Incidental Mutation 'R0453:Rictor'
| ID |
39809 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Rictor
|
| Ensembl Gene |
ENSMUSG00000050310 |
| Gene Name |
RPTOR independent companion of MTOR, complex 2 |
| Synonyms |
D530039E11Rik, 4921505C17Rik, 6030405M08Rik |
| MMRRC Submission |
038653-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0453 (G1)
|
| Quality Score |
90 |
|
Status
|
Not validated
|
| Chromosome |
15 |
| Chromosomal Location |
6737860-6829882 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 6738123 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 20
(D20G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000051809
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000061656]
|
| AlphaFold |
Q6QI06 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000061656
AA Change: D20G
PolyPhen 2
Score 0.010 (Sensitivity: 0.96; Specificity: 0.77)
|
| SMART Domains |
Protein: ENSMUSP00000051809
Gene: ENSMUSG00000050310
AA Change: D20G
| Domain | Start | End | E-Value | Type |
|---|
|
RICTOR_N
|
57 |
439 |
4.02e-185 |
SMART |
|
RICTOR_M
|
523 |
742 |
5.66e-98 |
SMART |
|
RasGEF_N_2
|
743 |
857 |
1.26e-54 |
SMART |
|
RICTOR_V
|
920 |
992 |
1.44e-40 |
SMART |
|
low complexity region
|
1019 |
1043 |
N/A |
INTRINSIC |
|
RICTOR_phospho
|
1084 |
1189 |
4.06e-58 |
SMART |
|
low complexity region
|
1221 |
1239 |
N/A |
INTRINSIC |
|
low complexity region
|
1255 |
1266 |
N/A |
INTRINSIC |
|
low complexity region
|
1273 |
1287 |
N/A |
INTRINSIC |
|
low complexity region
|
1404 |
1414 |
N/A |
INTRINSIC |
|
low complexity region
|
1464 |
1474 |
N/A |
INTRINSIC |
|
low complexity region
|
1616 |
1628 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000226181
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000226201
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000228266
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000228918
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.4%
- 20x: 93.6%
|
| Validation Efficiency |
99% (97/98) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] RICTOR and MTOR (FRAP1; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004 [PubMed 15268862]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality during organogenesis associated with abnormal placental morphology. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acad10 |
T |
A |
5: 121,765,445 (GRCm39) |
K843* |
probably null |
Het |
| Adam26b |
T |
C |
8: 43,973,387 (GRCm39) |
I538M |
probably benign |
Het |
| Adamtsl1 |
T |
C |
4: 86,150,852 (GRCm39) |
Y337H |
probably damaging |
Het |
| Ak7 |
T |
C |
12: 105,682,307 (GRCm39) |
M156T |
probably damaging |
Het |
| Aldh3a1 |
A |
G |
11: 61,106,338 (GRCm39) |
M238V |
probably benign |
Het |
| Asic4 |
T |
A |
1: 75,450,155 (GRCm39) |
|
probably benign |
Het |
| AW551984 |
A |
G |
9: 39,511,937 (GRCm39) |
S25P |
probably damaging |
Het |
| Bbs7 |
T |
A |
3: 36,661,818 (GRCm39) |
Y127F |
possibly damaging |
Het |
| Bco1 |
G |
A |
8: 117,835,516 (GRCm39) |
E156K |
possibly damaging |
Het |
| Becn1 |
T |
C |
11: 101,181,275 (GRCm39) |
D342G |
probably damaging |
Het |
| Birc6 |
T |
A |
17: 74,956,749 (GRCm39) |
I3575N |
probably damaging |
Het |
| Brd10 |
T |
C |
19: 29,731,068 (GRCm39) |
Y715C |
probably damaging |
Het |
| Cc2d2a |
A |
T |
5: 43,860,636 (GRCm39) |
M522L |
probably benign |
Het |
| Cerkl |
A |
G |
2: 79,172,795 (GRCm39) |
F293L |
probably benign |
Het |
| Chil3 |
T |
G |
3: 106,056,221 (GRCm39) |
N311T |
probably benign |
Het |
| Cpeb2 |
T |
A |
5: 43,443,056 (GRCm39) |
|
probably benign |
Het |
| Cpxm2 |
A |
G |
7: 131,730,134 (GRCm39) |
S162P |
probably damaging |
Het |
| Cracr2b |
A |
C |
7: 141,044,176 (GRCm39) |
E136A |
probably damaging |
Het |
| Cyp2a4 |
T |
A |
7: 26,012,258 (GRCm39) |
M347K |
probably benign |
Het |
| Dicer1 |
C |
A |
12: 104,668,889 (GRCm39) |
R1264S |
probably benign |
Het |
| Dlgap1 |
T |
A |
17: 71,068,341 (GRCm39) |
N609K |
probably benign |
Het |
| Dnhd1 |
A |
G |
7: 105,323,651 (GRCm39) |
T641A |
probably benign |
Het |
| Egfl8 |
T |
C |
17: 34,833,856 (GRCm39) |
Y74C |
probably damaging |
Het |
| Esyt1 |
A |
G |
10: 128,348,078 (GRCm39) |
S901P |
probably benign |
Het |
| Fam83e |
A |
T |
7: 45,373,372 (GRCm39) |
D246V |
probably damaging |
Het |
| Galnt2 |
T |
C |
8: 125,065,323 (GRCm39) |
|
probably benign |
Het |
| Hdc |
A |
G |
2: 126,436,871 (GRCm39) |
|
probably benign |
Het |
| Herc1 |
A |
C |
9: 66,307,054 (GRCm39) |
Q958P |
probably benign |
Het |
| Iqcg |
T |
A |
16: 32,870,213 (GRCm39) |
|
probably benign |
Het |
| Iqub |
A |
T |
6: 24,450,829 (GRCm39) |
F590Y |
probably damaging |
Het |
| Jak2 |
T |
C |
19: 29,289,238 (GRCm39) |
I1130T |
probably benign |
Het |
| Kbtbd11 |
G |
A |
8: 15,077,499 (GRCm39) |
A33T |
probably benign |
Het |
| Kcnip4 |
A |
G |
5: 48,667,054 (GRCm39) |
L37P |
probably damaging |
Het |
| Klk6 |
A |
G |
7: 43,477,963 (GRCm39) |
N112D |
probably damaging |
Het |
| Kmt2c |
G |
A |
5: 25,559,745 (GRCm39) |
T1011I |
probably damaging |
Het |
| Knl1 |
A |
T |
2: 118,898,869 (GRCm39) |
K190M |
probably damaging |
Het |
| Lama3 |
T |
A |
18: 12,598,535 (GRCm39) |
S981T |
possibly damaging |
Het |
| Lrrc18 |
T |
C |
14: 32,730,608 (GRCm39) |
L49P |
probably damaging |
Het |
| Lrrc31 |
T |
C |
3: 30,741,674 (GRCm39) |
E245G |
probably damaging |
Het |
| Lypd10 |
T |
A |
7: 24,413,712 (GRCm39) |
S243T |
probably benign |
Het |
| Macf1 |
T |
C |
4: 123,338,737 (GRCm39) |
I2456M |
probably benign |
Het |
| Mcm6 |
T |
A |
1: 128,261,292 (GRCm39) |
T771S |
probably benign |
Het |
| Met |
A |
C |
6: 17,534,197 (GRCm39) |
Y680S |
possibly damaging |
Het |
| Mixl1 |
T |
A |
1: 180,524,211 (GRCm39) |
T123S |
probably damaging |
Het |
| Myh8 |
A |
T |
11: 67,183,731 (GRCm39) |
I787F |
probably benign |
Het |
| Myocd |
A |
G |
11: 65,087,051 (GRCm39) |
F292S |
probably damaging |
Het |
| Neb |
T |
C |
2: 52,203,902 (GRCm39) |
|
probably null |
Het |
| Nfe2l1 |
A |
G |
11: 96,718,194 (GRCm39) |
S114P |
probably damaging |
Het |
| Nrxn2 |
T |
C |
19: 6,541,551 (GRCm39) |
S986P |
probably damaging |
Het |
| Oprl1 |
T |
C |
2: 181,360,527 (GRCm39) |
|
probably null |
Het |
| Or11h6 |
T |
C |
14: 50,880,461 (GRCm39) |
V241A |
possibly damaging |
Het |
| Or4a73 |
A |
T |
2: 89,421,095 (GRCm39) |
Y121* |
probably null |
Het |
| Or5b101 |
T |
G |
19: 13,005,295 (GRCm39) |
T133P |
probably damaging |
Het |
| Or6c8 |
A |
G |
10: 128,915,640 (GRCm39) |
F64S |
probably damaging |
Het |
| Or8b53 |
G |
A |
9: 38,667,425 (GRCm39) |
G147D |
probably damaging |
Het |
| Or8c9 |
A |
T |
9: 38,241,467 (GRCm39) |
T195S |
probably benign |
Het |
| Panx2 |
T |
A |
15: 88,952,610 (GRCm39) |
I359N |
probably damaging |
Het |
| Pik3c2b |
T |
A |
1: 133,005,134 (GRCm39) |
V545E |
probably damaging |
Het |
| Piwil4 |
T |
C |
9: 14,638,748 (GRCm39) |
N259S |
probably benign |
Het |
| Plcxd2 |
A |
T |
16: 45,800,919 (GRCm39) |
F102I |
probably damaging |
Het |
| Pld5 |
A |
T |
1: 175,917,522 (GRCm39) |
M75K |
possibly damaging |
Het |
| Pmp22 |
T |
A |
11: 63,041,929 (GRCm39) |
|
probably benign |
Het |
| Polr2a |
A |
G |
11: 69,631,845 (GRCm39) |
S1074P |
possibly damaging |
Het |
| Pop1 |
T |
A |
15: 34,526,352 (GRCm39) |
V649E |
possibly damaging |
Het |
| Prc1 |
A |
G |
7: 79,962,850 (GRCm39) |
N548S |
probably damaging |
Het |
| Prss51 |
T |
C |
14: 64,334,588 (GRCm39) |
L202P |
probably damaging |
Het |
| Rhpn1 |
T |
C |
15: 75,585,428 (GRCm39) |
S576P |
possibly damaging |
Het |
| Rpl13a-ps1 |
A |
T |
19: 50,018,645 (GRCm39) |
L177* |
probably null |
Het |
| Rpl23a-ps1 |
T |
G |
1: 46,021,087 (GRCm39) |
|
noncoding transcript |
Het |
| Saa2 |
A |
G |
7: 46,402,902 (GRCm39) |
D51G |
probably damaging |
Het |
| Sec31a |
A |
T |
5: 100,551,977 (GRCm39) |
|
probably benign |
Het |
| Secisbp2 |
G |
A |
13: 51,837,361 (GRCm39) |
E841K |
possibly damaging |
Het |
| Serinc1 |
A |
G |
10: 57,393,306 (GRCm39) |
Y437H |
probably damaging |
Het |
| Slc39a12 |
A |
T |
2: 14,440,492 (GRCm39) |
H481L |
probably benign |
Het |
| Suz12 |
T |
A |
11: 79,920,859 (GRCm39) |
N586K |
probably damaging |
Het |
| Synm |
T |
C |
7: 67,386,630 (GRCm39) |
Y344C |
possibly damaging |
Het |
| Tas2r104 |
A |
G |
6: 131,662,304 (GRCm39) |
V135A |
probably benign |
Het |
| Tdrd9 |
T |
C |
12: 112,034,673 (GRCm39) |
S1371P |
probably benign |
Het |
| Tg |
T |
A |
15: 66,700,382 (GRCm39) |
D893E |
probably benign |
Het |
| Thoc5 |
C |
A |
11: 4,868,217 (GRCm39) |
D423E |
possibly damaging |
Het |
| Trim11 |
G |
A |
11: 58,881,361 (GRCm39) |
R418H |
probably damaging |
Het |
| Trim52 |
T |
G |
14: 106,344,399 (GRCm39) |
V19G |
probably damaging |
Het |
| Tuba4a |
C |
A |
1: 75,192,502 (GRCm39) |
V371L |
probably damaging |
Het |
| Ugt8a |
A |
G |
3: 125,708,606 (GRCm39) |
V168A |
probably benign |
Het |
| Ulk1 |
C |
T |
5: 110,938,951 (GRCm39) |
G496R |
probably damaging |
Het |
| Usp40 |
A |
G |
1: 87,874,320 (GRCm39) |
*1236Q |
probably null |
Het |
| Vmn2r100 |
C |
A |
17: 19,742,382 (GRCm39) |
P252Q |
possibly damaging |
Het |
| Vmn2r24 |
A |
G |
6: 123,757,350 (GRCm39) |
|
probably null |
Het |
| Vmn2r53 |
A |
G |
7: 12,316,338 (GRCm39) |
Y494H |
probably damaging |
Het |
| Vmn2r65 |
T |
A |
7: 84,595,442 (GRCm39) |
D414V |
probably benign |
Het |
| Wdr26 |
A |
T |
1: 181,010,444 (GRCm39) |
L519* |
probably null |
Het |
| Wnk1 |
A |
G |
6: 119,940,112 (GRCm39) |
V173A |
probably damaging |
Het |
| Zfp217 |
C |
T |
2: 169,957,382 (GRCm39) |
A539T |
probably benign |
Het |
| Zfp318 |
T |
C |
17: 46,707,634 (GRCm39) |
S231P |
probably damaging |
Het |
| Zfp398 |
T |
C |
6: 47,842,782 (GRCm39) |
V146A |
probably benign |
Het |
| Zfp410 |
T |
C |
12: 84,378,486 (GRCm39) |
M270T |
probably damaging |
Het |
| Zfp445 |
A |
T |
9: 122,682,578 (GRCm39) |
H454Q |
possibly damaging |
Het |
|
| Other mutations in Rictor |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00488:Rictor
|
APN |
15 |
6,816,071 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00785:Rictor
|
APN |
15 |
6,806,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00801:Rictor
|
APN |
15 |
6,824,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01072:Rictor
|
APN |
15 |
6,819,043 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01139:Rictor
|
APN |
15 |
6,807,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01303:Rictor
|
APN |
15 |
6,738,119 (GRCm39) |
missense |
probably benign |
0.10 |
|
IGL01307:Rictor
|
APN |
15 |
6,804,085 (GRCm39) |
splice site |
probably null |
|
|
IGL01767:Rictor
|
APN |
15 |
6,806,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01774:Rictor
|
APN |
15 |
6,799,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01800:Rictor
|
APN |
15 |
6,804,182 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02192:Rictor
|
APN |
15 |
6,815,895 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02503:Rictor
|
APN |
15 |
6,815,924 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02652:Rictor
|
APN |
15 |
6,805,668 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02656:Rictor
|
APN |
15 |
6,806,401 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02752:Rictor
|
APN |
15 |
6,816,852 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03000:Rictor
|
APN |
15 |
6,798,721 (GRCm39) |
splice site |
probably benign |
|
|
IGL03118:Rictor
|
APN |
15 |
6,788,999 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03182:Rictor
|
APN |
15 |
6,819,079 (GRCm39) |
missense |
probably benign |
0.08 |
|
Tense
|
UTSW |
15 |
6,788,977 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
Tonus
|
UTSW |
15 |
6,798,815 (GRCm39) |
critical splice donor site |
probably null |
|
|
Torrid
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0149:Rictor
|
UTSW |
15 |
6,813,588 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R0288:Rictor
|
UTSW |
15 |
6,816,021 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0304:Rictor
|
UTSW |
15 |
6,815,852 (GRCm39) |
splice site |
probably null |
|
|
R0336:Rictor
|
UTSW |
15 |
6,806,234 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0361:Rictor
|
UTSW |
15 |
6,813,588 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R0423:Rictor
|
UTSW |
15 |
6,803,381 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0515:Rictor
|
UTSW |
15 |
6,798,782 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0630:Rictor
|
UTSW |
15 |
6,823,973 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0730:Rictor
|
UTSW |
15 |
6,803,467 (GRCm39) |
splice site |
probably benign |
|
|
R0744:Rictor
|
UTSW |
15 |
6,793,759 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0836:Rictor
|
UTSW |
15 |
6,793,759 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0881:Rictor
|
UTSW |
15 |
6,821,151 (GRCm39) |
missense |
probably benign |
|
|
R1114:Rictor
|
UTSW |
15 |
6,823,486 (GRCm39) |
nonsense |
probably null |
|
|
R1367:Rictor
|
UTSW |
15 |
6,820,119 (GRCm39) |
splice site |
probably benign |
|
|
R1655:Rictor
|
UTSW |
15 |
6,801,693 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1678:Rictor
|
UTSW |
15 |
6,785,952 (GRCm39) |
missense |
probably benign |
0.07 |
|
R1679:Rictor
|
UTSW |
15 |
6,797,571 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1754:Rictor
|
UTSW |
15 |
6,764,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1757:Rictor
|
UTSW |
15 |
6,803,343 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1762:Rictor
|
UTSW |
15 |
6,786,054 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1914:Rictor
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1915:Rictor
|
UTSW |
15 |
6,789,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1994:Rictor
|
UTSW |
15 |
6,805,637 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2145:Rictor
|
UTSW |
15 |
6,794,588 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2182:Rictor
|
UTSW |
15 |
6,801,685 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R2191:Rictor
|
UTSW |
15 |
6,789,095 (GRCm39) |
missense |
probably benign |
0.04 |
|
R2357:Rictor
|
UTSW |
15 |
6,813,043 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2914:Rictor
|
UTSW |
15 |
6,799,476 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3082:Rictor
|
UTSW |
15 |
6,804,338 (GRCm39) |
missense |
probably benign |
0.15 |
|
R3885:Rictor
|
UTSW |
15 |
6,789,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3900:Rictor
|
UTSW |
15 |
6,818,954 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4376:Rictor
|
UTSW |
15 |
6,816,448 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4611:Rictor
|
UTSW |
15 |
6,816,625 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4644:Rictor
|
UTSW |
15 |
6,807,416 (GRCm39) |
nonsense |
probably null |
|
|
R4718:Rictor
|
UTSW |
15 |
6,812,641 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4822:Rictor
|
UTSW |
15 |
6,821,161 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4980:Rictor
|
UTSW |
15 |
6,811,141 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5034:Rictor
|
UTSW |
15 |
6,797,576 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5179:Rictor
|
UTSW |
15 |
6,825,421 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5386:Rictor
|
UTSW |
15 |
6,818,985 (GRCm39) |
missense |
probably benign |
0.37 |
|
R5532:Rictor
|
UTSW |
15 |
6,819,046 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5549:Rictor
|
UTSW |
15 |
6,816,391 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5715:Rictor
|
UTSW |
15 |
6,780,197 (GRCm39) |
nonsense |
probably null |
|
|
R5733:Rictor
|
UTSW |
15 |
6,812,585 (GRCm39) |
missense |
probably benign |
|
|
R5822:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5848:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5849:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5850:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5854:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5855:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5856:Rictor
|
UTSW |
15 |
6,823,487 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5936:Rictor
|
UTSW |
15 |
6,813,642 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6155:Rictor
|
UTSW |
15 |
6,823,458 (GRCm39) |
missense |
probably benign |
0.44 |
|
R6394:Rictor
|
UTSW |
15 |
6,798,790 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R6549:Rictor
|
UTSW |
15 |
6,825,656 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6611:Rictor
|
UTSW |
15 |
6,780,140 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6657:Rictor
|
UTSW |
15 |
6,788,977 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6705:Rictor
|
UTSW |
15 |
6,823,493 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6819:Rictor
|
UTSW |
15 |
6,825,517 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6985:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R6989:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7016:Rictor
|
UTSW |
15 |
6,804,361 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7030:Rictor
|
UTSW |
15 |
6,737,934 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7066:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7067:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7216:Rictor
|
UTSW |
15 |
6,798,782 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7396:Rictor
|
UTSW |
15 |
6,816,462 (GRCm39) |
missense |
not run |
|
|
R7449:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7450:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7452:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7616:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7620:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7643:Rictor
|
UTSW |
15 |
6,798,750 (GRCm39) |
nonsense |
probably null |
|
|
R7699:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7700:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7749:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7750:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7751:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7753:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7841:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7894:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7897:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7898:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7937:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7944:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8062:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8063:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8094:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8119:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8134:Rictor
|
UTSW |
15 |
6,801,635 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8166:Rictor
|
UTSW |
15 |
6,798,815 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8324:Rictor
|
UTSW |
15 |
6,775,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8343:Rictor
|
UTSW |
15 |
6,807,800 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8691:Rictor
|
UTSW |
15 |
6,816,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8859:Rictor
|
UTSW |
15 |
6,813,067 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8953:Rictor
|
UTSW |
15 |
6,823,928 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8977:Rictor
|
UTSW |
15 |
6,812,566 (GRCm39) |
missense |
probably benign |
|
|
R9008:Rictor
|
UTSW |
15 |
6,801,610 (GRCm39) |
splice site |
probably benign |
|
|
R9369:Rictor
|
UTSW |
15 |
6,773,848 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9563:Rictor
|
UTSW |
15 |
6,797,562 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9695:Rictor
|
UTSW |
15 |
6,816,010 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0020:Rictor
|
UTSW |
15 |
6,785,963 (GRCm39) |
missense |
probably benign |
0.32 |
|
X0060:Rictor
|
UTSW |
15 |
6,816,033 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- CGCTCTCTGAAGAACCTCCGAATAC -3'
(R):5'- ACTTAGCAGTCATCACGGGCTCTC -3'
Sequencing Primer
(F):5'- GAATACGAGGTAAGCCCGCTC -3'
(R):5'- GGGTCCAGCATCTGCTCTTG -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation