Incidental Mutation 'R7102:Myh7b'
| ID |
550885 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh7b
|
| Ensembl Gene |
ENSMUSG00000074652 |
| Gene Name |
myosin, heavy chain 7B, cardiac muscle, beta |
| Synonyms |
Myh14 |
| MMRRC Submission |
045194-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R7102 (G1)
|
| Quality Score |
225.009 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
155453132-155476227 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 155464119 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 540
(E540G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000090672
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000092995]
|
| AlphaFold |
A2AQP0 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000092995
AA Change: E540G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000090672
Gene: ENSMUSG00000074652
AA Change: E540G
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
32 |
72 |
4.7e-14 |
PFAM |
|
MYSc
|
78 |
786 |
N/A |
SMART |
|
IQ
|
787 |
809 |
2.6e0 |
SMART |
|
Pfam:Myosin_tail_1
|
850 |
1931 |
5.5e-149 |
PFAM |
|
| Coding Region Coverage |
- 1x: 100.0%
- 3x: 100.0%
- 10x: 99.7%
- 20x: 99.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a myosin heavy chain. The encoded protein forms a hexamer comprised of two heavy chains, two alkali light chains, and two regulatory light chain components. This complex functions in muscle contraction. [provided by RefSeq, Jun 2013]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 98 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca13 |
A |
T |
11: 9,285,215 (GRCm39) |
H3283L |
probably damaging |
Het |
| Abcb1a |
T |
G |
5: 8,744,072 (GRCm39) |
S233A |
probably benign |
Het |
| Actr10 |
T |
C |
12: 70,999,805 (GRCm39) |
|
probably null |
Het |
| Acvr2b |
C |
T |
9: 119,261,619 (GRCm39) |
A380V |
probably damaging |
Het |
| Adcy5 |
A |
G |
16: 35,119,995 (GRCm39) |
E1168G |
probably damaging |
Het |
| Akap12 |
C |
T |
10: 4,303,226 (GRCm39) |
T117I |
probably damaging |
Het |
| Alox5 |
T |
A |
6: 116,390,429 (GRCm39) |
Y516F |
probably benign |
Het |
| Amigo2 |
T |
C |
15: 97,143,741 (GRCm39) |
N227S |
probably damaging |
Het |
| Anpep |
C |
A |
7: 79,486,061 (GRCm39) |
V554L |
probably benign |
Het |
| Ap5b1 |
T |
A |
19: 5,620,215 (GRCm39) |
V545E |
possibly damaging |
Het |
| Bbs9 |
C |
T |
9: 22,490,849 (GRCm39) |
L326F |
probably damaging |
Het |
| Bltp1 |
T |
G |
3: 36,994,947 (GRCm39) |
Y990D |
probably damaging |
Het |
| Cadps |
C |
T |
14: 12,603,738 (GRCm38) |
G361R |
probably damaging |
Het |
| Ccdc57 |
C |
A |
11: 120,812,557 (GRCm39) |
E66* |
probably null |
Het |
| Ccr6 |
G |
A |
17: 8,475,019 (GRCm39) |
V75I |
probably benign |
Het |
| Cdk6 |
T |
C |
5: 3,570,709 (GRCm39) |
F300S |
probably damaging |
Het |
| Cenpb |
A |
C |
2: 131,020,799 (GRCm39) |
V333G |
probably damaging |
Het |
| Clca4a |
T |
C |
3: 144,667,670 (GRCm39) |
I434V |
probably benign |
Het |
| Coro2b |
T |
A |
9: 62,328,667 (GRCm39) |
D447V |
possibly damaging |
Het |
| Cpeb3 |
T |
C |
19: 37,152,119 (GRCm39) |
S86G |
probably benign |
Het |
| Cry2 |
C |
A |
2: 92,243,438 (GRCm39) |
A468S |
probably damaging |
Het |
| Csf2rb2 |
T |
C |
15: 78,181,272 (GRCm39) |
Y40C |
probably damaging |
Het |
| Ddx49 |
T |
A |
8: 70,753,726 (GRCm39) |
T48S |
probably damaging |
Het |
| Dennd10 |
T |
A |
19: 60,821,034 (GRCm39) |
M272K |
probably damaging |
Het |
| Dip2c |
A |
G |
13: 9,654,572 (GRCm39) |
T727A |
probably benign |
Het |
| Dnai3 |
A |
T |
3: 145,761,459 (GRCm39) |
S632R |
possibly damaging |
Het |
| Ebf4 |
A |
T |
2: 130,151,651 (GRCm39) |
I183F |
probably benign |
Het |
| Elavl3 |
G |
T |
9: 21,930,025 (GRCm39) |
P293Q |
possibly damaging |
Het |
| Esyt1 |
A |
T |
10: 128,352,105 (GRCm39) |
L768Q |
probably damaging |
Het |
| Fat2 |
G |
A |
11: 55,174,260 (GRCm39) |
P2151L |
probably damaging |
Het |
| Fgfbp3 |
G |
T |
19: 36,896,606 (GRCm39) |
A4E |
possibly damaging |
Het |
| Flg |
T |
A |
3: 93,200,335 (GRCm39) |
V277D |
unknown |
Het |
| Fndc3b |
T |
C |
3: 27,524,383 (GRCm39) |
D459G |
possibly damaging |
Het |
| Fras1 |
A |
G |
5: 96,718,900 (GRCm39) |
Q438R |
probably benign |
Het |
| Glipr1l2 |
A |
T |
10: 111,928,330 (GRCm39) |
|
probably null |
Het |
| Gm7347 |
T |
A |
5: 26,262,382 (GRCm39) |
|
probably null |
Het |
| Grm6 |
G |
A |
11: 50,753,804 (GRCm39) |
V703I |
possibly damaging |
Het |
| Gtf2h1 |
T |
A |
7: 46,468,550 (GRCm39) |
V496E |
probably benign |
Het |
| Ifna12 |
A |
G |
4: 88,521,388 (GRCm39) |
L53P |
probably damaging |
Het |
| Invs |
T |
A |
4: 48,407,674 (GRCm39) |
S550T |
probably benign |
Het |
| Irak2 |
G |
T |
6: 113,663,810 (GRCm39) |
C453F |
probably damaging |
Het |
| Itih2 |
G |
T |
2: 10,110,574 (GRCm39) |
Q506K |
probably benign |
Het |
| Kidins220 |
T |
C |
12: 25,107,662 (GRCm39) |
I1614T |
probably benign |
Het |
| Krtap5-3 |
T |
A |
7: 141,755,992 (GRCm39) |
C276* |
probably null |
Het |
| Lama3 |
T |
A |
18: 12,685,870 (GRCm39) |
M1128K |
possibly damaging |
Het |
| Lhfpl4 |
C |
T |
6: 113,171,106 (GRCm39) |
A27T |
possibly damaging |
Het |
| Lyplal1 |
A |
G |
1: 185,832,524 (GRCm39) |
V77A |
probably damaging |
Het |
| Malrd1 |
A |
T |
2: 16,147,114 (GRCm39) |
E1985D |
unknown |
Het |
| Mlx |
A |
C |
11: 100,979,802 (GRCm39) |
Q161P |
probably benign |
Het |
| Mroh2b |
T |
A |
15: 4,977,485 (GRCm39) |
M1279K |
probably benign |
Het |
| Neb |
T |
A |
2: 52,194,067 (GRCm39) |
D653V |
probably damaging |
Het |
| Nek10 |
T |
A |
14: 14,828,517 (GRCm38) |
L113Q |
probably damaging |
Het |
| Nlrp4c |
T |
A |
7: 6,068,708 (GRCm39) |
L203* |
probably null |
Het |
| Nscme3l |
T |
A |
19: 5,553,623 (GRCm39) |
T53S |
probably benign |
Het |
| Ntpcr |
T |
A |
8: 126,456,794 (GRCm39) |
C5S |
unknown |
Het |
| Nwd1 |
A |
G |
8: 73,421,957 (GRCm39) |
D1001G |
probably damaging |
Het |
| Or12j5 |
T |
A |
7: 140,084,229 (GRCm39) |
T48S |
probably benign |
Het |
| Or14a256 |
C |
T |
7: 86,265,475 (GRCm39) |
C126Y |
probably benign |
Het |
| Or4p22 |
T |
A |
2: 88,317,492 (GRCm39) |
C139S |
probably damaging |
Het |
| Or6c208 |
A |
C |
10: 129,224,036 (GRCm39) |
D178A |
probably damaging |
Het |
| Osbpl3 |
T |
A |
6: 50,297,115 (GRCm39) |
S564C |
probably damaging |
Het |
| Pax6 |
C |
A |
2: 105,522,604 (GRCm39) |
P264T |
probably damaging |
Het |
| Plppr4 |
T |
C |
3: 117,116,832 (GRCm39) |
R342G |
probably damaging |
Het |
| Prg4 |
C |
T |
1: 150,328,005 (GRCm39) |
C220Y |
probably damaging |
Het |
| Prune2 |
T |
A |
19: 17,098,577 (GRCm39) |
D1360E |
probably benign |
Het |
| Ranbp2 |
T |
A |
10: 58,299,772 (GRCm39) |
S469T |
probably damaging |
Het |
| Rbfox1 |
A |
T |
16: 7,187,698 (GRCm39) |
K43N |
probably benign |
Het |
| Rgs22 |
T |
C |
15: 36,122,459 (GRCm39) |
D25G |
probably damaging |
Het |
| Rnf113a2 |
G |
A |
12: 84,464,545 (GRCm39) |
G146S |
probably damaging |
Het |
| Sbpl |
T |
A |
17: 24,173,608 (GRCm39) |
K55* |
probably null |
Het |
| Scel |
G |
A |
14: 103,781,268 (GRCm39) |
W138* |
probably null |
Het |
| Scgb2b19 |
T |
C |
7: 32,979,711 (GRCm39) |
I12V |
probably null |
Het |
| Scn9a |
T |
A |
2: 66,379,359 (GRCm39) |
M358L |
probably damaging |
Het |
| Sdk2 |
C |
A |
11: 113,733,516 (GRCm39) |
E924* |
probably null |
Het |
| Sipa1l3 |
T |
C |
7: 29,048,012 (GRCm39) |
Q1292R |
possibly damaging |
Het |
| Skint4 |
G |
A |
4: 111,975,298 (GRCm39) |
G86D |
probably damaging |
Het |
| Slc28a3 |
C |
T |
13: 58,736,028 (GRCm39) |
V57I |
probably benign |
Het |
| Slc9a4 |
T |
C |
1: 40,662,559 (GRCm39) |
S609P |
probably damaging |
Het |
| Slc9a4 |
C |
T |
1: 40,619,799 (GRCm39) |
P42S |
probably benign |
Het |
| Slitrk1 |
T |
A |
14: 109,150,061 (GRCm39) |
T217S |
probably benign |
Het |
| Spindoc |
C |
T |
19: 7,335,807 (GRCm39) |
R327H |
probably benign |
Het |
| Stk36 |
T |
C |
1: 74,661,382 (GRCm39) |
S470P |
probably benign |
Het |
| Sypl1 |
C |
T |
12: 33,024,254 (GRCm39) |
P196L |
probably benign |
Het |
| Tekt4 |
T |
A |
17: 25,693,718 (GRCm39) |
I285N |
probably damaging |
Het |
| Tgm5 |
T |
A |
2: 120,876,979 (GRCm39) |
I686F |
possibly damaging |
Het |
| Thsd4 |
C |
A |
9: 59,883,587 (GRCm39) |
R933L |
probably damaging |
Het |
| Treml1 |
T |
A |
17: 48,673,700 (GRCm39) |
I237N |
probably damaging |
Het |
| Txndc16 |
T |
C |
14: 45,442,839 (GRCm39) |
I119V |
probably benign |
Het |
| Ubr3 |
C |
A |
2: 69,728,166 (GRCm39) |
N176K |
probably damaging |
Het |
| Vit |
A |
G |
17: 78,932,426 (GRCm39) |
Y511C |
probably damaging |
Het |
| Vwa5b2 |
G |
A |
16: 20,422,984 (GRCm39) |
G994D |
probably benign |
Het |
| Wnk1 |
T |
C |
6: 119,925,268 (GRCm39) |
T1648A |
unknown |
Het |
| Ythdf1 |
G |
A |
2: 180,553,315 (GRCm39) |
T300I |
probably damaging |
Het |
| Zan |
A |
G |
5: 137,452,462 (GRCm39) |
|
probably null |
Het |
| Zbbx |
A |
G |
3: 75,019,401 (GRCm39) |
L103P |
probably benign |
Het |
| Zfp105 |
A |
G |
9: 122,758,869 (GRCm39) |
D180G |
probably damaging |
Het |
| Zfp114 |
T |
A |
7: 23,880,083 (GRCm39) |
L144Q |
possibly damaging |
Het |
| Zfp128 |
T |
C |
7: 12,624,399 (GRCm39) |
C256R |
probably damaging |
Het |
|
| Other mutations in Myh7b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00931:Myh7b
|
APN |
2 |
155,472,212 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01604:Myh7b
|
APN |
2 |
155,474,327 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02179:Myh7b
|
APN |
2 |
155,456,411 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02729:Myh7b
|
APN |
2 |
155,467,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02804:Myh7b
|
APN |
2 |
155,467,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02851:Myh7b
|
APN |
2 |
155,470,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02956:Myh7b
|
APN |
2 |
155,467,874 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02956:Myh7b
|
APN |
2 |
155,474,823 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02992:Myh7b
|
APN |
2 |
155,463,330 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03060:Myh7b
|
APN |
2 |
155,474,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03061:Myh7b
|
APN |
2 |
155,462,031 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03226:Myh7b
|
APN |
2 |
155,462,403 (GRCm39) |
nonsense |
probably null |
|
|
IGL03246:Myh7b
|
APN |
2 |
155,459,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03382:Myh7b
|
APN |
2 |
155,465,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
euclidian
|
UTSW |
2 |
155,475,319 (GRCm39) |
missense |
probably benign |
0.32 |
|
imaginary
|
UTSW |
2 |
155,474,175 (GRCm39) |
missense |
probably benign |
0.36 |
|
Irrational
|
UTSW |
2 |
155,472,592 (GRCm39) |
unclassified |
probably benign |
|
|
Muscoli
|
UTSW |
2 |
155,462,038 (GRCm39) |
nonsense |
probably null |
|
|
R0015:Myh7b
|
UTSW |
2 |
155,464,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0015:Myh7b
|
UTSW |
2 |
155,464,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0109:Myh7b
|
UTSW |
2 |
155,453,594 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0309:Myh7b
|
UTSW |
2 |
155,472,592 (GRCm39) |
unclassified |
probably benign |
|
|
R0567:Myh7b
|
UTSW |
2 |
155,468,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0619:Myh7b
|
UTSW |
2 |
155,453,642 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0927:Myh7b
|
UTSW |
2 |
155,462,040 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Myh7b
|
UTSW |
2 |
155,462,347 (GRCm39) |
missense |
probably benign |
|
|
R0973:Myh7b
|
UTSW |
2 |
155,462,347 (GRCm39) |
missense |
probably benign |
|
|
R0974:Myh7b
|
UTSW |
2 |
155,462,347 (GRCm39) |
missense |
probably benign |
|
|
R1137:Myh7b
|
UTSW |
2 |
155,464,634 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1261:Myh7b
|
UTSW |
2 |
155,463,003 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1268:Myh7b
|
UTSW |
2 |
155,455,966 (GRCm39) |
nonsense |
probably null |
|
|
R1537:Myh7b
|
UTSW |
2 |
155,473,707 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1632:Myh7b
|
UTSW |
2 |
155,462,445 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1694:Myh7b
|
UTSW |
2 |
155,455,113 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1697:Myh7b
|
UTSW |
2 |
155,462,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1730:Myh7b
|
UTSW |
2 |
155,467,592 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1762:Myh7b
|
UTSW |
2 |
155,472,778 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1783:Myh7b
|
UTSW |
2 |
155,467,592 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2105:Myh7b
|
UTSW |
2 |
155,471,377 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2140:Myh7b
|
UTSW |
2 |
155,462,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2971:Myh7b
|
UTSW |
2 |
155,474,175 (GRCm39) |
missense |
probably benign |
0.36 |
|
R3838:Myh7b
|
UTSW |
2 |
155,474,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4074:Myh7b
|
UTSW |
2 |
155,460,678 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4191:Myh7b
|
UTSW |
2 |
155,475,319 (GRCm39) |
missense |
probably benign |
0.32 |
|
R4689:Myh7b
|
UTSW |
2 |
155,472,434 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4695:Myh7b
|
UTSW |
2 |
155,456,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4697:Myh7b
|
UTSW |
2 |
155,471,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4771:Myh7b
|
UTSW |
2 |
155,468,314 (GRCm39) |
nonsense |
probably null |
|
|
R4794:Myh7b
|
UTSW |
2 |
155,465,186 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4842:Myh7b
|
UTSW |
2 |
155,475,909 (GRCm39) |
missense |
probably benign |
0.45 |
|
R4871:Myh7b
|
UTSW |
2 |
155,455,420 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5022:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5023:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5025:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5050:Myh7b
|
UTSW |
2 |
155,473,670 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5055:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5056:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5161:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5284:Myh7b
|
UTSW |
2 |
155,474,234 (GRCm39) |
missense |
probably benign |
|
|
R5422:Myh7b
|
UTSW |
2 |
155,472,954 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5505:Myh7b
|
UTSW |
2 |
155,474,592 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5946:Myh7b
|
UTSW |
2 |
155,463,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6089:Myh7b
|
UTSW |
2 |
155,464,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6103:Myh7b
|
UTSW |
2 |
155,460,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6233:Myh7b
|
UTSW |
2 |
155,473,719 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6292:Myh7b
|
UTSW |
2 |
155,474,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6350:Myh7b
|
UTSW |
2 |
155,470,680 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6484:Myh7b
|
UTSW |
2 |
155,470,563 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6760:Myh7b
|
UTSW |
2 |
155,462,038 (GRCm39) |
nonsense |
probably null |
|
|
R6896:Myh7b
|
UTSW |
2 |
155,464,488 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6945:Myh7b
|
UTSW |
2 |
155,464,152 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7020:Myh7b
|
UTSW |
2 |
155,473,671 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R7052:Myh7b
|
UTSW |
2 |
155,456,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7248:Myh7b
|
UTSW |
2 |
155,464,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7303:Myh7b
|
UTSW |
2 |
155,460,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7360:Myh7b
|
UTSW |
2 |
155,474,460 (GRCm39) |
missense |
probably benign |
0.38 |
|
R7652:Myh7b
|
UTSW |
2 |
155,474,156 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7678:Myh7b
|
UTSW |
2 |
155,459,698 (GRCm39) |
splice site |
probably null |
|
|
R7703:Myh7b
|
UTSW |
2 |
155,462,356 (GRCm39) |
missense |
probably null |
1.00 |
|
R7711:Myh7b
|
UTSW |
2 |
155,462,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7923:Myh7b
|
UTSW |
2 |
155,467,886 (GRCm39) |
missense |
probably benign |
|
|
R7967:Myh7b
|
UTSW |
2 |
155,456,119 (GRCm39) |
splice site |
probably null |
|
|
R8045:Myh7b
|
UTSW |
2 |
155,455,101 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8176:Myh7b
|
UTSW |
2 |
155,467,886 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8272:Myh7b
|
UTSW |
2 |
155,474,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8560:Myh7b
|
UTSW |
2 |
155,465,124 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8706:Myh7b
|
UTSW |
2 |
155,453,669 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8824:Myh7b
|
UTSW |
2 |
155,472,301 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8832:Myh7b
|
UTSW |
2 |
155,475,182 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9079:Myh7b
|
UTSW |
2 |
155,465,174 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9151:Myh7b
|
UTSW |
2 |
155,474,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9311:Myh7b
|
UTSW |
2 |
155,463,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Myh7b
|
UTSW |
2 |
155,470,722 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9357:Myh7b
|
UTSW |
2 |
155,463,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9388:Myh7b
|
UTSW |
2 |
155,472,983 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9583:Myh7b
|
UTSW |
2 |
155,459,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Myh7b
|
UTSW |
2 |
155,455,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9738:Myh7b
|
UTSW |
2 |
155,455,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0013:Myh7b
|
UTSW |
2 |
155,473,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACACACGTGCCTGACTTCTC -3'
(R):5'- AAAATATTGACCCAGGTGGCG -3'
Sequencing Primer
(F):5'- GACTTCTCCTGTACACGGCTGG -3'
(R):5'- ACAGTGGTTGAGTACAGGGCTC -3'
|
| Posted On |
2019-05-15 |
Incidental Mutation