Incidental Mutation 'R5022:Myh7b'
| ID |
389224 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh7b
|
| Ensembl Gene |
ENSMUSG00000074652 |
| Gene Name |
myosin, heavy chain 7B, cardiac muscle, beta |
| Synonyms |
Myh14 |
| MMRRC Submission |
042613-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5022 (G1)
|
| Quality Score |
119 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
155453132-155476227 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to C
at 155474293 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Serine
at position 1669
(R1669S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000090672
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041059]
[ENSMUST00000092995]
[ENSMUST00000103140]
|
| AlphaFold |
A2AQP0 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041059
|
| SMART Domains |
Protein: ENSMUSP00000037574
Gene: ENSMUSG00000038324
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
35 |
N/A |
INTRINSIC |
|
low complexity region
|
38 |
53 |
N/A |
INTRINSIC |
|
Pfam:DUF3689
|
407 |
714 |
5.2e-135 |
PFAM |
|
low complexity region
|
724 |
735 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000092995
AA Change: R1669S
PolyPhen 2
Score 0.752 (Sensitivity: 0.85; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000090672
Gene: ENSMUSG00000074652
AA Change: R1669S
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
32 |
72 |
4.7e-14 |
PFAM |
|
MYSc
|
78 |
786 |
N/A |
SMART |
|
IQ
|
787 |
809 |
2.6e0 |
SMART |
|
Pfam:Myosin_tail_1
|
850 |
1931 |
5.5e-149 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000103140
|
| SMART Domains |
Protein: ENSMUSP00000099429
Gene: ENSMUSG00000038324
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
35 |
N/A |
INTRINSIC |
|
low complexity region
|
38 |
53 |
N/A |
INTRINSIC |
|
Pfam:DUF3689
|
399 |
710 |
1.1e-138 |
PFAM |
|
low complexity region
|
716 |
727 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000124415
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143115
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000153246
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154656
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.4%
- 20x: 92.6%
|
| Validation Efficiency |
99% (110/111) |
| MGI Phenotype |
FUNCTION: This gene encodes a myosin heavy chain. The encoded protein forms a hexamer comprised of two heavy chains, two alkali light chains, and two regulatory light chain components. This complex functions in muscle contraction. [provided by RefSeq, Jun 2013]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca1 |
TCGACTGC |
T |
4: 53,041,570 (GRCm39) |
|
probably null |
Het |
| Abca15 |
T |
C |
7: 119,945,319 (GRCm39) |
I465T |
probably damaging |
Het |
| Abca3 |
C |
T |
17: 24,593,274 (GRCm39) |
R224C |
probably damaging |
Het |
| Abcb4 |
T |
A |
5: 8,959,054 (GRCm39) |
|
probably null |
Het |
| Acan |
T |
C |
7: 78,742,556 (GRCm39) |
|
probably null |
Het |
| Aebp2 |
G |
A |
6: 140,583,456 (GRCm39) |
R109Q |
possibly damaging |
Het |
| Agfg2 |
A |
T |
5: 137,658,422 (GRCm39) |
|
probably null |
Het |
| Ankib1 |
T |
A |
5: 3,784,011 (GRCm39) |
I322F |
possibly damaging |
Het |
| AW551984 |
A |
T |
9: 39,509,261 (GRCm39) |
N293K |
probably benign |
Het |
| BC028528 |
T |
A |
3: 95,796,135 (GRCm39) |
|
probably benign |
Het |
| Bicc1 |
A |
G |
10: 70,783,713 (GRCm39) |
S393P |
possibly damaging |
Het |
| Birc6 |
A |
G |
17: 74,999,327 (GRCm39) |
Y4656C |
probably damaging |
Het |
| Bmp3 |
A |
G |
5: 99,020,683 (GRCm39) |
R369G |
probably damaging |
Het |
| C1d |
T |
A |
11: 17,216,674 (GRCm39) |
N135K |
probably benign |
Het |
| Ccdc148 |
G |
A |
2: 58,717,644 (GRCm39) |
A453V |
probably damaging |
Het |
| Cd163 |
C |
T |
6: 124,302,247 (GRCm39) |
T937I |
probably damaging |
Het |
| Celf2 |
C |
T |
2: 6,612,658 (GRCm39) |
|
probably benign |
Het |
| Chga |
T |
C |
12: 102,529,096 (GRCm39) |
W358R |
probably damaging |
Het |
| Clec4b2 |
A |
T |
6: 123,177,915 (GRCm39) |
S77C |
probably null |
Het |
| Crim1 |
T |
C |
17: 78,587,558 (GRCm39) |
V221A |
possibly damaging |
Het |
| D630003M21Rik |
A |
T |
2: 158,059,553 (GRCm39) |
S116T |
probably damaging |
Het |
| Dlg5 |
T |
C |
14: 24,186,690 (GRCm39) |
E1847G |
probably damaging |
Het |
| Dmxl1 |
T |
A |
18: 50,028,194 (GRCm39) |
I2206K |
probably damaging |
Het |
| Dusp7 |
T |
A |
9: 106,250,940 (GRCm39) |
L355Q |
probably damaging |
Het |
| Eif1ad15 |
T |
C |
12: 88,288,071 (GRCm39) |
I61V |
probably benign |
Het |
| Eif1ad16 |
A |
T |
12: 87,985,481 (GRCm39) |
S21T |
unknown |
Het |
| Exd2 |
T |
A |
12: 80,543,564 (GRCm39) |
N582K |
probably damaging |
Het |
| Fbln1 |
G |
A |
15: 85,121,827 (GRCm39) |
S316N |
probably damaging |
Het |
| Fchsd1 |
A |
G |
18: 38,097,863 (GRCm39) |
I340T |
possibly damaging |
Het |
| Fn1 |
T |
C |
1: 71,663,338 (GRCm39) |
Y1050C |
probably damaging |
Het |
| Fsip2 |
A |
G |
2: 82,809,773 (GRCm39) |
I2031V |
probably benign |
Het |
| Gm10803 |
A |
C |
2: 93,394,517 (GRCm39) |
L96F |
probably damaging |
Het |
| Gm14569 |
T |
C |
X: 35,694,470 (GRCm39) |
D1413G |
probably benign |
Het |
| Gm15455 |
T |
C |
1: 33,876,432 (GRCm39) |
|
noncoding transcript |
Het |
| Gm1818 |
G |
C |
12: 48,602,318 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5420 |
A |
T |
10: 21,567,626 (GRCm39) |
|
noncoding transcript |
Het |
| Gm7104 |
A |
T |
12: 88,252,529 (GRCm39) |
|
noncoding transcript |
Het |
| Gp2 |
A |
G |
7: 119,048,337 (GRCm39) |
I427T |
probably damaging |
Het |
| Gpc4 |
G |
A |
X: 51,163,440 (GRCm39) |
R148C |
probably damaging |
Het |
| Gpr142 |
A |
C |
11: 114,695,214 (GRCm39) |
S60R |
probably benign |
Het |
| Helz2 |
T |
C |
2: 180,882,362 (GRCm39) |
R144G |
probably benign |
Het |
| Herc1 |
A |
T |
9: 66,377,608 (GRCm39) |
K3458M |
possibly damaging |
Het |
| Hnf4g |
G |
T |
3: 3,709,647 (GRCm39) |
A144S |
probably damaging |
Het |
| Irs2 |
A |
C |
8: 11,037,012 (GRCm39) |
*1322G |
probably null |
Het |
| Keg1 |
A |
G |
19: 12,696,521 (GRCm39) |
N288S |
probably damaging |
Het |
| Kif19a |
G |
A |
11: 114,658,053 (GRCm39) |
M37I |
probably benign |
Het |
| Klhl1 |
G |
A |
14: 96,374,142 (GRCm39) |
P635S |
probably benign |
Het |
| Klk14 |
G |
A |
7: 43,341,501 (GRCm39) |
C51Y |
probably damaging |
Het |
| Lsm11 |
T |
C |
11: 45,835,666 (GRCm39) |
D25G |
probably damaging |
Het |
| Manea |
A |
T |
4: 26,336,630 (GRCm39) |
Y215* |
probably null |
Het |
| Mdga2 |
C |
T |
12: 66,517,534 (GRCm39) |
C100Y |
possibly damaging |
Het |
| Mthfd1 |
T |
A |
12: 76,348,102 (GRCm39) |
M582K |
probably damaging |
Het |
| Mthfd1 |
T |
G |
12: 76,341,148 (GRCm39) |
V480G |
probably damaging |
Het |
| Nanos1 |
T |
C |
19: 60,745,418 (GRCm39) |
Y239H |
probably damaging |
Het |
| Nat8 |
G |
A |
6: 85,807,839 (GRCm39) |
T98I |
possibly damaging |
Het |
| Ndufs3 |
C |
A |
2: 90,729,004 (GRCm39) |
A161S |
probably benign |
Het |
| Nexmif |
A |
T |
X: 103,130,956 (GRCm39) |
N320K |
probably damaging |
Het |
| Or10h1 |
T |
C |
17: 33,418,751 (GRCm39) |
F239S |
probably damaging |
Het |
| Or2m12 |
A |
T |
16: 19,104,809 (GRCm39) |
V228D |
probably damaging |
Het |
| Or2r3 |
A |
T |
6: 42,448,221 (GRCm39) |
V297E |
possibly damaging |
Het |
| Or4c111 |
A |
G |
2: 88,844,387 (GRCm39) |
V7A |
probably damaging |
Het |
| Or4c122 |
C |
T |
2: 89,079,761 (GRCm39) |
M92I |
probably benign |
Het |
| Or4k15 |
T |
C |
14: 50,364,469 (GRCm39) |
V145A |
possibly damaging |
Het |
| Or52e2 |
G |
A |
7: 102,804,942 (GRCm39) |
P4L |
probably benign |
Het |
| Or6c69c |
T |
C |
10: 129,910,462 (GRCm39) |
L61P |
probably damaging |
Het |
| Pcdhb14 |
T |
A |
18: 37,583,223 (GRCm39) |
N776K |
probably benign |
Het |
| Pip5k1c |
G |
A |
10: 81,146,723 (GRCm39) |
|
probably null |
Het |
| Plk4 |
G |
A |
3: 40,756,512 (GRCm39) |
|
probably null |
Het |
| Prmt8 |
A |
G |
6: 127,688,126 (GRCm39) |
Y231H |
possibly damaging |
Het |
| Prpf4b |
T |
C |
13: 35,067,582 (GRCm39) |
|
probably benign |
Het |
| Ptpn21 |
G |
A |
12: 98,645,666 (GRCm39) |
R1091C |
probably damaging |
Het |
| Pwwp2b |
C |
T |
7: 138,835,494 (GRCm39) |
P312S |
possibly damaging |
Het |
| Rad21 |
A |
T |
15: 51,830,102 (GRCm39) |
I503K |
probably benign |
Het |
| Rai14 |
A |
G |
15: 10,574,592 (GRCm39) |
S789P |
probably damaging |
Het |
| Rbm26 |
C |
T |
14: 105,381,688 (GRCm39) |
D486N |
probably damaging |
Het |
| Rnf20 |
A |
G |
4: 49,642,016 (GRCm39) |
|
probably benign |
Het |
| Ros1 |
A |
G |
10: 52,000,171 (GRCm39) |
V1118A |
possibly damaging |
Het |
| Sema3d |
A |
C |
5: 12,634,923 (GRCm39) |
Y663S |
probably damaging |
Het |
| Serpina6 |
A |
G |
12: 103,617,971 (GRCm39) |
W281R |
probably damaging |
Het |
| Slc8a3 |
A |
G |
12: 81,246,332 (GRCm39) |
V900A |
probably damaging |
Het |
| Spats2l |
G |
T |
1: 57,918,715 (GRCm39) |
V30L |
probably damaging |
Het |
| Spg21 |
A |
G |
9: 65,383,231 (GRCm39) |
D139G |
probably damaging |
Het |
| Sun3 |
T |
C |
11: 8,988,314 (GRCm39) |
T3A |
probably damaging |
Het |
| Tep1 |
A |
G |
14: 51,066,456 (GRCm39) |
Y2335H |
probably benign |
Het |
| Tesl1 |
G |
A |
X: 23,773,480 (GRCm39) |
G327E |
probably damaging |
Het |
| Timd5 |
T |
A |
11: 46,419,359 (GRCm39) |
D58E |
probably damaging |
Het |
| Timm21 |
C |
A |
18: 84,967,539 (GRCm39) |
V112L |
possibly damaging |
Het |
| Tlk1 |
A |
T |
2: 70,572,409 (GRCm39) |
N386K |
probably benign |
Het |
| Trappc10 |
G |
T |
10: 78,052,994 (GRCm39) |
F260L |
possibly damaging |
Het |
| Trgv1 |
T |
A |
13: 19,524,401 (GRCm39) |
S42T |
probably benign |
Het |
| Trmt112 |
T |
C |
19: 6,888,121 (GRCm39) |
V91A |
probably benign |
Het |
| Ucp2 |
A |
T |
7: 100,147,579 (GRCm39) |
N186I |
possibly damaging |
Het |
| Vmn1r119 |
A |
G |
7: 20,746,245 (GRCm39) |
S46P |
probably benign |
Het |
| Vmn2r101 |
A |
T |
17: 19,831,649 (GRCm39) |
|
probably null |
Het |
| Vmn2r105 |
T |
A |
17: 20,428,676 (GRCm39) |
H800L |
probably damaging |
Het |
| Vmn2r69 |
T |
C |
7: 85,060,367 (GRCm39) |
M406V |
possibly damaging |
Het |
| Vmn2r84 |
A |
G |
10: 130,222,417 (GRCm39) |
L601P |
probably damaging |
Het |
| Vps16 |
A |
G |
2: 130,281,372 (GRCm39) |
S235G |
probably benign |
Het |
| Wap |
T |
C |
11: 6,587,339 (GRCm39) |
|
probably benign |
Het |
| Wdr11 |
A |
G |
7: 129,226,435 (GRCm39) |
I744M |
probably benign |
Het |
| Xiap |
T |
C |
X: 41,183,342 (GRCm39) |
F23L |
probably benign |
Het |
| Xkr7 |
A |
G |
2: 152,896,300 (GRCm39) |
T385A |
probably benign |
Het |
| Zfp524 |
A |
T |
7: 5,021,416 (GRCm39) |
I315F |
probably benign |
Het |
| Zfp62 |
T |
A |
11: 49,106,556 (GRCm39) |
S216T |
probably damaging |
Het |
| Znfx1 |
T |
C |
2: 166,881,746 (GRCm39) |
Y217C |
probably damaging |
Het |
|
| Other mutations in Myh7b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00931:Myh7b
|
APN |
2 |
155,472,212 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01604:Myh7b
|
APN |
2 |
155,474,327 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02179:Myh7b
|
APN |
2 |
155,456,411 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02729:Myh7b
|
APN |
2 |
155,467,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02804:Myh7b
|
APN |
2 |
155,467,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02851:Myh7b
|
APN |
2 |
155,470,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02956:Myh7b
|
APN |
2 |
155,467,874 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02956:Myh7b
|
APN |
2 |
155,474,823 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02992:Myh7b
|
APN |
2 |
155,463,330 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03060:Myh7b
|
APN |
2 |
155,474,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03061:Myh7b
|
APN |
2 |
155,462,031 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03226:Myh7b
|
APN |
2 |
155,462,403 (GRCm39) |
nonsense |
probably null |
|
|
IGL03246:Myh7b
|
APN |
2 |
155,459,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03382:Myh7b
|
APN |
2 |
155,465,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
euclidian
|
UTSW |
2 |
155,475,319 (GRCm39) |
missense |
probably benign |
0.32 |
|
imaginary
|
UTSW |
2 |
155,474,175 (GRCm39) |
missense |
probably benign |
0.36 |
|
Irrational
|
UTSW |
2 |
155,472,592 (GRCm39) |
unclassified |
probably benign |
|
|
Muscoli
|
UTSW |
2 |
155,462,038 (GRCm39) |
nonsense |
probably null |
|
|
R0015:Myh7b
|
UTSW |
2 |
155,464,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0015:Myh7b
|
UTSW |
2 |
155,464,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0109:Myh7b
|
UTSW |
2 |
155,453,594 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0309:Myh7b
|
UTSW |
2 |
155,472,592 (GRCm39) |
unclassified |
probably benign |
|
|
R0567:Myh7b
|
UTSW |
2 |
155,468,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0619:Myh7b
|
UTSW |
2 |
155,453,642 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0927:Myh7b
|
UTSW |
2 |
155,462,040 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Myh7b
|
UTSW |
2 |
155,462,347 (GRCm39) |
missense |
probably benign |
|
|
R0973:Myh7b
|
UTSW |
2 |
155,462,347 (GRCm39) |
missense |
probably benign |
|
|
R0974:Myh7b
|
UTSW |
2 |
155,462,347 (GRCm39) |
missense |
probably benign |
|
|
R1137:Myh7b
|
UTSW |
2 |
155,464,634 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1261:Myh7b
|
UTSW |
2 |
155,463,003 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1268:Myh7b
|
UTSW |
2 |
155,455,966 (GRCm39) |
nonsense |
probably null |
|
|
R1537:Myh7b
|
UTSW |
2 |
155,473,707 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1632:Myh7b
|
UTSW |
2 |
155,462,445 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1694:Myh7b
|
UTSW |
2 |
155,455,113 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1697:Myh7b
|
UTSW |
2 |
155,462,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1730:Myh7b
|
UTSW |
2 |
155,467,592 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1762:Myh7b
|
UTSW |
2 |
155,472,778 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1783:Myh7b
|
UTSW |
2 |
155,467,592 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2105:Myh7b
|
UTSW |
2 |
155,471,377 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2140:Myh7b
|
UTSW |
2 |
155,462,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2971:Myh7b
|
UTSW |
2 |
155,474,175 (GRCm39) |
missense |
probably benign |
0.36 |
|
R3838:Myh7b
|
UTSW |
2 |
155,474,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4074:Myh7b
|
UTSW |
2 |
155,460,678 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4191:Myh7b
|
UTSW |
2 |
155,475,319 (GRCm39) |
missense |
probably benign |
0.32 |
|
R4689:Myh7b
|
UTSW |
2 |
155,472,434 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4695:Myh7b
|
UTSW |
2 |
155,456,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4697:Myh7b
|
UTSW |
2 |
155,471,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4771:Myh7b
|
UTSW |
2 |
155,468,314 (GRCm39) |
nonsense |
probably null |
|
|
R4794:Myh7b
|
UTSW |
2 |
155,465,186 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4842:Myh7b
|
UTSW |
2 |
155,475,909 (GRCm39) |
missense |
probably benign |
0.45 |
|
R4871:Myh7b
|
UTSW |
2 |
155,455,420 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5023:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5025:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5050:Myh7b
|
UTSW |
2 |
155,473,670 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5055:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5056:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5161:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5284:Myh7b
|
UTSW |
2 |
155,474,234 (GRCm39) |
missense |
probably benign |
|
|
R5422:Myh7b
|
UTSW |
2 |
155,472,954 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5505:Myh7b
|
UTSW |
2 |
155,474,592 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5946:Myh7b
|
UTSW |
2 |
155,463,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6089:Myh7b
|
UTSW |
2 |
155,464,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6103:Myh7b
|
UTSW |
2 |
155,460,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6233:Myh7b
|
UTSW |
2 |
155,473,719 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6292:Myh7b
|
UTSW |
2 |
155,474,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6350:Myh7b
|
UTSW |
2 |
155,470,680 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6484:Myh7b
|
UTSW |
2 |
155,470,563 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6760:Myh7b
|
UTSW |
2 |
155,462,038 (GRCm39) |
nonsense |
probably null |
|
|
R6896:Myh7b
|
UTSW |
2 |
155,464,488 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6945:Myh7b
|
UTSW |
2 |
155,464,152 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7020:Myh7b
|
UTSW |
2 |
155,473,671 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R7052:Myh7b
|
UTSW |
2 |
155,456,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7102:Myh7b
|
UTSW |
2 |
155,464,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7248:Myh7b
|
UTSW |
2 |
155,464,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7303:Myh7b
|
UTSW |
2 |
155,460,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7360:Myh7b
|
UTSW |
2 |
155,474,460 (GRCm39) |
missense |
probably benign |
0.38 |
|
R7652:Myh7b
|
UTSW |
2 |
155,474,156 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7678:Myh7b
|
UTSW |
2 |
155,459,698 (GRCm39) |
splice site |
probably null |
|
|
R7703:Myh7b
|
UTSW |
2 |
155,462,356 (GRCm39) |
missense |
probably null |
1.00 |
|
R7711:Myh7b
|
UTSW |
2 |
155,462,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7923:Myh7b
|
UTSW |
2 |
155,467,886 (GRCm39) |
missense |
probably benign |
|
|
R7967:Myh7b
|
UTSW |
2 |
155,456,119 (GRCm39) |
splice site |
probably null |
|
|
R8045:Myh7b
|
UTSW |
2 |
155,455,101 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8176:Myh7b
|
UTSW |
2 |
155,467,886 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8272:Myh7b
|
UTSW |
2 |
155,474,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8560:Myh7b
|
UTSW |
2 |
155,465,124 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8706:Myh7b
|
UTSW |
2 |
155,453,669 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8824:Myh7b
|
UTSW |
2 |
155,472,301 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8832:Myh7b
|
UTSW |
2 |
155,475,182 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9079:Myh7b
|
UTSW |
2 |
155,465,174 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9151:Myh7b
|
UTSW |
2 |
155,474,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9311:Myh7b
|
UTSW |
2 |
155,463,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Myh7b
|
UTSW |
2 |
155,470,722 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9357:Myh7b
|
UTSW |
2 |
155,463,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9388:Myh7b
|
UTSW |
2 |
155,472,983 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9583:Myh7b
|
UTSW |
2 |
155,459,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Myh7b
|
UTSW |
2 |
155,455,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9738:Myh7b
|
UTSW |
2 |
155,455,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0013:Myh7b
|
UTSW |
2 |
155,473,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGACCTACTCCATTCCTGTGGG -3'
(R):5'- AATGCAGTAGGTTGAGGCGC -3'
Sequencing Primer
(F):5'- CTCCCTGGATGCAGAGACAAG -3'
(R):5'- TTGAGGCGCTCGGTGGC -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation