Incidental Mutation 'R2155:Cdca2'
| ID |
234747 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cdca2
|
| Ensembl Gene |
ENSMUSG00000048922 |
| Gene Name |
cell division cycle associated 2 |
| Synonyms |
2610311M19Rik |
| MMRRC Submission |
040158-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.080)
|
| Stock # |
R2155 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
14 |
| Chromosomal Location |
67913780-67953290 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 67952287 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Serine
at position 28
(L28S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000127571
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000078053]
[ENSMUST00000124045]
[ENSMUST00000125212]
[ENSMUST00000132705]
[ENSMUST00000145542]
[ENSMUST00000150006]
[ENSMUST00000150768]
[ENSMUST00000163100]
[ENSMUST00000156700]
[ENSMUST00000152243]
|
| AlphaFold |
Q14B71 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000078053
|
| SMART Domains |
Protein: ENSMUSP00000077200
Gene: ENSMUSG00000034327
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3354
|
1 |
65 |
3.5e-22 |
PFAM |
|
BTB
|
89 |
192 |
1.76e-16 |
SMART |
|
Pfam:Pentapeptide
|
253 |
292 |
1e-14 |
PFAM |
|
Pfam:Pentapeptide_4
|
258 |
334 |
2.7e-15 |
PFAM |
|
Pfam:Pentapeptide
|
288 |
327 |
6.8e-17 |
PFAM |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000124045
AA Change: L28S
PolyPhen 2
Score 0.528 (Sensitivity: 0.88; Specificity: 0.90)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000125212
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000132705
AA Change: L28S
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000115633
Gene: ENSMUSG00000048922
AA Change: L28S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PP1_bind
|
378 |
437 |
4.3e-28 |
PFAM |
|
low complexity region
|
515 |
528 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000145542
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000150006
AA Change: L28S
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000117847
Gene: ENSMUSG00000048922
AA Change: L28S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PP1_bind
|
378 |
437 |
5.4e-28 |
PFAM |
|
low complexity region
|
515 |
528 |
N/A |
INTRINSIC |
|
low complexity region
|
542 |
556 |
N/A |
INTRINSIC |
|
low complexity region
|
931 |
942 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150768
|
| SMART Domains |
Protein: ENSMUSP00000114489
Gene: ENSMUSG00000034327
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:KHA
|
2 |
64 |
1.4e-21 |
PFAM |
|
BTB
|
89 |
192 |
1.76e-16 |
SMART |
|
Pfam:Pentapeptide
|
219 |
255 |
9.3e-8 |
PFAM |
|
Pfam:Pentapeptide
|
248 |
280 |
9.3e-11 |
PFAM |
|
Pfam:Pentapeptide
|
258 |
297 |
3e-10 |
PFAM |
|
Pfam:Pentapeptide
|
303 |
342 |
3.2e-13 |
PFAM |
|
Pfam:Pentapeptide_4
|
308 |
384 |
3.3e-13 |
PFAM |
|
Pfam:Pentapeptide
|
338 |
377 |
2.1e-15 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000163100
AA Change: L28S
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000127571
Gene: ENSMUSG00000048922
AA Change: L28S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PP1_bind
|
379 |
436 |
4.1e-27 |
PFAM |
|
low complexity region
|
515 |
528 |
N/A |
INTRINSIC |
|
low complexity region
|
542 |
556 |
N/A |
INTRINSIC |
|
low complexity region
|
931 |
942 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000155312
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000156700
|
| SMART Domains |
Protein: ENSMUSP00000115002
Gene: ENSMUSG00000034327
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:DUF3354
|
1 |
65 |
2.5e-23 |
PFAM |
|
SCOP:d3kvt__
|
89 |
107 |
9e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152243
|
| SMART Domains |
Protein: ENSMUSP00000120440
Gene: ENSMUSG00000034327
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BTB_2
|
1 |
70 |
1.3e-13 |
PFAM |
|
Pfam:BTB
|
1 |
78 |
6.2e-7 |
PFAM |
|
Pfam:Pentapeptide
|
105 |
137 |
4.3e-8 |
PFAM |
|
Pfam:Pentapeptide
|
134 |
166 |
5.5e-11 |
PFAM |
|
Pfam:Pentapeptide
|
144 |
183 |
1.5e-10 |
PFAM |
|
Pfam:Pentapeptide_4
|
165 |
239 |
5.3e-9 |
PFAM |
|
Pfam:Pentapeptide
|
189 |
228 |
1.7e-13 |
PFAM |
|
Pfam:Pentapeptide
|
209 |
237 |
9.3e-8 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.4%
- 20x: 95.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a targeting subunit of the cell-cycle associated protein, protein phosphatase 1, with a role in targeting this protein to chromatin during anaphase. These two proteins comprise a phosphatase complex that is involved in nuclear envelope reformation and regulation of the DNA damage response. The encoded protein may also play a role in cancer progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
|
| Allele List at MGI |
All alleles(24) : Gene trapped(24)
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2610318N02Rik |
A |
G |
16: 16,939,260 (GRCm39) |
L41P |
probably damaging |
Het |
| Aff4 |
C |
T |
11: 53,290,446 (GRCm39) |
L469F |
probably damaging |
Het |
| AI182371 |
G |
A |
2: 34,975,366 (GRCm39) |
H288Y |
probably benign |
Het |
| AK157302 |
A |
T |
13: 21,679,827 (GRCm39) |
K118* |
probably null |
Het |
| Arhgef2 |
G |
A |
3: 88,543,351 (GRCm39) |
R454Q |
probably damaging |
Het |
| Asb17 |
C |
T |
3: 153,550,322 (GRCm39) |
T118M |
probably damaging |
Het |
| Atp7b |
A |
G |
8: 22,503,600 (GRCm39) |
V718A |
possibly damaging |
Het |
| Cdh20 |
G |
T |
1: 109,976,594 (GRCm39) |
L86F |
probably damaging |
Het |
| Cela2a |
A |
T |
4: 141,545,350 (GRCm39) |
|
probably null |
Het |
| Cers3 |
T |
A |
7: 66,433,162 (GRCm39) |
Y160N |
probably damaging |
Het |
| Chmp2b |
A |
G |
16: 65,343,877 (GRCm39) |
V56A |
probably benign |
Het |
| Cryl1 |
A |
G |
14: 57,635,880 (GRCm39) |
V9A |
unknown |
Het |
| Dmbt1 |
A |
T |
7: 130,699,305 (GRCm39) |
H978L |
possibly damaging |
Het |
| Dnm1 |
C |
T |
2: 32,204,949 (GRCm39) |
V673M |
probably damaging |
Het |
| Dtx4 |
T |
A |
19: 12,462,646 (GRCm39) |
K378* |
probably null |
Het |
| Extl1 |
A |
T |
4: 134,090,491 (GRCm39) |
M328K |
possibly damaging |
Het |
| Fcgbp |
T |
C |
7: 27,806,628 (GRCm39) |
S2199P |
probably benign |
Het |
| Glis3 |
G |
T |
19: 28,508,702 (GRCm39) |
N427K |
probably benign |
Het |
| Hdac7 |
T |
C |
15: 97,691,944 (GRCm39) |
K810E |
probably benign |
Het |
| Hesx1 |
A |
G |
14: 26,723,434 (GRCm39) |
E88G |
probably benign |
Het |
| Hmcn2 |
A |
T |
2: 31,350,361 (GRCm39) |
Q5086L |
possibly damaging |
Het |
| Ier3 |
A |
G |
17: 36,133,101 (GRCm39) |
T128A |
probably benign |
Het |
| Igsf10 |
G |
T |
3: 59,239,101 (GRCm39) |
T360K |
probably damaging |
Het |
| Ilkap |
A |
C |
1: 91,312,345 (GRCm39) |
C2G |
possibly damaging |
Het |
| Itih1 |
A |
G |
14: 30,660,028 (GRCm39) |
F231S |
probably damaging |
Het |
| Jrkl |
A |
T |
9: 13,244,913 (GRCm39) |
Y249* |
probably null |
Het |
| Kat6a |
AGAGGAGGAGGAGGAGGAGGAGGAG |
AGAGGAGGAGGAGGAGGAGGAG |
8: 23,425,663 (GRCm39) |
|
probably benign |
Het |
| Katnal2 |
A |
T |
18: 77,098,637 (GRCm39) |
S184R |
probably benign |
Het |
| Kcnh5 |
T |
A |
12: 74,945,230 (GRCm39) |
|
probably null |
Het |
| Kcnj11 |
G |
T |
7: 45,748,781 (GRCm39) |
L181I |
probably damaging |
Het |
| Klhl2 |
T |
C |
8: 65,202,804 (GRCm39) |
T465A |
probably benign |
Het |
| Krt90 |
T |
A |
15: 101,471,046 (GRCm39) |
Y72F |
probably benign |
Het |
| Lig4 |
G |
A |
8: 10,022,766 (GRCm39) |
T338I |
probably benign |
Het |
| Lrrc37 |
T |
C |
11: 103,511,285 (GRCm39) |
T228A |
unknown |
Het |
| Magel2 |
T |
C |
7: 62,030,540 (GRCm39) |
V1148A |
unknown |
Het |
| Mak |
C |
A |
13: 41,186,020 (GRCm39) |
E549D |
probably benign |
Het |
| Marf1 |
G |
T |
16: 13,950,293 (GRCm39) |
S1001Y |
probably damaging |
Het |
| Mcoln1 |
G |
A |
8: 3,561,787 (GRCm39) |
V446I |
probably damaging |
Het |
| Meig1 |
T |
C |
2: 3,410,290 (GRCm39) |
N70S |
probably benign |
Het |
| Mfsd14a |
G |
A |
3: 116,441,479 (GRCm39) |
T108I |
probably damaging |
Het |
| Mocs1 |
G |
A |
17: 49,761,386 (GRCm39) |
M493I |
probably damaging |
Het |
| Mrpl11 |
C |
A |
19: 5,012,497 (GRCm39) |
A26E |
probably damaging |
Het |
| Myh6 |
A |
T |
14: 55,191,251 (GRCm39) |
D863E |
probably benign |
Het |
| Myom2 |
T |
A |
8: 15,134,555 (GRCm39) |
Y453N |
probably damaging |
Het |
| Nhlh1 |
A |
G |
1: 171,881,524 (GRCm39) |
I114T |
probably damaging |
Het |
| Odr4 |
A |
G |
1: 150,258,086 (GRCm39) |
V183A |
possibly damaging |
Het |
| Or12j4 |
A |
C |
7: 140,046,504 (GRCm39) |
H130P |
probably benign |
Het |
| Or2y3 |
G |
T |
17: 38,393,071 (GRCm39) |
P266Q |
probably damaging |
Het |
| Or4k5 |
A |
T |
14: 50,386,154 (GRCm39) |
M59K |
probably damaging |
Het |
| Or5k17 |
G |
T |
16: 58,746,486 (GRCm39) |
F149L |
probably benign |
Het |
| Or5p80 |
C |
G |
7: 108,229,984 (GRCm39) |
P262A |
probably damaging |
Het |
| Pclo |
T |
C |
5: 14,764,309 (GRCm39) |
S976P |
probably benign |
Het |
| Pde3a |
G |
A |
6: 141,429,640 (GRCm39) |
E734K |
possibly damaging |
Het |
| Pdzd2 |
A |
T |
15: 12,375,879 (GRCm39) |
S1419T |
probably benign |
Het |
| Pdzd8 |
T |
A |
19: 59,288,853 (GRCm39) |
Y849F |
probably damaging |
Het |
| Phldb3 |
A |
G |
7: 24,312,070 (GRCm39) |
E128G |
probably damaging |
Het |
| Polg |
A |
G |
7: 79,111,468 (GRCm39) |
I261T |
possibly damaging |
Het |
| Ppp1r35 |
T |
C |
5: 137,778,267 (GRCm39) |
M254T |
probably benign |
Het |
| Ppp3ca |
G |
T |
3: 136,596,211 (GRCm39) |
R292M |
possibly damaging |
Het |
| Ptk7 |
T |
A |
17: 46,890,543 (GRCm39) |
T430S |
probably benign |
Het |
| Ptrh1 |
T |
A |
2: 32,667,040 (GRCm39) |
N144K |
possibly damaging |
Het |
| Rbfox1 |
A |
G |
16: 7,111,946 (GRCm39) |
T211A |
possibly damaging |
Het |
| Rbpjl |
A |
G |
2: 164,256,343 (GRCm39) |
D443G |
possibly damaging |
Het |
| Rcc1 |
A |
G |
4: 132,065,360 (GRCm39) |
|
probably null |
Het |
| Rimbp2 |
G |
T |
5: 128,865,229 (GRCm39) |
S706R |
probably damaging |
Het |
| Rsph10b |
G |
C |
5: 143,898,074 (GRCm39) |
E96D |
probably benign |
Het |
| Scn10a |
A |
T |
9: 119,438,514 (GRCm39) |
I1784K |
probably benign |
Het |
| Sfxn2 |
A |
G |
19: 46,579,985 (GRCm39) |
|
probably null |
Het |
| Slamf6 |
T |
A |
1: 171,765,575 (GRCm39) |
L233Q |
probably damaging |
Het |
| Slc17a5 |
A |
T |
9: 78,484,455 (GRCm39) |
Y102N |
probably damaging |
Het |
| Slc25a53 |
T |
C |
X: 135,884,216 (GRCm39) |
T42A |
probably damaging |
Het |
| Slco1a8 |
T |
C |
6: 141,926,670 (GRCm39) |
D552G |
probably damaging |
Het |
| Smg7 |
G |
A |
1: 152,716,064 (GRCm39) |
T1057I |
possibly damaging |
Het |
| Speer2 |
T |
A |
16: 69,657,485 (GRCm39) |
T53S |
possibly damaging |
Het |
| Srm |
A |
C |
4: 148,676,948 (GRCm39) |
I100L |
probably benign |
Het |
| Stoml3 |
A |
C |
3: 53,415,008 (GRCm39) |
N267H |
probably damaging |
Het |
| Thsd7a |
A |
C |
6: 12,379,632 (GRCm39) |
C931G |
probably damaging |
Het |
| Tlr11 |
A |
G |
14: 50,598,139 (GRCm39) |
I42V |
probably benign |
Het |
| Tmigd1 |
T |
C |
11: 76,800,999 (GRCm39) |
V162A |
probably benign |
Het |
| Tmx3 |
A |
G |
18: 90,528,505 (GRCm39) |
|
probably null |
Het |
| Topors |
T |
A |
4: 40,262,790 (GRCm39) |
R165W |
possibly damaging |
Het |
| Ttc17 |
A |
T |
2: 94,196,987 (GRCm39) |
S453R |
possibly damaging |
Het |
| Vmn1r49 |
G |
T |
6: 90,049,441 (GRCm39) |
T187N |
probably damaging |
Het |
| Zbtb49 |
A |
T |
5: 38,371,464 (GRCm39) |
V139E |
possibly damaging |
Het |
| Zfp11 |
T |
C |
5: 129,734,216 (GRCm39) |
H415R |
probably damaging |
Het |
| Zfp677 |
A |
T |
17: 21,617,970 (GRCm39) |
K342N |
probably benign |
Het |
| Zfp979 |
A |
C |
4: 147,697,915 (GRCm39) |
C265G |
possibly damaging |
Het |
| Zfpl1 |
T |
C |
19: 6,134,459 (GRCm39) |
R9G |
probably damaging |
Het |
| Zkscan8 |
A |
T |
13: 21,704,759 (GRCm39) |
C321* |
probably null |
Het |
|
| Other mutations in Cdca2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01115:Cdca2
|
APN |
14 |
67,952,146 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01413:Cdca2
|
APN |
14 |
67,915,343 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01962:Cdca2
|
APN |
14 |
67,943,172 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01982:Cdca2
|
APN |
14 |
67,915,168 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02198:Cdca2
|
APN |
14 |
67,932,445 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02208:Cdca2
|
APN |
14 |
67,950,589 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02883:Cdca2
|
APN |
14 |
67,944,946 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03069:Cdca2
|
APN |
14 |
67,952,385 (GRCm39) |
splice site |
probably benign |
|
|
F5493:Cdca2
|
UTSW |
14 |
67,915,141 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03046:Cdca2
|
UTSW |
14 |
67,937,471 (GRCm39) |
intron |
probably benign |
|
|
R0254:Cdca2
|
UTSW |
14 |
67,914,627 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0350:Cdca2
|
UTSW |
14 |
67,950,568 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0368:Cdca2
|
UTSW |
14 |
67,937,796 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0398:Cdca2
|
UTSW |
14 |
67,935,411 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0790:Cdca2
|
UTSW |
14 |
67,917,740 (GRCm39) |
missense |
probably benign |
|
|
R1104:Cdca2
|
UTSW |
14 |
67,931,131 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1474:Cdca2
|
UTSW |
14 |
67,952,355 (GRCm39) |
intron |
probably benign |
|
|
R1658:Cdca2
|
UTSW |
14 |
67,915,148 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1782:Cdca2
|
UTSW |
14 |
67,915,260 (GRCm39) |
missense |
probably benign |
0.22 |
|
R2150:Cdca2
|
UTSW |
14 |
67,952,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2154:Cdca2
|
UTSW |
14 |
67,914,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2862:Cdca2
|
UTSW |
14 |
67,935,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3156:Cdca2
|
UTSW |
14 |
67,935,612 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R3840:Cdca2
|
UTSW |
14 |
67,917,720 (GRCm39) |
nonsense |
probably null |
|
|
R4043:Cdca2
|
UTSW |
14 |
67,941,455 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4293:Cdca2
|
UTSW |
14 |
67,952,299 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4679:Cdca2
|
UTSW |
14 |
67,952,415 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4777:Cdca2
|
UTSW |
14 |
67,950,589 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4829:Cdca2
|
UTSW |
14 |
67,931,202 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4843:Cdca2
|
UTSW |
14 |
67,914,425 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5031:Cdca2
|
UTSW |
14 |
67,950,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5181:Cdca2
|
UTSW |
14 |
67,917,614 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5331:Cdca2
|
UTSW |
14 |
67,914,920 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5490:Cdca2
|
UTSW |
14 |
67,917,733 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5695:Cdca2
|
UTSW |
14 |
67,943,078 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6246:Cdca2
|
UTSW |
14 |
67,915,277 (GRCm39) |
nonsense |
probably null |
|
|
R6866:Cdca2
|
UTSW |
14 |
67,931,115 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6928:Cdca2
|
UTSW |
14 |
67,943,193 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6955:Cdca2
|
UTSW |
14 |
67,952,453 (GRCm39) |
start codon destroyed |
probably null |
0.53 |
|
R6986:Cdca2
|
UTSW |
14 |
67,932,446 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7080:Cdca2
|
UTSW |
14 |
67,935,551 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7092:Cdca2
|
UTSW |
14 |
67,944,800 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7292:Cdca2
|
UTSW |
14 |
67,915,326 (GRCm39) |
nonsense |
probably null |
|
|
R7308:Cdca2
|
UTSW |
14 |
67,932,440 (GRCm39) |
missense |
probably benign |
|
|
R7310:Cdca2
|
UTSW |
14 |
67,950,673 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7877:Cdca2
|
UTSW |
14 |
67,914,665 (GRCm39) |
missense |
probably benign |
|
|
R8012:Cdca2
|
UTSW |
14 |
67,914,821 (GRCm39) |
missense |
probably benign |
0.23 |
|
R8080:Cdca2
|
UTSW |
14 |
67,915,004 (GRCm39) |
nonsense |
probably null |
|
|
R8772:Cdca2
|
UTSW |
14 |
67,935,529 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9123:Cdca2
|
UTSW |
14 |
67,917,762 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9125:Cdca2
|
UTSW |
14 |
67,917,762 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9252:Cdca2
|
UTSW |
14 |
67,914,831 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9328:Cdca2
|
UTSW |
14 |
67,931,131 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9406:Cdca2
|
UTSW |
14 |
67,937,772 (GRCm39) |
missense |
unknown |
|
|
R9667:Cdca2
|
UTSW |
14 |
67,915,003 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9678:Cdca2
|
UTSW |
14 |
67,937,778 (GRCm39) |
missense |
unknown |
|
|
Z1088:Cdca2
|
UTSW |
14 |
67,937,747 (GRCm39) |
missense |
probably benign |
0.12 |
|
Z1177:Cdca2
|
UTSW |
14 |
67,917,693 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CATGTATAATTGGGGCCTACTACAG -3'
(R):5'- AGATGGATGCGAGTTCACACG -3'
Sequencing Primer
(F):5'- AATTGGGGCCTACTACAGTTACTG -3'
(R):5'- TGCGAGTTCACACGACAAG -3'
|
| Posted On |
2014-10-01 |
Incidental Mutation