Incidental Mutation 'IGL03229:Prl2c1'
ID413837
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Prl2c1
Ensembl Gene ENSMUSG00000062551
Gene NameProlactin family 2, subfamily c, member 1
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.067) question?
Stock #IGL03229
Quality Score
Status
Chromosome13
Chromosomal Location27849342-27857788 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to A at 27856629 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000105964 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000054932] [ENSMUST00000110335]
Predicted Effect probably benign
Transcript: ENSMUST00000054932
SMART Domains Protein: ENSMUSP00000053446
Gene: ENSMUSG00000062551

DomainStartEndE-ValueType
Pfam:Hormone_1 16 226 1.8e-73 PFAM
Predicted Effect
SMART Domains Protein: ENSMUSP00000078221
Gene: ENSMUSG00000062551

DomainStartEndE-ValueType
Pfam:Hormone_1 16 72 7.1e-14 PFAM
Pfam:Hormone_1 70 192 4.1e-41 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000110335
SMART Domains Protein: ENSMUSP00000105964
Gene: ENSMUSG00000062551

DomainStartEndE-ValueType
Pfam:Hormone_1 16 228 1.9e-77 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 36 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abcb4 T C 5: 8,940,936 I832T probably damaging Het
Adcyap1r1 T C 6: 55,478,123 S124P probably damaging Het
Coq4 A G 2: 29,788,485 D41G probably benign Het
Cpb1 A T 3: 20,249,837 Y354* probably null Het
Dip2b T C 15: 100,207,838 probably benign Het
Dmxl2 C T 9: 54,404,172 R1755H probably damaging Het
Dyrk4 G T 6: 126,886,642 probably benign Het
E2f7 T C 10: 110,754,346 V120A probably benign Het
Fsip2 A T 2: 82,978,076 I1580F possibly damaging Het
Gm7030 C T 17: 36,127,722 G259E probably damaging Het
Gm9755 C A 8: 67,514,672 noncoding transcript Het
Gprc6a T G 10: 51,616,603 N480T probably damaging Het
Hdlbp T C 1: 93,430,187 I331V probably benign Het
Heatr6 G T 11: 83,781,445 G1093V probably benign Het
Hist2h2ac C T 3: 96,220,637 A70T probably damaging Het
Kri1 T C 9: 21,282,070 E162G probably damaging Het
Nckipsd T C 9: 108,811,614 V116A probably benign Het
Nek10 A G 14: 14,986,686 H997R probably benign Het
Nov A G 15: 54,749,308 T238A probably benign Het
Nxph1 A G 6: 9,247,830 Y267C probably damaging Het
Olfr1090 A T 2: 86,754,016 C241S probably damaging Het
Olfr294 T C 7: 86,616,078 D189G probably benign Het
Ppip5k2 A T 1: 97,728,961 V829E probably damaging Het
Prkcz A C 4: 155,262,506 S573A probably benign Het
Rgs22 T A 15: 36,015,779 probably benign Het
Scn1a T A 2: 66,299,713 I1253F probably damaging Het
Tarm1 A G 7: 3,496,897 C146R probably damaging Het
Tor2a A T 2: 32,759,692 I189F probably damaging Het
Trappc9 A T 15: 73,058,456 L17Q probably damaging Het
Trim45 T A 3: 100,923,069 L53Q probably damaging Het
Ubr7 T C 12: 102,769,155 L291P probably damaging Het
Unc79 T C 12: 103,134,539 V1878A probably damaging Het
Wdr90 T C 17: 25,845,463 probably benign Het
Xpnpep1 T C 19: 53,025,380 H42R probably benign Het
Zfp750 G A 11: 121,512,952 H366Y possibly damaging Het
Zmynd11 A G 13: 9,689,565 C462R probably damaging Het
Other mutations in Prl2c1
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL02630:Prl2c1 APN 13 27857497 splice site probably benign
IGL02648:Prl2c1 APN 13 27857559 missense probably benign 0.44
IGL02823:Prl2c1 APN 13 27856433 splice site probably benign
IGL03024:Prl2c1 APN 13 27856541 missense probably benign 0.22
R4739:Prl2c1 UTSW 13 27857678 missense probably damaging 1.00
R4978:Prl2c1 UTSW 13 27857570 missense probably benign 0.00
R6860:Prl2c1 UTSW 13 27851741 missense probably benign 0.31
R7719:Prl2c1 UTSW 13 27851797 missense probably damaging 1.00
Posted On2016-08-02