Incidental Mutation 'R4631:Dnajc13'
| ID |
349202 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dnajc13
|
| Ensembl Gene |
ENSMUSG00000032560 |
| Gene Name |
DnaJ heat shock protein family (Hsp40) member C13 |
| Synonyms |
Rme8, D030002L11Rik, LOC382100 |
| MMRRC Submission |
041896-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.940)
|
| Stock # |
R4631 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
104028481-104140129 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 104067616 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Threonine
at position 1181
(M1181T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000139804
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000035170]
[ENSMUST00000186788]
|
| AlphaFold |
D4AFX7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000035170
AA Change: M1176T
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000035170
Gene: ENSMUSG00000032560
AA Change: M1176T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
706 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
832 |
843 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
926 |
N/A |
INTRINSIC |
|
Blast:ARM
|
927 |
963 |
6e-12 |
BLAST |
|
Pfam:DUF4339
|
976 |
1020 |
1.5e-18 |
PFAM |
|
Blast:ARM
|
1071 |
1110 |
5e-12 |
BLAST |
|
DnaJ
|
1300 |
1358 |
5.69e-18 |
SMART |
|
low complexity region
|
1417 |
1426 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1829 |
N/A |
INTRINSIC |
|
Blast:ARM
|
1843 |
1884 |
6e-8 |
BLAST |
|
low complexity region
|
1968 |
1984 |
N/A |
INTRINSIC |
|
low complexity region
|
2006 |
2016 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000185503
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000186788
AA Change: M1181T
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000139804
Gene: ENSMUSG00000032560
AA Change: M1181T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
706 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
837 |
848 |
N/A |
INTRINSIC |
|
low complexity region
|
918 |
931 |
N/A |
INTRINSIC |
|
Blast:ARM
|
932 |
968 |
6e-12 |
BLAST |
|
Pfam:DUF4339
|
980 |
1025 |
8.1e-14 |
PFAM |
|
Blast:ARM
|
1076 |
1115 |
5e-12 |
BLAST |
|
DnaJ
|
1305 |
1363 |
5.69e-18 |
SMART |
|
low complexity region
|
1422 |
1431 |
N/A |
INTRINSIC |
|
low complexity region
|
1818 |
1834 |
N/A |
INTRINSIC |
|
Blast:ARM
|
1848 |
1889 |
6e-8 |
BLAST |
|
low complexity region
|
1973 |
1989 |
N/A |
INTRINSIC |
|
low complexity region
|
2011 |
2021 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000189103
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000191199
|
| Meta Mutation Damage Score |
0.7272 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.2%
- 20x: 95.0%
|
| Validation Efficiency |
100% (84/84) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the Dnaj protein family whose members act as co-chaperones of a partner heat-shock protein by binding to the latter and stimulating ATP hydrolysis. The encoded protein associates with the heat-shock protein Hsc70 and plays a role in clathrin-mediated endocytosis. It may also be involved in post-endocytic transport mechanisms via its associations with other proteins, including the sorting nexin SNX1. Mutations in this gene are associated with Parkinson's disease. [provided by RefSeq, Jun 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 77 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1700017B05Rik |
A |
T |
9: 57,165,270 (GRCm39) |
L368Q |
probably damaging |
Het |
| Abcc2 |
C |
T |
19: 43,803,146 (GRCm39) |
P661S |
possibly damaging |
Het |
| Adgre4 |
T |
G |
17: 56,121,305 (GRCm39) |
M457R |
probably null |
Het |
| Ank |
C |
A |
15: 27,467,176 (GRCm39) |
F29L |
probably benign |
Het |
| Arhgap20 |
T |
C |
9: 51,751,653 (GRCm39) |
|
probably benign |
Het |
| Atf6 |
T |
C |
1: 170,574,766 (GRCm39) |
|
probably null |
Het |
| Bhmt1b |
G |
A |
18: 87,774,525 (GRCm39) |
R16H |
probably damaging |
Het |
| Bod1l |
A |
G |
5: 41,975,078 (GRCm39) |
F2079L |
probably damaging |
Het |
| Cd163 |
T |
C |
6: 124,306,045 (GRCm39) |
*1122Q |
probably null |
Het |
| Ces2g |
T |
C |
8: 105,694,094 (GRCm39) |
|
probably null |
Het |
| Cntnap3 |
A |
G |
13: 64,926,697 (GRCm39) |
Y558H |
probably benign |
Het |
| Ctsm |
T |
A |
13: 61,685,510 (GRCm39) |
S301C |
probably null |
Het |
| Dlc1 |
A |
C |
8: 37,404,712 (GRCm39) |
|
probably null |
Het |
| Dlg2 |
A |
T |
7: 91,737,822 (GRCm39) |
I435F |
probably damaging |
Het |
| Dnah5 |
T |
C |
15: 28,402,099 (GRCm39) |
V3420A |
probably damaging |
Het |
| Dnah5 |
T |
A |
15: 28,420,140 (GRCm39) |
Y3813N |
probably damaging |
Het |
| Drc3 |
C |
A |
11: 60,255,734 (GRCm39) |
T107N |
probably benign |
Het |
| Dydc2 |
T |
C |
14: 40,771,286 (GRCm39) |
E131G |
probably benign |
Het |
| Eif5b |
T |
C |
1: 38,080,828 (GRCm39) |
V723A |
probably damaging |
Het |
| Fndc9 |
C |
A |
11: 46,128,675 (GRCm39) |
H65N |
possibly damaging |
Het |
| Fzd1 |
A |
T |
5: 4,805,865 (GRCm39) |
Y572* |
probably null |
Het |
| Gps1 |
T |
A |
11: 120,679,065 (GRCm39) |
|
probably null |
Het |
| Gvin3 |
A |
G |
7: 106,198,730 (GRCm39) |
|
noncoding transcript |
Het |
| Kazn |
G |
A |
4: 141,845,471 (GRCm39) |
|
probably benign |
Het |
| Kcnd3 |
C |
T |
3: 105,566,082 (GRCm39) |
A421V |
probably damaging |
Het |
| Kcnip1 |
T |
A |
11: 33,942,821 (GRCm39) |
|
noncoding transcript |
Het |
| Kif19a |
A |
G |
11: 114,675,673 (GRCm39) |
I382V |
possibly damaging |
Het |
| Krt1 |
C |
T |
15: 101,754,622 (GRCm39) |
G543S |
unknown |
Het |
| Malsu1 |
A |
T |
6: 49,061,467 (GRCm39) |
E177V |
probably damaging |
Het |
| Man2a2 |
A |
G |
7: 80,012,211 (GRCm39) |
F649L |
probably benign |
Het |
| Map3k11 |
A |
G |
19: 5,740,941 (GRCm39) |
I223V |
probably benign |
Het |
| Mroh2a |
A |
G |
1: 88,186,386 (GRCm39) |
S64G |
probably benign |
Het |
| Myh9 |
T |
G |
15: 77,681,228 (GRCm39) |
D164A |
probably damaging |
Het |
| Myo16 |
T |
C |
8: 10,556,984 (GRCm39) |
I1040T |
probably damaging |
Het |
| Myo18b |
C |
T |
5: 112,994,266 (GRCm39) |
A896T |
probably damaging |
Het |
| Myocd |
G |
T |
11: 65,069,685 (GRCm39) |
N798K |
probably benign |
Het |
| Or13c7b |
T |
C |
4: 43,820,563 (GRCm39) |
D266G |
probably benign |
Het |
| Or1n1b |
T |
G |
2: 36,780,630 (GRCm39) |
T77P |
probably benign |
Het |
| Or2l13b |
G |
A |
16: 19,348,891 (GRCm39) |
R260* |
probably null |
Het |
| Or4c11 |
C |
T |
2: 88,695,174 (GRCm39) |
T75I |
probably benign |
Het |
| Or4g7 |
T |
A |
2: 111,309,908 (GRCm39) |
W260R |
probably damaging |
Het |
| Or52a5 |
A |
T |
7: 103,426,682 (GRCm39) |
L290Q |
probably damaging |
Het |
| Or5b105 |
T |
A |
19: 13,080,636 (GRCm39) |
I11F |
probably benign |
Het |
| Pcdh18 |
T |
A |
3: 49,710,890 (GRCm39) |
I142F |
probably damaging |
Het |
| Pcyox1 |
T |
C |
6: 86,366,212 (GRCm39) |
E334G |
possibly damaging |
Het |
| Pcyox1 |
T |
C |
6: 86,366,125 (GRCm39) |
D363G |
probably benign |
Het |
| Pgm2 |
A |
G |
5: 64,263,290 (GRCm39) |
|
probably null |
Het |
| Plagl1 |
T |
G |
10: 13,003,743 (GRCm39) |
|
probably benign |
Het |
| Ppp1r9a |
A |
G |
6: 4,906,537 (GRCm39) |
D364G |
possibly damaging |
Het |
| Rab2b |
T |
A |
14: 52,503,699 (GRCm39) |
H141L |
possibly damaging |
Het |
| Rev3l |
A |
G |
10: 39,704,412 (GRCm39) |
K279E |
probably benign |
Het |
| Rnf111 |
G |
T |
9: 70,357,678 (GRCm39) |
T607N |
probably benign |
Het |
| Scn8a |
C |
A |
15: 100,914,384 (GRCm39) |
S1130* |
probably null |
Het |
| Selenbp1 |
A |
G |
3: 94,851,879 (GRCm39) |
*473W |
probably null |
Het |
| Sh3bp4 |
A |
C |
1: 89,071,995 (GRCm39) |
D281A |
probably damaging |
Het |
| Skint5 |
T |
A |
4: 113,486,314 (GRCm39) |
|
probably null |
Het |
| Slc1a4 |
A |
G |
11: 20,258,452 (GRCm39) |
L249P |
probably damaging |
Het |
| Slc45a2 |
T |
A |
15: 11,012,662 (GRCm39) |
S222T |
probably benign |
Het |
| Slc7a4 |
A |
G |
16: 17,392,255 (GRCm39) |
F393S |
probably damaging |
Het |
| Slc9a2 |
A |
T |
1: 40,801,078 (GRCm39) |
D536V |
possibly damaging |
Het |
| Stra6 |
T |
A |
9: 58,048,115 (GRCm39) |
|
probably benign |
Het |
| Tmem145 |
A |
G |
7: 25,007,250 (GRCm39) |
D156G |
probably benign |
Het |
| Tns3 |
A |
C |
11: 8,401,119 (GRCm39) |
F1060V |
probably benign |
Het |
| Trak1 |
G |
A |
9: 121,283,491 (GRCm39) |
R419Q |
probably benign |
Het |
| Trappc8 |
A |
G |
18: 21,000,865 (GRCm39) |
S273P |
probably benign |
Het |
| Trmt11 |
A |
G |
10: 30,435,200 (GRCm39) |
S320P |
probably benign |
Het |
| Ugt1a6a |
A |
T |
1: 88,066,980 (GRCm39) |
Y262F |
probably benign |
Het |
| Vmn1r73 |
G |
A |
7: 11,490,758 (GRCm39) |
C192Y |
probably benign |
Het |
| Vmn2r103 |
T |
C |
17: 20,013,958 (GRCm39) |
I250T |
probably benign |
Het |
| Vmn2r25 |
T |
A |
6: 123,829,962 (GRCm39) |
D63V |
possibly damaging |
Het |
| Vps13b |
C |
T |
15: 35,646,278 (GRCm39) |
H1461Y |
possibly damaging |
Het |
| Ythdc2 |
A |
T |
18: 45,020,698 (GRCm39) |
E1427D |
probably benign |
Het |
| Zbed6 |
A |
T |
1: 133,586,482 (GRCm39) |
V285E |
probably damaging |
Het |
| Zbtb26 |
A |
G |
2: 37,326,968 (GRCm39) |
F23L |
probably benign |
Het |
| Zfp62 |
T |
A |
11: 49,108,632 (GRCm39) |
*908R |
probably null |
Het |
| Zfp975 |
A |
T |
7: 42,312,369 (GRCm39) |
N81K |
probably benign |
Het |
| Zkscan16 |
G |
A |
4: 58,951,918 (GRCm39) |
V198M |
probably damaging |
Het |
|
| Other mutations in Dnajc13 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00743:Dnajc13
|
APN |
9 |
104,039,979 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL00754:Dnajc13
|
APN |
9 |
104,051,697 (GRCm39) |
nonsense |
probably null |
|
|
IGL00914:Dnajc13
|
APN |
9 |
104,090,081 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01014:Dnajc13
|
APN |
9 |
104,080,417 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01077:Dnajc13
|
APN |
9 |
104,108,220 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL01137:Dnajc13
|
APN |
9 |
104,037,689 (GRCm39) |
missense |
probably benign |
|
|
IGL01305:Dnajc13
|
APN |
9 |
104,107,836 (GRCm39) |
splice site |
probably null |
|
|
IGL01707:Dnajc13
|
APN |
9 |
104,106,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01781:Dnajc13
|
APN |
9 |
104,039,558 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL01868:Dnajc13
|
APN |
9 |
104,039,944 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
IGL01950:Dnajc13
|
APN |
9 |
104,067,631 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02102:Dnajc13
|
APN |
9 |
104,106,208 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL02350:Dnajc13
|
APN |
9 |
104,039,558 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02357:Dnajc13
|
APN |
9 |
104,039,558 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02470:Dnajc13
|
APN |
9 |
104,052,946 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02888:Dnajc13
|
APN |
9 |
104,057,261 (GRCm39) |
splice site |
probably benign |
|
|
IGL03079:Dnajc13
|
APN |
9 |
104,090,068 (GRCm39) |
nonsense |
probably null |
|
|
IGL03179:Dnajc13
|
APN |
9 |
104,044,634 (GRCm39) |
missense |
probably benign |
0.42 |
|
IGL03293:Dnajc13
|
APN |
9 |
104,051,625 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
impressario
|
UTSW |
9 |
104,091,085 (GRCm39) |
missense |
probably benign |
0.12 |
|
Kaiser
|
UTSW |
9 |
104,091,387 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB008:Dnajc13
|
UTSW |
9 |
104,095,763 (GRCm39) |
missense |
probably benign |
0.02 |
|
BB018:Dnajc13
|
UTSW |
9 |
104,095,763 (GRCm39) |
missense |
probably benign |
0.02 |
|
PIT4142001:Dnajc13
|
UTSW |
9 |
104,115,672 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0323:Dnajc13
|
UTSW |
9 |
104,034,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0361:Dnajc13
|
UTSW |
9 |
104,044,258 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0480:Dnajc13
|
UTSW |
9 |
104,077,708 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0558:Dnajc13
|
UTSW |
9 |
104,079,151 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0707:Dnajc13
|
UTSW |
9 |
104,049,781 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0831:Dnajc13
|
UTSW |
9 |
104,049,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1234:Dnajc13
|
UTSW |
9 |
104,091,356 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R1433:Dnajc13
|
UTSW |
9 |
104,057,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1463:Dnajc13
|
UTSW |
9 |
104,056,139 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1464:Dnajc13
|
UTSW |
9 |
104,091,366 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1464:Dnajc13
|
UTSW |
9 |
104,091,366 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1489:Dnajc13
|
UTSW |
9 |
104,108,234 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1575:Dnajc13
|
UTSW |
9 |
104,034,037 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1750:Dnajc13
|
UTSW |
9 |
104,098,676 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1903:Dnajc13
|
UTSW |
9 |
104,106,136 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2066:Dnajc13
|
UTSW |
9 |
104,098,640 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2206:Dnajc13
|
UTSW |
9 |
104,080,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3160:Dnajc13
|
UTSW |
9 |
104,097,097 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R3162:Dnajc13
|
UTSW |
9 |
104,097,097 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R4158:Dnajc13
|
UTSW |
9 |
104,067,641 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4460:Dnajc13
|
UTSW |
9 |
104,058,262 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4537:Dnajc13
|
UTSW |
9 |
104,064,004 (GRCm39) |
intron |
probably benign |
|
|
R4538:Dnajc13
|
UTSW |
9 |
104,064,004 (GRCm39) |
intron |
probably benign |
|
|
R4662:Dnajc13
|
UTSW |
9 |
104,084,957 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4722:Dnajc13
|
UTSW |
9 |
104,091,017 (GRCm39) |
missense |
probably benign |
|
|
R4731:Dnajc13
|
UTSW |
9 |
104,064,004 (GRCm39) |
intron |
probably benign |
|
|
R4732:Dnajc13
|
UTSW |
9 |
104,064,004 (GRCm39) |
intron |
probably benign |
|
|
R4758:Dnajc13
|
UTSW |
9 |
104,049,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4801:Dnajc13
|
UTSW |
9 |
104,052,926 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4802:Dnajc13
|
UTSW |
9 |
104,052,926 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4928:Dnajc13
|
UTSW |
9 |
104,110,837 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4944:Dnajc13
|
UTSW |
9 |
104,044,586 (GRCm39) |
unclassified |
probably benign |
|
|
R4979:Dnajc13
|
UTSW |
9 |
104,063,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5177:Dnajc13
|
UTSW |
9 |
104,108,185 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5190:Dnajc13
|
UTSW |
9 |
104,051,724 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5256:Dnajc13
|
UTSW |
9 |
104,080,528 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5452:Dnajc13
|
UTSW |
9 |
104,069,313 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5657:Dnajc13
|
UTSW |
9 |
104,105,736 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5752:Dnajc13
|
UTSW |
9 |
104,069,973 (GRCm39) |
splice site |
probably null |
|
|
R5789:Dnajc13
|
UTSW |
9 |
104,091,387 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5837:Dnajc13
|
UTSW |
9 |
104,053,865 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5846:Dnajc13
|
UTSW |
9 |
104,067,584 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5982:Dnajc13
|
UTSW |
9 |
104,061,814 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R6189:Dnajc13
|
UTSW |
9 |
104,091,085 (GRCm39) |
missense |
probably benign |
0.12 |
|
R6355:Dnajc13
|
UTSW |
9 |
104,080,469 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6483:Dnajc13
|
UTSW |
9 |
104,085,003 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6613:Dnajc13
|
UTSW |
9 |
104,091,076 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6962:Dnajc13
|
UTSW |
9 |
104,058,208 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7048:Dnajc13
|
UTSW |
9 |
104,080,613 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7101:Dnajc13
|
UTSW |
9 |
104,042,221 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7304:Dnajc13
|
UTSW |
9 |
104,115,713 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7353:Dnajc13
|
UTSW |
9 |
104,107,230 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7366:Dnajc13
|
UTSW |
9 |
104,061,905 (GRCm39) |
missense |
probably benign |
0.43 |
|
R7528:Dnajc13
|
UTSW |
9 |
104,056,164 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7635:Dnajc13
|
UTSW |
9 |
104,039,566 (GRCm39) |
missense |
probably benign |
|
|
R7673:Dnajc13
|
UTSW |
9 |
104,110,891 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7856:Dnajc13
|
UTSW |
9 |
104,044,684 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7931:Dnajc13
|
UTSW |
9 |
104,095,763 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7995:Dnajc13
|
UTSW |
9 |
104,051,562 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8319:Dnajc13
|
UTSW |
9 |
104,067,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8354:Dnajc13
|
UTSW |
9 |
104,094,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8680:Dnajc13
|
UTSW |
9 |
104,057,338 (GRCm39) |
missense |
probably benign |
|
|
R8686:Dnajc13
|
UTSW |
9 |
104,048,004 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8707:Dnajc13
|
UTSW |
9 |
104,069,847 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8847:Dnajc13
|
UTSW |
9 |
104,057,360 (GRCm39) |
nonsense |
probably null |
|
|
R8868:Dnajc13
|
UTSW |
9 |
104,042,987 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8986:Dnajc13
|
UTSW |
9 |
104,057,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9139:Dnajc13
|
UTSW |
9 |
104,085,039 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9334:Dnajc13
|
UTSW |
9 |
104,051,659 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9353:Dnajc13
|
UTSW |
9 |
104,067,571 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9470:Dnajc13
|
UTSW |
9 |
104,107,919 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9528:Dnajc13
|
UTSW |
9 |
104,114,904 (GRCm39) |
missense |
probably benign |
|
|
R9578:Dnajc13
|
UTSW |
9 |
104,115,726 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9658:Dnajc13
|
UTSW |
9 |
104,115,728 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9691:Dnajc13
|
UTSW |
9 |
104,042,211 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0017:Dnajc13
|
UTSW |
9 |
104,115,677 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
X0028:Dnajc13
|
UTSW |
9 |
104,042,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AATCTTGCAATGGAGAGCAGGC -3'
(R):5'- TCCCTAGAGCACAGAAGTGG -3'
Sequencing Primer
(F):5'- GCCAGGTGATGAGCAGC -3'
(R):5'- GCTACCTGGCCTTGAACTCATAGAG -3'
|
| Posted On |
2015-10-08 |
Incidental Mutation