Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01060:Gm12887'

50822

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm12887

Ensembl Gene

Gene Name

predicted gene 12887

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.072) question?

Stock #

IGL01060

Quality Score

Status

Chromosome

Chromosomal Location

121614271-121622103 bp(-) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

C to T at 121616413 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000101872 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000106265]

Predicted Effect

probably benign
Transcript: ENSMUST00000106265

SMART Domains

Protein: ENSMUSP00000101872
Gene: ENSMUSG00000078575

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC
Pfam:Palm_thioest	37	119	2.4e-10	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 29 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110038F14Rik	G	A	15: 76,950,275	V124I	probably damaging	Het
Anks4b	A	G	7: 120,173,925	T3A	possibly damaging	Het
Arhgef26	T	A	3: 62,340,121	S209T	probably benign	Het
Ccdc78	A	G	17: 25,788,832	D281G	probably damaging	Het
Ccnb3	A	T	X: 6,980,274	N1362K	probably benign	Het
Dnah2	T	C	11: 69,478,092	N1662S	possibly damaging	Het
Ern2	T	A	7: 122,170,092	R904W	probably damaging	Het
Fam120c	C	T	X: 151,469,587	P1045S	probably benign	Het
Gpld1	G	A	13: 24,982,566	G627S	probably damaging	Het
Ikbkap	C	T	4: 56,784,537		probably null	Het
Krt77	T	A	15: 101,860,880		probably benign	Het
Ltf	A	T	9: 111,022,882		probably null	Het
Map3k6	G	T	4: 133,247,302		probably null	Het
Nsd1	G	A	13: 55,263,429	G1431D	probably damaging	Het
Plekhm2	C	T	4: 141,642,645		probably null	Het
Popdc2	T	A	16: 38,373,965	N249K	probably damaging	Het
Ppm1h	A	G	10: 122,907,571	D400G	possibly damaging	Het
Rps6ka1	A	T	4: 133,860,870	S320T	probably damaging	Het
Rsph6a	C	T	7: 19,054,868	R42*	probably null	Het
Sap130	T	C	18: 31,715,443	L967P	probably damaging	Het
Smyd2	T	C	1: 189,897,470	E121G	possibly damaging	Het
Sspo	G	A	6: 48,449,479	W144*	probably null	Het
Taar6	A	G	10: 23,985,072	V192A	probably benign	Het
Tbc1d24	A	T	17: 24,185,828	V114E	probably damaging	Het
Trim16	T	C	11: 62,820,704	I67T	probably benign	Het
Ttll7	A	G	3: 146,909,582	D267G	possibly damaging	Het
Ttn	T	C	2: 76,889,729		probably benign	Het
Vmn2r56	T	A	7: 12,713,089	I379F	probably damaging	Het
Zfp14	T	C	7: 30,038,085	T492A	probably damaging	Het

Other mutations in Gm12887

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02113:Gm12887	APN	4	121616495	missense	probably benign	0.32
R0055:Gm12887	UTSW	4	121616469	missense	probably damaging	0.98
R0055:Gm12887	UTSW	4	121616469	missense	probably damaging	0.98
R1673:Gm12887	UTSW	4	121616458	missense	probably damaging	0.98
R1784:Gm12887	UTSW	4	121616518	missense	probably benign	0.44
R1843:Gm12887	UTSW	4	121622030	missense	probably damaging	0.98
R4231:Gm12887	UTSW	4	121622102	start codon destroyed	probably null	0.53
R5258:Gm12887	UTSW	4	121615700	missense	probably benign
R6528:Gm12887	UTSW	4	121615637	missense	probably damaging	1.00
R8037:Gm12887	UTSW	4	121615690	missense	probably damaging	1.00
R9038:Gm12887	UTSW	4	121616419	critical splice donor site	probably null
R9073:Gm12887	UTSW	4	121622041	splice site	probably null
R9157:Gm12887	UTSW	4	121616504	missense	probably benign	0.06
R9313:Gm12887	UTSW	4	121616504	missense	probably benign	0.06

Posted On

2013-06-21