,113 W1346R probably damaging Het
Melk T C 4: 44,360,930 I570T probably damaging Het
Mlkl G A 8: 111,316,432 T361M probably benign Het
Myo1f T A 17: 33,578,137 M94K probably damaging Het
Naip1 A G 13: 100,444,368 C124R probably damaging Het
Nek1 G A 8: 61,121,061 probably null Het
Nrn1 C A 13: 36,730,106 probably null Het
Pde1c G T 6: 56,173,666 N289K probably damaging Het
Pfas G A 11: 68,988,277 probably benign Het
Pms2 A T 5: 143,925,835 I587F probably benign Het
Ppargc1b T C 18: 61,307,684 E721G possibly damaging Het
Ppp2r1b A G 9: 50,878,827 I435V probably benign Het
Psip1 C T 4: 83,458,120 S494N probably benign Het
Ranbp3 T C 17: 56,710,766 V474A probably benign Het
Rnf220 C T 4: 117,273,251 C259Y probably damaging Het
Sdr16c6 T C 4: 4,076,603 I99V probably benign Het
Slc36a1 A T 11: 55,226,053 I303F probably benign Het
Slc4a1 C T 11: 102,359,146 probably null Het
Syncrip A T 9: 88,479,809 D84E probably damaging Het
Tbc1d9b T C 11: 50,152,830 Y593H probably damaging Het
Tenm2 G T 11: 36,047,030 Y1605* probably null Het
Tmem135 T A 7: 89,154,125 H280L probably benign Het
Tmem229a T A 6: 24,955,122 Q211L probably benign Het
Txlna T C 4: 129,640,408 D5G probably damaging Het
Vmn2r57 T C 7: 41,448,632 I4V probably benign Het
Wdfy3 A G 5: 101,907,587 L1539S probably damaging Het
Other mutations in Zdhhc14
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00419:Zdhhc14 APN 17 5752684 splice site probably benign
IGL00909:Zdhhc14 APN 17 5752792 missense probably benign
IGL00964:Zdhhc14 APN 17 5712481 missense probably damaging 1.00
IGL01398:Zdhhc14 APN 17 5712463 missense possibly damaging 0.90
IGL01483:Zdhhc14 APN 17 5712458 missense probably benign 0.01
IGL02185:Zdhhc14 APN 17 5752882 missense probably benign 0.01
R0189:Zdhhc14 UTSW 17 5725264 missense possibly damaging 0.90
R0304:Zdhhc14 UTSW 17 5725336 splice site probably benign
R0648:Zdhhc14 UTSW 17 5493602 missense probably benign 0.01
R1017:Zdhhc14 UTSW 17 5493649 missense probably damaging 0.99
R1595:Zdhhc14 UTSW 17 5493556 missense probably benign 0.00
R2416:Zdhhc14 UTSW 17 5753008 missense probably benign
R3420:Zdhhc14 UTSW 17 5753091 makesense probably null
R3421:Zdhhc14 UTSW 17 5753091 makesense probably null
R4063:Zdhhc14 UTSW 17 5752708 missense probably damaging 1.00
R4088:Zdhhc14 UTSW 17 5726856 missense probably benign 0.01
R5359:Zdhhc14 UTSW 17 5493546 missense probably benign
R6236:Zdhhc14 UTSW 17 5493643 missense probably damaging 1.00
R7029:Zdhhc14 UTSW 17 5647911 missense probably damaging 0.97
R7350:Zdhhc14 UTSW 17 5726876 missense probably benign 0.44
R7873:Zdhhc14 UTSW 17 5712454 missense probably benign 0.37
R8247:Zdhhc14 UTSW 17 5685756 missense probably damaging 1.00
R8492:Zdhhc14 UTSW 17 5712414 missense probably damaging 0.98
R8865:Zdhhc14 UTSW 17 5725295 missense possibly damaging 0.58
Posted On2015-12-18