Incidental Mutation 'R5062:Zfp646'
| ID |
386691 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp646
|
| Ensembl Gene |
ENSMUSG00000049739 |
| Gene Name |
zinc finger protein 646 |
| Synonyms |
|
| MMRRC Submission |
042652-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.251)
|
| Stock # |
R5062 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
127476081-127485168 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 127479671 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Histidine
at position 616
(R616H)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000052641
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000050383]
[ENSMUST00000054415]
[ENSMUST00000106261]
[ENSMUST00000106262]
[ENSMUST00000106263]
[ENSMUST00000131000]
[ENSMUST00000144721]
|
| AlphaFold |
Q6NV66 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000050383
AA Change: R616H
PolyPhen 2
Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000052641
Gene: ENSMUSG00000049739
AA Change: R616H
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
8 |
31 |
1.36e-2 |
SMART |
|
ZnF_C2H2
|
67 |
89 |
5.29e-5 |
SMART |
|
ZnF_C2H2
|
231 |
253 |
3.21e-4 |
SMART |
|
ZnF_C2H2
|
258 |
280 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
286 |
308 |
2.24e-3 |
SMART |
|
low complexity region
|
345 |
362 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
366 |
388 |
5.42e-2 |
SMART |
|
ZnF_C2H2
|
393 |
415 |
8.34e-3 |
SMART |
|
ZnF_C2H2
|
457 |
479 |
5.9e-3 |
SMART |
|
ZnF_C2H2
|
484 |
506 |
4.87e-4 |
SMART |
|
ZnF_C2H2
|
566 |
588 |
2.32e-1 |
SMART |
|
ZnF_C2H2
|
606 |
628 |
6.32e-3 |
SMART |
|
ZnF_C2H2
|
633 |
655 |
1.53e-1 |
SMART |
|
low complexity region
|
737 |
750 |
N/A |
INTRINSIC |
|
low complexity region
|
786 |
797 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
806 |
828 |
2.17e-1 |
SMART |
|
ZnF_C2H2
|
833 |
855 |
3.69e-4 |
SMART |
|
ZnF_C2H2
|
866 |
889 |
1.16e-1 |
SMART |
|
low complexity region
|
890 |
911 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
941 |
961 |
9.31e1 |
SMART |
|
ZnF_C2H2
|
1035 |
1057 |
1.95e-3 |
SMART |
|
ZnF_C2H2
|
1062 |
1084 |
3.39e-3 |
SMART |
|
low complexity region
|
1149 |
1163 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
1170 |
1192 |
1.58e-3 |
SMART |
|
ZnF_C2H2
|
1197 |
1219 |
5.42e-2 |
SMART |
|
ZnF_C2H2
|
1225 |
1247 |
3.69e-4 |
SMART |
|
ZnF_C2H2
|
1266 |
1286 |
5.12e1 |
SMART |
|
ZnF_C2H2
|
1293 |
1315 |
3.69e-4 |
SMART |
|
ZnF_C2H2
|
1333 |
1355 |
3.11e-2 |
SMART |
|
ZnF_C2H2
|
1550 |
1572 |
5.9e-3 |
SMART |
|
ZnF_C2H2
|
1640 |
1662 |
1.08e-1 |
SMART |
|
ZnF_C2H2
|
1667 |
1689 |
4.11e-2 |
SMART |
|
ZnF_C2H2
|
1695 |
1717 |
4.11e-2 |
SMART |
|
ZnF_C2H2
|
1724 |
1746 |
1.45e-2 |
SMART |
|
low complexity region
|
1751 |
1764 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000054415
|
| SMART Domains |
Protein: ENSMUSP00000056105
Gene: ENSMUSG00000049728
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
22 |
44 |
7.67e-2 |
SMART |
|
ZnF_C2H2
|
84 |
106 |
9.44e-2 |
SMART |
|
ZnF_C2H2
|
112 |
134 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
140 |
162 |
2.36e-2 |
SMART |
|
ZnF_C2H2
|
168 |
190 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
196 |
218 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
224 |
246 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
252 |
274 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
280 |
302 |
2.57e-3 |
SMART |
|
ZnF_C2H2
|
308 |
330 |
5.59e-4 |
SMART |
|
ZnF_C2H2
|
336 |
358 |
1.79e-2 |
SMART |
|
ZnF_C2H2
|
364 |
386 |
7.9e-4 |
SMART |
|
ZnF_C2H2
|
392 |
414 |
5.5e-3 |
SMART |
|
low complexity region
|
428 |
470 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
516 |
538 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
544 |
566 |
1.3e-4 |
SMART |
|
ZnF_C2H2
|
572 |
594 |
5.59e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106261
|
| SMART Domains |
Protein: ENSMUSP00000101868
Gene: ENSMUSG00000049728
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
22 |
44 |
7.67e-2 |
SMART |
|
ZnF_C2H2
|
84 |
106 |
9.44e-2 |
SMART |
|
ZnF_C2H2
|
112 |
134 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
140 |
162 |
2.36e-2 |
SMART |
|
ZnF_C2H2
|
168 |
190 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
196 |
218 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
224 |
246 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
252 |
274 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
280 |
302 |
2.57e-3 |
SMART |
|
ZnF_C2H2
|
308 |
330 |
5.59e-4 |
SMART |
|
ZnF_C2H2
|
336 |
358 |
1.79e-2 |
SMART |
|
ZnF_C2H2
|
364 |
386 |
7.9e-4 |
SMART |
|
ZnF_C2H2
|
392 |
414 |
5.5e-3 |
SMART |
|
low complexity region
|
428 |
470 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
516 |
538 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
544 |
566 |
1.3e-4 |
SMART |
|
ZnF_C2H2
|
572 |
594 |
5.59e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106262
|
| SMART Domains |
Protein: ENSMUSP00000101869
Gene: ENSMUSG00000049728
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
22 |
44 |
7.67e-2 |
SMART |
|
ZnF_C2H2
|
84 |
106 |
9.44e-2 |
SMART |
|
ZnF_C2H2
|
112 |
134 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
140 |
162 |
2.36e-2 |
SMART |
|
ZnF_C2H2
|
168 |
190 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
196 |
218 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
224 |
246 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
252 |
274 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
280 |
302 |
2.57e-3 |
SMART |
|
ZnF_C2H2
|
308 |
330 |
5.59e-4 |
SMART |
|
ZnF_C2H2
|
336 |
358 |
1.79e-2 |
SMART |
|
ZnF_C2H2
|
364 |
386 |
7.9e-4 |
SMART |
|
ZnF_C2H2
|
392 |
414 |
5.5e-3 |
SMART |
|
low complexity region
|
428 |
470 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
516 |
538 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
544 |
566 |
1.3e-4 |
SMART |
|
ZnF_C2H2
|
572 |
594 |
5.59e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106263
|
| SMART Domains |
Protein: ENSMUSP00000101870
Gene: ENSMUSG00000049728
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
22 |
44 |
7.67e-2 |
SMART |
|
ZnF_C2H2
|
84 |
106 |
9.44e-2 |
SMART |
|
ZnF_C2H2
|
112 |
134 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
140 |
162 |
2.36e-2 |
SMART |
|
ZnF_C2H2
|
168 |
190 |
1.98e-4 |
SMART |
|
ZnF_C2H2
|
196 |
218 |
2.91e-2 |
SMART |
|
ZnF_C2H2
|
224 |
246 |
1.26e-2 |
SMART |
|
ZnF_C2H2
|
252 |
274 |
5.21e-4 |
SMART |
|
ZnF_C2H2
|
280 |
302 |
2.57e-3 |
SMART |
|
ZnF_C2H2
|
308 |
330 |
5.59e-4 |
SMART |
|
ZnF_C2H2
|
336 |
358 |
1.79e-2 |
SMART |
|
ZnF_C2H2
|
364 |
386 |
7.9e-4 |
SMART |
|
ZnF_C2H2
|
392 |
414 |
5.5e-3 |
SMART |
|
low complexity region
|
428 |
470 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
516 |
538 |
3.63e-3 |
SMART |
|
ZnF_C2H2
|
544 |
566 |
1.3e-4 |
SMART |
|
ZnF_C2H2
|
572 |
594 |
5.59e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131000
|
| SMART Domains |
Protein: ENSMUSP00000115499
Gene: ENSMUSG00000049739
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
8 |
31 |
1.36e-2 |
SMART |
|
ZnF_C2H2
|
67 |
89 |
5.29e-5 |
SMART |
|
ZnF_C2H2
|
231 |
253 |
3.21e-4 |
SMART |
|
ZnF_C2H2
|
258 |
280 |
9.58e-3 |
SMART |
|
ZnF_C2H2
|
286 |
308 |
2.24e-3 |
SMART |
|
low complexity region
|
345 |
362 |
N/A |
INTRINSIC |
|
ZnF_C2H2
|
366 |
388 |
5.42e-2 |
SMART |
|
ZnF_C2H2
|
393 |
415 |
8.34e-3 |
SMART |
|
ZnF_C2H2
|
457 |
479 |
5.9e-3 |
SMART |
|
ZnF_C2H2
|
484 |
506 |
4.87e-4 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000144721
|
| SMART Domains |
Protein: ENSMUSP00000116730
Gene: ENSMUSG00000049728
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
22 |
44 |
7.67e-2 |
SMART |
|
ZnF_C2H2
|
84 |
106 |
9.44e-2 |
SMART |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000206340
AA Change: R396H
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000205364
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150961
|
| Meta Mutation Damage Score |
0.4089 |
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.2%
- 10x: 95.7%
- 20x: 90.1%
|
| Validation Efficiency |
100% (79/79) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 68 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca6 |
A |
T |
11: 110,067,892 (GRCm39) |
I1593N |
probably benign |
Het |
| Akr1b10 |
G |
T |
6: 34,369,041 (GRCm39) |
K173N |
probably damaging |
Het |
| Artn |
A |
T |
4: 117,784,873 (GRCm39) |
L3Q |
probably damaging |
Het |
| Asxl3 |
T |
A |
18: 22,655,775 (GRCm39) |
S1262T |
possibly damaging |
Het |
| Atp6v0a4 |
A |
T |
6: 38,051,118 (GRCm39) |
M420K |
probably benign |
Het |
| Bcam |
T |
A |
7: 19,494,026 (GRCm39) |
T422S |
possibly damaging |
Het |
| Casp2 |
C |
T |
6: 42,246,206 (GRCm39) |
|
probably benign |
Het |
| Ccdc137 |
A |
G |
11: 120,353,341 (GRCm39) |
|
probably benign |
Het |
| Cd177 |
C |
A |
7: 24,443,741 (GRCm39) |
A786S |
probably benign |
Het |
| Cdca4 |
T |
C |
12: 112,785,483 (GRCm39) |
N82D |
probably benign |
Het |
| Clu |
A |
C |
14: 66,217,177 (GRCm39) |
T337P |
probably damaging |
Het |
| Col6a3 |
A |
C |
1: 90,707,074 (GRCm39) |
I2013S |
unknown |
Het |
| Cpne9 |
T |
A |
6: 113,281,449 (GRCm39) |
M510K |
probably damaging |
Het |
| Cyp3a13 |
A |
C |
5: 137,897,161 (GRCm39) |
N384K |
possibly damaging |
Het |
| Fam186a |
A |
C |
15: 99,842,527 (GRCm39) |
I1239S |
possibly damaging |
Het |
| Fryl |
T |
C |
5: 73,233,236 (GRCm39) |
E413G |
possibly damaging |
Het |
| Fscn2 |
A |
C |
11: 120,257,575 (GRCm39) |
Y312S |
probably damaging |
Het |
| Fshr |
A |
T |
17: 89,293,474 (GRCm39) |
C401* |
probably null |
Het |
| Glyat |
A |
C |
19: 12,627,627 (GRCm39) |
Q74P |
probably damaging |
Het |
| Gm6158 |
A |
T |
14: 24,120,158 (GRCm39) |
|
noncoding transcript |
Het |
| Grm7 |
A |
G |
6: 110,623,097 (GRCm39) |
N90S |
probably damaging |
Het |
| Hectd1 |
A |
T |
12: 51,791,662 (GRCm39) |
C2536S |
probably damaging |
Het |
| Herc3 |
C |
T |
6: 58,832,745 (GRCm39) |
Q137* |
probably null |
Het |
| Kctd3 |
A |
C |
1: 188,727,890 (GRCm39) |
|
probably benign |
Het |
| Klhl30 |
A |
G |
1: 91,283,300 (GRCm39) |
T301A |
probably benign |
Het |
| Klra9 |
T |
C |
6: 130,156,072 (GRCm39) |
K228E |
possibly damaging |
Het |
| Lamc3 |
A |
T |
2: 31,795,679 (GRCm39) |
T355S |
possibly damaging |
Het |
| Lcmt1 |
A |
C |
7: 123,010,053 (GRCm39) |
|
probably null |
Het |
| Limch1 |
C |
T |
5: 67,126,578 (GRCm39) |
P60S |
probably damaging |
Het |
| Lrfn2 |
A |
G |
17: 49,377,528 (GRCm39) |
D203G |
probably damaging |
Het |
| Mc5r |
T |
C |
18: 68,472,352 (GRCm39) |
L237P |
probably damaging |
Het |
| Mknk2 |
G |
A |
10: 80,507,603 (GRCm39) |
R58W |
probably damaging |
Het |
| Mrgpra2b |
T |
C |
7: 47,152,676 (GRCm39) |
|
probably benign |
Het |
| Mroh2a |
GCCC |
GC |
1: 88,159,979 (GRCm39) |
|
probably null |
Het |
| Nae1 |
A |
T |
8: 105,243,334 (GRCm39) |
C395S |
possibly damaging |
Het |
| Ncoa1 |
A |
G |
12: 4,309,333 (GRCm39) |
M1321T |
probably damaging |
Het |
| Neb |
A |
C |
2: 52,170,513 (GRCm39) |
F1720V |
possibly damaging |
Het |
| Nectin2 |
C |
T |
7: 19,472,198 (GRCm39) |
V64I |
probably benign |
Het |
| Nisch |
T |
A |
14: 30,894,397 (GRCm39) |
T1145S |
probably damaging |
Het |
| Nlrp5 |
A |
T |
7: 23,135,335 (GRCm39) |
R1009* |
probably null |
Het |
| Or12d13 |
A |
T |
17: 37,647,822 (GRCm39) |
H100Q |
probably damaging |
Het |
| Or4k15 |
T |
A |
14: 50,364,894 (GRCm39) |
Y287N |
probably damaging |
Het |
| Otx1 |
C |
A |
11: 21,947,037 (GRCm39) |
A91S |
probably damaging |
Het |
| Pak1ip1 |
A |
G |
13: 41,161,621 (GRCm39) |
|
probably benign |
Het |
| Pcm1 |
T |
C |
8: 41,712,297 (GRCm39) |
V189A |
probably damaging |
Het |
| Peak1 |
G |
T |
9: 56,167,573 (GRCm39) |
N118K |
probably damaging |
Het |
| Phgdh |
T |
A |
3: 98,235,655 (GRCm39) |
I121F |
probably damaging |
Het |
| Pi4ka |
G |
T |
16: 17,127,261 (GRCm39) |
A1064E |
probably benign |
Het |
| Pkhd1 |
A |
C |
1: 20,655,935 (GRCm39) |
C199W |
probably benign |
Het |
| Plat |
A |
G |
8: 23,262,327 (GRCm39) |
D117G |
probably benign |
Het |
| Ppp2r2b |
C |
A |
18: 42,821,526 (GRCm39) |
V211L |
possibly damaging |
Het |
| Ptgs1 |
A |
G |
2: 36,127,294 (GRCm39) |
D60G |
probably damaging |
Het |
| Ryr2 |
T |
C |
13: 11,715,240 (GRCm39) |
E2776G |
probably damaging |
Het |
| Sema4c |
C |
T |
1: 36,592,059 (GRCm39) |
|
probably null |
Het |
| Sharpin |
T |
C |
15: 76,231,811 (GRCm39) |
|
probably benign |
Het |
| Slamf6 |
A |
G |
1: 171,764,100 (GRCm39) |
I164M |
possibly damaging |
Het |
| Slco1a7 |
A |
C |
6: 141,713,180 (GRCm39) |
M67R |
possibly damaging |
Het |
| Spef1 |
A |
G |
2: 131,015,201 (GRCm39) |
Y46H |
probably damaging |
Het |
| Spns1 |
G |
A |
7: 125,973,501 (GRCm39) |
|
probably benign |
Het |
| Supt5 |
C |
T |
7: 28,028,440 (GRCm39) |
|
probably null |
Het |
| Tbx5 |
T |
A |
5: 119,974,987 (GRCm39) |
D3E |
probably damaging |
Het |
| Thbs1 |
T |
C |
2: 117,951,718 (GRCm39) |
|
probably null |
Het |
| Tmem140 |
G |
A |
6: 34,849,897 (GRCm39) |
V138M |
probably damaging |
Het |
| Tmem200a |
T |
A |
10: 25,869,813 (GRCm39) |
D152V |
probably damaging |
Het |
| Tmem200b |
A |
G |
4: 131,649,848 (GRCm39) |
D256G |
probably damaging |
Het |
| Tns1 |
A |
T |
1: 73,992,023 (GRCm39) |
L885Q |
probably damaging |
Het |
| Umod |
G |
A |
7: 119,071,644 (GRCm39) |
Q366* |
probably null |
Het |
| Vsir |
A |
G |
10: 60,200,042 (GRCm39) |
I208V |
probably damaging |
Het |
|
| Other mutations in Zfp646 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00930:Zfp646
|
APN |
7 |
127,478,302 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01669:Zfp646
|
APN |
7 |
127,478,137 (GRCm39) |
missense |
probably benign |
|
|
IGL02571:Zfp646
|
APN |
7 |
127,478,584 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0009:Zfp646
|
UTSW |
7 |
127,479,903 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0084:Zfp646
|
UTSW |
7 |
127,480,476 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0140:Zfp646
|
UTSW |
7 |
127,482,678 (GRCm39) |
missense |
probably benign |
0.41 |
|
R0394:Zfp646
|
UTSW |
7 |
127,482,434 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0571:Zfp646
|
UTSW |
7 |
127,481,138 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0924:Zfp646
|
UTSW |
7 |
127,482,982 (GRCm39) |
nonsense |
probably null |
|
|
R0930:Zfp646
|
UTSW |
7 |
127,482,982 (GRCm39) |
nonsense |
probably null |
|
|
R1219:Zfp646
|
UTSW |
7 |
127,482,292 (GRCm39) |
missense |
probably benign |
|
|
R1221:Zfp646
|
UTSW |
7 |
127,482,292 (GRCm39) |
missense |
probably benign |
|
|
R1351:Zfp646
|
UTSW |
7 |
127,482,683 (GRCm39) |
missense |
probably benign |
|
|
R1370:Zfp646
|
UTSW |
7 |
127,479,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1503:Zfp646
|
UTSW |
7 |
127,479,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1605:Zfp646
|
UTSW |
7 |
127,479,359 (GRCm39) |
splice site |
probably null |
|
|
R1817:Zfp646
|
UTSW |
7 |
127,482,292 (GRCm39) |
missense |
probably benign |
|
|
R1818:Zfp646
|
UTSW |
7 |
127,482,292 (GRCm39) |
missense |
probably benign |
|
|
R1819:Zfp646
|
UTSW |
7 |
127,482,292 (GRCm39) |
missense |
probably benign |
|
|
R1838:Zfp646
|
UTSW |
7 |
127,478,911 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1870:Zfp646
|
UTSW |
7 |
127,483,021 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2100:Zfp646
|
UTSW |
7 |
127,481,359 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2763:Zfp646
|
UTSW |
7 |
127,479,210 (GRCm39) |
nonsense |
probably null |
|
|
R4346:Zfp646
|
UTSW |
7 |
127,478,681 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4770:Zfp646
|
UTSW |
7 |
127,482,649 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4824:Zfp646
|
UTSW |
7 |
127,482,907 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4936:Zfp646
|
UTSW |
7 |
127,480,933 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4937:Zfp646
|
UTSW |
7 |
127,478,354 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5424:Zfp646
|
UTSW |
7 |
127,481,875 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R5610:Zfp646
|
UTSW |
7 |
127,478,530 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5729:Zfp646
|
UTSW |
7 |
127,484,626 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6112:Zfp646
|
UTSW |
7 |
127,478,190 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6161:Zfp646
|
UTSW |
7 |
127,477,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6310:Zfp646
|
UTSW |
7 |
127,483,079 (GRCm39) |
missense |
probably benign |
0.13 |
|
R6331:Zfp646
|
UTSW |
7 |
127,482,853 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6436:Zfp646
|
UTSW |
7 |
127,479,113 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6814:Zfp646
|
UTSW |
7 |
127,482,505 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6872:Zfp646
|
UTSW |
7 |
127,482,505 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6903:Zfp646
|
UTSW |
7 |
127,479,892 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R7018:Zfp646
|
UTSW |
7 |
127,481,494 (GRCm39) |
missense |
probably benign |
|
|
R7049:Zfp646
|
UTSW |
7 |
127,479,199 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7121:Zfp646
|
UTSW |
7 |
127,478,944 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7405:Zfp646
|
UTSW |
7 |
127,477,968 (GRCm39) |
nonsense |
probably null |
|
|
R8345:Zfp646
|
UTSW |
7 |
127,483,082 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8545:Zfp646
|
UTSW |
7 |
127,484,662 (GRCm39) |
missense |
probably benign |
|
|
R8909:Zfp646
|
UTSW |
7 |
127,478,515 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8983:Zfp646
|
UTSW |
7 |
127,480,777 (GRCm39) |
missense |
probably benign |
|
|
R9001:Zfp646
|
UTSW |
7 |
127,478,856 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9018:Zfp646
|
UTSW |
7 |
127,478,243 (GRCm39) |
missense |
probably benign |
|
|
R9118:Zfp646
|
UTSW |
7 |
127,480,810 (GRCm39) |
missense |
|
|
|
R9414:Zfp646
|
UTSW |
7 |
127,481,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Zfp646
|
UTSW |
7 |
127,479,804 (GRCm39) |
missense |
probably benign |
0.12 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTAACCCCTCAATGGCAGATAG -3'
(R):5'- TTTTCCAGCTTCAGGGTCCAG -3'
Sequencing Primer
(F):5'- CCCTCAATGGCAGATAGGACAGTG -3'
(R):5'- GAGCGTGGCTACTTCCCCTG -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation