Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL00703:Palmd'

12900

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Palmd

Ensembl Gene

ENSMUSG00000033377

Gene Name

palmdelphin

Synonyms

4631423C22Rik, PALML

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.073) question?

Stock #

IGL00703

Quality Score

Status

Chromosome

Chromosomal Location

116711907-116762636 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to G at 116721040 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000122725 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000040097] [ENSMUST00000119557] [ENSMUST00000143611]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000040097

SMART Domains

Protein: ENSMUSP00000044693
Gene: ENSMUSG00000033377

Domain	Start	End	E-Value	Type
low complexity region	29	44	N/A	INTRINSIC
Pfam:Paralemmin	65	512	3.6e-57	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000119557

SMART Domains

Protein: ENSMUSP00000113107
Gene: ENSMUSG00000033377

Domain	Start	End	E-Value	Type
low complexity region	29	44	N/A	INTRINSIC
Pfam:Paralemmin	64	278	6.6e-14	PFAM
Pfam:Paralemmin	323	515	1.3e-15	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000143611

SMART Domains

Protein: ENSMUSP00000122725
Gene: ENSMUSG00000033377

Domain	Start	End	E-Value	Type
coiled coil region	4	94	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 19 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam26b	A	T	8: 43,973,216 (GRCm39)	D595E	probably damaging	Het
Bdkrb2	T	C	12: 105,558,614 (GRCm39)	V285A	probably benign	Het
Cdc42se1	A	G	3: 95,139,856 (GRCm39)		probably benign	Het
Dimt1	T	C	13: 107,089,938 (GRCm39)		probably benign	Het
Gpx8	T	C	13: 113,182,047 (GRCm39)	N129D	possibly damaging	Het
Ikbke	A	T	1: 131,183,039 (GRCm39)		probably benign	Het
Mast4	C	A	13: 102,907,275 (GRCm39)	E558*	probably null	Het
Mybpc1	T	C	10: 88,360,970 (GRCm39)		probably null	Het
Nrg3	T	A	14: 38,092,758 (GRCm39)	D609V	probably damaging	Het
Ppp1r3a	T	C	6: 14,718,407 (GRCm39)	T836A	probably benign	Het
Ptms	T	C	6: 124,891,919 (GRCm39)		probably benign	Het
Rnf170	A	G	8: 26,615,946 (GRCm39)	N79S	probably damaging	Het
Slc15a2	T	C	16: 36,578,153 (GRCm39)	I379V	probably benign	Het
Slco1b2	A	T	6: 141,601,078 (GRCm39)	T134S	probably damaging	Het
Tg	G	A	15: 66,568,338 (GRCm39)	V1342I	probably benign	Het
Tsc22d1	A	G	14: 76,742,268 (GRCm39)	R38G	possibly damaging	Het
Ufl1	A	G	4: 25,280,631 (GRCm39)	V72A	possibly damaging	Het
Ugt2b35	A	T	5: 87,156,051 (GRCm39)	Y381F	probably benign	Het
Vil1	T	C	1: 74,463,119 (GRCm39)	L434P	possibly damaging	Het

Other mutations in Palmd

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01112:Palmd	APN	3	116,717,922 (GRCm39)	missense	probably damaging	1.00
IGL01484:Palmd	APN	3	116,746,794 (GRCm39)	splice site	probably benign
IGL01527:Palmd	APN	3	116,720,837 (GRCm39)	nonsense	probably null
IGL01561:Palmd	APN	3	116,717,742 (GRCm39)	missense	probably damaging	0.99
IGL01975:Palmd	APN	3	116,717,283 (GRCm39)	missense	probably benign	0.24
R0107:Palmd	UTSW	3	116,717,725 (GRCm39)	missense	probably damaging	1.00
R1099:Palmd	UTSW	3	116,716,874 (GRCm39)	missense	possibly damaging	0.71
R1552:Palmd	UTSW	3	116,741,689 (GRCm39)	splice site	probably benign
R1613:Palmd	UTSW	3	116,717,153 (GRCm39)	missense	probably damaging	1.00
R1710:Palmd	UTSW	3	116,717,306 (GRCm39)	missense	probably damaging	1.00
R2090:Palmd	UTSW	3	116,721,083 (GRCm39)	missense	probably damaging	1.00
R2869:Palmd	UTSW	3	116,717,400 (GRCm39)	missense	possibly damaging	0.60
R2869:Palmd	UTSW	3	116,717,400 (GRCm39)	missense	possibly damaging	0.60
R2870:Palmd	UTSW	3	116,717,400 (GRCm39)	missense	possibly damaging	0.60
R2870:Palmd	UTSW	3	116,717,400 (GRCm39)	missense	possibly damaging	0.60
R2871:Palmd	UTSW	3	116,717,400 (GRCm39)	missense	possibly damaging	0.60
R2871:Palmd	UTSW	3	116,717,400 (GRCm39)	missense	possibly damaging	0.60
R2872:Palmd	UTSW	3	116,717,400 (GRCm39)	missense	possibly damaging	0.60
R2872:Palmd	UTSW	3	116,717,400 (GRCm39)	missense	possibly damaging	0.60
R2873:Palmd	UTSW	3	116,717,400 (GRCm39)	missense	possibly damaging	0.60
R3774:Palmd	UTSW	3	116,721,312 (GRCm39)	missense	probably damaging	1.00
R3981:Palmd	UTSW	3	116,717,472 (GRCm39)	missense	probably benign	0.01
R3982:Palmd	UTSW	3	116,717,472 (GRCm39)	missense	probably benign	0.01
R3983:Palmd	UTSW	3	116,717,472 (GRCm39)	missense	probably benign	0.01
R4955:Palmd	UTSW	3	116,717,873 (GRCm39)	missense	probably damaging	1.00
R5103:Palmd	UTSW	3	116,721,070 (GRCm39)	missense	probably damaging	1.00
R5261:Palmd	UTSW	3	116,717,009 (GRCm39)	missense	probably benign	0.04
R5265:Palmd	UTSW	3	116,717,498 (GRCm39)	missense	possibly damaging	0.67
R5292:Palmd	UTSW	3	116,717,393 (GRCm39)	missense	probably benign	0.00
R5499:Palmd	UTSW	3	116,717,481 (GRCm39)	missense	probably benign	0.01
R5597:Palmd	UTSW	3	116,717,225 (GRCm39)	missense	probably damaging	1.00
R5666:Palmd	UTSW	3	116,717,750 (GRCm39)	missense	possibly damaging	0.55
R5817:Palmd	UTSW	3	116,712,272 (GRCm39)	missense	probably benign	0.01
R6843:Palmd	UTSW	3	116,717,864 (GRCm39)	missense	probably damaging	1.00
R6854:Palmd	UTSW	3	116,717,112 (GRCm39)	missense	probably benign	0.06
R7052:Palmd	UTSW	3	116,717,012 (GRCm39)	missense	probably benign	0.30
R7450:Palmd	UTSW	3	116,721,292 (GRCm39)	missense	probably damaging	1.00
R8876:Palmd	UTSW	3	116,720,899 (GRCm39)	missense	probably damaging	1.00
R9655:Palmd	UTSW	3	116,716,840 (GRCm39)	makesense	probably null
R9681:Palmd	UTSW	3	116,717,120 (GRCm39)	missense	probably benign	0.22
Z1177:Palmd	UTSW	3	116,717,151 (GRCm39)	missense	probably damaging	1.00

Posted On

2012-12-06