Incidental Mutation 'R4997:Ttc3'
| ID |
385390 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ttc3
|
| Ensembl Gene |
ENSMUSG00000040785 |
| Gene Name |
tetratricopeptide repeat domain 3 |
| Synonyms |
D16Ium21e, TPRD, 2610202A04Rik, D16Ium21 |
| MMRRC Submission |
042591-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.574)
|
| Stock # |
R4997 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
94171479-94270081 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to G
at 94253841 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glutamic Acid
at position 1221
(D1221E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000156137
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000117648]
[ENSMUST00000154196]
[ENSMUST00000231569]
[ENSMUST00000231915]
[ENSMUST00000232660]
[ENSMUST00000232395]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000117648
AA Change: D1576E
PolyPhen 2
Score 0.855 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000112801
Gene: ENSMUSG00000040785
AA Change: D1576E
| Domain | Start | End | E-Value | Type |
|---|
|
TPR
|
231 |
264 |
3.61e-2 |
SMART |
|
TPR
|
265 |
298 |
3.32e-1 |
SMART |
|
Blast:TPR
|
300 |
332 |
2e-12 |
BLAST |
|
low complexity region
|
444 |
459 |
N/A |
INTRINSIC |
|
TPR
|
576 |
609 |
2.55e-2 |
SMART |
|
low complexity region
|
720 |
732 |
N/A |
INTRINSIC |
|
coiled coil region
|
765 |
796 |
N/A |
INTRINSIC |
|
low complexity region
|
1018 |
1032 |
N/A |
INTRINSIC |
|
low complexity region
|
1036 |
1050 |
N/A |
INTRINSIC |
|
low complexity region
|
1170 |
1190 |
N/A |
INTRINSIC |
|
low complexity region
|
1248 |
1260 |
N/A |
INTRINSIC |
|
low complexity region
|
1278 |
1291 |
N/A |
INTRINSIC |
|
coiled coil region
|
1472 |
1570 |
N/A |
INTRINSIC |
|
low complexity region
|
1876 |
1887 |
N/A |
INTRINSIC |
|
RING
|
1931 |
1970 |
7e-9 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139607
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000141192
AA Change: D17E
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000154196
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000231569
AA Change: D1221E
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000231915
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000232368
AA Change: D200E
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000232660
AA Change: D1576E
PolyPhen 2
Score 0.855 (Sensitivity: 0.83; Specificity: 0.93)
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000232395
AA Change: D1576E
PolyPhen 2
Score 0.855 (Sensitivity: 0.83; Specificity: 0.93)
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.1%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A630023A22Rik |
A |
T |
14: 33,775,623 (GRCm39) |
M1L |
probably benign |
Het |
| Abca7 |
C |
A |
10: 79,843,154 (GRCm39) |
Q1210K |
possibly damaging |
Het |
| Abcc4 |
C |
T |
14: 118,753,915 (GRCm39) |
W1024* |
probably null |
Het |
| Accs |
A |
T |
2: 93,672,228 (GRCm39) |
Y213* |
probably null |
Het |
| Adam6a |
G |
T |
12: 113,508,991 (GRCm39) |
G455C |
probably damaging |
Het |
| Adcy1 |
A |
C |
11: 7,111,298 (GRCm39) |
Y863S |
probably benign |
Het |
| Adgrg1 |
A |
G |
8: 95,736,148 (GRCm39) |
D434G |
probably damaging |
Het |
| Afap1l1 |
C |
T |
18: 61,884,879 (GRCm39) |
R202Q |
probably benign |
Het |
| Aldh3a1 |
T |
C |
11: 61,103,137 (GRCm39) |
V27A |
probably benign |
Het |
| Antxr2 |
A |
G |
5: 98,125,553 (GRCm39) |
F235L |
probably benign |
Het |
| Arhgap23 |
T |
A |
11: 97,342,846 (GRCm39) |
V376E |
probably damaging |
Het |
| Brca1 |
A |
C |
11: 101,415,159 (GRCm39) |
S992A |
probably damaging |
Het |
| Brcc3dc |
A |
G |
10: 108,535,649 (GRCm39) |
I102T |
probably benign |
Het |
| Calcrl |
A |
T |
2: 84,181,592 (GRCm39) |
C185* |
probably null |
Het |
| Cep152 |
T |
C |
2: 125,428,271 (GRCm39) |
T787A |
probably benign |
Het |
| Coch |
T |
A |
12: 51,649,964 (GRCm39) |
|
probably null |
Het |
| Col5a1 |
T |
A |
2: 27,922,794 (GRCm39) |
Y287* |
probably null |
Het |
| Dis3l |
A |
G |
9: 64,219,224 (GRCm39) |
S569P |
possibly damaging |
Het |
| Dnai1 |
A |
G |
4: 41,597,919 (GRCm39) |
I74V |
possibly damaging |
Het |
| Dpy19l4 |
A |
G |
4: 11,287,493 (GRCm39) |
V394A |
probably benign |
Het |
| Egfem1 |
A |
G |
3: 29,207,739 (GRCm39) |
H122R |
probably benign |
Het |
| Endou |
A |
G |
15: 97,617,458 (GRCm39) |
L164P |
probably damaging |
Het |
| Epgn |
A |
G |
5: 91,180,098 (GRCm39) |
E80G |
possibly damaging |
Het |
| Fcgbpl1 |
T |
G |
7: 27,843,349 (GRCm39) |
S746A |
possibly damaging |
Het |
| Fitm1 |
T |
C |
14: 55,814,364 (GRCm39) |
S287P |
probably benign |
Het |
| Foxm1 |
A |
G |
6: 128,342,731 (GRCm39) |
N22D |
probably benign |
Het |
| Gsdmc |
A |
T |
15: 63,648,629 (GRCm39) |
M426K |
probably damaging |
Het |
| Hmcn2 |
T |
A |
2: 31,291,720 (GRCm39) |
V2418D |
probably damaging |
Het |
| Hs3st2 |
T |
A |
7: 121,099,679 (GRCm39) |
L175Q |
possibly damaging |
Het |
| Il1r2 |
T |
C |
1: 40,160,206 (GRCm39) |
|
probably null |
Het |
| Il27ra |
A |
T |
8: 84,766,156 (GRCm39) |
Y209* |
probably null |
Het |
| Inpp5a |
A |
T |
7: 138,980,654 (GRCm39) |
S31C |
probably benign |
Het |
| Invs |
A |
G |
4: 48,396,332 (GRCm39) |
D335G |
probably damaging |
Het |
| Isg15 |
C |
T |
4: 156,284,154 (GRCm39) |
E125K |
possibly damaging |
Het |
| Klk14 |
G |
A |
7: 43,341,501 (GRCm39) |
C51Y |
probably damaging |
Het |
| Lama4 |
C |
A |
10: 38,968,262 (GRCm39) |
T1468K |
probably damaging |
Het |
| Lce1a2 |
A |
G |
3: 92,576,395 (GRCm39) |
S56P |
unknown |
Het |
| Llgl1 |
C |
T |
11: 60,600,394 (GRCm39) |
P581L |
probably benign |
Het |
| Lmf1 |
G |
A |
17: 25,807,650 (GRCm39) |
W164* |
probably null |
Het |
| Mad2l1bp |
G |
T |
17: 46,463,804 (GRCm39) |
C73* |
probably null |
Het |
| Mpzl1 |
A |
C |
1: 165,429,350 (GRCm39) |
V230G |
probably damaging |
Het |
| Myo3b |
A |
G |
2: 70,088,427 (GRCm39) |
T869A |
possibly damaging |
Het |
| Ncor2 |
T |
C |
5: 125,111,074 (GRCm39) |
H1316R |
probably damaging |
Het |
| Nlrp1b |
T |
A |
11: 71,109,160 (GRCm39) |
I114F |
probably damaging |
Het |
| Nsun7 |
A |
G |
5: 66,453,182 (GRCm39) |
I632M |
probably benign |
Het |
| Nubp1 |
T |
C |
16: 10,239,185 (GRCm39) |
I234T |
probably benign |
Het |
| Olfml1 |
A |
G |
7: 107,170,413 (GRCm39) |
D100G |
probably damaging |
Het |
| Or1e1b-ps1 |
T |
A |
11: 73,845,612 (GRCm39) |
L32Q |
probably damaging |
Het |
| Or5p73 |
C |
A |
7: 108,064,701 (GRCm39) |
Q57K |
probably benign |
Het |
| Or7g23 |
A |
T |
9: 19,086,627 (GRCm39) |
L115Q |
probably damaging |
Het |
| Osmr |
G |
T |
15: 6,845,120 (GRCm39) |
P882Q |
probably benign |
Het |
| Peg10 |
TCAGGATCC |
TCAGGATCCCCAGCAGGATCC |
6: 4,756,457 (GRCm39) |
|
probably benign |
Het |
| Per2 |
T |
A |
1: 91,378,505 (GRCm39) |
T15S |
probably benign |
Het |
| Piezo2 |
A |
G |
18: 63,216,184 (GRCm39) |
Y1184H |
probably damaging |
Het |
| Pik3c2b |
C |
T |
1: 133,032,819 (GRCm39) |
A1560V |
probably damaging |
Het |
| Pik3cd |
A |
C |
4: 149,743,441 (GRCm39) |
L256R |
probably damaging |
Het |
| Ppl |
C |
A |
16: 4,907,235 (GRCm39) |
R1020L |
probably damaging |
Het |
| Ppp1r10 |
A |
G |
17: 36,234,976 (GRCm39) |
N60S |
probably damaging |
Het |
| Prkcg |
T |
C |
7: 3,371,097 (GRCm39) |
|
probably null |
Het |
| Prkci |
T |
C |
3: 31,085,375 (GRCm39) |
|
probably null |
Het |
| Prrc2b |
A |
G |
2: 32,112,323 (GRCm39) |
Y1929C |
probably damaging |
Het |
| Prss12 |
T |
C |
3: 123,240,857 (GRCm39) |
V17A |
probably benign |
Het |
| Qtrt1 |
A |
G |
9: 21,328,654 (GRCm39) |
N206S |
probably benign |
Het |
| Rad54l2 |
A |
C |
9: 106,600,108 (GRCm39) |
S50A |
possibly damaging |
Het |
| Rhov |
C |
T |
2: 119,100,949 (GRCm39) |
R96H |
probably damaging |
Het |
| Rph3a |
A |
T |
5: 121,101,906 (GRCm39) |
V110E |
probably damaging |
Het |
| Rufy4 |
T |
C |
1: 74,186,822 (GRCm39) |
C537R |
probably damaging |
Het |
| Ryr2 |
A |
T |
13: 11,610,192 (GRCm39) |
N646K |
probably benign |
Het |
| Scn8a |
A |
G |
15: 100,854,935 (GRCm39) |
T141A |
probably damaging |
Het |
| Serping1 |
T |
C |
2: 84,600,629 (GRCm39) |
R238G |
possibly damaging |
Het |
| Shank3 |
T |
A |
15: 89,433,901 (GRCm39) |
W1474R |
probably damaging |
Het |
| Slc16a12 |
T |
A |
19: 34,652,358 (GRCm39) |
M263L |
probably benign |
Het |
| Spata13 |
T |
C |
14: 60,946,908 (GRCm39) |
V652A |
probably damaging |
Het |
| Spata31 |
G |
A |
13: 65,067,537 (GRCm39) |
M66I |
probably benign |
Het |
| Spem2 |
T |
C |
11: 69,708,558 (GRCm39) |
I136V |
probably benign |
Het |
| Supt5 |
T |
C |
7: 28,015,462 (GRCm39) |
H925R |
probably benign |
Het |
| Syk |
A |
T |
13: 52,766,484 (GRCm39) |
K190* |
probably null |
Het |
| Thsd1 |
T |
A |
8: 22,733,340 (GRCm39) |
V129D |
probably damaging |
Het |
| Tiprl |
A |
G |
1: 165,047,759 (GRCm39) |
V174A |
possibly damaging |
Het |
| Tmed4 |
T |
A |
11: 6,224,500 (GRCm39) |
|
probably null |
Het |
| Tnfrsf19 |
T |
C |
14: 61,208,658 (GRCm39) |
T288A |
probably benign |
Het |
| Tnfrsf25 |
T |
C |
4: 152,202,153 (GRCm39) |
|
probably null |
Het |
| Tpd52 |
A |
G |
3: 9,000,056 (GRCm39) |
L121S |
probably damaging |
Het |
| Trim30a |
T |
A |
7: 104,060,827 (GRCm39) |
K316N |
probably benign |
Het |
| Ttn |
C |
T |
2: 76,714,403 (GRCm39) |
|
probably benign |
Het |
| Ttn |
T |
C |
2: 76,776,615 (GRCm39) |
I1514V |
probably benign |
Het |
| Ulk2 |
T |
C |
11: 61,689,982 (GRCm39) |
T671A |
probably benign |
Het |
| Wasf1 |
C |
T |
10: 40,810,600 (GRCm39) |
P281S |
probably damaging |
Het |
| Wnt10b |
C |
A |
15: 98,672,084 (GRCm39) |
R211L |
probably damaging |
Het |
| Xpnpep3 |
T |
A |
15: 81,332,577 (GRCm39) |
C371* |
probably null |
Het |
| Zfp41 |
C |
T |
15: 75,490,617 (GRCm39) |
|
probably benign |
Het |
| Zfp553 |
T |
A |
7: 126,834,683 (GRCm39) |
N79K |
probably benign |
Het |
| Zmynd8 |
G |
T |
2: 165,634,736 (GRCm39) |
D1096E |
probably benign |
Het |
|
| Other mutations in Ttc3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00944:Ttc3
|
APN |
16 |
94,227,620 (GRCm39) |
splice site |
probably null |
|
|
IGL00979:Ttc3
|
APN |
16 |
94,257,577 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01520:Ttc3
|
APN |
16 |
94,191,066 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01663:Ttc3
|
APN |
16 |
94,210,590 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01720:Ttc3
|
APN |
16 |
94,186,228 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01736:Ttc3
|
APN |
16 |
94,243,386 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02045:Ttc3
|
APN |
16 |
94,210,540 (GRCm39) |
splice site |
probably benign |
|
|
IGL02203:Ttc3
|
APN |
16 |
94,219,457 (GRCm39) |
splice site |
probably benign |
|
|
IGL02327:Ttc3
|
APN |
16 |
94,248,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02794:Ttc3
|
APN |
16 |
94,268,785 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02898:Ttc3
|
APN |
16 |
94,220,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4378001:Ttc3
|
UTSW |
16 |
94,211,765 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0064:Ttc3
|
UTSW |
16 |
94,223,106 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R0098:Ttc3
|
UTSW |
16 |
94,191,124 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0112:Ttc3
|
UTSW |
16 |
94,186,181 (GRCm39) |
splice site |
probably benign |
|
|
R0135:Ttc3
|
UTSW |
16 |
94,263,127 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0480:Ttc3
|
UTSW |
16 |
94,232,863 (GRCm39) |
nonsense |
probably null |
|
|
R0513:Ttc3
|
UTSW |
16 |
94,227,071 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0532:Ttc3
|
UTSW |
16 |
94,188,189 (GRCm39) |
splice site |
probably benign |
|
|
R0607:Ttc3
|
UTSW |
16 |
94,257,644 (GRCm39) |
nonsense |
probably null |
|
|
R0742:Ttc3
|
UTSW |
16 |
94,260,739 (GRCm39) |
missense |
probably benign |
0.23 |
|
R0905:Ttc3
|
UTSW |
16 |
94,257,648 (GRCm39) |
nonsense |
probably null |
|
|
R1118:Ttc3
|
UTSW |
16 |
94,217,127 (GRCm39) |
splice site |
probably benign |
|
|
R1355:Ttc3
|
UTSW |
16 |
94,219,496 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1370:Ttc3
|
UTSW |
16 |
94,219,496 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1486:Ttc3
|
UTSW |
16 |
94,248,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1598:Ttc3
|
UTSW |
16 |
94,223,156 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1641:Ttc3
|
UTSW |
16 |
94,244,176 (GRCm39) |
missense |
probably benign |
0.19 |
|
R2092:Ttc3
|
UTSW |
16 |
94,243,691 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2232:Ttc3
|
UTSW |
16 |
94,260,831 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2339:Ttc3
|
UTSW |
16 |
94,232,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2342:Ttc3
|
UTSW |
16 |
94,232,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2842:Ttc3
|
UTSW |
16 |
94,232,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3117:Ttc3
|
UTSW |
16 |
94,243,422 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4194:Ttc3
|
UTSW |
16 |
94,223,136 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4329:Ttc3
|
UTSW |
16 |
94,267,820 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4431:Ttc3
|
UTSW |
16 |
94,211,817 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4530:Ttc3
|
UTSW |
16 |
94,267,736 (GRCm39) |
intron |
probably benign |
|
|
R4531:Ttc3
|
UTSW |
16 |
94,267,736 (GRCm39) |
intron |
probably benign |
|
|
R4532:Ttc3
|
UTSW |
16 |
94,267,736 (GRCm39) |
intron |
probably benign |
|
|
R4533:Ttc3
|
UTSW |
16 |
94,267,736 (GRCm39) |
intron |
probably benign |
|
|
R4588:Ttc3
|
UTSW |
16 |
94,243,760 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4625:Ttc3
|
UTSW |
16 |
94,189,131 (GRCm39) |
nonsense |
probably null |
|
|
R4676:Ttc3
|
UTSW |
16 |
94,243,620 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4700:Ttc3
|
UTSW |
16 |
94,240,100 (GRCm39) |
splice site |
probably null |
|
|
R4856:Ttc3
|
UTSW |
16 |
94,191,142 (GRCm39) |
missense |
probably benign |
0.32 |
|
R4867:Ttc3
|
UTSW |
16 |
94,255,374 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4885:Ttc3
|
UTSW |
16 |
94,227,690 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4885:Ttc3
|
UTSW |
16 |
94,220,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4899:Ttc3
|
UTSW |
16 |
94,230,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5023:Ttc3
|
UTSW |
16 |
94,230,218 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5105:Ttc3
|
UTSW |
16 |
94,267,793 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5205:Ttc3
|
UTSW |
16 |
94,248,918 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5287:Ttc3
|
UTSW |
16 |
94,260,703 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5338:Ttc3
|
UTSW |
16 |
94,184,900 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5347:Ttc3
|
UTSW |
16 |
94,230,479 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5403:Ttc3
|
UTSW |
16 |
94,260,703 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5460:Ttc3
|
UTSW |
16 |
94,258,241 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5739:Ttc3
|
UTSW |
16 |
94,240,183 (GRCm39) |
nonsense |
probably null |
|
|
R6242:Ttc3
|
UTSW |
16 |
94,243,554 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6253:Ttc3
|
UTSW |
16 |
94,258,272 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6455:Ttc3
|
UTSW |
16 |
94,219,482 (GRCm39) |
start codon destroyed |
probably null |
0.83 |
|
R6559:Ttc3
|
UTSW |
16 |
94,223,208 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6564:Ttc3
|
UTSW |
16 |
94,243,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6932:Ttc3
|
UTSW |
16 |
94,244,312 (GRCm39) |
missense |
probably benign |
|
|
R7331:Ttc3
|
UTSW |
16 |
94,195,218 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7497:Ttc3
|
UTSW |
16 |
94,219,541 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7610:Ttc3
|
UTSW |
16 |
94,228,697 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7738:Ttc3
|
UTSW |
16 |
94,188,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7970:Ttc3
|
UTSW |
16 |
94,258,223 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8052:Ttc3
|
UTSW |
16 |
94,268,848 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8087:Ttc3
|
UTSW |
16 |
94,243,812 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8309:Ttc3
|
UTSW |
16 |
94,267,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8320:Ttc3
|
UTSW |
16 |
94,219,535 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8322:Ttc3
|
UTSW |
16 |
94,255,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8518:Ttc3
|
UTSW |
16 |
94,258,238 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8670:Ttc3
|
UTSW |
16 |
94,191,067 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8826:Ttc3
|
UTSW |
16 |
94,232,829 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8868:Ttc3
|
UTSW |
16 |
94,252,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8873:Ttc3
|
UTSW |
16 |
94,243,842 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8940:Ttc3
|
UTSW |
16 |
94,230,358 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8993:Ttc3
|
UTSW |
16 |
94,228,667 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R9068:Ttc3
|
UTSW |
16 |
94,204,219 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9119:Ttc3
|
UTSW |
16 |
94,192,950 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9124:Ttc3
|
UTSW |
16 |
94,236,389 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9129:Ttc3
|
UTSW |
16 |
94,185,208 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9189:Ttc3
|
UTSW |
16 |
94,268,831 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9217:Ttc3
|
UTSW |
16 |
94,230,467 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9490:Ttc3
|
UTSW |
16 |
94,245,360 (GRCm39) |
missense |
probably benign |
|
|
R9564:Ttc3
|
UTSW |
16 |
94,248,918 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9631:Ttc3
|
UTSW |
16 |
94,171,581 (GRCm39) |
intron |
probably benign |
|
|
X0022:Ttc3
|
UTSW |
16 |
94,243,384 (GRCm39) |
missense |
probably benign |
0.00 |
|
Y5378:Ttc3
|
UTSW |
16 |
94,212,988 (GRCm39) |
splice site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGCTTCTGTCATCGCCAGTG -3'
(R):5'- TGCTGCCACTAAGTCACACC -3'
Sequencing Primer
(F):5'- GCCAGTGGCCCTATATGTAACTG -3'
(R):5'- TTGAAAGCCAGCCTGGTCTAC -3'
|
| Posted On |
2016-05-10 |
Incidental Mutation