Incidental Mutation 'R4831:Mtus1'
| ID |
372814 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Mtus1
|
| Ensembl Gene |
ENSMUSG00000045636 |
| Gene Name |
mitochondrial tumor suppressor 1 |
| Synonyms |
MTSG1, B430305I03Rik, MD44, Atip1 |
| MMRRC Submission |
042447-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.241)
|
| Stock # |
R4831 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
8 |
| Chromosomal Location |
41443951-41586763 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to G
at 41536189 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Threonine
at position 509
(R509T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112626
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000059115]
[ENSMUST00000118835]
[ENSMUST00000145860]
[ENSMUST00000155055]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000059115
AA Change: R509T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000059503
Gene: ENSMUSG00000045636
AA Change: R509T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
524 |
539 |
N/A |
INTRINSIC |
|
coiled coil region
|
876 |
938 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
1021 |
1156 |
3e-7 |
SMART |
|
low complexity region
|
1195 |
1209 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000118835
AA Change: R509T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000112626
Gene: ENSMUSG00000045636
AA Change: R509T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
524 |
539 |
N/A |
INTRINSIC |
|
coiled coil region
|
876 |
938 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
1021 |
1156 |
3e-7 |
SMART |
|
low complexity region
|
1195 |
1209 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000143853
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000145860
AA Change: R509T
PolyPhen 2
Score 0.958 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000119440
Gene: ENSMUSG00000045636
AA Change: R509T
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
524 |
539 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155055
|
| Meta Mutation Damage Score |
0.1996 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.3%
|
| Validation Efficiency |
99% (96/97) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a gene trap allele exhibit spontaneous heart hypertrophy and SLE-like lymphoproliferative disease. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810408A11Rik |
C |
T |
11: 69,791,403 (GRCm39) |
V59I |
possibly damaging |
Het |
| 4930544M13Rik |
T |
G |
13: 114,744,183 (GRCm39) |
|
noncoding transcript |
Het |
| Abca13 |
A |
T |
11: 9,492,077 (GRCm39) |
K4373* |
probably null |
Het |
| Abtb2 |
A |
T |
2: 103,513,820 (GRCm39) |
T410S |
probably benign |
Het |
| Adamts13 |
T |
C |
2: 26,873,142 (GRCm39) |
|
probably null |
Het |
| Ahnak2 |
C |
G |
12: 112,742,183 (GRCm39) |
D630H |
probably damaging |
Het |
| Aox3 |
T |
C |
1: 58,191,725 (GRCm39) |
S426P |
probably damaging |
Het |
| Atxn10 |
C |
T |
15: 85,271,260 (GRCm39) |
S266F |
probably benign |
Het |
| B4galnt4 |
G |
T |
7: 140,647,634 (GRCm39) |
M407I |
probably damaging |
Het |
| B4galnt4 |
T |
A |
7: 140,644,470 (GRCm39) |
|
probably null |
Het |
| Bclaf1 |
T |
A |
10: 20,197,872 (GRCm39) |
|
probably benign |
Het |
| C4b |
C |
T |
17: 34,955,864 (GRCm39) |
|
probably null |
Het |
| Cdc42bpg |
T |
C |
19: 6,361,365 (GRCm39) |
F297S |
probably damaging |
Het |
| Cdh10 |
A |
T |
15: 19,013,664 (GRCm39) |
T755S |
probably benign |
Het |
| Ceacam12 |
T |
A |
7: 17,811,305 (GRCm39) |
|
probably null |
Het |
| Cfap65 |
C |
A |
1: 74,956,454 (GRCm39) |
V1042F |
possibly damaging |
Het |
| Cfap77 |
T |
C |
2: 28,875,844 (GRCm39) |
I89V |
probably benign |
Het |
| Cfh |
T |
C |
1: 140,014,125 (GRCm39) |
D688G |
probably benign |
Het |
| Clip1 |
C |
G |
5: 123,721,664 (GRCm39) |
A1182P |
probably damaging |
Het |
| Cyp2b10 |
T |
A |
7: 25,614,921 (GRCm39) |
Y309* |
probably null |
Het |
| Dcaf5 |
T |
C |
12: 80,385,858 (GRCm39) |
E756G |
probably benign |
Het |
| Dctn1 |
A |
T |
6: 83,176,753 (GRCm39) |
Q1231L |
possibly damaging |
Het |
| Dennd1c |
T |
A |
17: 57,373,428 (GRCm39) |
R682* |
probably null |
Het |
| Eml6 |
C |
A |
11: 29,727,052 (GRCm39) |
E1319* |
probably null |
Het |
| Erap1 |
T |
C |
13: 74,838,766 (GRCm39) |
I904T |
probably damaging |
Het |
| Eri1 |
A |
T |
8: 35,943,673 (GRCm39) |
I207N |
possibly damaging |
Het |
| Farp1 |
G |
A |
14: 121,514,469 (GRCm39) |
A933T |
probably damaging |
Het |
| Fcna |
T |
A |
2: 25,515,353 (GRCm39) |
Q210L |
probably benign |
Het |
| Fhad1 |
A |
T |
4: 141,643,378 (GRCm39) |
|
probably null |
Het |
| Fut8 |
T |
G |
12: 77,440,603 (GRCm39) |
Y197D |
probably damaging |
Het |
| Garem1 |
G |
A |
18: 21,262,825 (GRCm39) |
T663I |
probably benign |
Het |
| Gfm2 |
T |
C |
13: 97,301,546 (GRCm39) |
S450P |
probably damaging |
Het |
| Gstk1 |
T |
G |
6: 42,222,938 (GRCm39) |
|
probably benign |
Het |
| Helz2 |
C |
T |
2: 180,879,210 (GRCm39) |
A803T |
probably damaging |
Het |
| Igsf9 |
T |
A |
1: 172,319,455 (GRCm39) |
I280N |
probably damaging |
Het |
| Klhl10 |
A |
G |
11: 100,336,669 (GRCm39) |
K219E |
probably benign |
Het |
| L3mbtl4 |
T |
A |
17: 68,768,558 (GRCm39) |
V222D |
probably damaging |
Het |
| Lrrc9 |
A |
T |
12: 72,546,453 (GRCm39) |
N1214Y |
probably damaging |
Het |
| Ltbp2 |
C |
T |
12: 84,840,414 (GRCm39) |
E1051K |
possibly damaging |
Het |
| Mettl17 |
T |
C |
14: 52,122,440 (GRCm39) |
F13S |
probably benign |
Het |
| Mettl24 |
C |
A |
10: 40,559,413 (GRCm39) |
A21D |
possibly damaging |
Het |
| Mfsd6l |
T |
A |
11: 68,447,331 (GRCm39) |
C61S |
probably benign |
Het |
| Mob4 |
T |
G |
1: 55,191,899 (GRCm39) |
D204E |
probably benign |
Het |
| Nlrp4a |
T |
A |
7: 26,149,844 (GRCm39) |
F484I |
possibly damaging |
Het |
| Nsrp1 |
T |
C |
11: 76,941,444 (GRCm39) |
N88S |
probably benign |
Het |
| Odad2 |
G |
T |
18: 7,222,564 (GRCm39) |
H568Q |
possibly damaging |
Het |
| Or10d5 |
C |
T |
9: 39,861,408 (GRCm39) |
V220I |
probably benign |
Het |
| Or2g25 |
T |
A |
17: 37,970,969 (GRCm39) |
H85L |
probably benign |
Het |
| Or51b6b |
T |
C |
7: 103,309,678 (GRCm39) |
T260A |
probably benign |
Het |
| Or6c2 |
T |
A |
10: 129,362,449 (GRCm39) |
Y118N |
probably damaging |
Het |
| Parg |
A |
G |
14: 31,924,408 (GRCm39) |
N69S |
probably benign |
Het |
| Pcdh9 |
A |
C |
14: 94,125,377 (GRCm39) |
N264K |
probably damaging |
Het |
| Pcdhb22 |
G |
T |
18: 37,653,615 (GRCm39) |
L694F |
probably damaging |
Het |
| Pcnt |
T |
C |
10: 76,248,335 (GRCm39) |
E928G |
probably damaging |
Het |
| Pdzk1 |
G |
A |
3: 96,775,751 (GRCm39) |
G373D |
probably benign |
Het |
| Pea15a |
A |
G |
1: 172,026,740 (GRCm39) |
I89T |
probably damaging |
Het |
| Phc1 |
T |
A |
6: 122,313,964 (GRCm39) |
|
probably benign |
Het |
| Pikfyve |
T |
A |
1: 65,235,900 (GRCm39) |
C191S |
probably damaging |
Het |
| Pitpnm1 |
T |
A |
19: 4,158,130 (GRCm39) |
D573E |
probably damaging |
Het |
| Pld5 |
A |
G |
1: 176,102,450 (GRCm39) |
|
probably benign |
Het |
| Plscr2 |
A |
T |
9: 92,173,130 (GRCm39) |
N89I |
possibly damaging |
Het |
| Pm20d2 |
A |
C |
4: 33,179,293 (GRCm39) |
N315K |
probably damaging |
Het |
| Pnpla1 |
T |
A |
17: 29,097,518 (GRCm39) |
M228K |
probably benign |
Het |
| Prim2 |
T |
C |
1: 33,709,217 (GRCm39) |
|
probably benign |
Het |
| Ralgapa2 |
A |
G |
2: 146,246,987 (GRCm39) |
|
probably benign |
Het |
| Rgs22 |
G |
T |
15: 36,050,294 (GRCm39) |
H719N |
probably benign |
Het |
| Ror2 |
C |
T |
13: 53,272,880 (GRCm39) |
D250N |
probably damaging |
Het |
| Saal1 |
A |
G |
7: 46,349,071 (GRCm39) |
V281A |
probably benign |
Het |
| Selenof |
A |
T |
3: 144,296,411 (GRCm39) |
K94N |
probably damaging |
Het |
| Slamf9 |
T |
A |
1: 172,304,831 (GRCm39) |
C148* |
probably null |
Het |
| Slc4a7 |
T |
C |
14: 14,772,699 (GRCm38) |
|
probably null |
Het |
| Slco1a5 |
A |
G |
6: 142,180,431 (GRCm39) |
I657T |
probably benign |
Het |
| St3gal2 |
A |
T |
8: 111,684,480 (GRCm39) |
H46L |
probably benign |
Het |
| Sucnr1 |
T |
G |
3: 59,994,069 (GRCm39) |
M199R |
probably damaging |
Het |
| Taok1 |
T |
A |
11: 77,444,500 (GRCm39) |
E525V |
probably null |
Het |
| Tbc1d10c |
T |
A |
19: 4,235,445 (GRCm39) |
E298V |
probably damaging |
Het |
| Tll2 |
T |
A |
19: 41,118,951 (GRCm39) |
H259L |
probably damaging |
Het |
| Tpcn1 |
A |
T |
5: 120,691,554 (GRCm39) |
F300Y |
probably damaging |
Het |
| Uba6 |
T |
A |
5: 86,279,197 (GRCm39) |
I642L |
probably benign |
Het |
| Ubqln5 |
T |
A |
7: 103,778,829 (GRCm39) |
|
probably benign |
Het |
| Vmn1r27 |
A |
T |
6: 58,192,827 (GRCm39) |
L9Q |
possibly damaging |
Het |
| Vmn2r100 |
C |
T |
17: 19,741,672 (GRCm39) |
T128I |
probably benign |
Het |
| Vmn2r109 |
C |
T |
17: 20,761,494 (GRCm39) |
G621D |
probably benign |
Het |
| Vmn2r49 |
C |
T |
7: 9,720,352 (GRCm39) |
D380N |
probably benign |
Het |
| Vps13a |
C |
T |
19: 16,655,356 (GRCm39) |
V1891I |
probably benign |
Het |
| Wbp2 |
G |
T |
11: 115,971,463 (GRCm39) |
Y147* |
probably null |
Het |
| Wdr46 |
T |
A |
17: 34,160,810 (GRCm39) |
N191K |
probably benign |
Het |
| Wdr46 |
T |
C |
17: 34,168,373 (GRCm39) |
|
probably benign |
Het |
| Wnt2 |
A |
C |
6: 18,023,285 (GRCm39) |
F121L |
probably benign |
Het |
| Xpnpep1 |
T |
A |
19: 53,003,053 (GRCm39) |
D100V |
probably benign |
Het |
| Xpo4 |
T |
C |
14: 57,827,559 (GRCm39) |
Y879C |
probably damaging |
Het |
| Zswim4 |
A |
T |
8: 84,938,948 (GRCm39) |
V978D |
probably damaging |
Het |
|
| Other mutations in Mtus1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00708:Mtus1
|
APN |
8 |
41,537,386 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01377:Mtus1
|
APN |
8 |
41,536,172 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01472:Mtus1
|
APN |
8 |
41,455,449 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01995:Mtus1
|
APN |
8 |
41,537,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02027:Mtus1
|
APN |
8 |
41,446,638 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02381:Mtus1
|
APN |
8 |
41,536,156 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL02571:Mtus1
|
APN |
8 |
41,536,519 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02936:Mtus1
|
APN |
8 |
41,452,554 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0116:Mtus1
|
UTSW |
8 |
41,451,514 (GRCm39) |
unclassified |
probably benign |
|
|
R0139:Mtus1
|
UTSW |
8 |
41,469,233 (GRCm39) |
splice site |
probably benign |
|
|
R0178:Mtus1
|
UTSW |
8 |
41,455,398 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0179:Mtus1
|
UTSW |
8 |
41,455,398 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0220:Mtus1
|
UTSW |
8 |
41,447,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0324:Mtus1
|
UTSW |
8 |
41,537,432 (GRCm39) |
missense |
probably benign |
|
|
R0355:Mtus1
|
UTSW |
8 |
41,535,965 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0357:Mtus1
|
UTSW |
8 |
41,536,563 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R0464:Mtus1
|
UTSW |
8 |
41,455,511 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0681:Mtus1
|
UTSW |
8 |
41,446,554 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1016:Mtus1
|
UTSW |
8 |
41,503,063 (GRCm39) |
missense |
probably benign |
0.43 |
|
R1570:Mtus1
|
UTSW |
8 |
41,529,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1579:Mtus1
|
UTSW |
8 |
41,535,895 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1607:Mtus1
|
UTSW |
8 |
41,468,446 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1869:Mtus1
|
UTSW |
8 |
41,529,267 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1888:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1888:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1891:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1894:Mtus1
|
UTSW |
8 |
41,537,362 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2063:Mtus1
|
UTSW |
8 |
41,535,745 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2111:Mtus1
|
UTSW |
8 |
41,475,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2112:Mtus1
|
UTSW |
8 |
41,475,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2224:Mtus1
|
UTSW |
8 |
41,535,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2226:Mtus1
|
UTSW |
8 |
41,535,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2227:Mtus1
|
UTSW |
8 |
41,535,812 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2516:Mtus1
|
UTSW |
8 |
41,535,776 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3414:Mtus1
|
UTSW |
8 |
41,501,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3899:Mtus1
|
UTSW |
8 |
41,536,166 (GRCm39) |
missense |
probably benign |
|
|
R4096:Mtus1
|
UTSW |
8 |
41,537,284 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4850:Mtus1
|
UTSW |
8 |
41,537,507 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4916:Mtus1
|
UTSW |
8 |
41,453,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4940:Mtus1
|
UTSW |
8 |
41,494,515 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R4988:Mtus1
|
UTSW |
8 |
41,537,578 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5133:Mtus1
|
UTSW |
8 |
41,536,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5468:Mtus1
|
UTSW |
8 |
41,537,615 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5598:Mtus1
|
UTSW |
8 |
41,475,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5782:Mtus1
|
UTSW |
8 |
41,535,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5860:Mtus1
|
UTSW |
8 |
41,529,303 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5900:Mtus1
|
UTSW |
8 |
41,536,534 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5943:Mtus1
|
UTSW |
8 |
41,537,302 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6019:Mtus1
|
UTSW |
8 |
41,536,077 (GRCm39) |
missense |
probably benign |
0.33 |
|
R6125:Mtus1
|
UTSW |
8 |
41,537,576 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6197:Mtus1
|
UTSW |
8 |
41,537,074 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6488:Mtus1
|
UTSW |
8 |
41,494,545 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R6869:Mtus1
|
UTSW |
8 |
41,535,691 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7117:Mtus1
|
UTSW |
8 |
41,536,621 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7126:Mtus1
|
UTSW |
8 |
41,468,439 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7213:Mtus1
|
UTSW |
8 |
41,537,524 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7308:Mtus1
|
UTSW |
8 |
41,535,965 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7424:Mtus1
|
UTSW |
8 |
41,475,443 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7481:Mtus1
|
UTSW |
8 |
41,537,652 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7485:Mtus1
|
UTSW |
8 |
41,537,590 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7660:Mtus1
|
UTSW |
8 |
41,469,248 (GRCm39) |
missense |
probably benign |
|
|
R7699:Mtus1
|
UTSW |
8 |
41,537,006 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7700:Mtus1
|
UTSW |
8 |
41,537,006 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7709:Mtus1
|
UTSW |
8 |
41,507,687 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R7791:Mtus1
|
UTSW |
8 |
41,536,417 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8196:Mtus1
|
UTSW |
8 |
41,509,689 (GRCm39) |
missense |
probably benign |
|
|
R8463:Mtus1
|
UTSW |
8 |
41,536,271 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8724:Mtus1
|
UTSW |
8 |
41,451,500 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9047:Mtus1
|
UTSW |
8 |
41,536,760 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9092:Mtus1
|
UTSW |
8 |
41,455,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9283:Mtus1
|
UTSW |
8 |
41,536,519 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9313:Mtus1
|
UTSW |
8 |
41,535,923 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9329:Mtus1
|
UTSW |
8 |
41,537,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9603:Mtus1
|
UTSW |
8 |
41,536,795 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9711:Mtus1
|
UTSW |
8 |
41,536,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGAATGAGTTGTAACTTGCGCAG -3'
(R):5'- ATGCTAAACGTGCACCAAACTTG -3'
Sequencing Primer
(F):5'- CCTGGCTGGTAATGAGTTTATTAAAC -3'
(R):5'- CGTGCACCAAACTTGAAAGG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation